Early Drug Discovery Prediction of Proarrhythmia Potential and Its Covariates

AAPS Journal

Volumn 17, Issue 4, 2015, Pages 1025-1032

  Polak, Sebastian ^b,c   Pugsley, Michael K ^d   Stockbridge, Norman ^e   Garnett, Christine ^a   Wiśniowska, Barbara ^c  

^a CERTARA   (United States)

^b CERTARA UK LIMITED   (United Kingdom)

^c JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^d JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^e CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CISAPRIDE; TRIMEBUTINE;

ARTICLE; CALCIUM TRANSPORT; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG SAFETY; HEART CONDUCTION; HEART DEPOLARIZATION; HEART PROARRHYTHMIA; HEART REPOLARIZATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR PATHOLOGY; PREDICTION; QT INTERVAL; ANIMAL; CARDIOTOXICITY; CHEMICALLY INDUCED; DRUG DESIGN; DRUG DEVELOPMENT; HEART ARRHYTHMIA; PROCEDURES;

ANIMALS; ARRHYTHMIAS, CARDIAC; CARDIOTOXICITY; DRUG DESIGN; DRUG DISCOVERY; HUMANS;

EID: 84931561084     PISSN: None     EISSN: 15507416     Source Type: Journal    
DOI: 10.1208/s12248-015-9773-1     Document Type: Article

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