Co-delivery of paclitaxel and α-tocopherol succinate by novel chitosan-based polymeric micelles for improving micellar stability and efficacious combination therapy

Drug Development and Industrial Pharmacy

Volumn 41, Issue 7, 2015, Pages 1137-1147

  Emami, Jaber ^a   Rezazadeh, Mahboubeh ^a   Rostami, Mahboubeh ^a   Hassanzadeh, Farshid ^a   Sadeghi, Hojjat ^a   Mostafavi, Abolfazl ^a   Minaiyan, Mohsen ^a   Lavasanifar, Afsaneh ^b  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

controlled drug release; paclitaxel; synergistic chemotherapy; tocopherol succinate

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; CHITOSAN; OLIGOSACCHARIDE; PACLITAXEL; POLYMER; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; DRUG CARRIER; DRUG COMBINATION; MICELLE;

ARTICLE; CANCER CELL; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EXPOSURE; DRUG RELEASE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; HYDROPHOBICITY; IC50; IN VITRO STUDY; MICELLE; OVARIAN CANCER CELL LINE; PARTICLE SIZE; ZETA POTENTIAL; CHEMICAL PHENOMENA; CHEMISTRY; COMPARATIVE STUDY; DRUG COMBINATION; DRUG STABILITY; OVARIAN NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ALPHA-TOCOPHEROL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE, TUMOR; CHITOSAN; DRUG CARRIERS; DRUG COMBINATIONS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FEMALE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICELLES; OLIGOSACCHARIDES; OVARIAN NEOPLASMS; PACLITAXEL; PARTICLE SIZE;

EID: 84932635090     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2014.935390     Document Type: Article

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