메뉴 건너뛰기




Volumn 128, Issue 12, 2015, Pages 2302-2313

GABAB receptor promotes its own surface expression by recruiting a Rap1-dependent signaling cascade

Author keywords

GABAB receptor; Internalization; Protein protein interaction; Rap1; Recycling

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; GLUTATHIONE TRANSFERASE; GUANOSINE TRIPHOSPHATASE; RAP1 PROTEIN;

EID: 84932136451     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.167056     Document Type: Article
Times cited : (18)

References (59)
  • 1
    • 84862993893 scopus 로고    scopus 로고
    • GABAB receptor subunit GB1 at the cell surface independently activates ERK1/2 through IGF-1R transactivation
    • Baloucoune, G.A., Chun, L., Zhang, W., Xu, C., Huang, S., Sun, Q., Wang, Y., Tu, H. and Liu, J. (2012). GABAB receptor subunit GB1 at the cell surface independently activates ERK1/2 through IGF-1R transactivation. PLoS ONE 7, e39698.
    • (2012) PLoS ONE , vol.7
    • Baloucoune, G.A.1    Chun, L.2    Zhang, W.3    Xu, C.4    Huang, S.5    Sun, Q.6    Wang, Y.7    Tu, H.8    Liu, J.9
  • 2
    • 77955029173 scopus 로고    scopus 로고
    • Mechanisms of GABAB receptor exocytosis, endocytosis, and degradation
    • Benke, D. (2010). Mechanisms of GABAB receptor exocytosis, endocytosis, and degradation. Adv. Pharmacol. 58, 93-111.
    • (2010) Adv. Pharmacol , vol.58 , pp. 93-111
    • Benke, D.1
  • 5
    • 3042546515 scopus 로고    scopus 로고
    • Molecular structure and physiological functions of GABAB receptors
    • Bettler, B., Kaupmann, K., Mosbacher, J. and Gassmann, M. (2004). Molecular structure and physiological functions of GABAB receptors. Physiol. Rev. 84, 835-867.
    • (2004) Physiol. Rev , vol.84 , pp. 835-867
    • Bettler, B.1    Kaupmann, K.2    Mosbacher, J.3    Gassmann, M.4
  • 7
    • 3142685557 scopus 로고    scopus 로고
    • The heptahelical domain of GABAB2 is activated directly by CGP7930, a positive allosteric modulator of the GABAB receptor
    • Binet, V., Brajon, C., Le Corre, L., Acher, F., Pin, J.-P. and Prezeau, L. (2004). The heptahelical domain of GABAB2 is activated directly by CGP7930, a positive allosteric modulator of the GABAB receptor. J. Biol. Chem. 279, 29085-29091.
    • (2004) J. Biol. Chem , vol.279 , pp. 29085-29091
    • Binet, V.1    Brajon, C.2    Le Corre, L.3    Acher, F.4    Pin, J.-P.5    Prezeau, L.6
  • 9
    • 28644432057 scopus 로고    scopus 로고
    • Assemblydependent surface targeting of the heterodimeric GABAB Receptor is controlled by COPI but not 14-3-3
    • Brock, C., Boudier, L., Maurel, D., Blahos, J. and Pin, J.-P. (2005). Assemblydependent surface targeting of the heterodimeric GABAB Receptor is controlled by COPI but not 14-3-3. Mol. Biol. Cell 16, 5572-5578.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5572-5578
    • Brock, C.1    Boudier, L.2    Maurel, D.3    Blahos, J.4    Pin, J.-P.5
  • 11
    • 0030859482 scopus 로고    scopus 로고
    • Delta and kappa opioid receptors are differentially regulated by dynamin-dependent endocytosis when activated by the same alkaloid agonist
    • Chu, P., Murray, S., Lissin, D. and von Zastrow, M. (1997). Delta and kappa opioid receptors are differentially regulated by dynamin-dependent endocytosis when activated by the same alkaloid agonist. J. Biol. Chem. 272, 27124-27130.
    • (1997) J. Biol. Chem , vol.272 , pp. 27124-27130
    • Chu, P.1    Murray, S.2    Lissin, D.3    von Zastrow, M.4
  • 12
    • 0033626427 scopus 로고    scopus 로고
    • GABAB receptors: a new paradigm in G protein signaling
    • Couve, A., Moss, S. J. and Pangalos, M. N. (2000). GABAB receptors: a new paradigm in G protein signaling. Mol. Cell Neurosci. 16, 296-312.
    • (2000) Mol. Cell Neurosci , vol.16 , pp. 296-312
    • Couve, A.1    Moss, S.J.2    Pangalos, M.N.3
  • 15
    • 1842424991 scopus 로고    scopus 로고
    • Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability
    • Fairfax, B. P., Pitcher, J. A., Scott, M. G. H., Calver, A. R., Pangalos, M. N., Moss, S. J. and Couve, A. (2004). Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability. J. Biol. Chem. 279, 12565-12573.
    • (2004) J. Biol. Chem , vol.279 , pp. 12565-12573
    • Fairfax, B.P.1    Pitcher, J.A.2    Scott, M.G.H.3    Calver, A.R.4    Pangalos, M.N.5    Moss, S.J.6    Couve, A.7
  • 16
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
    • Ferguson, S. S. (2001). Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol. Rev. 53, 1-24.
    • (2001) Pharmacol. Rev , vol.53 , pp. 1-24
    • Ferguson, S.S.1
  • 18
    • 0035341213 scopus 로고    scopus 로고
    • Allosteric interactions between GB1 and GB2 subunits are required for optimal GABAB receptor function
    • Galvez, T., Duthey, B., Kniazeff, J., Blahos, J., Rovelli, G., Bettler, B., Prézeau, L. and Pin, J.-P. (2001). Allosteric interactions between GB1 and GB2 subunits are required for optimal GABAB receptor function. EMBO J. 20, 2152-2159.
    • (2001) EMBO J , vol.20 , pp. 2152-2159
    • Galvez, T.1    Duthey, B.2    Kniazeff, J.3    Blahos, J.4    Rovelli, G.5    Bettler, B.6    Prézeau, L.7    Pin, J.-P.8
  • 20
    • 34548273636 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid type B receptors are constitutively internalized via the clathrin-dependent pathway and targeted to lysosomes for degradation
    • Grampp, T., Sauter, K., Markovic, B. and Benke, D. (2007). Gamma-aminobutyric acid type B receptors are constitutively internalized via the clathrin-dependent pathway and targeted to lysosomes for degradation. J. Biol. Chem. 282, 24157-24165.
    • (2007) J. Biol. Chem , vol.282 , pp. 24157-24165
    • Grampp, T.1    Sauter, K.2    Markovic, B.3    Benke, D.4
  • 21
    • 56249127867 scopus 로고    scopus 로고
    • Constitutive, agonist-accelerated, recycling and lysosomal degradation of GABAB receptors in cortical neurons
    • Grampp, T., Notz, V., Broll, I., Fischer, N. and Benke, D. (2008). Constitutive, agonist-accelerated, recycling and lysosomal degradation of GABAB receptors in cortical neurons. Mol. Cell. Neurosci. 39, 628-637.
    • (2008) Mol. Cell. Neurosci , vol.39 , pp. 628-637
    • Grampp, T.1    Notz, V.2    Broll, I.3    Fischer, N.4    Benke, D.5
  • 24
    • 0033618396 scopus 로고    scopus 로고
    • Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein
    • Jordan, J. D., Carey, K. D., Stork, P. J. and Iyengar, R. (1999). Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein. J. Biol. Chem. 274, 21507-21510.
    • (1999) J. Biol. Chem , vol.274 , pp. 21507-21510
    • Jordan, J.D.1    Carey, K.D.2    Stork, P.J.3    Iyengar, R.4
  • 26
    • 0036759170 scopus 로고    scopus 로고
    • No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits
    • Kniazeff, J., Galvez, T., Labesse, G. and Pin, J. P. (2002). No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits. J. Neurosci. 22, 7352-7361.
    • (2002) J. Neurosci , vol.22 , pp. 7352-7361
    • Kniazeff, J.1    Galvez, T.2    Labesse, G.3    Pin, J.P.4
  • 28
    • 77956542058 scopus 로고    scopus 로고
    • Glycosylation and sialylation of macrophage-derived human apolipoprotein E analyzed by SDS-PAGE and mass spectrometry: evidence for a novel site of glycosylation on Ser290
    • Lee, Y., Kockx, M., Raftery, M. J., Jessup, W., Griffith, R. and Kritharides, L. (2010). Glycosylation and sialylation of macrophage-derived human apolipoprotein E analyzed by SDS-PAGE and mass spectrometry: evidence for a novel site of glycosylation on Ser290. Mol. Cell Proteomics 9, 1968-1981.
    • (2010) Mol. Cell Proteomics , vol.9 , pp. 1968-1981
    • Lee, Y.1    Kockx, M.2    Raftery, M.J.3    Jessup, W.4    Griffith, R.5    Kritharides, L.6
  • 29
    • 84860189221 scopus 로고    scopus 로고
    • An activity-based probe reveals dynamic protein-protein interactions mediating IGF-1R transactivation by the GABAB receptor
    • Lin, X., Li, X., Jiang, M., Chen, L., Xu, C., Zhang, W., Zhao, H., Sun, B., Xu, X., Nan, F. et al. (2012). An activity-based probe reveals dynamic protein-protein interactions mediating IGF-1R transactivation by the GABAB receptor. Biochem. J. 443, 627-634.
    • (2012) Biochem. J , vol.443 , pp. 627-634
    • Lin, X.1    Li, X.2    Jiang, M.3    Chen, L.4    Xu, C.5    Zhang, W.6    Zhao, H.7    Sun, B.8    Xu, X.9    Nan, F.10
  • 31
    • 0036473397 scopus 로고    scopus 로고
    • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
    • Luttrell, L. M. and Lefkowitz, R. J. (2002). The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J. Cell Sci. 115, 455-465.
    • (2002) J. Cell Sci , vol.115 , pp. 455-465
    • Luttrell, L.M.1    Lefkowitz, R.J.2
  • 32
    • 41749091359 scopus 로고    scopus 로고
    • Influence of positive allosteric modulators on GABAB receptor coupling in rat brain: a scintillation proximity assay characterisation of G protein subtypes
    • Mannoury la Cour, C., Herbelles, C., Pasteau, V., de Nanteuil, G. and Millan, M. J. (2008). Influence of positive allosteric modulators on GABAB receptor coupling in rat brain: a scintillation proximity assay characterisation of G protein subtypes. J. Neurochem. 105, 308-323.
    • (2008) J. Neurochem , vol.105 , pp. 308-323
    • Mannoury la Cour, C.1    Herbelles, C.2    Pasteau, V.3    de Nanteuil, G.4    Millan, M.J.5
  • 33
    • 0038487327 scopus 로고    scopus 로고
    • The ins and outs of G protein-coupled receptor trafficking
    • Marchese, A., Chen, C., Kim, Y.-M. and Benovic, J. L. (2003). The ins and outs of G protein-coupled receptor trafficking. Trends Biochem. Sci. 28, 369-376.
    • (2003) Trends Biochem. Sci , vol.28 , pp. 369-376
    • Marchese, A.1    Chen, C.2    Kim, Y.-M.3    Benovic, J.L.4
  • 35
    • 62549153648 scopus 로고    scopus 로고
    • Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology
    • McAvoy, T., Zhou, M.-m., Greengard, P. and Nairn, A. C. (2009). Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology. Proc. Natl. Acad. Sci. USA 106, 3531-3536.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3531-3536
    • McAvoy, T.1    Zhou, M.-M.2    Greengard, P.3    Nairn, A.C.4
  • 37
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • Moore, C. A. C., Milano, S. K. and Benovic, J. L. (2007). Regulation of receptor trafficking by GRKs and arrestins. Annu. Rev. Physiol. 69, 451-482.
    • (2007) Annu. Rev. Physiol , vol.69 , pp. 451-482
    • Moore, C.A.C.1    Milano, S.K.2    Benovic, J.L.3
  • 39
    • 0029107760 scopus 로고
    • The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue
    • Nassar, N., Horn, G., Herrmann, C., Scherer, A., McCormick, F. and Wittinghofer, A. (1995). The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. Nature 375, 554-560.
    • (1995) Nature , vol.375 , pp. 554-560
    • Nassar, N.1    Horn, G.2    Herrmann, C.3    Scherer, A.4    McCormick, F.5    Wittinghofer, A.6
  • 41
    • 0033434080 scopus 로고    scopus 로고
    • Probability-based protein identification by searching sequence databases using mass spectrometry data
    • Perkins, D. N., Pappin, D. J. C., Creasy, D. M. and Cottrell, J. S. (1999). Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 20, 3551-3567.
    • (1999) Electrophoresis , vol.20 , pp. 3551-3567
    • Perkins, D.N.1    Pappin, D.J.C.2    Creasy, D.M.3    Cottrell, J.S.4
  • 42
    • 0042575596 scopus 로고    scopus 로고
    • Phosphorylation-independent desensitization of GABAB receptor by GRK4
    • Perroy, J., Adam, L., Qanbar, R., Chénier, S. and Bouvier, M. (2003). Phosphorylation-independent desensitization of GABAB receptor by GRK4. EMBO J. 22, 3816-3824.
    • (2003) EMBO J , vol.22 , pp. 3816-3824
    • Perroy, J.1    Adam, L.2    Qanbar, R.3    Chénier, S.4    Bouvier, M.5
  • 43
    • 33947375174 scopus 로고    scopus 로고
    • Physiological roles of G protein-coupled receptor kinases and arrestins
    • Premont, R. T. and Gainetdinov, R. R. (2007). Physiological roles of G protein-coupled receptor kinases and arrestins. Annu. Rev. Physiol. 69, 511-534.
    • (2007) Annu. Rev. Physiol , vol.69 , pp. 511-534
    • Premont, R.T.1    Gainetdinov, R.R.2
  • 44
    • 66449105246 scopus 로고    scopus 로고
    • Specificity in Ras and Rap signaling
    • Raaijmakers, J. H. and Bos, J. L. (2009). Specificity in Ras and Rap signaling. J. Biol. Chem. 284, 10995-10999.
    • (2009) J. Biol. Chem , vol.284 , pp. 10995-10999
    • Raaijmakers, J.H.1    Bos, J.L.2
  • 46
    • 0035994379 scopus 로고    scopus 로고
    • Regulation of G-proteincoupled receptor activity by rab GTPases
    • Rosenfeld, J. L., Knoll, B. J. and Moore, R. H. (2002). Regulation of G-proteincoupled receptor activity by rab GTPases. Receptors Channels 8, 87-97.
    • (2002) Receptors Channels , vol.8 , pp. 87-97
    • Rosenfeld, J.L.1    Knoll, B.J.2    Moore, R.H.3
  • 49
    • 80052038573 scopus 로고    scopus 로고
    • beta-Arrestin-mediated receptor trafficking and signal transduction
    • Shenoy, S. K. and Lefkowitz, R. J. (2011). beta-Arrestin-mediated receptor trafficking and signal transduction. Trends Pharmacol. Sci. 32, 521-533.
    • (2011) Trends Pharmacol. Sci , vol.32 , pp. 521-533
    • Shenoy, S.K.1    Lefkowitz, R.J.2
  • 50
    • 77954913441 scopus 로고    scopus 로고
    • Sensory neuron-specific MAS-related gene-X1 receptors resist agonist-promoted endocytosis
    • Solinski, H. J., Boekhoff, I., Bouvier, M., Gudermann, T. and Breit, A. (2010). Sensory neuron-specific MAS-related gene-X1 receptors resist agonist-promoted endocytosis. Mol. Pharmacol. 78, 249-259.
    • (2010) Mol. Pharmacol , vol.78 , pp. 249-259
    • Solinski, H.J.1    Boekhoff, I.2    Bouvier, M.3    Gudermann, T.4    Breit, A.5
  • 53
    • 0034084767 scopus 로고    scopus 로고
    • Downregulation of G protein-coupled receptors
    • Tsao, P. and von Zastrow, M. (2000). Downregulation of G protein-coupled receptors. Curr. Opin. Neurobiol. 10, 365-369.
    • (2000) Curr. Opin. Neurobiol , vol.10 , pp. 365-369
    • Tsao, P.1    von Zastrow, M.2
  • 54
    • 0033603578 scopus 로고    scopus 로고
    • Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion
    • Tsukamoto, N., Hattori, M., Yang, H., Bos, J. L. and Minato, N. (1999). Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion. J. Biol. Chem. 274, 18463-18469.
    • (1999) J. Biol. Chem , vol.274 , pp. 18463-18469
    • Tsukamoto, N.1    Hattori, M.2    Yang, H.3    Bos, J.L.4    Minato, N.5
  • 55
    • 34447621270 scopus 로고    scopus 로고
    • Dominant role of GABAB2 and Gbetagamma for GABAB receptormediated-ERK1/2/CREB pathway in cerebellar neurons
    • Tu, H., Rondard, P., Xu, C., Bertaso, F., Cao, F., Zhang, X., Pin, J.-P. and Liu, J. (2007). Dominant role of GABAB2 and Gbetagamma for GABAB receptormediated-ERK1/2/CREB pathway in cerebellar neurons. Cell Signal. 19, 1996-2002.
    • (2007) Cell Signal , vol.19 , pp. 1996-2002
    • Tu, H.1    Rondard, P.2    Xu, C.3    Bertaso, F.4    Cao, F.5    Zhang, X.6    Pin, J.-P.7    Liu, J.8
  • 56
    • 74949134498 scopus 로고    scopus 로고
    • GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation
    • Tu, H., Xu, C., Zhang, W., Liu, Q., Rondard, P., Pin, J.-P. and Liu, J. (2010). GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation. J. Neurosci. 30, 749-759.
    • (2010) J. Neurosci , vol.30 , pp. 749-759
    • Tu, H.1    Xu, C.2    Zhang, W.3    Liu, Q.4    Rondard, P.5    Pin, J.-P.6    Liu, J.7
  • 59
    • 58049206253 scopus 로고    scopus 로고
    • Tracking cell surface GABAB receptors using an alpha-bungarotoxin tag
    • Wilkins, M. E., Li, X. and Smart, T. G. (2008). Tracking cell surface GABAB receptors using an alpha-bungarotoxin tag. J. Biol. Chem. 283, 34745-34752.
    • (2008) J. Biol. Chem , vol.283 , pp. 34745-34752
    • Wilkins, M.E.1    Li, X.2    Smart, T.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.