Anthocyanin-rich Seoritae extract ameliorates renal lipotoxicity via activation of AMP-activated protein kinase in diabetic mice

Journal of Translational Medicine

Volumn 13, Issue 1, 2015, Pages

  Koh, Eun Sil ^a,b   Lim, Ji Hee ^b   Kim, Min Young ^b   Chung, Sungjin ^a,b   Shin, Seok Joon ^b,c   Choi, Bum Soon ^b,d   Kim, Hye Won ^e   Hwang, Seong Yeon ^f   Kim, Sae Woong ^b   Park, Cheol Whee ^b,d   Chang, Yoon Sik ^a,b  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c The Catholic University of Korea   (South Korea)

^d The Catholic University of Korea   (South Korea)

^e The Catholic University of Korea   (South Korea)

^f Korea Bio Medical Science Institute   (South Korea)

Author keywords

AMPK; Anthocyanin; Diabetic nephropathy

Indexed keywords

8 ISOPROSTANE; ACETYL COENZYME A CARBOXYLASE; ANTHOCYANIN; CHOLESTEROL; COLLAGEN TYPE 4; COPPER ZINC SUPEROXIDE DISMUTASE; ESTROGEN RELATED RECEPTOR ALPHA; FATTY ACID; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MANGANESE SUPEROXIDE DISMUTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT EXTRACT; PROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; SEORITAE EXTRACT; SIRTUIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; 8-EPI-PROSTAGLANDIN F2ALPHA; LIPID; PROSTAGLANDIN F2 ALPHA; TRANSFORMING GROWTH FACTOR BETA;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FATTY ACID BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIPOTOXICITY; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PROTEIN EXPRESSION; RENAL PROTECTION; SEORITAE; SOYBEAN; TISSUE LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYMOLOGY; KIDNEY; KIDNEY DISEASES; METABOLISM; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION; URINE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTHOCYANINS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CHOLESTEROL; COLLAGEN TYPE IV; DIABETES MELLITUS, EXPERIMENTAL; DINOPROST; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FATTY ACIDS; HUMANS; KIDNEY; KIDNEY DISEASES; LIPIDS; MALE; MICE, INBRED C57BL; OXIDATIVE STRESS; PHENOTYPE; PHOSPHORYLATION; PLANT EXTRACTS; SOYBEANS; TRANSFORMING GROWTH FACTOR BETA; TRIGLYCERIDES;

EID: 84933052292     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-015-0563-4     Document Type: Article

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