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Volumn 2015, Issue , 2015, Pages

Targeting of prosurvival pathways as therapeutic approaches against primary effusion lymphomas: Past, present, and future

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE 2; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; ANTIVIRUS AGENT;

EID: 84933073693     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/104912     Document Type: Review
Times cited : (13)

References (52)
  • 1
    • 0036561909 scopus 로고    scopus 로고
    • AIDS-related malignancies
    • C. Boshoff and R. Weiss, "AIDS-related malignancies, " Nature Reviews Cancer, vol. 2, no. 5, pp. 373-382, 2002.
    • (2002) Nature Reviews Cancer , vol.2 , Issue.5 , pp. 373-382
    • Boshoff, C.1    Weiss, R.2
  • 2
    • 0029974841 scopus 로고    scopus 로고
    • Primary effusion lymphoma: A distinct clinicopathologic entity associated with theKaposi's sarcoma-associated herpes virus
    • R.G.Nador, E.Cesarman, A.Chadburn et al., "Primary effusion lymphoma: a distinct clinicopathologic entity associated with theKaposi's sarcoma-associated herpes virus, " Blood, vol. 88, no. 2, pp. 645-656, 1996.
    • (1996) Blood , vol.88 , Issue.2 , pp. 645-656
    • Nador, R.G.1    Cesarman, E.2    Chadburn, A.3
  • 3
    • 0029957877 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus in non-AIDS-related lymphomas occurring in body cavities
    • E. Cesarman, R. G. Nador, K. Aozasa, G. Delsol, J.W. Said, and D. M. Knowles, "Kaposi's sarcoma-associated herpesvirus in non-AIDS-related lymphomas occurring in body cavities, " The American Journal of Pathology, vol. 149, no. 1, pp. 53-57, 1996.
    • (1996) The American Journal of Pathology , vol.149 , Issue.1 , pp. 53-57
    • Cesarman, E.1    Nador, R.G.2    Aozasa, K.3    Delsol, G.4    Said, J.W.5    Knowles, D.M.6
  • 4
    • 11144228387 scopus 로고    scopus 로고
    • Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association
    • W. Fan, D. Bubman, A.Chadburn, W. J. Harrington Jr., E. Cesarman, and D. M. Knowles, "Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association, " Journal of Virology, vol. 79, no. 2, pp. 1244-1251, 2005.
    • (2005) Journal of Virology , vol.79 , Issue.2 , pp. 1244-1251
    • Fan, W.1    Bubman, D.2    Chadburn, A.3    Harrington, W.J.4    Cesarman, E.5    Knowles, D.M.6
  • 5
    • 0033654484 scopus 로고    scopus 로고
    • Novel strategies toward the development of an effective vaccine to prevent human immunodeficiency virus infection or acquired immunodeficiency virus
    • B. Ensoli and A. Cafaro, "Novel strategies toward the development of an effective vaccine to prevent human immunodeficiency virus infection or acquired immunodeficiency virus, " AIDS Clinical Review, vol. 18, no. 4, pp. 23-61, 2000.
    • (2000) AIDS Clinical Review , vol.18 , Issue.4 , pp. 23-61
    • Ensoli, B.1    Cafaro, A.2
  • 6
    • 0032915798 scopus 로고    scopus 로고
    • Constitutive cytokine production by primary effusion (body cavitybased) lymphoma-derived cell lines
    • H. G. Drexler, C. Meyer, G. Gaidano, and A. Carbone, "Constitutive cytokine production by primary effusion (body cavitybased) lymphoma-derived cell lines, " Leukemia, vol. 13, no. 4, pp. 634-640, 1999.
    • (1999) Leukemia , vol.13 , Issue.4 , pp. 634-640
    • Drexler, H.G.1    Meyer, C.2    Gaidano, G.3    Carbone, A.4
  • 7
    • 42349100920 scopus 로고    scopus 로고
    • KSHV-transformed primary effusion lymphoma cells induce a VEGFdependent angiogenesis and establish functional gap junctions with endothelial cells
    • L. Haddad, H. El Hajj, R. Abou-Merhi et al., "KSHV-transformed primary effusion lymphoma cells induce a VEGFdependent angiogenesis and establish functional gap junctions with endothelial cells, " Leukemia, vol. 22, no. 4, pp. 826-834, 2008.
    • (2008) Leukemia , vol.22 , Issue.4 , pp. 826-834
    • Haddad, L.1    El Hajj, H.2    Abou-Merhi, R.3
  • 8
    • 0032857038 scopus 로고    scopus 로고
    • Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi's sarcoma herpesvirusassociated infected primary effusion lymphoma cells
    • K. D. Jones, Y. Aoki, Y. Chang, P. S. Moore, R. Yarchoan, and G. Tosato, "Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi's sarcoma herpesvirusassociated infected primary effusion lymphoma cells, " Blood, vol. 94, no. 8, pp. 2871-2879, 1999.
    • (1999) Blood , vol.94 , Issue.8 , pp. 2871-2879
    • Jones, K.D.1    Aoki, Y.2    Chang, Y.3    Moore, P.S.4    Yarchoan, R.5    Tosato, G.6
  • 9
    • 0032703834 scopus 로고    scopus 로고
    • KSHV-encoded viral IL-6 activatesmultiple human IL-6 signaling pathways
    • J. Osborne, P. S. Moore, and Y. Chang, "KSHV-encoded viral IL-6 activatesmultiple human IL-6 signaling pathways, " Human Immunology, vol. 60, no. 10, pp. 921-927, 1999.
    • (1999) Human Immunology , vol.60 , Issue.10 , pp. 921-927
    • Osborne, J.1    Moore, P.S.2    Chang, Y.3
  • 10
    • 84883347713 scopus 로고    scopus 로고
    • The viral KSHV chemokine vMIP-II inhibits the migration of naive and activated human NK cells by antagonizing two distinct chemokine receptors
    • Article ID e1003568
    • R. Yamin, N. S. Kaynan, A. Glasner et al., "The viral KSHV chemokine vMIP-II inhibits the migration of naive and activated human NK cells by antagonizing two distinct chemokine receptors, " PLoS Pathogens, vol. 9, no. 8, Article ID e1003568, 2013.
    • (2013) PLoS Pathogens , vol.9 , Issue.8
    • Yamin, R.1    Kaynan, N.S.2    Glasner, A.3
  • 11
    • 85047695527 scopus 로고    scopus 로고
    • Constitutive stat3 activity up-regulates VEGF expression and tumor angiogenesis
    • G.Niu, K. L.Wright, M.Huang et al., "Constitutive stat3 activity up-regulates VEGF expression and tumor angiogenesis, " Oncogene, vol. 21, no. 13, pp. 2000-2008, 2002.
    • (2002) Oncogene , vol.21 , Issue.13 , pp. 2000-2008
    • Niu, G.1    Wright, L.K.2    Huang, M.3
  • 12
    • 84873307871 scopus 로고    scopus 로고
    • Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation
    • D. A. Braun, M. Fribourg, and S. C. Sealfon, "Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation, " The Journal of Biological Chemistry, vol. 288, no. 5, pp. 2986-2993, 2013.
    • (2013) The Journal of Biological Chemistry , vol.288 , Issue.5 , pp. 2986-2993
    • Braun, D.A.1    Fribourg, M.2    Sealfon, S.C.3
  • 13
    • 27644477618 scopus 로고    scopus 로고
    • Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma
    • S. Uddin, A. R. Hussain, P. S. Manogaran et al., "Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma, " Oncogene, vol. 24, no. 47, pp. 7022-7030, 2005.
    • (2005) Oncogene , vol.24 , Issue.47 , pp. 7022-7030
    • Uddin, S.1    Hussain, A.R.2    Manogaran, P.S.3
  • 14
    • 0037441888 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
    • Y. Aoki, G. M. Feldman, and G. Tosato, "Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma, " Blood, vol. 101, no. 4, pp. 1535-1542, 2003.
    • (2003) Blood , vol.101 , Issue.4 , pp. 1535-1542
    • Aoki, Y.1    Feldman, G.M.2    Tosato, G.3
  • 15
    • 84857879286 scopus 로고    scopus 로고
    • Primary effusion lymphoma cell death induced by bortezomib and AG 490 activates dendritic cells through CD91
    • Article ID e31732
    • M. Cirone, L. Di Renzo, L. V. Lotti et al., "Primary effusion lymphoma cell death induced by bortezomib and AG 490 activates dendritic cells through CD91, " PLoS ONE, vol. 7, no. 3, Article ID e31732, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.3
    • Cirone, M.1    Di Renzo, L.2    Lotti, L.V.3
  • 16
    • 84868676333 scopus 로고    scopus 로고
    • Targeting COX-2/PGE2 pathway inHIPK2 knockdown cancer cells: Impact on dendritic cell maturation
    • Article ID e48342
    • A. Garufi, G. Pistritto, C. Ceci et al., "Targeting COX-2/PGE2 pathway inHIPK2 knockdown cancer cells: impact on dendritic cell maturation, " PLoS ONE, vol. 7, no. 11, Article ID e48342, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.11
    • Garufi, A.1    Pistritto, G.2    Ceci, C.3
  • 17
    • 79952283465 scopus 로고    scopus 로고
    • How to improve the immunogenicity of chemotherapy and radiotherapy
    • Y. Ma, R. Conforti, L. Aymeric et al., "How to improve the immunogenicity of chemotherapy and radiotherapy, " Cancer and Metastasis Reviews, vol. 30, no. 1, pp. 71-82, 2011.
    • (2011) Cancer and Metastasis Reviews , vol.30 , Issue.1 , pp. 71-82
    • Ma, Y.1    Conforti, R.2    Aymeric, L.3
  • 18
    • 80755126873 scopus 로고    scopus 로고
    • Cell death in themaintenance and abrogation of tolerance: The five Ws of dying cells
    • T. S. Griffith and T. A. Ferguson, "Cell death in themaintenance and abrogation of tolerance: the five Ws of dying cells, " Immunity, vol. 35, no. 4, pp. 456-466, 2011.
    • (2011) Immunity , vol.35 , Issue.4 , pp. 456-466
    • Griffith, T.S.1    Ferguson, T.A.2
  • 19
    • 34347230533 scopus 로고    scopus 로고
    • Elevated interleukin-6 and G-CSF in human pancreatic cancer cell conditionedmediumsuppress dendritic cell differentiation and activation
    • U. Bharadwaj, M. Li, R. Zhang, C. Chen, and Q. Yao, "Elevated interleukin-6 and G-CSF in human pancreatic cancer cell conditionedmediumsuppress dendritic cell differentiation and activation, " Cancer Research, vol. 67, no. 11, pp. 5479-5488, 2007.
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5479-5488
    • Bharadwaj, U.1    Li, M.2    Zhang, R.3    Chen, C.4    Yao, Q.5
  • 20
    • 33846017974 scopus 로고    scopus 로고
    • IL-12 p35 silenced dendritic cells modulate immune responses by blocking IL-12 signaling through JAK-STAT pathway in T lymphocytes
    • H. Xu, Y. Zhang, Y. Hua, T. Chen, H. Wang, and W.Wu, "IL-12 p35 silenced dendritic cells modulate immune responses by blocking IL-12 signaling through JAK-STAT pathway in T lymphocytes, " Biochemical and Biophysical Research Communications, vol. 353, no. 3, pp. 812-816, 2007.
    • (2007) Biochemical and Biophysical Research Communications , vol.353 , Issue.3 , pp. 812-816
    • Xu, H.1    Zhang, Y.2    Hua, Y.3    Chen, T.4    Wang, H.5    Wu, W.6
  • 21
    • 79953787909 scopus 로고    scopus 로고
    • Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines
    • article 125
    • S. L. Fossey, M. D. Bear, W.C.Kisseberth, M. Pennell, andC.A. London, "Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines, " BMC Cancer, vol. 11, article 125, 2011.
    • (2011) BMC Cancer , vol.11
    • Fossey, S.L.1    Bear, M.D.2    Kisseberth, W.C.3    Pennell, M.4    London, C.A.5
  • 22
    • 38749092254 scopus 로고    scopus 로고
    • Oncostatin M receptor- mutations underlie familial primary localized cutaneous amyloidosis
    • K. Arita, A. P. South, G. Hans-Filho et al., "Oncostatin M receptor- mutations underlie familial primary localized cutaneous amyloidosis, " The American Journal of Human Genetics, vol. 82, no. 1, pp. 73-80, 2008.
    • (2008) The American Journal of Human Genetics , vol.82 , Issue.1 , pp. 73-80
    • Arita, K.1    South, A.P.2    Hans-Filho, G.3
  • 23
    • 84874251703 scopus 로고    scopus 로고
    • AKTivation of PI3K/AKT/mTOR signaling pathway by KSHV
    • Article ID Article 401
    • A. P. Bhatt and B. Damania, "AKTivation of PI3K/AKT/mTOR signaling pathway by KSHV, " Frontiers in Immunology, vol. 3, Article ID Article 401, 2012.
    • (2012) Frontiers in Immunology , vol.3
    • Bhatt, A.P.1    Damania, B.2
  • 24
    • 0842304506 scopus 로고    scopus 로고
    • The K1 protein of Kaposi's Sarcoma-Associated Herpesvirus activates the AKT signaling pathway
    • C. C. Tomlinson and B. Damania, "The K1 protein of Kaposi's Sarcoma-Associated Herpesvirus activates the AKT signaling pathway, " Journal of Virology, vol. 78, no. 4, pp. 1918-1927, 2004.
    • (2004) Journal of Virology , vol.78 , Issue.4 , pp. 1918-1927
    • Tomlinson, C.C.1    Damania, B.2
  • 25
    • 17144362835 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3′-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells
    • S. Uddin, A. R. Hussain, K. A. Al-Hussein et al., "Inhibition of phosphatidylinositol 3′-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells, " Clinical Cancer Research, vol. 11, no. 8, pp. 3102-3108, 2005.
    • (2005) Clinical Cancer Research , vol.11 , Issue.8 , pp. 3102-3108
    • Uddin, S.1    Hussain, A.R.2    Al-Hussein, K.A.3
  • 26
    • 77953932867 scopus 로고    scopus 로고
    • Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas
    • A. P. Bhatt, P. M. Bhende, S.-H. Sin, D. Roy, D. P. Dittmer, and B. Damania, "Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas, " Blood, vol. 115, no. 22, pp. 4455-4463, 2010.
    • (2010) Blood , vol.115 , Issue.22 , pp. 4455-4463
    • Bhatt, A.P.1    Bhende, P.M.2    Sin, S.-H.3    Roy, D.4    Dittmer, D.P.5    Damania, B.6
  • 27
    • 84885992095 scopus 로고    scopus 로고
    • Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance andGLUT-1 plasmamembrane exposure in THP-1monocytic cell line
    • article 79
    • R. Gonnella, R. Santarelli, A. Farina et al., "Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance andGLUT-1 plasmamembrane exposure in THP-1monocytic cell line, " Journal of Experimental and Clinical Cancer Research, vol. 32, no. 1, article 79, 2013.
    • (2013) Journal of Experimental and Clinical Cancer Research , vol.32 , Issue.1
    • Gonnella, R.1    Santarelli, R.2    Farina, A.3
  • 28
    • 33847390842 scopus 로고    scopus 로고
    • Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling
    • S.-H. Sin, D. Roy, L. Wang et al., "Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling, " Blood, vol. 109, no. 5, pp. 2165-2173, 2007.
    • (2007) Blood , vol.109 , Issue.5 , pp. 2165-2173
    • Sin, S.-H.1    Roy, D.2    Wang, L.3
  • 29
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • G. L. Johnson and R. Lapadat, "Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases, " Science, vol. 298, no. 5600, pp. 1911-1912, 2002.
    • (2002) Science , vol.298 , Issue.5600 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 30
    • 67649438633 scopus 로고    scopus 로고
    • Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stressinduced cell cycle progression and cell death in human hepatocellular carcinoma cells
    • R. Dai, R. Chen, and H. Li, "Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stressinduced cell cycle progression and cell death in human hepatocellular carcinoma cells, " International Journal of Oncology, vol. 34, no. 6, pp. 1749-1757, 2009.
    • (2009) International Journal of Oncology , vol.34 , Issue.6 , pp. 1749-1757
    • Dai, R.1    Chen, R.2    Li, H.3
  • 31
    • 84884626755 scopus 로고    scopus 로고
    • JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells
    • Article ID e75965
    • M. Granato, R. Santarelli, L. V. Lotti et al., "JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells, " PLoS ONE, vol. 8, no. 9, Article ID e75965, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.9
    • Granato, M.1    Santarelli, R.2    Lotti, L.V.3
  • 33
    • 0034287445 scopus 로고    scopus 로고
    • Inhibition of NF-B induces apoptosis of KSHV-infected primary effusion lymphoma cells
    • S. A. Keller, E. J. Schattner, and E. Cesarman, "Inhibition of NF-B induces apoptosis of KSHV-infected primary effusion lymphoma cells, " Blood, vol. 96, no. 7, pp. 2537-2542, 2000.
    • (2000) Blood , vol.96 , Issue.7 , pp. 2537-2542
    • Keller, S.A.1    Schattner, E.J.2    Cesarman, E.3
  • 34
    • 84884566110 scopus 로고    scopus 로고
    • A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP k13-induced NF-B
    • R. Gopalakrishnan, H. Matta, and P.M. Chaudhary, "A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP k13-induced NF-B, " Clinical Cancer Research, vol. 19, no. 18, pp. 5016-5026, 2013.
    • (2013) Clinical Cancer Research , vol.19 , Issue.18 , pp. 5016-5026
    • Gopalakrishnan, R.1    Matta, H.2    Chaudhary, P.M.3
  • 35
    • 24644517593 scopus 로고    scopus 로고
    • The proteasome inhibitor Bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells
    • H. Matta and P. M. Chaudhary, "The proteasome inhibitor Bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells, " Cancer Biology and Therapy, vol. 4, no. 1, pp. 77-82, 2005.
    • (2005) Cancer Biology and Therapy , vol.4 , Issue.1 , pp. 77-82
    • Matta, H.1    Chaudhary, P.M.2
  • 37
    • 84881036485 scopus 로고    scopus 로고
    • Activation of dendritic cells by tumor cell death
    • M.Cirone, L. Di Renzo, L. V. Lotti et al., "Activation of dendritic cells by tumor cell death, " OncoImmunology, vol. 1, no. 7, pp. 1218-1219, 2012.
    • (2012) OncoImmunology , vol.1 , Issue.7 , pp. 1218-1219
    • Cirone, M.1    Di Renzo, L.2    Lotti, L.V.3
  • 38
    • 33846208233 scopus 로고    scopus 로고
    • STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90 and in multiple myeloma cells, which critically contribute to tumor-cell survival
    • M. Chatterjee, S. Jain, T. Stühmer et al., "STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90 and in multiple myeloma cells, which critically contribute to tumor-cell survival, " Blood, vol. 109, no. 2, pp. 720-728, 2007.
    • (2007) Blood , vol.109 , Issue.2 , pp. 720-728
    • Chatterjee, M.1    Jain, S.2    Stühmer, T.3
  • 39
    • 84879589788 scopus 로고    scopus 로고
    • The PI3k/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma
    • M. Chatterjee, M. Andrulis, T. Stühmer et al., "The PI3k/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma, " Haematologica, vol. 98, no. 7, pp. 1132-1141, 2013.
    • (2013) Haematologica , vol.98 , Issue.7 , pp. 1132-1141
    • Chatterjee, M.1    Andrulis, M.2    Stühmer, T.3
  • 40
    • 84881080283 scopus 로고    scopus 로고
    • HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma
    • article e730
    • M. Granato, V. Lacconi, M. Peddis et al., "HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma, " Cell Death and Disease, vol. 4, no. 7, article e730, 2013.
    • (2013) Cell Death and Disease , vol.4 , Issue.7
    • Granato, M.1    Lacconi, V.2    Peddis, M.3
  • 41
    • 84861205536 scopus 로고    scopus 로고
    • The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells
    • C. Higashi, C. Saji, K. Yamada et al., "The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells, " Biological and Pharmaceutical Bulletin, vol. 35, no. 5, pp. 725-730, 2012.
    • (2012) Biological and Pharmaceutical Bulletin , vol.35 , Issue.5 , pp. 725-730
    • Higashi, C.1    Saji, C.2    Yamada, K.3
  • 42
    • 84887440198 scopus 로고    scopus 로고
    • Targeting theHsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies
    • U.Nayar, P.Lu, R. L.Goldsteinet al., "Targeting theHsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies, " Blood, vol. 122, no. 16, pp. 2837-2847, 2013.
    • (2013) Blood , vol.122 , Issue.16 , pp. 2837-2847
    • Nayar, U.1    Lu, P.2    Goldstein, R.L.3
  • 43
    • 84859614874 scopus 로고    scopus 로고
    • The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases
    • B. Lamottke, M. Kaiser, M. Mieth et al., "The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases, " European Journal of Haematology, vol. 88, no. 5, pp. 406-415, 2012.
    • (2012) European Journal of Haematology , vol.88 , Issue.5 , pp. 406-415
    • Lamottke, B.1    Kaiser, M.2    Mieth, M.3
  • 44
    • 0042337395 scopus 로고    scopus 로고
    • Kaposi's sarcomaassociated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile
    • R. G. Jenner, K. Maillard, N. Cattini et al., "Kaposi's sarcomaassociated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile, " Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 18, pp. 10399-10404, 2003.
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.18 , pp. 10399-10404
    • Jenner, R.G.1    Maillard, K.2    Cattini, N.3
  • 45
    • 77954480306 scopus 로고    scopus 로고
    • Enhancement of autophagy during lytic replication by the Kaposi's sarcomaassociated herpesvirus replication and transcription activator
    • H.-J. Wen, Z. Yang, Y. Zhou, and C.Wood, "Enhancement of autophagy during lytic replication by the Kaposi's sarcomaassociated herpesvirus replication and transcription activator, " Journal of Virology, vol. 84, no. 15, pp. 7448-7458, 2010.
    • (2010) Journal of Virology , vol.84 , Issue.15 , pp. 7448-7458
    • Wen, H.-J.1    Yang, Z.2    Zhou, Y.3    Wood, C.4
  • 46
    • 84858739354 scopus 로고    scopus 로고
    • Regulation of NF-B by ubiquitination and degradation of the IBs
    • N. Kanarek and Y. Ben-Neriah, "Regulation of NF-B by ubiquitination and degradation of the IBs, " Immunological Reviews, vol. 246, no. 1, pp. 77-94, 2012.
    • (2012) Immunological Reviews , vol.246 , Issue.1 , pp. 77-94
    • Kanarek, N.1    Ben-Neriah, Y.2
  • 47
    • 84897592184 scopus 로고    scopus 로고
    • STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells
    • article 4241
    • R. Santarelli, R. Gonnella, G. Di Giovenale et al., "STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells, " Scientific Reports, vol. 4, article 4241, 2014.
    • (2014) Scientific Reports , vol.4
    • Santarelli, R.1    Gonnella, R.2    Di Giovenale, G.3
  • 48
    • 84894528347 scopus 로고    scopus 로고
    • Sangivamycin induces apoptosis by suppressing Erk signaling in primary effusion lymphoma cells
    • K. Wakao, T. Watanabe, T. Takadama et al., "Sangivamycin induces apoptosis by suppressing Erk signaling in primary effusion lymphoma cells, " Biochemical and Biophysical Research Communications, vol. 444, no. 2, pp. 135-140, 2014.
    • (2014) Biochemical and Biophysical Research Communications , vol.444 , Issue.2 , pp. 135-140
    • Wakao, K.1    Watanabe, T.2    Takadama, T.3
  • 49
    • 77953784609 scopus 로고    scopus 로고
    • Hsp90 and Hsp40/Erdj3 are required for the expression and anti-apoptotic function of KSHV K1
    • K. W. Wen and B. Damania, "Hsp90 and Hsp40/Erdj3 are required for the expression and anti-apoptotic function of KSHV K1, " Oncogene, vol. 29, no. 24, pp. 3532-3544, 2010.
    • (2010) Oncogene , vol.29 , Issue.24 , pp. 3532-3544
    • Wen, K.W.1    Damania, B.2
  • 50
    • 84870792928 scopus 로고    scopus 로고
    • Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins
    • Article ID e1003048
    • W. Chen, S.-H. Sin, K.W.Wen, B. Damania, and D. P. Dittmer, "Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins, " PLoS Pathogens, vol. 8, no. 11, Article ID e1003048, 2012.
    • (2012) PLoS Pathogens , vol.8 , Issue.11
    • Chen, W.1    Sin, S.-H.2    Wen, K.W.3    Damania, B.4    Dittmer, D.P.5
  • 51
    • 0036022402 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: An update
    • C. Soldani and A. I. Scovassi, "Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update, " Apoptosis, vol. 7, no. 4, pp. 321-328, 2002.
    • (2002) Apoptosis , vol.7 , Issue.4 , pp. 321-328
    • Soldani, C.1    Scovassi, A.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.