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Volumn 178, Issue 1-2, 1996, Pages 169-175

Alternative RNA splicing of the MLL gene in normal and malignant cells

Author keywords

Alternative RNA splicing; Cloning; DNA sequencing; Hematopoietic cells; Homeobox genes; Leukemia; MLL protein motifs; Northern blot; RT PCR

Indexed keywords

MESSENGER RNA; ZINC FINGER PROTEIN;

EID: 0030608376     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(96)00364-2     Document Type: Article
Times cited : (29)

References (38)
  • 1
    • 0024121631 scopus 로고
    • Nonsense mutation in the human β-globin gene affect mRNA metabolism
    • Baserga, S. and Benz Jr., E.J. (1988) Nonsense mutation in the human β-globin gene affect mRNA metabolism. Proc. Natl. Acad. Sci. USA 85, 2956-2060.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2956-12060
    • Baserga, S.1    Benz E.J., Jr.2
  • 2
    • 0026720732 scopus 로고
    • Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt 1 gene transcript
    • Bickmore, W.A., Oghene, K., Little, M.H., Seawright, A., van Heyningen, V. and Hastie, N.D. (1992) Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt 1 gene transcript. Science 257, 235-237.
    • (1992) Science , vol.257 , pp. 235-237
    • Bickmore, W.A.1    Oghene, K.2    Little, M.H.3    Seawright, A.4    Van Heyningen, V.5    Hastie, N.D.6
  • 3
    • 0028205863 scopus 로고
    • Evolutionary conservation of the structure and expression of alternatively spliced Ultrabithorax isoforms from Drosophila
    • Bomze, H.M. and Lopez, A.J. (1995) Evolutionary conservation of the structure and expression of alternatively spliced Ultrabithorax isoforms from Drosophila. Genetics 136, 965-977.
    • (1995) Genetics , vol.136 , pp. 965-977
    • Bomze, H.M.1    Lopez, A.J.2
  • 4
    • 0027536183 scopus 로고
    • Trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each
    • Breen, T.R. and Harte, P.J. (1993) Trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 117, 119-134.
    • (1993) Development , vol.117 , pp. 119-134
    • Breen, T.R.1    Harte, P.J.2
  • 5
    • 0027714991 scopus 로고
    • Multiple closely-linked NFAT/ octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter
    • Chuvpilo, S., Schomberg, C., Gerwig, R., Heingfing, A., Reeves, R., Grummt, F and Serfling, E. (1993) Multiple closely-linked NFAT/ octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter. Nucleic Acids Res. 21, 5694-5704.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5694-5704
    • Chuvpilo, S.1    Schomberg, C.2    Gerwig, R.3    Heingfing, A.4    Reeves, R.5    Grummt, F.6    Serfling, E.7
  • 7
    • 0028587828 scopus 로고
    • Insect proteins homologous to mammalian high mobility group proteins I/Y (HMG I/Y); characterization and binding to linear and four-way junction DNA
    • Claus, P., Schulze, E. and Wisniewski, J.R. (1994) Insect proteins homologous to mammalian high mobility group proteins I/Y (HMG I/Y); characterization and binding to linear and four-way junction DNA. J. Biol. Chem. 269, 33042-33048.
    • (1994) J. Biol. Chem. , vol.269 , pp. 33042-33048
    • Claus, P.1    Schulze, E.2    Wisniewski, J.R.3
  • 9
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Devereux, J., Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12, 387-395.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Devereux, J.1    Haeberli, P.2    Smithies, O.3
  • 10
    • 0026936328 scopus 로고
    • A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukemias
    • Djabali, M., Selleri, L., Parry, P., Bower, M., Young, B.D. and Evans, G.A. (1992) A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukemias. Nat. Genet. 2, 113-118.
    • (1992) Nat. Genet. , vol.2 , pp. 113-118
    • Djabali, M.1    Selleri, L.2    Parry, P.3    Bower, M.4    Young, B.D.5    Evans, G.A.6
  • 12
    • 0027165839 scopus 로고
    • Organization, inducible-expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene
    • Friedmann, M., Holth, L.T., Zoghbi, H.Y. and Reeves, R. (1993) Organization, inducible-expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene. Nucleic Acids Res. 21, 4259-4267.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4259-4267
    • Friedmann, M.1    Holth, L.T.2    Zoghbi, H.Y.3    Reeves, R.4
  • 13
    • 0026496887 scopus 로고
    • The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
    • Gu, Y., Nakamura, T., Alder, H., Prasad, R., Canaani, O., Cimino, G., Croce, C.M. and Canaani, E. (1992) The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell 71, 701-708.
    • (1992) Cell , vol.71 , pp. 701-708
    • Gu, Y.1    Nakamura, T.2    Alder, H.3    Prasad, R.4    Canaani, O.5    Cimino, G.6    Croce, C.M.7    Canaani, E.8
  • 15
    • 0028319671 scopus 로고
    • The generation of protein isoform diversity by alternative RNA splicing
    • Helfman, D.M. (1994) The generation of protein isoform diversity by alternative RNA splicing. Soc. Gen. Physiol. Ser. 49, 105-115.
    • (1994) Soc. Gen. Physiol. Ser. , vol.49 , pp. 105-115
    • Helfman, D.M.1
  • 16
    • 0028139772 scopus 로고
    • Genetic and biochemical analysis of alternative RNA splicing
    • Hodges, D. and Bernstein, S.I. (1994) Genetic and biochemical analysis of alternative RNA splicing. Adv. Genet. 31, 207-281.
    • (1994) Adv. Genet. , vol.31 , pp. 207-281
    • Hodges, D.1    Bernstein, S.I.2
  • 17
    • 0026776153 scopus 로고
    • Multiple zinc finger forms resulting from developmentally regulated alternative splicing of a transcription factor gene
    • Hsu, T., Gogos, J.A., Kirsh, S.A. and Kafatos, F.C. (1992) Multiple zinc finger forms resulting from developmentally regulated alternative splicing of a transcription factor gene. Science 257, 1946-1950.
    • (1992) Science , vol.257 , pp. 1946-1950
    • Hsu, T.1    Gogos, J.A.2    Kirsh, S.A.3    Kafatos, F.C.4
  • 18
    • 0026485281 scopus 로고
    • Homeobox genes in normal hematopoiesis and leukemia
    • Lawrence, H.J. and Largman, C. (1992) Homeobox genes in normal hematopoiesis and leukemia. Blood 80, 2445-2453.
    • (1992) Blood , vol.80 , pp. 2445-2453
    • Lawrence, H.J.1    Largman, C.2
  • 19
    • 0023652355 scopus 로고
    • Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/ CGRP gene expression
    • Leff, S.E., Evans, R.M. and Rosenfield, M.G. (1987) Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/ CGRP gene expression. Cell 48, 517-524.
    • (1987) Cell , vol.48 , pp. 517-524
    • Leff, S.E.1    Evans, R.M.2    Rosenfield, M.G.3
  • 21
    • 0025247728 scopus 로고
    • The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains
    • Mazo, A.M., Huang, D.-H., Mozer, B.A. and Dawid, I.B. (1990) The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains. Proc. Natl. Acad. Sci. USA 87, 2112-2116.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2112-2116
    • Mazo, A.M.1    Huang, D.-H.2    Mozer, B.A.3    Dawid, I.B.4
  • 22
    • 0040215628 scopus 로고
    • Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
    • Miller, J., McLachlan, A.D. and Klug, A. (1985) Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J. 4, 1609-1614.
    • (1985) EMBO J. , vol.4 , pp. 1609-1614
    • Miller, J.1    McLachlan, A.D.2    Klug, A.3
  • 25
    • 0025196283 scopus 로고
    • The A · T-DNA-binding domain of mammalian high mobility group I chromosomal proteins: A novel peptide motif for recognizing DNA structure
    • Reeves, R. and Nissen, M.S. (1990) The A · T-DNA-binding domain of mammalian high mobility group I chromosomal proteins: a novel peptide motif for recognizing DNA structure. J. Biol. Chem. 265, 8573-8582.
    • (1990) J. Biol. Chem. , vol.265 , pp. 8573-8582
    • Reeves, R.1    Nissen, M.S.2
  • 27
    • 0027998890 scopus 로고
    • ALL-1 tandem duplication in acute myeloid leukemia with a normal karyotype involves homologous recombination between Alu elements
    • Schichman, S.A., Caligiuri, M.A., Strout, M.P., Carter, S.L., Gu, Y., Canaani, E., Bloomfield, C.D. and Croce, C.M. (1994) ALL-1 tandem duplication in acute myeloid leukemia with a normal karyotype involves homologous recombination between Alu elements. Cancer Res. 54, 4277-4280.
    • (1994) Cancer Res. , vol.54 , pp. 4277-4280
    • Schichman, S.A.1    Caligiuri, M.A.2    Strout, M.P.3    Carter, S.L.4    Gu, Y.5    Canaani, E.6    Bloomfield, C.D.7    Croce, C.M.8
  • 28
    • 0028980320 scopus 로고
    • Self-fusion of the ALL1 gene: A new genetic mechanism for acute leukemia
    • Schichman, S.A., Canaani, E. and Croce, C.M. (1995) Self-fusion of the ALL1 gene: a new genetic mechanism for acute leukemia. J. Am. Med. Assoc. 273, 571-576.
    • (1995) J. Am. Med. Assoc. , vol.273 , pp. 571-576
    • Schichman, S.A.1    Canaani, E.2    Croce, C.M.3
  • 29
    • 0017702412 scopus 로고
    • Characterization of EBV-genome negative 'Null' and 'T' cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma
    • Schneider, U., Schwenk, H.U. and Bornkamm, G. (1977) Characterization of EBV-genome negative 'Null' and 'T' cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int. J. Cancer 19, 621-626.
    • (1977) Int. J. Cancer , vol.19 , pp. 621-626
    • Schneider, U.1    Schwenk, H.U.2    Bornkamm, G.3
  • 30
    • 0028264508 scopus 로고
    • The bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the Antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts
    • Sedkov, Y., Tillib, S., Mizrokhi, L. and Mazo, A. (1994) The bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the Antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts. Development 120, 1907-1917.
    • (1994) Development , vol.120 , pp. 1907-1917
    • Sedkov, Y.1    Tillib, S.2    Mizrokhi, L.3    Mazo, A.4
  • 31
    • 0017155490 scopus 로고
    • Establishment and characterization of a human histiocytic lymphoma cell line (U-937)
    • Sundström, C. and Nilsson, K. (1976) Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int. J. Cancer 17, 565-577.
    • (1976) Int. J. Cancer , vol.17 , pp. 565-577
    • Sundström, C.1    Nilsson, K.2
  • 32
    • 0026489365 scopus 로고
    • The high mobility group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene
    • Thanos, D. and Maniatis, T. (1992) The high mobility group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene. Cell 71, 777-789.
    • (1992) Cell , vol.71 , pp. 777-789
    • Thanos, D.1    Maniatis, T.2
  • 33
    • 0001788530 scopus 로고
    • The use of synthetic oligonucleotides as specific hybridization probes in the diagnosis of genetic disorders
    • K.E. Davis (Ed.). IRL Press, Herndon, VA
    • Thein, S.L. and Wallace, R.B. (1986) The use of synthetic oligonucleotides as specific hybridization probes in the diagnosis of genetic disorders. In: K.E. Davis (Ed.) Human Genetic Diseases: A Practical Approach. IRL Press, Herndon, VA, 33-50.
    • (1986) Human Genetic Diseases: A Practical Approach , pp. 33-50
    • Thein, S.L.1    Wallace, R.B.2
  • 34
    • 0026454451 scopus 로고
    • Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
    • Tkachuk, D.C., Kohler, S. and Cleary, M.L. (1992) Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71, 691-700.
    • (1992) Cell , vol.71 , pp. 691-700
    • Tkachuk, D.C.1    Kohler, S.2    Cleary, M.L.3
  • 36
    • 0029977830 scopus 로고    scopus 로고
    • MLL tandem duplication and multiple splicing in acute myelogenous leukemia with normal karyotype
    • Yu, M., Honoki, K., Anderson, J., Paietta, E., Nam, D.K. and Yunis, J.J. (1996) MLL tandem duplication and multiple splicing in acute myelogenous leukemia with normal karyotype. Leukemia 10, 774-780.
    • (1996) Leukemia , vol.10 , pp. 774-780
    • Yu, M.1    Honoki, K.2    Anderson, J.3    Paietta, E.4    Nam, D.K.5    Yunis, J.J.6
  • 37
    • 0028091804 scopus 로고
    • 11q23 translocations split the 'AT-hook' cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene
    • Zeleznik-Le, N.J., Harden, A.M. and Rowley, J.D. (1994) 11q23 translocations split the 'AT-hook' cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene. Proc. Natl. Acad. Sci. USA 91, 10610-10614.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10610-10614
    • Zeleznik-Le, N.J.1    Harden, A.M.2    Rowley, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.