메뉴 건너뛰기




Volumn 62, Issue 11, 2013, Pages 3647-3655

Endothelial-podocyte crosstalk: The missing link between endothelial dysfunction and albuminuria in diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; GLUCOSE; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

EID: 84891712908     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0795     Document Type: Review
Times cited : (110)

References (58)
  • 1
    • 0036788492 scopus 로고    scopus 로고
    • Urinary albumin excretion predicts cardiovascular noncardiovascular mortality in general population
    • Prevention Of Renal Vascular End Stage Disease (PREVEND) Study Group
    • Hillege HL, Fidler V, Diercks GF, et al.; Prevention of Renal and Vascular End Stage Disease (PREVEND) Study Group. Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation 2002;106:1777-1782
    • (2002) Circulation , vol.106 , pp. 1777-1782
    • Hillege, H.L.1    Fidler, V.2    Diercks, G.F.3
  • 2
    • 0035948631 scopus 로고    scopus 로고
    • Albuminuria risk of cardiovascular events death heart failure in diabetic nondiabetic individuals
    • HOPE Study Investigators
    • Gerstein HC, Mann JF, Yi Q, et al.; HOPE Study Investigators. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA 2001;286:421-426
    • (2001) JAMA , vol.286 , pp. 421-426
    • Gerstein, H.C.1    Mann, J.F.2    Yi, Q.3
  • 3
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • RENAAL Study Investigators
    • Brenner BM, Cooper ME, de Zeeuw D, et al.; RENAAL Study Investigators. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345:861-869
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 4
    • 2442680120 scopus 로고    scopus 로고
    • Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL
    • de Zeeuw D, Remuzzi G, Parving HH, et al. Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int 2004;65:2309-2320
    • (2004) Kidney Int , vol.65 , pp. 2309-2320
    • De Zeeuw, D.1    Remuzzi, G.2    Parving, H.H.3
  • 5
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, doubleblind, controlled trial
    • ONTARGET investigators
    • Mann JF, Schmieder RE, McQueen M, et al.; ONTARGET investigators. Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, doubleblind, controlled trial. Lancet 2008;372:547-553
    • (2008) Lancet , vol.372 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3
  • 6
    • 42049107348 scopus 로고    scopus 로고
    • Telmisartan, ramipril, or both in patients at high risk for vascular events
    • ONTARGET Investigators
    • Yusuf S, Teo KK, Pogue J, et al.; ONTARGET Investigators. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 2008;358:1547-1559
    • (2008) N Engl J Med , vol.358 , pp. 1547-1559
    • Yusuf, S.1    Teo, K.K.2    Pogue, J.3
  • 7
    • 44849114597 scopus 로고    scopus 로고
    • Aliskiren combined with losartan in type 2 diabetes and nephropathy
    • AVOID Study Investigators
    • Parving HH, Persson F, Lewis JB, Lewis EJ, Hollenberg NK; AVOID Study Investigators. Aliskiren combined with losartan in type 2 diabetes and nephropathy. N Engl J Med 2008;358:2433-2446
    • (2008) N Engl J Med , vol.358 , pp. 2433-2446
    • Parving, H.H.1    Persson, F.2    Lewis, J.B.3    Lewis, E.J.4    Hollenberg, N.K.5
  • 8
    • 84869492851 scopus 로고    scopus 로고
    • Cardiorenal end points in a trial of aliskiren for type 2 diabetes
    • ALTITUDE Investigators
    • Parving HH, Brenner BM, McMurray JJ, et al.; ALTITUDE Investigators. Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N Engl J Med 2012;367:2204-2213
    • (2012) N Engl J Med , vol.367 , pp. 2204-2213
    • Parving, H.H.1    Brenner, B.M.2    McMurray, J.J.3
  • 9
    • 77949877308 scopus 로고    scopus 로고
    • Avosentan for overt diabetic nephropathy
    • ASCEND Study Group.
    • Mann JF, Green D, Jamerson K, et al.; ASCEND Study Group. Avosentan for overt diabetic nephropathy. J Am Soc Nephrol 2010;21:527-535
    • (2010) J Am Soc Nephrol , vol.21 , pp. 527-535
    • Mann, J.F.1    Green, D.2    Jamerson, K.3
  • 11
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813-820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 14
    • 0026696942 scopus 로고
    • Urinary albumin excretion, cardiovascular disease, and endothelial dysfunction in non-insulin-dependent diabetes mellitus
    • Stehouwer CD, Nauta JJ, Zeldenrust GC, Hackeng WH, Donker AJ, den Ottolander GJ. Urinary albumin excretion, cardiovascular disease, and endothelial dysfunction in non-insulin-dependent diabetes mellitus. Lancet 1992;340:319-323
    • (1992) Lancet , vol.340 , pp. 319-323
    • Stehouwer, C.D.1    Nauta, J.J.2    Zeldenrust, G.C.3    Hackeng, W.H.4    Donker, A.J.5    Den Ottolander, G.J.6
  • 15
    • 84874005376 scopus 로고    scopus 로고
    • Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx
    • Singh A, Ramnath RD, Foster RR, et al. Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx. PLoS ONE 2013;8:e55852
    • (2013) PLoS ONE , vol.8
    • Singh, A.1    Ramnath, R.D.2    Foster, R.R.3
  • 16
    • 0141652006 scopus 로고    scopus 로고
    • Glomerular endotheliosis in normal pregnancy and pre-eclampsia
    • Strevens H, Wide-Swensson D, Hansen A, et al. Glomerular endotheliosis in normal pregnancy and pre-eclampsia. BJOG 2003;110:831-836
    • (2003) BJOG , vol.110 , pp. 831-836
    • Strevens, H.1    Wide-Swensson, D.2    Hansen, A.3
  • 17
    • 84863012126 scopus 로고    scopus 로고
    • The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice
    • Petruzziello-Pellegrini TN, Yuen DA, Page AV, et al. The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice. J Clin Invest 2012;122: 759-776
    • (2012) J Clin Invest , vol.122 , pp. 759-776
    • Petruzziello-Pellegrini, T.N.1    Yuen, D.A.2    Page, A.V.3
  • 18
    • 0033366679 scopus 로고    scopus 로고
    • Structure of the gene for congenital nephrotic syndrome of the finnish type (NPHS1) and characterization of mutations
    • Lenkkeri U, Männikkö M, McCready P, et al. Structure of the gene for congenital nephrotic syndrome of the finnish type (NPHS1) and characterization of mutations. Am J Hum Genet 1999;64:51-61
    • (1999) Am J Hum Genet , vol.64 , pp. 51-61
    • Lenkkeri, U.1    Männikkö, M.2    McCready, P.3
  • 19
    • 0036789206 scopus 로고    scopus 로고
    • Podocyte number in normotensive type 1 diabetic patients with albuminuria
    • White KE, Bilous RW, Marshall SM, et al. Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes 2002;51:3083-3089
    • (2002) Diabetes , vol.51 , pp. 3083-3089
    • White, K.E.1    Bilous, R.W.2    Marshall, S.M.3
  • 20
    • 0032710966 scopus 로고    scopus 로고
    • Podocyte number predicts long-term urinary albumin excretion in Pima Indians with type II diabetes and microalbuminuria
    • Meyer TW, Bennett PH, Nelson RG. Podocyte number predicts long-term urinary albumin excretion in Pima Indians with type II diabetes and microalbuminuria. Diabetologia 1999;42:1341-1344
    • (1999) Diabetologia , vol.42 , pp. 1341-1344
    • Meyer, T.W.1    Bennett, P.H.2    Nelson, R.G.3
  • 21
    • 0037381607 scopus 로고    scopus 로고
    • Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes
    • Dalla Vestra M, Masiero A, Roiter AM, Saller A, Crepaldi G, Fioretto P. Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes. Diabetes 2003;52:1031-1035
    • (2003) Diabetes , vol.52 , pp. 1031-1035
    • Dalla Vestra, M.1    Masiero, A.2    Roiter, A.M.3    Saller, A.4    Crepaldi, G.5    Fioretto, P.6
  • 22
    • 0036433059 scopus 로고    scopus 로고
    • Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: Effects of angiotensin converting enzyme inhibition
    • Langham RG, Kelly DJ, Cox AJ, et al. Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition. Diabetologia 2002;45:1572- 1576
    • (2002) Diabetologia , vol.45 , pp. 1572-1576
    • Langham, R.G.1    Kelly, D.J.2    Cox, A.J.3
  • 23
    • 2542455650 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats
    • Hoffmann S, Podlich D, Hähnel B, Kriz W, Gretz N. Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats. J Am Soc Nephrol 2004;15:1475-1487
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1475-1487
    • Hoffmann, S.1    Podlich, D.2    Hähnel, B.3    Kriz, W.4    Gretz, N.5
  • 24
    • 84865569776 scopus 로고    scopus 로고
    • Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells
    • Zhang D, Chen Y, Xie X, et al. Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells. J Mol Cell Cardiol 2012;53:487-496
    • (2012) J Mol Cell Cardiol , vol.53 , pp. 487-496
    • Zhang, D.1    Chen, Y.2    Xie, X.3
  • 25
    • 84868628539 scopus 로고    scopus 로고
    • ENOS deficiency predisposes podocytes to injury in diabetes
    • Yuen DA, Stead BE, Zhang Y, et al. eNOS deficiency predisposes podocytes to injury in diabetes. J Am Soc Nephrol 2012;23:1810-1823
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1810-1823
    • Yuen, D.A.1    Stead, B.E.2    Zhang, Y.3
  • 26
    • 0035199084 scopus 로고    scopus 로고
    • Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism
    • Li B, Yao J, Morioka T, Oite T. Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism. J Am Soc Nephrol 2001;12:2616-2624
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2616-2624
    • Li, B.1    Yao, J.2    Morioka, T.3    Oite, T.4
  • 27
    • 84862756066 scopus 로고    scopus 로고
    • Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes
    • Slater SC, Ramnath RD, Uttridge K, et al. Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes. Int J Biochem Cell Biol 2012;44:1482-1490
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 1482-1490
    • Slater, S.C.1    Ramnath, R.D.2    Uttridge, K.3
  • 28
    • 77957861954 scopus 로고    scopus 로고
    • Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling
    • Sison K, Eremina V, Baelde H, et al. Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling. J Am Soc Nephrol 2010;21:1691-1701
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1691-1701
    • Sison, K.1    Eremina, V.2    Baelde, H.3
  • 29
    • 35448963479 scopus 로고    scopus 로고
    • Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions
    • Advani A, Kelly DJ, Advani SL, et al. Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions. Proc Natl Acad Sci U S A 2007;104:14448-14453
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 14448-14453
    • Advani, A.1    Kelly, D.J.2    Advani, S.L.3
  • 30
    • 40849130173 scopus 로고    scopus 로고
    • VEGF inhibition and renal thrombotic microangiopathy
    • Eremina V, Jefferson JA, Kowalewska J, et al. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 2008;358:1129-1136
    • (2008) N Engl J Med , vol.358 , pp. 1129-1136
    • Eremina, V.1    Jefferson, J.A.2    Kowalewska, J.3
  • 31
    • 0037370325 scopus 로고    scopus 로고
    • Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
    • Eremina V, Sood M, Haigh J, et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003;111:707-716
    • (2003) J Clin Invest , vol.111 , pp. 707-716
    • Eremina, V.1    Sood, M.2    Haigh, J.3
  • 32
    • 77955870854 scopus 로고    scopus 로고
    • Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease
    • Veron D, Reidy KJ, Bertuccio C, et al. Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease. Kidney Int 2010;77: 989-999
    • (2010) Kidney Int , vol.77 , pp. 989-999
    • Veron, D.1    Reidy, K.J.2    Bertuccio, C.3
  • 33
    • 0032712434 scopus 로고    scopus 로고
    • Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes
    • Cooper ME, Vranes D, Youssef S, et al. Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes. Diabetes 1999;48:2229-2239
    • (1999) Diabetes , vol.48 , pp. 2229-2239
    • Cooper, M.E.1    Vranes, D.2    Youssef, S.3
  • 34
    • 34249901258 scopus 로고    scopus 로고
    • Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy
    • Lindenmeyer MT, Kretzler M, Boucherot A, et al. Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy. J Am Soc Nephrol 2007;18:1765-1776
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1765-1776
    • Lindenmeyer, M.T.1    Kretzler, M.2    Boucherot, A.3
  • 35
    • 0035034655 scopus 로고    scopus 로고
    • Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes
    • de Vriese AS, Tilton RG, Elger M, Stephan CC, Kriz W, Lameire NH. Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J Am Soc Nephrol 2001;12: 993-1000
    • (2001) J Am Soc Nephrol , vol.12 , pp. 993-1000
    • De Vriese, A.S.1    Tilton, R.G.2    Elger, M.3    Stephan, C.C.4    Kriz, W.5    Lameire, N.H.6
  • 36
    • 33750713086 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice
    • Sung SH, Ziyadeh FN, Wang A, Pyagay PE, Kanwar YS, Chen S. Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice. J Am Soc Nephrol 2006;17:3093-3104
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3093-3104
    • Sung, S.H.1    Ziyadeh, F.N.2    Wang, A.3    Pyagay, P.E.4    Kanwar, Y.S.5    Chen, S.6
  • 37
    • 58149343883 scopus 로고    scopus 로고
    • Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice
    • Ku CH, White KE, Dei Cas A, et al. Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice. Diabetes 2008;57: 2824-2833
    • (2008) Diabetes , vol.57 , pp. 2824-2833
    • Ku, C.H.1    White, K.E.2    Dei Cas, A.3
  • 39
    • 68049123542 scopus 로고    scopus 로고
    • The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature
    • Takabatake Y, Sugiyama T, Kohara H, et al. The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature. J Am Soc Nephrol 2009;20:1714-1723
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1714-1723
    • Takabatake, Y.1    Sugiyama, T.2    Kohara, H.3
  • 40
    • 70349882090 scopus 로고    scopus 로고
    • Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes
    • Sayyed SG, Hägele H, Kulkarni OP, et al. Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes. Diabetologia 2009;52:2445-2454
    • (2009) Diabetologia , vol.52 , pp. 2445-2454
    • Sayyed, S.G.1    Hägele, H.2    Kulkarni, O.P.3
  • 41
    • 79957880117 scopus 로고    scopus 로고
    • Angiopoietin-1 is essential in mouse vasculature during development and in response to injury
    • Jeansson M, Gawlik A, Anderson G, et al. Angiopoietin-1 is essential in mouse vasculature during development and in response to injury. J Clin Invest 2011;121:2278-2289
    • (2011) J Clin Invest , vol.121 , pp. 2278-2289
    • Jeansson, M.1    Gawlik, A.2    Anderson, G.3
  • 42
    • 34547628176 scopus 로고    scopus 로고
    • Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia
    • Davis B, Dei Cas A, Long DA, et al. Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia. J Am Soc Nephrol 2007;18:2320-2329
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2320-2329
    • Davis, B.1    Dei Cas, A.2    Long, D.A.3
  • 43
    • 33947649573 scopus 로고    scopus 로고
    • Enhanced expression of ANGPTL2 in the microvascular lesions of diabetic glomerulopathy
    • Sun H, Zheng JM, Chen S, Zeng CH, Liu ZH, Li LS. Enhanced expression of ANGPTL2 in the microvascular lesions of diabetic glomerulopathy. Nephron, Exp Nephrol 2007;105:e117-e123
    • (2007) Nephron, Exp Nephrol , vol.105
    • Sun, H.1    Zheng, J.M.2    Chen, S.3    Zeng, C.H.4    Zh, L.5    Li, L.S.6
  • 44
    • 70450159783 scopus 로고    scopus 로고
    • Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development
    • Reidy KJ, Villegas G, Teichman J, et al. Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development. Development 2009;136:3979-3989
    • (2009) Development , vol.136 , pp. 3979-3989
    • Reidy, K.J.1    Villegas, G.2    Teichman, J.3
  • 45
    • 0036872716 scopus 로고    scopus 로고
    • Ontogeny of semaphorins 3A and 3F and their receptors neuropilins 1 and 2 in the kidney
    • Villegas G, Tufro A. Ontogeny of semaphorins 3A and 3F and their receptors neuropilins 1 and 2 in the kidney. Gene Expr Patterns 2002;2:151-155
    • (2002) Gene Expr Patterns , vol.2 , pp. 151-155
    • Villegas, G.1    Tufro, A.2
  • 46
    • 35948934636 scopus 로고    scopus 로고
    • Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis
    • Isermann B, Vinnikov IA, Madhusudhan T, et al. Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. Nat Med 2007;13:1349-1358
    • (2007) Nat Med , vol.13 , pp. 1349-1358
    • Isermann, B.1    Vinnikov, I.A.2    Madhusudhan, T.3
  • 47
    • 84872193981 scopus 로고    scopus 로고
    • Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc
    • Bock F, Shahzad K, Wang H, et al. Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc. Proc Natl Acad Sci U S A 2013;110:648-653
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 648-653
    • Bock, F.1    Shahzad, K.2    Wang, H.3
  • 48
    • 33745257029 scopus 로고    scopus 로고
    • Circulating activated protein C is reduced in young survivors of myocardial infarction and inversely correlates with the severity of coronary lesions
    • Zorio E, Navarro S, Medina P, et al. Circulating activated protein C is reduced in young survivors of myocardial infarction and inversely correlates with the severity of coronary lesions. J Thromb Haemost 2006;4:1530-1536
    • (2006) J Thromb Haemost , vol.4 , pp. 1530-1536
    • Zorio, E.1    Navarro, S.2    Medina, P.3
  • 49
    • 79960139810 scopus 로고    scopus 로고
    • WT1- dependent sulfatase expression maintains the normal glomerular filtration barrier
    • Schumacher VA, Schlötzer-Schrehardt U, Karumanchi SA, et al. WT1- dependent sulfatase expression maintains the normal glomerular filtration barrier. J Am Soc Nephrol 2011;22:1286-1296
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1286-1296
    • Schumacher, V.A.1    Schlötzer-Schrehardt, U.2    Karumanchi, S.A.3
  • 50
    • 33646501496 scopus 로고    scopus 로고
    • Local VEGF activity but not VEGF expression is tightly regulated during diabetic nephropathy in man
    • Hohenstein B, Hausknecht B, Boehmer K, Riess R, Brekken RA, Hugo CP. Local VEGF activity but not VEGF expression is tightly regulated during diabetic nephropathy in man. Kidney Int 2006;69:1654-1661
    • (2006) Kidney Int , vol.69 , pp. 1654-1661
    • Hohenstein, B.1    Hausknecht, B.2    Boehmer, K.3    Riess, R.4    Brekken, R.A.5    Hugo, C.P.6
  • 52
    • 33847682663 scopus 로고    scopus 로고
    • MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
    • Kato M, Zhang J, Wang M, et al. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A 2007;104:3432-3437
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3432-3437
    • Kato, M.1    Zhang, J.2    Wang, M.3
  • 53
    • 84866320598 scopus 로고    scopus 로고
    • How do microRNAs affect vascular smooth muscle cell biology?
    • Robinson HC, Baker AH. How do microRNAs affect vascular smooth muscle cell biology? Curr Opin Lipidol 2012;23:405-411
    • (2012) Curr Opin Lipidol , vol.23 , pp. 405-411
    • Robinson, H.C.1    Baker, A.H.2
  • 54
    • 0033848466 scopus 로고    scopus 로고
    • Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease
    • Tanji N, Markowitz GS, Fu C, et al. Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease. J Am Soc Nephrol 2000;11:1656-1666
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1656-1666
    • Tanji, N.1    Markowitz, G.S.2    Fu, C.3
  • 55
    • 70349149467 scopus 로고    scopus 로고
    • Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes
    • Tarabra E, Giunti S, Barutta F, et al. Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. Diabetes 2009;58:2109-2118
    • (2009) Diabetes , vol.58 , pp. 2109-2118
    • Tarabra, E.1    Giunti, S.2    Barutta, F.3
  • 56
    • 65549157823 scopus 로고    scopus 로고
    • Mechanisms of podocyte injury in diabetes: Role of cytochrome P450 and NADPH oxidases
    • Eid AA, Gorin Y, Fagg BM, et al. Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases. Diabetes 2009;58:1201-1211
    • (2009) Diabetes , vol.58 , pp. 1201-1211
    • Eid, A.A.1    Gorin, Y.2    Fagg, B.M.3
  • 57
    • 84872047522 scopus 로고    scopus 로고
    • Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli
    • Hodgin JB, Nair V, Zhang H, et al. Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli. Diabetes 2013;62:299-308
    • (2013) Diabetes , vol.62 , pp. 299-308
    • Hodgin, J.B.1    Nair, V.2    Zhang, H.3
  • 58
    • 43049095682 scopus 로고    scopus 로고
    • Adiponectin regulates albuminuria and podocyte function in mice
    • Sharma K, Ramachandrarao S, Qiu G, et al. Adiponectin regulates albuminuria and podocyte function in mice. J Clin Invest 2008;118:1645-1656
    • (2008) J Clin Invest , vol.118 , pp. 1645-1656
    • Sharma, K.1    Ramachandrarao, S.2    Qiu, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.