-
1
-
-
0030954681
-
Defects in yolk sac hematopoiesis in Mll-null embryos
-
Hess JL, Yu BD, Li B, et al. Defects in yolk sac hematopoiesis in Mll-null embryos. Blood 1997;90:1799-1806.
-
(1997)
Blood
, vol.90
, pp. 1799-1806
-
-
Hess, J.L.1
Yu, B.D.2
Li, B.3
-
2
-
-
0035864734
-
Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4:11) abnormality
-
Rozovskaia T, Feinstein E, Mor O, et al. Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4:11) abnormality. Oncogene 2001;20:874-878.
-
(2001)
Oncogene
, vol.20
, pp. 874-878
-
-
Rozovskaia, T.1
Feinstein, E.2
Mor, O.3
-
3
-
-
78650333017
-
Mechanisms of leukemogenesis by MLL fusion proteins
-
Marschalek R. Mechanisms of leukemogenesis by MLL fusion proteins. Br J Haematol 2011;152:141-154.
-
(2011)
Br J Haematol
, vol.152
, pp. 141-154
-
-
Marschalek, R.1
-
4
-
-
68749120703
-
New insights to the MLL recombinome of acute leukemias
-
Meyer C, Kowarz E, Hofmann J, et al. New insights to the MLL recombinome of acute leukemias. Leukemia 2009;23:1490-1499.
-
(2009)
Leukemia
, vol.23
, pp. 1490-1499
-
-
Meyer, C.1
Kowarz, E.2
Hofmann, J.3
-
5
-
-
84887320453
-
Te MLL recombinome of acute leukemias in 2013
-
Meyer C, Hofmann J, Burmeister T, et al. Te MLL recombinome of acute leukemias in 2013. Leukemia 2013;27:2165-2176.
-
(2013)
Leukemia
, vol.27
, pp. 2165-2176
-
-
Meyer, C.1
Hofmann, J.2
Burmeister, T.3
-
6
-
-
84875811765
-
Te distribution of MLL breakpoints correlates with outcome in infant acute leukaemia
-
Emerenciano M, Meyer C, Mansur MB, et al. Te distribution of MLL breakpoints correlates with outcome in infant acute leukaemia. Br J Haematol 2013;161:224-236.
-
(2013)
Br J Haematol
, vol.161
, pp. 224-236
-
-
Emerenciano, M.1
Meyer, C.2
Mansur, M.B.3
-
8
-
-
0027172909
-
Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specifc biologic variables and poor outcome
-
Chen CS, Sorensen PH, Domer PH, et al. Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specifc biologic variables and poor outcome. Blood 1993;81:2386-2393.
-
(1993)
Blood
, vol.81
, pp. 2386-2393
-
-
Chen, C.S.1
Sorensen, P.H.2
Domer, P.H.3
-
9
-
-
0027276927
-
In utero rearrangements in the trithorax-related oncogene in infant leukaemias
-
Ford AM, Ridge SA, Cabrera ME, et al. In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 1993; 363:358-360.
-
(1993)
Nature
, vol.363
, pp. 358-360
-
-
Ford, A.M.1
Ridge, S.A.2
Cabrera, M.E.3
-
10
-
-
0031471132
-
Backtracking leukemia to birth: Identifcation of clonotypic gene fusion sequences in neonatal blood spots
-
Gale KB, Ford AM, Repp R, et al. Backtracking leukemia to birth: identifcation of clonotypic gene fusion sequences in neonatal blood spots. Proc Natl Acad Sci USA 1997;94:13950-13954.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13950-13954
-
-
Gale, K.B.1
Ford, A.M.2
Repp, R.3
-
11
-
-
0141482011
-
Leukemia in twins: Lessons in natural history
-
Greaves M F, Maia AT, Wiemels JL, et al. Leukemia in twins: lessons in natural history. Blood 2003;102:2321-2333.
-
(2003)
Blood
, vol.102
, pp. 2321-2333
-
-
Greaves, M.F.1
Maia, A.T.2
Wiemels, J.L.3
-
12
-
-
33846635607
-
Birth characteristics, maternal reproductive history, and the risk of infant leukemia: A report from the Children's Oncology Group
-
Spector LG, Davies SM, Robison LL, et al. Birth characteristics, maternal reproductive history, and the risk of infant leukemia: a report from the Children's Oncology Group. Cancer Epidemiol Biomarkers Prev 2007;16:128-134.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 128-134
-
-
Spector, L.G.1
Davies, S.M.2
Robison, L.L.3
-
13
-
-
68549135307
-
Rearrangements of the MLL gene are infuenced by DNA secondary structure, potentially mediated by topoisomerase II binding
-
Le H, Singh S, Shih SJ, et al. Rearrangements of the MLL gene are infuenced by DNA secondary structure, potentially mediated by topoisomerase II binding. Genes Chromosomes Cancer 2009;48:806-815.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 806-815
-
-
Le Singh H, S.1
Shih, S.J.2
-
14
-
-
0031011855
-
DNA cleavage within the MLL breakpoint cluster region is a specifc event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis
-
Stanulla M, Wang J, Chervinsky DS, et al. DNA cleavage within the MLL breakpoint cluster region is a specifc event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis. Mol Cell Biol 1997;17:4070-4079.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4070-4079
-
-
Stanulla, M.1
Wang, J.2
Chervinsky, D.S.3
-
15
-
-
33751072676
-
Nucleotide-resolution mapping of topoisomerase-mediated and apoptotic DNA strand scissions at or near an MLL translocation hotspot
-
Mirault ME, Boucher P, Tremblay A. Nucleotide-resolution mapping of topoisomerase-mediated and apoptotic DNA strand scissions at or near an MLL translocation hotspot. Am J Hum Genet 2006;79:779-791.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 779-791
-
-
Mirault, M.E.1
Boucher, P.2
Tremblay, A.3
-
16
-
-
0034970067
-
An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners
-
Huret JL, Dessen P, Bernheim A. An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners. Leukemia 2001;15:987-989.
-
(2001)
Leukemia
, vol.15
, pp. 987-989
-
-
Huret, J.L.1
Dessen, P.2
Bernheim, A.3
-
17
-
-
33646161959
-
Te MLL recombinome of acute leukemias
-
Meyer C, Schneider B, Jakob S, et al. Te MLL recombinome of acute leukemias. Leukemia 2006;20:777-784.
-
(2006)
Leukemia
, vol.20
, pp. 777-784
-
-
Meyer, C.1
Schneider, B.2
Jakob, S.3
-
18
-
-
67649366423
-
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells
-
Schnyder S, Du NT, Le HB, et al. Estrogen treatment induces MLL aberrations in human lymphoblastoid cells. Leuk Res 2009; 33:1400-1404.
-
(2009)
Leuk Res
, vol.33
, pp. 1400-1404
-
-
Schnyder, S.1
Du, N.T.2
Le, H.B.3
-
19
-
-
33847400116
-
Transcription linked to recombination: A gene-internal promoter coincides with the recombination hot spot II of the human MLL gene
-
Scharf S, Zech J, Bursen A, et al. Transcription linked to recombination: a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene. Oncogene 2007;26:1361-1371.
-
(2007)
Oncogene
, vol.26
, pp. 1361-1371
-
-
Scharf, S.1
Zech, J.2
Bursen, A.3
-
20
-
-
71249101060
-
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specifc translocations in cancer
-
Lin C, Yang L, Tanasa B, et al. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specifc translocations in cancer. Cell 2009;139:1069-1083.
-
(2009)
Cell
, vol.139
, pp. 1069-1083
-
-
Lin, C.1
Yang, L.2
Tanasa, B.3
-
21
-
-
34548565667
-
Quantitative analysis of chromosome conformation capture assays (3C-qPCR)
-
Hagege H, Klous P, Braem C, et al. Quantitative analysis of chromosome conformation capture assays (3C-qPCR). Nat Protoc 2007;2:1722-1733.
-
(2007)
Nat Protoc
, vol.2
, pp. 1722-1733
-
-
Hagege, H.1
Klous, P.2
Braem, C.3
-
22
-
-
33644779843
-
Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited
-
Gue M, Sun JS, Boudier T. Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited. BMC Cancer 2006;6:20.
-
(2006)
BMC Cancer
, vol.6
, pp. 20
-
-
Gue, M.1
Sun, J.S.2
Boudier, T.3
-
23
-
-
84861850399
-
Model for MLL translocations in therapy-related leukemia involving topoisomerase IIbeta-mediated DNA strand breaks and gene proximity
-
Cowell IG, Sondka Z, Smith K, et al. Model for MLL translocations in therapy-related leukemia involving topoisomerase IIbeta-mediated DNA strand breaks and gene proximity. Proc Natl Acad Sci USA 2012;109:8989-8994.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 8989-8994
-
-
Cowell, I.G.1
Sondka, Z.2
Smith, K.3
-
24
-
-
0030608376
-
Alternative RNA splicing of the MLL gene in normal and malignant cells
-
Nam DK, Honoki K, Yu M, et al. Alternative RNA splicing of the MLL gene in normal and malignant cells. Gene 1996;178: 169-175.
-
(1996)
Gene
, vol.178
, pp. 169-175
-
-
Nam, D.K.1
Honoki, K.2
Yu, M.3
-
25
-
-
0028952407
-
Molecular analysis of the Mono Mac 6 cell line: Detection of an MLL-AF9 fusion transcript
-
Super HJ, Martinez-Climent J, Rowley JD. Molecular analysis of the Mono Mac 6 cell line: detection of an MLL-AF9 fusion transcript. Blood 1995;85:855-856.
-
(1995)
Blood
, vol.85
, pp. 855-856
-
-
Super, H.J.1
Martinez-Climent, J.2
Rowley, J.D.3
-
26
-
-
57149146036
-
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
-
Robbiani DF, Bothmer A, Callen E, et al. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 2008;135:1028-1038.
-
(2008)
Cell
, vol.135
, pp. 1028-1038
-
-
Robbiani, D.F.1
Bothmer, A.2
Callen, E.3
-
27
-
-
84867283407
-
IgH partner breakpoint sequences provide evidence that AID initiates t(11;14) and t(8;14) chromosomal breaks in mantle cell and Burkitt lymphomas
-
Greisman HA, Lu Z, Tsai AG, et al. IgH partner breakpoint sequences provide evidence that AID initiates t(11;14) and t(8;14) chromosomal breaks in mantle cell and Burkitt lymphomas. Blood 2012;120:2864-2867.
-
(2012)
Blood
, vol.120
, pp. 2864-2867
-
-
Greisman, H.A.1
Lu, Z.2
Tsai, A.G.3
-
28
-
-
33646148512
-
Ig class switching: Targeting the recombinational mechanism
-
Selsing E. Ig class switching: targeting the recombinational mechanism. Curr Opin Immunol 2006;18:249-254.
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 249-254
-
-
Selsing, E.1
-
29
-
-
70449641054
-
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations
-
Robbiani DF, Bunting S, Feldhahn N, et al. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol Cell 2009;36:631-641.
-
(2009)
Mol Cell
, vol.36
, pp. 631-641
-
-
Robbiani, D.F.1
Bunting, S.2
Feldhahn, N.3
-
30
-
-
38049012778
-
Regulation of aicda expression and AID activity: Relevance to somatic hypermutation and class switch DNA recombination
-
Xu Z, Pone EJ, Al-Qahtani A, et al. Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Crit Rev Immunol 2007;27:367-397.
-
(2007)
Crit Rev Immunol
, vol.27
, pp. 367-397
-
-
Xu, Z.1
Pone, E.J.2
Al-Qahtani, A.3
-
31
-
-
77955964086
-
AID and somatic hypermutation
-
Maul RW, Gearhart PJ. AID and somatic hypermutation. Adv Immunol 2010;105:159-191.
-
(2010)
Adv Immunol
, vol.105
, pp. 159-191
-
-
Maul, R.W.1
Gearhart, P.J.2
-
32
-
-
84866318176
-
Multiple clonal MLL fusions in a patient receiving CHOP-based chemotherapy
-
Shih SJ, Fass J, Bufalo V, et al. Multiple clonal MLL fusions in a patient receiving CHOP-based chemotherapy. Br J Haematol 2012;159:50-57.
-
(2012)
Br J Haematol
, vol.159
, pp. 50-57
-
-
Shih, S.J.1
Fass, J.2
Bufalo, V.3
-
33
-
-
84865191566
-
AIDing the immune system-DIAbolic in cancer
-
Schmitz KM, Petersen-Mahrt SK. AIDing the immune system-DIAbolic in cancer. Semin Immunol 2012;24:241-245.
-
(2012)
Semin Immunol
, vol.24
, pp. 241-245
-
-
Schmitz, K.M.1
Petersen-Mahrt, S.K.2
-
34
-
-
77957239251
-
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5
-
Pavri R, Gazumyan A, Jankovic M, et al. Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell 2010;143:122-133.
-
(2010)
Cell
, vol.143
, pp. 122-133
-
-
Pavri, R.1
Gazumyan, A.2
Jankovic, M.3
-
35
-
-
0037926476
-
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
-
Pham P, Bransteitter R, Petruska J, et al. Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation. Nature 2003;424:103-107.
-
(2003)
Nature
, vol.424
, pp. 103-107
-
-
Pham, P.1
Bransteitter, R.2
Petruska, J.3
-
36
-
-
66049129496
-
Te activation-induced cytidine deaminase (AID) efciently targets DNA in nucleosomes but only during transcription
-
Shen HM, Poirier MG, Allen MJ, et al. Te activation-induced cytidine deaminase (AID) efciently targets DNA in nucleosomes but only during transcription. J Exp Med 2009;206:1057-1071.
-
(2009)
J Exp Med
, vol.206
, pp. 1057-1071
-
-
Shen, H.M.1
Poirier, M.G.2
Allen, M.J.3
-
37
-
-
77950934774
-
Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment
-
Jung R, Jacobs U, Krumbholz M, et al. Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment. Leukemia 2010;24:903-907.
-
(2010)
Leukemia
, vol.24
, pp. 903-907
-
-
Jung, R.1
Jacobs, U.2
Krumbholz, M.3
-
39
-
-
20144389914
-
Maternal diet and infant leukemia: The DNA topoisomerase II inhibitor hypothesis: A report from the children's oncology group
-
Spector LG, Xie Y, Robison LL, et al. Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group. Cancer Epidemiol Biomarkers Prev 2005;14:651-655.
-
(2005)
Cancer Epidemiol Biomarkers Prev
, vol.14
, pp. 651-655
-
-
Spector, L.G.1
Xie, Y.2
Robison, L.L.3
-
40
-
-
66649123137
-
MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals
-
Brassesco MS, Montaldi AP, Gras DE, et al. MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals. Genet Mol Biol 2009;32:234-241.
-
(2009)
Genet Mol Biol
, vol.32
, pp. 234-241
-
-
Brassesco, M.S.1
Montaldi, A.P.2
Gras, D.E.3
-
41
-
-
0032170594
-
Partial tandem duplications of the MLL gene are detectable in peripheral blood and bone marrow of nearly all healthy donors
-
Schnittger S, Wormann B, Hiddemann W, et al. Partial tandem duplications of the MLL gene are detectable in peripheral blood and bone marrow of nearly all healthy donors. Blood 1998;92:1728-1734.
-
(1998)
Blood
, vol.92
, pp. 1728-1734
-
-
Schnittger, S.1
Wormann, B.2
Hiddemann, W.3
-
42
-
-
33745830494
-
Lifelong persistence of AML associated MLL partial tandem duplications (MLL-PTD) in healthy adults
-
Basecke J, Podleschny M, Clemens R, et al. Lifelong persistence of AML associated MLL partial tandem duplications (MLL-PTD) in healthy adults. Leuk Res 2006;30:1091-1096.
-
(2006)
Leuk Res
, vol.30
, pp. 1091-1096
-
-
Basecke, J.1
Podleschny, M.2
Clemens, R.3
-
43
-
-
0036935075
-
Leukemia-and lymphoma-associated genetic aberrations in healthy individuals
-
Basecke J, Griesinger F, Trumper L, et al. Leukemia-and lymphoma-associated genetic aberrations in healthy individuals. Ann Hematol 2002;81:64-75.
-
(2002)
Ann Hematol
, vol.81
, pp. 64-75
-
-
Basecke, J.1
Griesinger, F.2
Trumper, L.3
-
44
-
-
0037062496
-
Chromosome translocations and covert leukemic clones are generated during normal fetal development
-
Mori H, Colman SM, Xiao Z, et al. Chromosome translocations and covert leukemic clones are generated during normal fetal development. Proc Natl Acad Sci USA 2002;99:8242-8247.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8242-8247
-
-
Mori, H.1
Colman, S.M.2
Xiao, Z.3
-
45
-
-
0035863493
-
Frequency of the Bcl-2/IgH rearrangement in normal individuals: Implications for the monitoring of disease in patients with follicular lymphoma
-
Summers KE, Gof LK, Wilson AG, et al. Frequency of the Bcl-2/IgH rearrangement in normal individuals: implications for the monitoring of disease in patients with follicular lymphoma. J Clin Oncol 2001;19:420-424.
-
(2001)
J Clin Oncol
, vol.19
, pp. 420-424
-
-
Summers, K.E.1
Gof, L.K.2
Wilson, A.G.3
|