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Volumn 20, Issue 5, 2015, Pages 722-729

Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?

Author keywords

chronic obstructive pulmonary disease; epithelial cell; immunity; inflammation; oxidative stress

Indexed keywords

CHEMOKINE; CYTOKINE; REACTIVE OXYGEN METABOLITE;

EID: 84931567493     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.12542     Document Type: Review
Times cited : (180)

References (69)
  • 2
    • 66149093072 scopus 로고    scopus 로고
    • The pathology of chronic obstructive pulmonary disease
    • Hogg JC, Timens W,. The pathology of chronic obstructive pulmonary disease. Annu. Rev. Pathol. 2009; 4: 435-459.
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 435-459
    • Hogg, J.C.1    Timens, W.2
  • 3
    • 0031862237 scopus 로고    scopus 로고
    • Number and proliferation of basal and parabasal cells in normal human airway epithelium
    • Boers JE, Ambergen AW, Thunnissen FB,. Number and proliferation of basal and parabasal cells in normal human airway epithelium. Am. J. Respir. Crit. Care Med. 1998; 157 (6 Pt 1): 2000-2006.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , Issue.6 , pp. 2000-2006
    • Boers, J.E.1    Ambergen, A.W.2    Thunnissen, F.B.3
  • 4
    • 1642269178 scopus 로고    scopus 로고
    • In vivo differentiation potential of tracheal basal cells: Evidence for multipotent and unipotent subpopulations
    • Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR,. In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am. J. Physiol. Lung Cell. Mol. Physiol. 2004; 286: L643-649.
    • (2004) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.286 , pp. L643-L649
    • Hong, K.U.1    Reynolds, S.D.2    Watkins, S.3    Fuchs, E.4    Stripp, B.R.5
  • 5
    • 0346888342 scopus 로고    scopus 로고
    • The airway epithelium: Structural and functional properties in health and disease
    • Knight DA, Holgate ST,. The airway epithelium: structural and functional properties in health and disease. Respirology 2003; 8: 432-446.
    • (2003) Respirology , vol.8 , pp. 432-446
    • Knight, D.A.1    Holgate, S.T.2
  • 6
    • 60849111087 scopus 로고    scopus 로고
    • Airway mucus: The good, the bad, the sticky
    • Evans CM, Koo JS,. Airway mucus: the good, the bad, the sticky. Pharmacol. Ther. 2009; 121: 332-348.
    • (2009) Pharmacol. Ther. , vol.121 , pp. 332-348
    • Evans, C.M.1    Koo, J.S.2
  • 8
  • 9
    • 60249095813 scopus 로고    scopus 로고
    • Mucins, mucus, and sputum
    • Voynow JA, Rubin BK,. Mucins, mucus, and sputum. Chest 2009; 135: 505-512.
    • (2009) Chest , vol.135 , pp. 505-512
    • Voynow, J.A.1    Rubin, B.K.2
  • 10
    • 84864561197 scopus 로고    scopus 로고
    • Epithelial cells, the 'switchboard' of respiratory immune defense responses: Effects of air pollutants
    • Müller L, Jaspers I,. Epithelial cells, the 'switchboard' of respiratory immune defense responses: effects of air pollutants. Swiss Med. Wkly 2012; 142: w13653.
    • (2012) Swiss Med. Wkly , vol.142 , pp. w13653
    • Müller, L.1    Jaspers, I.2
  • 14
    • 80052706801 scopus 로고    scopus 로고
    • New insights into the immunology of chronic obstructive pulmonary disease
    • Brusselle GG, Joos GF, Bracke KR,. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011; 378: 1015-1026.
    • (2011) Lancet , vol.378 , pp. 1015-1026
    • Brusselle, G.G.1    Joos, G.F.2    Bracke, K.R.3
  • 18
    • 66649127821 scopus 로고    scopus 로고
    • Immunologic aspects of chronic obstructive pulmonary disease
    • Cosio MG, Saetta M, Agusti A,. Immunologic aspects of chronic obstructive pulmonary disease. N. Engl. J. Med. 2009; 360: 2445-2454.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2445-2454
    • Cosio, M.G.1    Saetta, M.2    Agusti, A.3
  • 19
    • 0141928029 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
    • Barnes PJ, Shapiro SD, Pauwels RA,. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur. Respir. J. 2003; 22: 672-688.
    • (2003) Eur. Respir. J. , vol.22 , pp. 672-688
    • Barnes, P.J.1    Shapiro, S.D.2    Pauwels, R.A.3
  • 20
    • 77956340470 scopus 로고    scopus 로고
    • Involvement of type II pneumocytes in the pathogenesis of chronic obstructive pulmonary disease
    • Zhao CZ, Fang XC, Wang D, Tang FD, Wang XD,. Involvement of type II pneumocytes in the pathogenesis of chronic obstructive pulmonary disease. Respir. Med. 2010; 104: 1391-1395.
    • (2010) Respir. Med. , vol.104 , pp. 1391-1395
    • Zhao, C.Z.1    Fang, X.C.2    Wang, D.3    Tang, F.D.4    Wang, X.D.5
  • 23
    • 0033396197 scopus 로고    scopus 로고
    • Could the airway epithelium play an important role in mucosal IgA production?
    • Salvi S, Holgate ST,. Could the airway epithelium play an important role in mucosal IgA production? Clin. Exp. Allergy 1999; 29: 1597-1605.
    • (1999) Clin. Exp. Allergy , vol.29 , pp. 1597-1605
    • Salvi, S.1    Holgate, S.T.2
  • 25
    • 4344675455 scopus 로고    scopus 로고
    • Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
    • Hogg JC,. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004; 364: 709-721.
    • (2004) Lancet , vol.364 , pp. 709-721
    • Hogg, J.C.1
  • 26
    • 0242550746 scopus 로고    scopus 로고
    • Airway inflammation in chronic obstructive pulmonary disease: Comparisons with asthma
    • Sutherland ER, Martin RJ,. Airway inflammation in chronic obstructive pulmonary disease: comparisons with asthma. J. Allergy Clin. Immunol. 2003; 112: 819-827.
    • (2003) J. Allergy Clin. Immunol. , vol.112 , pp. 819-827
    • Sutherland, E.R.1    Martin, R.J.2
  • 27
    • 79953284970 scopus 로고    scopus 로고
    • Cigarette smoke modulates PGE(2) and host defence against Moraxella catarrhalis infection in human airway epithelial cells
    • Zhang W, Case S, Bowler RP, Martin RJ, Jiang D, Chu HW,. Cigarette smoke modulates PGE(2) and host defence against Moraxella catarrhalis infection in human airway epithelial cells. Respirology 2011; 16: 508-516.
    • (2011) Respirology , vol.16 , pp. 508-516
    • Zhang, W.1    Case, S.2    Bowler, R.P.3    Martin, R.J.4    Jiang, D.5    Chu, H.W.6
  • 28
    • 28444463303 scopus 로고    scopus 로고
    • Inflammatory mediators in chronic obstructive pulmonary disease
    • Chung KF,. Inflammatory mediators in chronic obstructive pulmonary disease. Curr. Drug Targets Inflamm. Allergy 2005; 4: 619-625.
    • (2005) Curr. Drug Targets Inflamm. Allergy , vol.4 , pp. 619-625
    • Chung, K.F.1
  • 30
    • 3342951748 scopus 로고    scopus 로고
    • Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling
    • Gray T, Nettesheim P, Loftin C, Koo JS, Bonner J, Peddada S, Langenbach R,. Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling. Mol. Pharmacol. 2004; 66: 337-346.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 337-346
    • Gray, T.1    Nettesheim, P.2    Loftin, C.3    Koo, J.S.4    Bonner, J.5    Peddada, S.6    Langenbach, R.7
  • 32
    • 0031788589 scopus 로고    scopus 로고
    • The role of reactive oxygen and nitrogen species in airway epithelial gene expression
    • Martin LD, Krunkosky TM, Voynow JA, Adler KB,. The role of reactive oxygen and nitrogen species in airway epithelial gene expression. Environ. Health Perspect. 1998; 106 (Suppl.): 1197-1203.
    • (1998) Environ. Health Perspect. , vol.106 , pp. 1197-1203
    • Martin, L.D.1    Krunkosky, T.M.2    Voynow, J.A.3    Adler, K.B.4
  • 33
    • 63449124229 scopus 로고    scopus 로고
    • Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution
    • Ovrevik J, Lag M, Holme JA, Schwarze PE, Refsnes M,. Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution. Toxicology 2009; 259: 46-53.
    • (2009) Toxicology , vol.259 , pp. 46-53
    • Ovrevik, J.1    Lag, M.2    Holme, J.A.3    Schwarze, P.E.4    Refsnes, M.5
  • 34
    • 84894269176 scopus 로고    scopus 로고
    • Glucosamine attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling
    • Wu YL, Lin AH, Chen CH, Huang WC, Wang HY, Liu MH, Lee TS, Ru Kou Y,. Glucosamine attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling. Free Radic. Biol. Med. 2014; 69: 208-218.
    • (2014) Free Radic. Biol. Med. , vol.69 , pp. 208-218
    • Wu, Y.L.1    Lin, A.H.2    Chen, C.H.3    Huang, W.C.4    Wang, H.Y.5    Liu, M.H.6    Lee, T.S.7    Ru Kou, Y.8
  • 35
    • 77952952508 scopus 로고    scopus 로고
    • Protein kinase ck2-mediated phosphorylation of hdac2 regulates co-repressor formation, deacetylase activity and acetylation of hdac2 by cigarette smoke and aldehydes
    • Adenuga D, Rahman I,. Protein kinase ck2-mediated phosphorylation of hdac2 regulates co-repressor formation, deacetylase activity and acetylation of hdac2 by cigarette smoke and aldehydes. Arch. Biochem. Biophys. 2010; 498: 62-73.
    • (2010) Arch. Biochem. Biophys. , vol.498 , pp. 62-73
    • Adenuga, D.1    Rahman, I.2
  • 40
    • 84925484650 scopus 로고    scopus 로고
    • Protective effects of sesaminol on BEAS-2B cells impaired by cigarette smoke extract
    • Dong P, Fu X, Wang X, Wang WM, Cao WM, Zhang WY,. Protective effects of sesaminol on BEAS-2B cells impaired by cigarette smoke extract. Cell Biochem. Biophys. 2015; 71: 1207-1213.
    • (2015) Cell Biochem. Biophys. , vol.71 , pp. 1207-1213
    • Dong, P.1    Fu, X.2    Wang, X.3    Wang, W.M.4    Cao, W.M.5    Zhang, W.Y.6
  • 41
    • 84896752943 scopus 로고    scopus 로고
    • Down-regulated peroxisome proliferator-activated receptor γ (PPARγ) in lung epithelial cells promotes a PPARγ agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD)
    • Lakshmi SP, Reddy AT, Zhang Y, Sciurba FC, Mallampalli RK, Duncan SR, Reddy RC,. Down-regulated peroxisome proliferator-activated receptor γ (PPARγ) in lung epithelial cells promotes a PPARγ agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD). J. Biol. Chem. 2014; 289: 6383-6393.
    • (2014) J. Biol. Chem. , vol.289 , pp. 6383-6393
    • Lakshmi, S.P.1    Reddy, A.T.2    Zhang, Y.3    Sciurba, F.C.4    Mallampalli, R.K.5    Duncan, S.R.6    Reddy, R.C.7
  • 42
    • 61549095273 scopus 로고    scopus 로고
    • Hyaluronan fragments/CD44 mediate oxidative stress-induced MUC5B up-regulation in airway epithelium
    • Casalino-Matsuda SM, Monzon ME, Day AJ, Forteza RM,. Hyaluronan fragments/CD44 mediate oxidative stress-induced MUC5B up-regulation in airway epithelium. Am. J. Respir. Cell Mol. Biol. 2009; 40: 277-285.
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.40 , pp. 277-285
    • Casalino-Matsuda, S.M.1    Monzon, M.E.2    Day, A.J.3    Forteza, R.M.4
  • 44
    • 77956631799 scopus 로고    scopus 로고
    • Lung injury and cancer: Mechanistic insights into ceramide and EGFR signaling under cigarette smoke
    • Goldkorn T, Filosto S,. Lung injury and cancer: mechanistic insights into ceramide and EGFR signaling under cigarette smoke. Am. J. Respir. Cell Mol. Biol. 2010; 43: 259-268.
    • (2010) Am. J. Respir. Cell Mol. Biol. , vol.43 , pp. 259-268
    • Goldkorn, T.1    Filosto, S.2
  • 45
    • 0032160553 scopus 로고    scopus 로고
    • Ozone alters distribution of β1 integrins in cultured primate bronchial epithelial cells
    • Jabbour AJ, Altman LC, Wight TN, Luchtel DL,. Ozone alters distribution of β1 integrins in cultured primate bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 1998; 19: 357-365.
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.19 , pp. 357-365
    • Jabbour, A.J.1    Altman, L.C.2    Wight, T.N.3    Luchtel, D.L.4
  • 47
    • 0035161960 scopus 로고    scopus 로고
    • Extracellular glutathione peroxidase induction in asthmatic lungs: Evidence for redox regulation of expression in human airway epithelial cells
    • Comhair SA, Bhathena PR, Farver C, Thunnissen FB, Erzurum SC,. Extracellular glutathione peroxidase induction in asthmatic lungs: evidence for redox regulation of expression in human airway epithelial cells. FASEB J. 2001; 15: 70-78.
    • (2001) FASEB J. , vol.15 , pp. 70-78
    • Comhair, S.A.1    Bhathena, P.R.2    Farver, C.3    Thunnissen, F.B.4    Erzurum, S.C.5
  • 48
    • 84899484406 scopus 로고    scopus 로고
    • Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: The materialization of the hormesis concept
    • Sthijns MM, Randall MJ, Bast A, Haenen GR,. Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: the materialization of the hormesis concept. Biochem. Biophys. Res. Commun. 2014; 446: 1029-1034.
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 1029-1034
    • Sthijns, M.M.1    Randall, M.J.2    Bast, A.3    Haenen, G.R.4
  • 49
    • 0033785188 scopus 로고    scopus 로고
    • Effect of cigarette smoke on the permeability and IL-1beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease
    • Rusznak C, Mills PR, Devalia JL, Sapsford RJ, Davies RJ, Lozewicz S,. Effect of cigarette smoke on the permeability and IL-1beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease. Am. J. Respir. Cell Mol. Biol. 2000; 23: 530-536.
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.23 , pp. 530-536
    • Rusznak, C.1    Mills, P.R.2    Devalia, J.L.3    Sapsford, R.J.4    Davies, R.J.5    Lozewicz, S.6
  • 51
    • 43549093774 scopus 로고    scopus 로고
    • Structure and function of the polymeric mucins in airways mucus
    • Thornton DJ, Rousseau K, McGuckin MA,. Structure and function of the polymeric mucins in airways mucus. Annu. Rev. Physiol. 2008; 70: 459-486.
    • (2008) Annu. Rev. Physiol. , vol.70 , pp. 459-486
    • Thornton, D.J.1    Rousseau, K.2    McGuckin, M.A.3
  • 52
    • 33750069111 scopus 로고    scopus 로고
    • Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction
    • Innes A, Woodruff P, Ferrando R, Donnelly S, Dolganov GM, Lazarus SC, Fahy JV,. Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction. Chest 2006; 130: 1102-1108.
    • (2006) Chest , vol.130 , pp. 1102-1108
    • Innes, A.1    Woodruff, P.2    Ferrando, R.3    Donnelly, S.4    Dolganov, G.M.5    Lazarus, S.C.6    Fahy, J.V.7
  • 53
    • 77955435635 scopus 로고    scopus 로고
    • New pharmacotherapy for airway mucus hypersecretion in asthma and COPD: Targeting intracellular signaling pathways
    • Lai H, Rogers DF,. New pharmacotherapy for airway mucus hypersecretion in asthma and COPD: targeting intracellular signaling pathways. J. Aerosol. Med. Pulm. Drug. Deliv. 2010; 23: 219-231.
    • (2010) J. Aerosol. Med. Pulm. Drug. Deliv. , vol.23 , pp. 219-231
    • Lai, H.1    Rogers, D.F.2
  • 55
    • 3342951748 scopus 로고    scopus 로고
    • Interleukin-1b-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling
    • Gray T, Nettesheim P, Loftin C, Koo JS, Bonner J, Peddada S, Langenbach R,. Interleukin-1b-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling. Mol. Pharmacol. 2004; 66: 337-346.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 337-346
    • Gray, T.1    Nettesheim, P.2    Loftin, C.3    Koo, J.S.4    Bonner, J.5    Peddada, S.6    Langenbach, R.7
  • 57
    • 79251595271 scopus 로고    scopus 로고
    • Arylhydrocarbon receptor (AhR) activation in airway epithelial cells induces MUC5AC via reactive oxygen species (ROS) production
    • Chiba T, Uchi H, Tsuji G, Gondo H, Moroi Y, Furue M,. Arylhydrocarbon receptor (AhR) activation in airway epithelial cells induces MUC5AC via reactive oxygen species (ROS) production. Pulm. Pharmacol. Ther. 2011; 24: 133-140.
    • (2011) Pulm. Pharmacol. Ther. , vol.24 , pp. 133-140
    • Chiba, T.1    Uchi, H.2    Tsuji, G.3    Gondo, H.4    Moroi, Y.5    Furue, M.6
  • 58
    • 84864455356 scopus 로고    scopus 로고
    • The effect of quercetin on human neutrophil elastase-induced mucin5AC expression in human airway epithelial cells
    • Li N, Li Q, Zhou XD, Kolosov VP, Perelman JM,. The effect of quercetin on human neutrophil elastase-induced mucin5AC expression in human airway epithelial cells. Int. Immunopharmacol. 2012; 14: 195-201.
    • (2012) Int. Immunopharmacol. , vol.14 , pp. 195-201
    • Li, N.1    Li, Q.2    Zhou, X.D.3    Kolosov, V.P.4    Perelman, J.M.5
  • 61
    • 11144221941 scopus 로고    scopus 로고
    • Relationship of airway epithelial ion transport to chronic bronchitis
    • Boucher RC,. Relationship of airway epithelial ion transport to chronic bronchitis. Proc. Am. Thorac. Soc. 2004; 1: 66-70.
    • (2004) Proc. Am. Thorac. Soc. , vol.1 , pp. 66-70
    • Boucher, R.C.1
  • 63
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA,. The basics of epithelial-mesenchymal transition. J. Clin. Invest. 2009; 119: 1420-1428.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 64
    • 67349130377 scopus 로고    scopus 로고
    • TGF-beta1 induces human bronchial epithelial cell-tomesenchymal transition in vitro
    • Zhang M, Zhang Z, Pan HY, Wang DX, Deng ZT, Ye XL,. TGF-beta1 induces human bronchial epithelial cell-tomesenchymal transition in vitro. Lung 2009; 187: 187-194.
    • (2009) Lung , vol.187 , pp. 187-194
    • Zhang, M.1    Zhang, Z.2    Pan, H.Y.3    Wang, D.X.4    Deng, Z.T.5    Ye, X.L.6
  • 65
    • 77954919917 scopus 로고    scopus 로고
    • Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease
    • Sohal SS, Reid D, Soltani A, Ward C, Weston S, Muller HK, Wood-Baker R, Walters EH,. Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease. Respirology 2010; 15: 930-938.
    • (2010) Respirology , vol.15 , pp. 930-938
    • Sohal, S.S.1    Reid, D.2    Soltani, A.3    Ward, C.4    Weston, S.5    Muller, H.K.6    Wood-Baker, R.7    Walters, E.H.8
  • 66
    • 33751234251 scopus 로고    scopus 로고
    • Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease
    • Puchelle E, Zahm JM, Tournier JM, Coraux C,. Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2006; 3: 726-733.
    • (2006) Proc. Am. Thorac. Soc. , vol.3 , pp. 726-733
    • Puchelle, E.1    Zahm, J.M.2    Tournier, J.M.3    Coraux, C.4
  • 68
    • 33751344423 scopus 로고    scopus 로고
    • Tissue remodeling and repair mechanisms in chronic obstructive pulmonary disease
    • Leff AR,. Tissue remodeling and repair mechanisms in chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2006; 3: 734-736.
    • (2006) Proc. Am. Thorac. Soc. , vol.3 , pp. 734-736
    • Leff, A.R.1


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