Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels

Molecular Neurobiology

Volumn 53, Issue 6, 2016, Pages 3540-3551

  Özdemir, Ümit Sinan ^a   Nazıroğlu, Mustafa ^b   Şenol, Nilgün ^a   Ghazizadeh, Vahid ^b  

^a SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b SULEYMAN DEMIREL UNIVERSITY   (Turkey)

Author keywords

Apoptosis; Hypericum perforatum; Oxidative stress; Spinal cord injury; TRPM2; TRPV1

Indexed keywords

CALCIUM ION; CAPSAICIN; CAPSAZEPINE; CASPASE 3; CASPASE 9; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYPERICUM PERFORATUM EXTRACT; REACTIVE OXYGEN METABOLITE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; VANILLOID RECEPTOR 1; CALCIUM; CASPASE; HYDROGEN PEROXIDE; PLANT EXTRACT; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, RAT; TRPV1 RECEPTOR; VANILLOID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; HYPERICUM PERFORATUM; LIPID PEROXIDATION; MALE; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; OXIDATIVE STRESS; RAT; SPINAL CORD INJURY; SPINAL GANGLION; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHANNEL GATING; CHEMISTRY; DRUG EFFECTS; HYPERICUM; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; PATHOLOGY; WISTAR RAT;

ANIMALS; APOPTOSIS; CALCIUM; CAPSAICIN; CASPASES; CELL SURVIVAL; GANGLIA, SPINAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYPERICUM; ION CHANNEL GATING; LIPID PEROXIDATION; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPINAL CORD INJURIES; TRPM CATION CHANNELS; TRPV CATION CHANNELS;

EID: 84932115742     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9292-1     Document Type: Article

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