Frequency of the Bcl-2/IgH rearrangement in normal individuals: Implications for the monitoring of disease in patients with follicular lymphoma

Journal of Clinical Oncology

Volumn 19, Issue 2, 2001, Pages 420-424

  Summers, K E ^a   Goff, L K ^a   Wilson, A G ^a   Gupta, R K ^a   Lister, T A ^a   Fitzgibbon, J ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; FEMALE; FOLLICULAR LYMPHOMA; GENE CLUSTER; GENE FREQUENCY; GENE REARRANGEMENT; HUMAN; MALE; MINIMAL RESIDUAL DISEASE; MONITORING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0035863493     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2001.19.2.420     Document Type: Article

References (22)

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3. Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma
4. Translocation (14;18)-positive cells are present in the circulation of the majority of patients with localized (stage I and II) follicular non-Hodgkin's lymphoma
5. Detection of occult lymphoma in the peripheral blood and bone marrow of patients with untreated early-stage and advanced-stage follicular lymphoma
6. All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment
7. Follicular lymphoma: Prognostic factors for response and survival
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17. Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes
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