Hypericum perforatum modulates apoptosis and calcium mobilization through voltage-gated and TRPM2 calcium channels in neutrophil of patients with Behcet's disease

Journal of Membrane Biology

Volumn 247, Issue 3, 2014, Pages 253-262

  Naziroǧlu, Mustafa ^a,b,c   Şahin, Mehmet ^b   Çiǧ, Bilal ^b   Aykur, Mehmet ^b   Erturan, Ijlal ^b   Ugan, Yunus ^b  

^a SULEYMAN DEMIREL UNIVERSITY   (Turkey)

^b SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^c WEILL CORNELL MEDICAL COLLEGE   (Qatar)

Author keywords

Antioxidant; Behcet's disease; Calcium ion; Hypericum perforatum; Inflammation; Oxidative stress

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; C REACTIVE PROTEIN; CALCIUM ION; CASPASE 3; CASPASE 9; DILTIAZEM; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; VERAPAMIL; VOLTAGE GATED CALCIUM CHANNEL;

APOPTOSIS; ARTICLE; BEHCET DISEASE; BLOOD SAMPLING; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME ACTIVITY; ERYTHROCYTE SEDIMENTATION RATE; HUMAN; HUMAN CELL; HYPERICUM PERFORATUM; LEUKOCYTE ACTIVATION; LIPID PEROXIDATION; NEUTROPHIL; OXIDATIVE STRESS; PROTEIN CONTENT;

HYPERICUM PERFORATUM;

ANTIOXIDANTS; APOPTOSIS; BEHCET SYNDROME; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CASE-CONTROL STUDIES; CASPASES; CELL SURVIVAL; ENZYME ACTIVATION; HUMANS; HYPERICUM; LIPID PEROXIDATION; NEUTROPHILS; PLANT EXTRACTS; TRPM CATION CHANNELS;

EID: 84900075511     PISSN: 00222631     EISSN: 14321424     Source Type: Journal    
DOI: 10.1007/s00232-014-9630-7     Document Type: Article

References (45)

1. 2+ influx shutdown during neutrophil apoptosis: importance and possible mechanism. Immunology 1:8-12
2. Behcet H (1937) Uber rezidivierende Aphthose, durch ein Virus verursachte Geschwure am Mund, am Auge und an den Genitalien. Dermatol Wochenschr 105:1152-1157
3. Bréchard S, Tschirhart EJ (2008) Regulation of superoxide production in neutrophils: role of calcium influx. J Leukoc Biol 84:1223-1237
4. Chatterjee S, Filippov V, Lishko P, Maximyuk O, Nöldner M, Krishtal O (1999) Hyperforin attenuates various ionic conductance mechanisms in the isolated hippocampal neurons of rat. Life Sci 65:405-2395
5. Direskeneli H (2001) Behçet's disease: infectious aetiolog, new autoantigens, and HLA-B51. Ann Rheum Dis 60:996-1002
6. Erkiliç K, Evereklioglu C, Cekmen M, Ozkiris A, Duygulu F, Dogan H (2003) Adenosine deaminase enzyme activity is increased and negatively correlates with catalase, superoxide dismutase and glutathione peroxidase in patients with Behçet's disease: original contributions/clinical and laboratory investigations. Mediators Inflamm 12:107-116 (Pubitemid 36783250)
7. Espino J, Mediero M, Bejarano I, Lozano GM, Ortiz A, García JF, Pariente JA, Rodríguez AB (2009) Reduced levels of intracellular calcium releasing in spermatozoa from asthenozoospermic patients. Reprod Biol Endoc 7:11
8. Espino J, Bejarano I, Redondo PC, Rosado JA, Barriga C, Reiter RJ, Pariente JA, Rodríguez AB (2010) Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: evidence for the involvement of mitochondria and Bax activation. J Membr Biol 233:105-118
9. Espino J, Bejarano I, Paredes SD, Barriga C, Rodríguez AB, Pariente JA (2011) Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions. J Pineal Res 51:195-206
10. Evereklioglu C (2005) Current concepts in the etiology and treatment of Behcet disease. Surv Ophthalmol 50:297-350
11. 2+ mobilization and functional leukocyte responses by hyperforin. Biochem Pharmacol 67(8):1531-1539
12. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
13. 2+ signalling. Eur J Biochem 249:55-547
14. Heilmann J, Winkelmann K, Sticher O (2003) Studies on the antioxidative activity of phloroglucinol derivatives isolated from hypericum species. Planta Med 69:202-226
15. Heiner I, Eisfeld J, Luckhoff A (2003) Role and regulation of TRP channels in neutrophil granulocytes. Cell Calcium 33:533-540 (Pubitemid 36748675)
16. Jang MH, Lee TH, Shin MC, Bahn GH, Kim JW, Shin DH, Kim EH, Kim CJ (2002) Protective effect of Hypericum perforatum Linn (St. John's wort) against hydrogen peroxide-induced apoptosis on human neuroblastoma cells. Neurosci Lett 329:177-180
17. Karaman A, Kadi M, Kara F (2009) Sister chromatid exchange and micronucleus studies in patients with Behçet's disease. J Cutan Pathol 36:831-837
18. Kökçam I, Naziroglu M (2002) Effects of vitamin E supplementation on blood antioxidants levels in patients with Behçet's diseas. Clin Biochem 35:633-639 (Pubitemid 36009331)
19. 2+ release and antioxidant system. J Membr Biol 244:113-120
20. Krishtal O, Lozovaya N, Fisunov A, Tsintsadze T, Pankratov Y, Kopanitsa M, Chatterjee SS (2001) Modulation of ion channels in rat neurons by the constituents of Hypericum perforatum. Pharmacopsychiatry 34(Suppl 1):S74-S82
21. Lawrence RA, Burk RF (1976) Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 71:952-958
22. Lin Y, Zhang JC, Fu J, Chen F, Wang J, Wu ZL, Yuan SY (2013) Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation. J Cereb Blood Flow Metab 33(2):62-253
23. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin-phenol reagent. J Biol Chem 193:265-275
24. Meinke MC, Schanzer S, Haag SF, Casetti F, Müller ML, Wölfle U, Kleemann A, Lademann J, Schempp CM (2012) In vivo photoprotective and anti-inflammatory effect of hyperforin is associated with high antioxidant activity in vitro and ex vivo. Eur J Pharm Biopharm 81(2):346-350
25. Naziroǧlu M (2007) New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose. Neurochem Res 32:1990-2001
26. Naziroǧlu M (2009) Role of selenium on calcium signaling and oxidative stress- induced molecular pathways in epilepsy. Neurochem Res 34:219-2181
27. Naziroǧlu M (2011) TRPM2 cation channels, oxidative stress and neurological diseases: where are we now? Neurochem Res 36:355-366
28. Naziroǧlu M, Karaoǧlu A, Aksoy AO (2004) Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats. Toxicology 195(2-3):30-221
29. 2+ influx and oxidative stress through TRPM2 channel in rat dorsal root ganglion neurons. J Membr Biol 242(3):18-109
30. 2+ signaling on molecular pathways of neuropathic pain in diabetes: focus on TRP channels. Neurochem Res 37:75-2065
31. 2+ influx in dorsal root ganglion neurons of mice: role of TRPV1 channels. Neuroscience 242:151-160
32. 2+ mobilization through TRPM2 channels in rat dorsal root ganglion neuron by Hypericum perforatum. Neuroscience. doi:10.1016/j.neuroscience.2014.01.006
33. Naziroǧlu M, Kutluhan S, Övey İS, Aykur M, Yurekli VA (2014b) Modulation of oxidative stress, apoptosis, and calcium entry in leukocytes of patients with multiple sclerosis by Hypericum perforatum. NutrNeurosci. doi:10.1179/1476830513Y.0000000083
34. Öztaş P, Lortlar N, Polat M, Alli N, Ömeroǧlu S, Basman A (2007) Caspase-9 expression is increased in endothelial cells of active Behçet's disease patients. Intern J Dermatol 46:172-176 (Pubitemid 46671694)
35. Placer ZA, Cushman L, Johnson BC (1966) Estimation of products of lipid peroxidation (malonyl dialdehyde) in biological fluids. Anal Biochem 16:359-364
36. Şahin M, Uguz AC, Demirkan H, Naziroglu M (2011) Colchicine modulates oxidative stress in serum and leucocytes from remission patients with Family Mediterranean Fever through regulation of Ca(2)+ release and the antioxidant system. J Membr Biol 240:55-62
37. Sandikci R, Türkmen S, Güvenen G, Ayabakan H, Gülcan P, Koldas M, Ozbek Kir Z, Yenice N (2003) Lipid peroxidation and antioxidant defence system in patients with active or inactive Behcet's disease. Acta Derm Venereol 83:6-342
38. Sedlak J, Lindsay RHC (1968) Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellmann' s reagent. Anal Biochem 25:192-205
39. Shima E, Katsube M, Kato T, Kitagawa M, Hato F, Hino M, Takahashi T, Fujita H, Kitagawa S (2008) Calcium channel blockers suppress cytokine-induced activation of human neutrophils. Am J Hypertens 21:78-84
40. Tamer A, Gheita TA, Bassyouni IH, Bassyouni RH (2012) Plasma concentrations of growth arrest specific protein 6 and the soluble form of its tyrosine kinase receptor Axl in patients with systemic lupus erythematosus and Behçets disease. J Clin Immunol 32:1279-1286
41. Taysi S, Kocer I, Memisogullari R, Kiziltunc A (2002) Serum oxidant/antioxidant status in patients with Behcet's disease. Ann Clin Lab Sci 2002(32):82-377
42. Todaro M, Zerilli M, Triolo G, Flora Iovino F, Patti M, Accardo-Palumbo A, di Gaudio F, TurcoPetrella MC, Petrella A, de Maria R, Stassi G (2005) NF-kB protects Behcet's disease T cells against CD95-induced apoptosis up-regulating antiapoptotic proteins. Arthritis Rheum 52:2179-2191 (Pubitemid 40994341)
43. Uǧuz AC, Naziroǧlu M, Espino J, Bejarano I, González D, Rodríguez AB, Pariente JA (2009) Selenium modulates oxidative stressinduced cell apoptosis in human myeloid HL-60 cells via regulation of caspase-3, -9 and calcium influx. J Membr Biol 232:15-23
44. Uǧuz AC, Cig B, Espino J, Bejarano I, Naziroglu M, Rodríguez AB, Pariente JA (2012) Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells. J Pineal Res 53:91-98
45. Uǧuz AC, Naziroǧlu M (2012) Effects of selenium on calcium signaling and apoptosis in rat dorsal root ganglion neurons induced by oxidative stress. Neurochem Res 37:1631-1638