-
1
-
-
78650796942
-
Role of PPARα and its agonist in renal diseases
-
345098
-
Cheng CF, Chen HH, Lin H. Role of PPARα and its agonist in renal diseases. PPAR Res 2010;2010:345098.
-
(2010)
PPAR Res 2010
-
-
Cheng, C.F.1
Chen, H.H.2
Lin, H.3
-
2
-
-
77954987061
-
PPARalpha: energy combustion, hypolipidemia, inflammation and cancer
-
Pyper SR, Viswakarma N, Yu S, Reddy JK. PPARalpha: energy combustion, hypolipidemia, inflammation and cancer. Nucl Recept Signal 2010;8:e002.
-
(2010)
Nucl Recept Signal
, vol.8
-
-
Pyper, S.R.1
Viswakarma, N.2
Yu, S.3
Reddy, J.K.4
-
4
-
-
33747154772
-
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
-
Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 2006;126: 789-99.
-
(2006)
Cell
, vol.126
, pp. 789-799
-
-
Bookout, A.L.1
Jeong, Y.2
Downes, M.3
Yu, R.T.4
Evans, R.M.5
Mangelsdorf, D.J.6
-
5
-
-
0035658541
-
Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature
-
Guan Y, Zhang Y, Schneider A, Davis L, Breyer RM, Breyer MD. Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. Am J Physiol Renal Physiol 2001;281:F1036-46.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Guan, Y.1
Zhang, Y.2
Schneider, A.3
Davis, L.4
Breyer, R.M.5
Breyer, M.D.6
-
6
-
-
0031408955
-
Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans
-
Guan Y, Zhang Y, Davis L, Breyer MD. Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans. Am J Physiol 1997;273(6 Pt 2):F1013-22.
-
(1997)
Am J Physiol
, vol.273
, Issue.6 PART 2
-
-
Guan, Y.1
Zhang, Y.2
Davis, L.3
Breyer, M.D.4
-
7
-
-
0037369871
-
PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by acti vating the ABCA1 cholesterol efflux pathway
-
Ruan XZ, Moorhead JF, Fernando R, Wheeler DC, Powis SH, Varghese Z. PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by acti vating the ABCA1 cholesterol efflux pathway. J Am Soc Nephrol 2003;14:593-600.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 593-600
-
-
Ruan, X.Z.1
Moorhead, J.F.2
Fernando, R.3
Wheeler, D.C.4
Powis, S.H.5
Varghese, Z.6
-
10
-
-
0346003777
-
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression
-
Yu S, Matsusue K, Kashireddy P, Cao WQ, Yeldandi V, Yeldandi AV, Rao MS, Gonzalez FJ, Reddy JK. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem 2003;278:498-505.
-
(2003)
J Biol Chem
, vol.278
, pp. 498-505
-
-
Yu, S.1
Matsusue, K.2
Kashireddy, P.3
Cao, W.Q.4
Yeldandi, V.5
Yeldandi, A.V.6
Rao, M.S.7
Gonzalez, F.J.8
Reddy, J.K.9
-
12
-
-
27944442216
-
Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure
-
Letavernier E, Perez J, Joye E, Bellocq A, Fouqueray B, Haymann JP, Heudes D, Wahli W, Desvergne B, Baud L. Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure. J Am Soc Nephrol 2005;16:2395-402.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2395-2402
-
-
Letavernier, E.1
Perez, J.2
Joye, E.3
Bellocq, A.4
Fouqueray, B.5
Haymann, J.P.6
Heudes, D.7
Wahli, W.8
Desvergne, B.9
Baud, L.10
-
13
-
-
16644377741
-
Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome
-
Guan Y. Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome. J Am Soc Nephrol 2004;15:2801-15.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2801-2815
-
-
Guan, Y.1
-
14
-
-
67449108376
-
Peroxisome proliferator-activated receptor-alpha (PPARalpha): at the crossroads of obesity, diabetes and cardiovascular disease
-
Fruchart JC. Peroxisome proliferator-activated receptor-alpha (PPARalpha): at the crossroads of obesity, diabetes and cardiovascular disease. Atherosclerosis 2009;205:1-8.
-
(2009)
Atherosclerosis
, vol.205
, pp. 1-8
-
-
Fruchart, J.C.1
-
15
-
-
0033305213
-
Peroxisome proliferator-activated receptors: nuclear control of metabolism
-
Desvergne B, Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999;20: 649-88.
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
16
-
-
0035923672
-
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
-
Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A 2001;98:13919-24.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13919-13924
-
-
Xu, H.E.1
Lambert, M.H.2
Montana, V.G.3
Plunket, K.D.4
Moore, L.B.5
Collins, J.L.6
Oplinger, J.A.7
Kliewer, S.A.8
Gampe Jr., R.T.9
McKee, D.D.10
Moore, J.T.11
Willson, T.M.12
-
17
-
-
0036013438
-
Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element
-
Pineda Torra I, Jamshidi Y, Flavell DM, Fruchart JC, Staels B. Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element. Mol Endocrinol 2002;16:1013-28.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1013-1028
-
-
Pineda Torra, I.1
Jamshidi, Y.2
Flavell, D.M.3
Fruchart, J.C.4
Staels, B.5
-
18
-
-
44149085369
-
PPARalpha gene expression is up-regulated by LXR and PXR activators in the small intestine
-
Inoue J, Satoh S, Kita M, Nakahara M, Hachimura S, Miyata M, Nishimaki-Mogami T, Sato R. PPARalpha gene expression is up-regulated by LXR and PXR activators in the small intestine. Biochem Biophys Res Commun 2008;371:675-8.
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 675-678
-
-
Inoue, J.1
Satoh, S.2
Kita, M.3
Nakahara, M.4
Hachimura, S.5
Miyata, M.6
Nishimaki-Mogami, T.7
Sato, R.8
-
19
-
-
0032484123
-
Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging
-
Poynter ME, Daynes RA. Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem 1998;273: 32833-41.
-
(1998)
J Biol Chem
, vol.273
, pp. 32833-32841
-
-
Poynter, M.E.1
Daynes, R.A.2
-
20
-
-
0034034671
-
Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators
-
Corton JC, Anderson SP, Stauber A. Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators. Annu Rev Pharmacol Toxicol 2000;40:491-518.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 491-518
-
-
Corton, J.C.1
Anderson, S.P.2
Stauber, A.3
-
21
-
-
44849141405
-
Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men
-
Rigamonti E, Chinetti-Gbaguidi G, Staels B. Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men. Arterioscler Thromb Vasc Biol 2008; 28:1050-9.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1050-1059
-
-
Rigamonti, E.1
Chinetti-Gbaguidi, G.2
Staels, B.3
-
22
-
-
45749154831
-
Multiple interactions between peroxisome proliferators-activated receptors and the ubiquitin-proteasome system and implications for cancer pathogenesis
-
195065
-
Genini D, Carbone GM, Catapano CV. Multiple interactions between peroxisome proliferators-activated receptors and the ubiquitin-proteasome system and implications for cancer pathogenesis. PPAR Res 2008;2008:195065.
-
(2008)
PPAR Res 2008
-
-
Genini, D.1
Carbone, G.M.2
Catapano, C.V.3
-
23
-
-
56749130032
-
Structure of the intact PPAR-gamma-RXR-nuclear receptor complex on DNA
-
Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F. Structure of the intact PPAR-gamma-RXR-nuclear receptor complex on DNA. Nature 2008;456:350-6.
-
(2008)
Nature
, vol.456
, pp. 350-356
-
-
Chandra, V.1
Huang, P.2
Hamuro, Y.3
Raghuram, S.4
Wang, Y.5
Burris, T.P.6
Rastinejad, F.7
-
24
-
-
77953246434
-
Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis
-
van der Meer DL, Degenhardt T, Vaisanen S, de Groot PJ, Heinaniemi M, de Vries SC, Muller M, Carlberg C, Kersten S. Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis. Nucleic Acids Res 2010; 38:2839-50.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 2839-2850
-
-
van der Meer, D.L.1
Degenhardt, T.2
Vaisanen, S.3
de Groot, P.J.4
Heinaniemi, M.5
de Vries, S.C.6
Muller, M.7
Carlberg, C.8
Kersten, S.9
-
25
-
-
0030771852
-
DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements Importance of the 5'-flanking region
-
Juge-Aubry C, Pernin A, Favez T, Burger AG, Wahli W, Meier CA, Desvergne B. DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5'-flanking region. J Biol Chem 1997;272:25252-9.
-
(1997)
J Biol Chem
, vol.272
, pp. 25252-25259
-
-
Juge-Aubry, C.1
Pernin, A.2
Favez, T.3
Burger, A.G.4
Wahli, W.5
Meier, C.A.6
Desvergne, B.7
-
26
-
-
0030341454
-
Cloning and identification of mouse steroid receptor coactivator-1 (mSRC- 1), as a coactivator of peroxisome proliferator-activated receptor gamma
-
Zhu Y, Qi C, Calandra C, Rao MS, Reddy JK. Cloning and identification of mouse steroid receptor coactivator-1 (mSRC- 1), as a coactivator of peroxisome proliferator-activated receptor gamma. Gene Expr 1996;6:185-95.
-
(1996)
Gene Expr
, vol.6
, pp. 185-195
-
-
Zhu, Y.1
Qi, C.2
Calandra, C.3
Rao, M.S.4
Reddy, J.K.5
-
27
-
-
0033018148
-
Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein
-
Dowell P, Ishmael JE, Avram D, Peterson VJ, Nevrivy DJ, Leid M. Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein. J Biol Chem 1999;274:15901-7.
-
(1999)
J Biol Chem
, vol.274
, pp. 15901-15907
-
-
Dowell, P.1
Ishmael, J.E.2
Avram, D.3
Peterson, V.J.4
Nevrivy, D.J.5
Leid, M.6
-
28
-
-
32644460092
-
From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
-
Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W. From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 2006;45:120-59.
-
(2006)
Prog Lipid Res
, vol.45
, pp. 120-159
-
-
Feige, J.N.1
Gelman, L.2
Michalik, L.3
Desvergne, B.4
Wahli, W.5
-
29
-
-
0035977050
-
p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response
-
Barger PM, Browning AC, Garner AN, Kelly DP. p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response. J Biol Chem 2001;276:44495-501.
-
(2001)
J Biol Chem
, vol.276
, pp. 44495-44501
-
-
Barger, P.M.1
Browning, A.C.2
Garner, A.N.3
Kelly, D.P.4
-
30
-
-
34547589477
-
Modulation of PPAR activity via phosphorylation
-
Burns KA, Vanden Heuvel JP. Modulation of PPAR activity via phosphorylation. Biochim Biophys Acta 2007;1771:952-60.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 952-960
-
-
Burns, K.A.1
Vanden Heuvel, J.P.2
-
31
-
-
3442877840
-
The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha
-
Blanquart C, Mansouri R, Paumelle R, Fruchart JC, Staels B, Glineur C. The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha. Mol Endocrinol 2004;18:1906-18.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 1906-1918
-
-
Blanquart, C.1
Mansouri, R.2
Paumelle, R.3
Fruchart, J.C.4
Staels, B.5
Glineur, C.6
-
32
-
-
1042286477
-
Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis
-
Ricote M, Valledor AF, Glass CK. Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis. Arterioscler Thromb Vasc Biol 2004;24:230-9.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 230-239
-
-
Ricote, M.1
Valledor, A.F.2
Glass, C.K.3
-
33
-
-
70349984006
-
Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats
-
Shin SJ, Lim JH, Chung S, Youn DY, Chung HW, Kim HW, Lee JH, Chang YS, Park CW. Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats. Hypertens Res 2009;32:835-45.
-
(2009)
Hypertens Res
, vol.32
, pp. 835-845
-
-
Shin, S.J.1
Lim, J.H.2
Chung, S.3
Youn, D.Y.4
Chung, H.W.5
Kim, H.W.6
Lee, J.H.7
Chang, Y.S.8
Park, C.W.9
-
34
-
-
70349980886
-
Prevention of local lipotoxicity: a new renoprotective mechanism of peroxisome proliferator-activated receptor-alpha activation in hypertension and obesity?
-
Zhao X. Prevention of local lipotoxicity: a new renoprotective mechanism of peroxisome proliferator-activated receptor-alpha activation in hypertension and obesity? Hypertens Res 2009;32:821-3.
-
(2009)
Hypertens Res
, vol.32
, pp. 821-823
-
-
Zhao, X.1
-
35
-
-
0029661982
-
The PPARalpha-leukotriene B4 pathway to inflammation control
-
Devchand PR, Keller H, Peters JM, Vazquez M, Gonzalez FJ, Wahli W. The PPARalpha-leukotriene B4 pathway to inflammation control. Nature 1996;384:39-43.
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
Vazquez, M.4
Gonzalez, F.J.5
Wahli, W.6
-
36
-
-
34547597709
-
PPARalpha in atherosclerosis and inflammation
-
Zandbergen F, Plutzky J. PPARalpha in atherosclerosis and inflammation. Biochim Biophys Acta 2007;1771:972-82.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 972-982
-
-
Zandbergen, F.1
Plutzky, J.2
-
38
-
-
2242436246
-
Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice
-
Duez H, Chao YS, Hernandez M, Torpier G, Poulain P, Mundt S, Mallat Z, Teissier E, Burton CA, Tedgui A, Fruchart JC, Fievet C, Wright SD, Staels B. Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice. J Biol Chem 2002;277:48051-7.
-
(2002)
J Biol Chem
, vol.277
, pp. 48051-48057
-
-
Duez, H.1
Chao, Y.S.2
Hernandez, M.3
Torpier, G.4
Poulain, P.5
Mundt, S.6
Mallat, Z.7
Teissier, E.8
Burton, C.A.9
Tedgui, A.10
Fruchart, J.C.11
Fievet, C.12
Wright, S.D.13
Staels, B.14
-
39
-
-
56349166510
-
PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways
-
Ramanan S, Kooshki M, Zhao W, Hsu FC, Robbins ME. PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways. Free Radic Biol Med 2008;45:1695-704.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1695-1704
-
-
Ramanan, S.1
Kooshki, M.2
Zhao, W.3
Hsu, F.C.4
Robbins, M.E.5
-
40
-
-
0037195465
-
PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4
-
Kintscher U, Lyon C, Wakino S, Bruemmer D, Feng X, Goetze S, Graf K, Moustakas A, Staels B, Fleck E, Hsueh WA, Law RE. PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4. Circ Res 2002;91:e35-44.
-
(2002)
Circ Res
, vol.91
-
-
Kintscher, U.1
Lyon, C.2
Wakino, S.3
Bruemmer, D.4
Feng, X.5
Goetze, S.6
Graf, K.7
Moustakas, A.8
Staels, B.9
Fleck, E.10
Hsueh, W.A.11
Law, R.E.12
-
41
-
-
0036882119
-
PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation
-
Diep QN, Amiri F, Touyz RM, Cohn JS, Endemann D, Neves MF, Schiffrin EL. PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension 2002;40:866-71.
-
(2002)
Hypertension
, vol.40
, pp. 866-871
-
-
Diep, Q.N.1
Amiri, F.2
Touyz, R.M.3
Cohn, J.S.4
Endemann, D.5
Neves, M.F.6
Schiffrin, E.L.7
-
42
-
-
0035942194
-
Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension
-
Holla VR, Adas F, Imig JD, Zhao X, Price E Jr, Olsen N, Kovacs WJ, Magnuson MA, Keeney DS, Breyer MD, Falck JR, Waterman MR, Capdevila JH. Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. Proc Natl Acad Sci U S A 2001;98:5211-6.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5211-5216
-
-
Holla, V.R.1
Adas, F.2
Imig, J.D.3
Zhao, X.4
Price Jr., E.5
Olsen, N.6
Kovacs, W.J.7
Magnuson, M.A.8
Keeney, D.S.9
Breyer, M.D.10
Falck, J.R.11
Waterman, M.R.12
Capdevila, J.H.13
-
43
-
-
75649145898
-
Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive rats
-
Chung S, Park CW, Shin SJ, Lim JH, Chung HW, Youn DY, Kim HW, Kim BS, Lee JH, Kim GH, Chang YS. Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive rats. Nephrol Dial Transplant 2010;25:389-99.
-
(2010)
Nephrol Dial Transplant
, vol.25
, pp. 389-399
-
-
Chung, S.1
Park, C.W.2
Shin, S.J.3
Lim, J.H.4
Chung, H.W.5
Youn, D.Y.6
Kim, H.W.7
Kim, B.S.8
Lee, J.H.9
Kim, G.H.10
Chang, Y.S.11
-
45
-
-
1542707159
-
Phenotype of peroxisome proliferator-activated receptor-alpha(PPARalpha)deficient mice on mixed background fed high fat diet
-
Kim BH, Won YS, Kim EY, Yoon M, Nam KT, Oh GT, Kim DY. Phenotype of peroxisome proliferator-activated receptor-alpha(PPARalpha)deficient mice on mixed background fed high fat diet. J Vet Sci 2003;4:239-44.
-
(2003)
J Vet Sci
, vol.4
, pp. 239-244
-
-
Kim, B.H.1
Won, Y.S.2
Kim, E.Y.3
Yoon, M.4
Nam, K.T.5
Oh, G.T.6
Kim, D.Y.7
-
46
-
-
0036352058
-
Cardiac function and metabolism in type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator
-
Aasum E, Belke DD, Severson DL, Riemersma RA, Cooper M, Andreassen M, Larsen TS. Cardiac function and metabolism in type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator. Am J Physiol Heart Circ Physiol 2002;283:H949-57.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Aasum, E.1
Belke, D.D.2
Severson, D.L.3
Riemersma, R.A.4
Cooper, M.5
Andreassen, M.6
Larsen, T.S.7
-
47
-
-
0042822095
-
Peroxisome proliferator-activated receptor (PPAR)- alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation
-
Koh EH, Kim MS, Park JY, Kim HS, Youn JY, Park HS, Youn JH, Lee KU. Peroxisome proliferator-activated receptor (PPAR)- alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation. Diabetes 2003;52:2331-7.
-
(2003)
Diabetes
, vol.52
, pp. 2331-2337
-
-
Koh, E.H.1
Kim, M.S.2
Park, J.Y.3
Kim, H.S.4
Youn, J.Y.5
Park, H.S.6
Youn, J.H.7
Lee, K.U.8
-
48
-
-
33646508121
-
PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice
-
Park CW, Zhang Y, Zhang X, Wu J, Chen L, Cha DR, Su D, Hwang MT, Fan X, Davis L, Striker G, Zheng F, Breyer M, Guan Y. PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int 2006;69:1511-7.
-
(2006)
Kidney Int
, vol.69
, pp. 1511-1517
-
-
Park, C.W.1
Zhang, Y.2
Zhang, X.3
Wu, J.4
Chen, L.5
Cha, D.R.6
Su, D.7
Hwang, M.T.8
Fan, X.9
Davis, L.10
Striker, G.11
Zheng, F.12
Breyer, M.13
Guan, Y.14
-
49
-
-
33745313224
-
Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha
-
Park CW, Kim HW, Ko SH, Chung HW, Lim SW, Yang CW, Chang YS, Sugawara A, Guan Y, Breyer MD. Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha. Diabetes 2006;55:885-93.
-
(2006)
Diabetes
, vol.55
, pp. 885-893
-
-
Park, C.W.1
Kim, H.W.2
Ko, S.H.3
Chung, H.W.4
Lim, S.W.5
Yang, C.W.6
Chang, Y.S.7
Sugawara, A.8
Guan, Y.9
Breyer, M.D.10
-
50
-
-
34047205064
-
Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice
-
Park CW, Kim HW, Ko SH, Lim JH, Ryu GR, Chung HW, Han SW, Shin SJ, Bang BK, Breyer MD, Chang YS. Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice. J Am Soc Nephrol 2007;18:1227-38.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1227-1238
-
-
Park, C.W.1
Kim, H.W.2
Ko, S.H.3
Lim, J.H.4
Ryu, G.R.5
Chung, H.W.6
Han, S.W.7
Shin, S.J.8
Bang, B.K.9
Breyer, M.D.10
Chang, Y.S.11
-
51
-
-
0036287662
-
Identification of functions of peroxisome proliferator-activated receptor alpha in proximal tubules
-
Kamijo Y, Hora K, Tanaka N, Usuda N, Kiyosawa K, Nakajima T, Gonzalez FJ, Aoyama T. Identification of functions of peroxisome proliferator-activated receptor alpha in proximal tubules. J Am Soc Nephrol 2002;13:1691-702.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1691-1702
-
-
Kamijo, Y.1
Hora, K.2
Tanaka, N.3
Usuda, N.4
Kiyosawa, K.5
Nakajima, T.6
Gonzalez, F.J.7
Aoyama, T.8
-
52
-
-
0036941407
-
PPAR-alpha ligands inhibit H2O2-mediated activation of transforming growth factor-beta1 in human mesangial cells
-
Wilmer WA, Dixon CL, Hebert C, Lu L, Rovin BH. PPAR-alpha ligands inhibit H2O2-mediated activation of transforming growth factor-beta1 in human mesangial cells. Antioxid Redox Signal 2002;4:877-84.
-
(2002)
Antioxid Redox Signal
, vol.4
, pp. 877-884
-
-
Wilmer, W.A.1
Dixon, C.L.2
Hebert, C.3
Lu, L.4
Rovin, B.H.5
-
53
-
-
79953862219
-
Long-term blockade of vascular endothelial growth factor receptor-2 aggravates the diabetic renal dysfunction associated with inactivation of the Akt/eNOS-NO axis
-
Kim HW, Lim JH, Kim MY, Chung S, Shin SJ, Chung HW, Choi BS, Kim YS, Chang YS, Park CW. Long-term blockade of vascular endothelial growth factor receptor-2 aggravates the diabetic renal dysfunction associated with inactivation of the Akt/eNOS-NO axis. Nephrol Dial Transplant 2011;26:1173-88.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 1173-1188
-
-
Kim, H.W.1
Lim, J.H.2
Kim, M.Y.3
Chung, S.4
Shin, S.J.5
Chung, H.W.6
Choi, B.S.7
Kim, Y.S.8
Chang, Y.S.9
Park, C.W.10
-
54
-
-
70350528625
-
Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice
-
Park CW, Kim HW, Lim JH, Yoo KD, Chung S, Shin SJ, Chung HW, Lee SJ, Chae CB, Kim YS, Chang YS. Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice. Diabetes 2009;58:2666-76.
-
(2009)
Diabetes
, vol.58
, pp. 2666-2676
-
-
Park, C.W.1
Kim, H.W.2
Lim, J.H.3
Yoo, K.D.4
Chung, S.5
Shin, S.J.6
Chung, H.W.7
Lee, S.J.8
Chae, C.B.9
Kim, Y.S.10
Chang, Y.S.11
-
55
-
-
49749090062
-
Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth
-
Grau R, Diaz-Munoz MD, Cacheiro-Llaguno C, Fresno M, Iniguez MA. Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth. PPAR Res 2008;2008:352437.
-
(2008)
PPAR Res
, vol.2008
, pp. 352437
-
-
Grau, R.1
Diaz-Munoz, M.D.2
Cacheiro-Llaguno, C.3
Fresno, M.4
Iniguez, M.A.5
-
56
-
-
79953240855
-
Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis
-
Tanaka Y, Kume S, Araki S, Isshiki K, Chin-Kanasaki M, Sakaguchi M, Sugimoto T, Koya D, Heneda M, Kashiwagi A, Maegawa H, Uzu T. Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis. Kidney Int 2011;79:871-82.
-
(2011)
Kidney Int
, vol.79
, pp. 871-882
-
-
Tanaka, Y.1
Kume, S.2
Araki, S.3
Isshiki, K.4
Chin-Kanasaki, M.5
Sakaguchi, M.6
Sugimoto, T.7
Koya, D.8
Heneda, M.9
Kashiwagi, A.10
Maegawa, H.11
Uzu, T.12
-
57
-
-
0035166933
-
Effect of lipid reduction on the progression of renal disease: a meta-analysis
-
Fried LF, Orchard TJ, Kasiske BL. Effect of lipid reduction on the progression of renal disease: a meta-analysis. Kidney Int 2001;59:260-9.
-
(2001)
Kidney Int
, vol.59
, pp. 260-269
-
-
Fried, L.F.1
Orchard, T.J.2
Kasiske, B.L.3
-
58
-
-
0031437734
-
Can reduction in hypertriglyceridaemia slow progression of microalbuminuria in patients with non-insulin-dependent diabetes mellitus?
-
Smulders YM, van Eeden AE, Stehouwer CD, Weijers RN, Slaats EH, Silberbusch J. Can reduction in hypertriglyceridaemia slow progression of microalbuminuria in patients with non-insulin-dependent diabetes mellitus? Eur J Clin Invest 1997;27:997-1002.
-
(1997)
Eur J Clin Invest
, vol.27
, pp. 997-1002
-
-
Smulders, Y.M.1
van Eeden, A.E.2
Stehouwer, C.D.3
Weijers, R.N.4
Slaats, E.H.5
Silberbusch, J.6
-
59
-
-
28044452217
-
FIELD study investigators Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial
-
Keech A, Simes RJ, Barter P, Best J, Scott R, Taskinen MR, Forder P, Pillai A, Davis T, Glasziou P, Drury P, Kesaniemi YA, Sullivan D, Hunt D, Colman P, d'Emden M, Whiting M, Ehnholm C, Laakso M; FIELD study investigators. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 2005;366:1849-61.
-
(2005)
Lancet
, vol.366
, pp. 1849-1861
-
-
Keech, A.1
Simes, R.J.2
Barter, P.3
Best, J.4
Scott, R.5
Taskinen, M.R.6
Forder, P.7
Pillai, A.8
Davis, T.9
Glasziou, P.10
Drury, P.11
Kesaniemi, Y.A.12
Sullivan, D.13
Hunt, D.14
Colman, P.15
d'Emden, M.16
Whiting, M.17
Ehnholm, C.18
Laakso, M.19
-
60
-
-
77955585592
-
ACCORD trial group Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial
-
Ismail-Beigi F, Craven T, Banerji MA, Basile J, Calles J, Cohen RM, Cuddihy R, Cushman WC, Genuth S, Grimm RH Jr, Hamilton BP, Hoogwerf B, Karl D, Katz L, Krikorian A, O'Connor P, Pop-Busui R, Schubart U, Simmons D, Taylor H, Thomas A, Weiss D, Hramiak I; ACCORD trial group. Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet 2010;376:419-30.
-
(2010)
Lancet
, vol.376
, pp. 419-430
-
-
Ismail-Beigi, F.1
Craven, T.2
Banerji, M.A.3
Basile, J.4
Calles, J.5
Cohen, R.M.6
Cuddihy, R.7
Cushman, W.C.8
Genuth, S.9
Grimm Jr., R.H.10
Hamilton, B.P.11
Hoogwerf, B.12
Karl, D.13
Katz, L.14
Krikorian, A.15
O'Connor, P.16
Pop-Busui, R.17
Schubart, U.18
Simmons, D.19
Taylor, H.20
Thomas, A.21
Weiss, D.22
Hramiak, I.23
more..
-
61
-
-
77951704587
-
Effects of combination lipid therapy in type 2 diabetes mellitus
-
Accord Study Group
-
ACCORD Study Group, Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein HC, Probstfield J, Grimm RH, Ismail-Beigi F, Bigger JT, Goff DC Jr, Cushman WC, Simons-Morton DG, Byington RP. Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med 2010;362:1563-74.
-
(2010)
N Engl J Med
, vol.362
, pp. 1563-1574
-
-
Ginsberg, H.N.1
Elam, M.B.2
Lovato, L.C.3
Crouse III, J.R.4
Leiter, L.A.5
Linz, P.6
Friedewald, W.T.7
Buse, J.B.8
Gerstein, H.C.9
Probstfield, J.10
Grimm, R.H.11
Ismail-Beigi, F.12
Bigger, J.T.13
Goff Jr., D.C.14
Cushman, W.C.15
Simons-Morton, D.G.16
Byington, R.P.17
-
62
-
-
34548379454
-
Management of dyslipidemias in patients with diabetes and chronic kidney disease
-
Molitch ME. Management of dyslipidemias in patients with diabetes and chronic kidney disease. Clin J Am Soc Nephrol 2006;1:1090-9.
-
(2006)
Clin J Am Soc Nephrol
, vol.1
, pp. 1090-1099
-
-
Molitch, M.E.1
-
63
-
-
79951774866
-
Lipids, lipid-lowering therapy and diabetes complications
-
Valensi P, Picard S. Lipids, lipid-lowering therapy and diabetes complications. Diabetes Metab 2011;37:15-24.
-
(2011)
Diabetes Metab
, vol.37
, pp. 15-24
-
-
Valensi, P.1
Picard, S.2
-
64
-
-
0037417725
-
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content
-
Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP. A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proc Natl Acad Sci U S A 2003;100:1226-31.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1226-1231
-
-
Finck, B.N.1
Han, X.2
Courtois, M.3
Aimond, F.4
Nerbonne, J.M.5
Kovacs, A.6
Gross, R.W.7
Kelly, D.P.8
|