메뉴 건너뛰기




Volumn 290, Issue 26, 2015, Pages 16319-16329

Regulation of ERK kinase by MEK1 kinase inhibition in the brain

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CHEMICAL ACTIVATION; ENZYMES; FEEDBACK; MAMMALS; PROTEINS; SIGNAL TRANSDUCTION;

EID: 84931285081     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.654897     Document Type: Article
Times cited : (18)

References (79)
  • 2
    • 0033694754 scopus 로고    scopus 로고
    • The TrkBShc site signals neuronal survival and local axon growth via MEK and P13-kinase
    • Atwal, J. K., Massie, B., Miller, F. D., and Kaplan, D. R. (2000) The TrkBShc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron 27, 265-277
    • (2000) Neuron , vol.27 , pp. 265-277
    • Atwal, J.K.1    Massie, B.2    Miller, F.D.3    Kaplan, D.R.4
  • 3
    • 84896926741 scopus 로고    scopus 로고
    • Ras protein activation is a key event in activity-dependent survival of cerebellar granule neurons
    • Xifró, X., Miñano-Molina, A. J., Saura, C. A., and Rodríguez-Álvarez, J. (2014) Ras protein activation is a key event in activity-dependent survival of cerebellar granule neurons. J. Biol. Chem. 289, 8462-8472
    • (2014) J. Biol. Chem. , vol.289 , pp. 8462-8472
    • Xifró, X.1    Miñano-Molina, A.J.2    Saura, C.A.3    Rodríguez-Álvarez, J.4
  • 4
    • 0345579566 scopus 로고    scopus 로고
    • Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation
    • English, J. D., and Sweatt, J. D. (1996) Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation. J. Biol. Chem. 271, 24329-24332
    • (1996) J. Biol. Chem. , vol.271 , pp. 24329-24332
    • English, J.D.1    Sweatt, J.D.2
  • 5
    • 0025813396 scopus 로고
    • Stimulation of protein tyrosine phosphorylation by NMDA receptor activation
    • Bading, H., and Greenberg, M. E. (1991) Stimulation of protein tyrosine phosphorylation by NMDA receptor activation. Science 253, 912-914
    • (1991) Science , vol.253 , pp. 912-914
    • Bading, H.1    Greenberg, M.E.2
  • 6
    • 0038113070 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase in hippocampal circuitry is required for consolidation and reconsolidation of recognition memory
    • Kelly, A., Laroche, S., and Davis, S. (2003) Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase in hippocampal circuitry is required for consolidation and reconsolidation of recognition memory. J. Neurosci. 23, 5354-5360
    • (2003) J. Neurosci. , vol.23 , pp. 5354-5360
    • Kelly, A.1    Laroche, S.2    Davis, S.3
  • 7
    • 0032944350 scopus 로고    scopus 로고
    • Memory consolidation for contextual and auditory fear conditioning is dependent on protein synthesis, PKA, and MAPkinase
    • Schafe, G. E., Nadel, N. V., Sullivan, G. M., Harris, A., and Le Doux, J. E. (1999) Memory consolidation for contextual and auditory fear conditioning is dependent on protein synthesis, PKA, and MAPkinase. Learn. Mem. 6, 97-110
    • (1999) Learn. Mem. , vol.6 , pp. 97-110
    • Schafe, G.E.1    Nadel, N.V.2    Sullivan, G.M.3    Harris, A.4    Le Doux, J.E.5
  • 8
    • 0034331242 scopus 로고    scopus 로고
    • Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of Pavlovian fear conditioning
    • Schafe, G. E., Atkins, C. M., Swank, M. W., Bauer, E. P., Sweatt, J. D., and Le Doux, J. E. (2000) Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of Pavlovian fear conditioning. J. Neurosci. 20, 8177-8187
    • (2000) J. Neurosci. , vol.20 , pp. 8177-8187
    • Schafe, G.E.1    Atkins, C.M.2    Swank, M.W.3    Bauer, E.P.4    Sweatt, J.D.5    Le Doux, J.E.6
  • 9
    • 0032725305 scopus 로고    scopus 로고
    • A necessity for MAP kinase activation in mammalian spatial learning
    • Selcher, J. C., Atkins, C. M., Trzaskos, J. M., Paylor, R., and Sweatt, J. D. (1999) A necessity for MAP kinase activation in mammalian spatial learning. Learn. Mem. 6, 478-490
    • (1999) Learn. Mem. , vol.6 , pp. 478-490
    • Selcher, J.C.1    Atkins, C.M.2    Trzaskos, J.M.3    Paylor, R.4    Sweatt, J.D.5
  • 10
    • 0033936313 scopus 로고    scopus 로고
    • Increased levels of transcription factors Elk-1, cyclic adenosine monophosphate response element-binding protein, and activating transcription factor 2 in the cerebellar vermis of schizophrenic patients
    • Kyosseva, S. V., Elbein, A. D., Hutton, T. L., Griffin, S. T., Mrak, R. E., Sturner, W. Q., and Karson, C. N. (2000) Increased levels of transcription factors Elk-1, cyclic adenosine monophosphate response element-binding protein, and activating transcription factor 2 in the cerebellar vermis of schizophrenic patients. Arch. Gen. Psychiatry 57, 685-691
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 685-691
    • Kyosseva, S.V.1    Elbein, A.D.2    Hutton, T.L.3    Griffin, S.T.4    Mrak, R.E.5    Sturner, W.Q.6    Karson, C.N.7
  • 12
    • 0041884818 scopus 로고    scopus 로고
    • Increased expression of c-Jun. Transcription factor in cerebellar vermis of patients with schizophrenia
    • Todorova, V. K., Elbein, A. D., and Kyosseva, S. V. (2003) Increased expression of c-Jun. transcription factor in cerebellar vermis of patients with schizophrenia. Neuropsychopharmacology 28, 1506-1514
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1506-1514
    • Todorova, V.K.1    Elbein, A.D.2    Kyosseva, S.V.3
  • 13
    • 0035020808 scopus 로고    scopus 로고
    • Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects
    • Dwivedi, Y., Rizavi, H. S., Roberts, R. C., Conley, R. C., Tamminga, C. A., and Pandey, G. N. (2001) Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects. J. Neurochem. 77, 916-928
    • (2001) J. Neurochem. , vol.77 , pp. 916-928
    • Dwivedi, Y.1    Rizavi, H.S.2    Roberts, R.C.3    Conley, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 14
    • 84887103262 scopus 로고    scopus 로고
    • Antidepressant-like activity of resveratrol treatment in the forced swim test and tail suspension test in mice: The HPA axis, BDNF expression and phosphorylation of ERK
    • Wang, Z., Gu, J., Wang, X., Xie, K., Luan, Q., Wan, N., Zhang, Q., Jiang, H., and Liu, D. (2013) Antidepressant-like activity of resveratrol treatment in the forced swim test and tail suspension test in mice: the HPA axis, BDNF expression and phosphorylation of ERK. Pharmacol. Biochem. Behav. 112, 104-110
    • (2013) Pharmacol. Biochem. Behav. , vol.112 , pp. 104-110
    • Wang, Z.1    Gu, J.2    Wang, X.3    Xie, K.4    Luan, Q.5    Wan, N.6    Zhang, Q.7    Jiang, H.8    Liu, D.9
  • 15
    • 33847308098 scopus 로고    scopus 로고
    • A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment
    • Duman, C. H., Schlesinger, L., Kodama, M., Russell, D. S., and Duman, R. S. (2007) A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol. psychiatry 61, 661-670
    • (2007) Biol. Psychiatry , vol.61 , pp. 661-670
    • Duman, C.H.1    Schlesinger, L.2    Kodama, M.3    Russell, D.S.4    Duman, R.S.5
  • 16
    • 33750014180 scopus 로고    scopus 로고
    • Role of amygdala MAPK activation on immobility behavior of forced swim rats
    • Huang, T. Y., and Lin, C. H. (2006) Role of amygdala MAPK activation on immobility behavior of forced swim rats. Behav. Brain Res. 173, 104-111
    • (2006) Behav. Brain Res. , vol.173 , pp. 104-111
    • Huang, T.Y.1    Lin, C.H.2
  • 17
    • 61349105329 scopus 로고    scopus 로고
    • A role for the extracellular signal-regulated kinase signal pathway in depressive-like behavior
    • Qi, X., Lin, W., Wang, D., Pan, Y., Wang, W., and Sun, M. (2009) A role for the extracellular signal-regulated kinase signal pathway in depressive-like behavior. Behav. Brain Res. 199, 203-209
    • (2009) Behav. Brain Res. , vol.199 , pp. 203-209
    • Qi, X.1    Lin, W.2    Wang, D.3    Pan, Y.4    Wang, W.5    Sun, M.6
  • 18
    • 33750994069 scopus 로고    scopus 로고
    • The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress
    • Qi, X., Lin, W., Li, J., Pan, Y., and Wang, W. (2006) The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress. Behav. Brain Res. 175, 233-240
    • (2006) Behav. Brain Res. , vol.175 , pp. 233-240
    • Qi, X.1    Lin, W.2    Li, J.3    Pan, Y.4    Wang, W.5
  • 19
    • 47149097819 scopus 로고    scopus 로고
    • Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress
    • Qi, X., Lin, W., Li, J., Li, H., Wang, W., Wang, D., and Sun, M. (2008) Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiol. Dis. 31, 278-285
    • (2008) Neurobiol. Dis. , vol.31 , pp. 278-285
    • Qi, X.1    Lin, W.2    Li, J.3    Li, H.4    Wang, W.5    Wang, D.6    Sun, M.7
  • 20
    • 0034548879 scopus 로고    scopus 로고
    • Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties
    • Valjent, E., Corvol, J. C., Pages, C., Besson, M. J., Maldonado, R., and Caboche, J. (2000) Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties. J. Neurosci. 20, 8701-8709
    • (2000) J. Neurosci. , vol.20 , pp. 8701-8709
    • Valjent, E.1    Corvol, J.C.2    Pages, C.3    Besson, M.J.4    Maldonado, R.5    Caboche, J.6
  • 22
    • 0037096396 scopus 로고    scopus 로고
    • Protein kinase modulation of dendritic K+ channels in hippocampus involves a mitogen-activated protein kinase pathway
    • Yuan, L. L., Adams, J. P., Swank, M., Sweatt, J. D., and Johnston, D. (2002) Protein kinase modulation of dendritic K+ channels in hippocampus involves a mitogen-activated protein kinase pathway. J. Neurosci. 22, 4860-4868
    • (2002) J. Neurosci. , vol.22 , pp. 4860-4868
    • Yuan, L.L.1    Adams, J.P.2    Swank, M.3    Sweatt, J.D.4    Johnston, D.5
  • 24
    • 84900554576 scopus 로고    scopus 로고
    • Long-term memory deficits are associated with elevated synaptic ERK1/2 activation and reversed by mGluR5 antagonism in an animal model of autism
    • Seese, R. R., Maske, A. R., Lynch, G., and Gall, C. M. (2014) Long-term memory deficits are associated with elevated synaptic ERK1/2 activation and reversed by mGluR5 antagonism in an animal model of autism. Neuropsychopharmacology 39, 1664-1673
    • (2014) Neuropsychopharmacology , vol.39 , pp. 1664-1673
    • Seese, R.R.1    Maske, A.R.2    Lynch, G.3    Gall, C.M.4
  • 26
    • 41949135731 scopus 로고    scopus 로고
    • Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome
    • Kim, S. H., Markham, J. A., Weiler, I. J., and Greenough, W. T. (2008) Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome. Proc. Natl. Acad. Sci. U. S. A. 105, 4429-4434
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 4429-4434
    • Kim, S.H.1    Markham, J.A.2    Weiler, I.J.3    Greenough, W.T.4
  • 28
    • 0028277844 scopus 로고
    • Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras
    • Rosen, L. B., Ginty, D. D., Weber, M. J., and Greenberg, M. E. (1994) Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 12, 1207-1221
    • (1994) Neuron , vol.12 , pp. 1207-1221
    • Rosen, L.B.1    Ginty, D.D.2    Weber, M.J.3    Greenberg, M.E.4
  • 29
    • 0030908089 scopus 로고    scopus 로고
    • MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia
    • Martin, K. C., Michael, D., Rose, J. C., Barad, M., Casadio, A., Zhu, H., and Kandel, E. R. (1997) MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia. Neuron 18, 899-912
    • (1997) Neuron , vol.18 , pp. 899-912
    • Martin, K.C.1    Michael, D.2    Rose, J.C.3    Barad, M.4    Casadio, A.5    Zhu, H.6    Kandel, E.R.7
  • 30
    • 0030963439 scopus 로고    scopus 로고
    • cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
    • Vossler, M. R., Yao, H., York, R. D., Pan, M. G., Rim, C. S., and Stork, P. J. (1997) cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 89, 73-82
    • (1997) Cell , vol.89 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.G.4    Rim, C.S.5    Stork, P.J.6
  • 31
    • 0032499282 scopus 로고    scopus 로고
    • Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
    • York, R. D., Yao, H., Dillon, T., Ellig, C. L., Eckert, S. P., McCleskey, E. W., and Stork, P. J. (1998) Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature 392, 622-626
    • (1998) Nature , vol.392 , pp. 622-626
    • York, R.D.1    Yao, H.2    Dillon, T.3    Ellig, C.L.4    Eckert, S.P.5    McCleskey, E.W.6    Stork, P.J.7
  • 32
    • 0032478715 scopus 로고    scopus 로고
    • The cyclic adenosine monophosphate-dependent protein kinase (PKA) is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factor
    • Yao, H., York, R. D., Misra-Press, A., Carr, D. W., and Stork, P. J. (1998) The cyclic adenosine monophosphate-dependent protein kinase (PKA) is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factor. J. Biol. Chem. 273, 8240-8247
    • (1998) J. Biol. Chem. , vol.273 , pp. 8240-8247
    • Yao, H.1    York, R.D.2    Misra-Press, A.3    Carr, D.W.4    Stork, P.J.5
  • 33
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal, R. A., and Greenberg, M. E. (1996) Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci. 19, 463-489
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 35
    • 0028297817 scopus 로고
    • MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: Analysis of phosphopeptides and regulation of activity
    • Gardner, A. M., Vaillancourt, R. R., Lange-Carter, C. A., and Johnson, G. L. (1994) MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity. Mol. Biol. Cell 5, 193-201
    • (1994) Mol. Biol. Cell , vol.5 , pp. 193-201
    • Gardner, A.M.1    Vaillancourt, R.R.2    Lange-Carter, C.A.3    Johnson, G.L.4
  • 36
    • 1542284071 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion
    • Eblen, S. T., Slack-Davis, J. K., Tarcsafalvi, A., Parsons, J. T., Weber, M. J., and Catling, A. D. (2004) Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion. Mol. Cell. Biol. 24, 2308-2317
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 2308-2317
    • Eblen, S.T.1    Slack-Davis, J.K.2    Tarcsafalvi, A.3    Parsons, J.T.4    Weber, M.J.5    Catling, A.D.6
  • 38
    • 0028219853 scopus 로고
    • Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation
    • Rossomando, A. J., Dent, P., Sturgill, T. W., and Marshak, D. R. (1994) Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation. Mol. Cell. Biol. 14, 1594-1602
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1594-1602
    • Rossomando, A.J.1    Dent, P.2    Sturgill, T.W.3    Marshak, D.R.4
  • 39
  • 40
    • 34248592288 scopus 로고    scopus 로고
    • Cyclin dependent kinase 5 (Cdk5) mediated inhibition of the MAP kinase pathway results in CREB down regulation and apoptosis in PC12 cells
    • Sharma, M., Hanchate, N. K., Tyagi, R. K., and Sharma, P. (2007) Cyclin dependent kinase 5 (Cdk5) mediated inhibition of the MAP kinase pathway results in CREB down regulation and apoptosis in PC12 cells. Biochem. Biophys. Res. Commun. 358, 379-384
    • (2007) Biochem. Biophys. Res. Commun. , vol.358 , pp. 379-384
    • Sharma, M.1    Hanchate, N.K.2    Tyagi, R.K.3    Sharma, P.4
  • 44
    • 27144531077 scopus 로고    scopus 로고
    • Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons
    • Hamada, M., Hendrick, J. P., Ryan, G. R., Kuroiwa, M., Higashi, H., Tanaka, M., Nairn, A. C., Greengard, P., and Nishi, A. (2005) Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons. J. Pharmacol. Exp. Ther. 315, 872-878
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 872-878
    • Hamada, M.1    Hendrick, J.P.2    Ryan, G.R.3    Kuroiwa, M.4    Higashi, H.5    Tanaka, M.6    Nairn, A.C.7    Greengard, P.8    Nishi, A.9
  • 48
    • 0028276218 scopus 로고
    • Growth factor-stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1)
    • Brunet, A., Pagès, G., and Pouysségur, J. (1994) Growth factor-stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1). FEBS Lett. 346, 299-303
    • (1994) FEBS Lett. , vol.346 , pp. 299-303
    • Brunet, A.1    Pagès, G.2    Pouysségur, J.3
  • 49
    • 42449089351 scopus 로고    scopus 로고
    • Enzyme kinetics and binding studies on inhibitors of MEK protein kinase
    • Van Scyoc, W. S., Holdgate, G. A., Sullivan, J. E., and Ward, W. H. (2008) Enzyme kinetics and binding studies on inhibitors of MEK protein kinase. Biochemistry 47, 5017-5027
    • (2008) Biochemistry , vol.47 , pp. 5017-5027
    • Van Scyoc, W.S.1    Holdgate, G.A.2    Sullivan, J.E.3    Ward, W.H.4
  • 52
    • 84857743613 scopus 로고    scopus 로고
    • Mechanisms for the modulation of dopamine d (1) receptor signaling in striatal neurons
    • Nishi, A., Kuroiwa, M., and Shuto, T. (2011) Mechanisms for the modulation of dopamine d (1) receptor signaling in striatal neurons. Front. Neuroanat. 5, 43
    • (2011) Front. Neuroanat. , vol.5 , pp. 43
    • Nishi, A.1    Kuroiwa, M.2    Shuto, T.3
  • 54
    • 79960221972 scopus 로고    scopus 로고
    • What is the degree of segregation between striatonigral and striatopallidal projections?
    • Bertran-Gonzalez, J., Herve, D., Girault, J. A., and Valjent, E. (2010) What is the degree of segregation between striatonigral and striatopallidal projections? Front. Neuroanat. 4, 136
    • (2010) Front. Neuroanat. , vol.4 , pp. 136
    • Bertran-Gonzalez, J.1    Herve, D.2    Girault, J.A.3    Valjent, E.4
  • 55
    • 0033010457 scopus 로고    scopus 로고
    • Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons
    • Nishi, A., Snyder, G. L., Nairn, A. C., and Greengard, P. (1999) Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons. J. Neurochem. 72, 2015-2021
    • (1999) J. Neurochem. , vol.72 , pp. 2015-2021
    • Nishi, A.1    Snyder, G.L.2    Nairn, A.C.3    Greengard, P.4
  • 57
    • 0037414762 scopus 로고    scopus 로고
    • Usage of tautomycetin, a novel inhibitor of protein phosphatase 1(PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo
    • Mitsuhashi, S., Shima, H., Tanuma, N., Matsuura, N., Takekawa, M., Urano, T., Kataoka, T., Ubukata, M., and Kikuchi, K. (2003) Usage of tautomycetin, a novel inhibitor of protein phosphatase 1(PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo. J. Biol. Chem. 278, 82-88
    • (2003) J. Biol. Chem. , vol.278 , pp. 82-88
    • Mitsuhashi, S.1    Shima, H.2    Tanuma, N.3    Matsuura, N.4    Takekawa, M.5    Urano, T.6    Kataoka, T.7    Ubukata, M.8    Kikuchi, K.9
  • 58
    • 4744352601 scopus 로고    scopus 로고
    • Protein phosphatase 2A, a negative regulator of the ERK signaling pathway, is activated by tyrosine phosphorylation of putative HLA class II-associated protein I (PHAPI)/pp32 in response to the antiproliferative lectin, jacalin
    • Yu, L. G., Packman, L. C., Weldon, M., Hamlett, J., and Rhodes, J. M. (2004) Protein phosphatase 2A, a negative regulator of the ERK signaling pathway, is activated by tyrosine phosphorylation of putative HLA class II-associated protein I (PHAPI)/pp32 in response to the antiproliferative lectin, jacalin. J. Biol. Chem. 279, 41377-41383
    • (2004) J. Biol. Chem. , vol.279 , pp. 41377-41383
    • Yu, L.G.1    Packman, L.C.2    Weldon, M.3    Hamlett, J.4    Rhodes, J.M.5
  • 59
    • 0032078872 scopus 로고    scopus 로고
    • A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II
    • Chen, H. J., Rojas-Soto, M., Oguni, A., and Kennedy, M. B. (1998) A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II. Neuron 20, 895-904
    • (1998) Neuron , vol.20 , pp. 895-904
    • Chen, H.J.1    Rojas-Soto, M.2    Oguni, A.3    Kennedy, M.B.4
  • 61
    • 84855966123 scopus 로고    scopus 로고
    • NMDA-induced ERK signalling is mediated by NR2B subunit in rat cortical neurons and switches from positive to negative depending on stage of development
    • Sava, A., Formaggio, E., Carignani, C., Andreetta, F., Bettini, E., and Griffante, C. (2012) NMDA-induced ERK signalling is mediated by NR2B subunit in rat cortical neurons and switches from positive to negative depending on stage of development. Neuropharmacology 62, 925-932
    • (2012) Neuropharmacology , vol.62 , pp. 925-932
    • Sava, A.1    Formaggio, E.2    Carignani, C.3    Andreetta, F.4    Bettini, E.5    Griffante, C.6
  • 62
    • 0033639083 scopus 로고    scopus 로고
    • Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting
    • Ehlers, M. D. (2000) Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron 28, 511-525
    • (2000) Neuron , vol.28 , pp. 511-525
    • Ehlers, M.D.1
  • 63
    • 0032215153 scopus 로고    scopus 로고
    • Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression
    • Kameyama, K., Lee, H. K., Bear, M. F., and Huganir, R. L. (1998) Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression. Neuron 21, 1163-1175
    • (1998) Neuron , vol.21 , pp. 1163-1175
    • Kameyama, K.1    Lee, H.K.2    Bear, M.F.3    Huganir, R.L.4
  • 66
    • 0028919711 scopus 로고
    • Stress-induced sensitization and facilitated learning require NMDA receptor activation
    • Shors, T. J., and Servatius, R. J. (1995) Stress-induced sensitization and facilitated learning require NMDA receptor activation. Neuroreport 6, 677-680
    • (1995) Neuroreport , vol.6 , pp. 677-680
    • Shors, T.J.1    Servatius, R.J.2
  • 67
    • 79151475712 scopus 로고    scopus 로고
    • Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory
    • Yuen, E. Y., Liu, W., Karatsoreos, I. N., Ren, Y., Feng, J., McEwen, B. S., and Yan, Z. (2011) Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory. Mol. Psychiatry 16, 156-170
    • (2011) Mol. Psychiatry , vol.16 , pp. 156-170
    • Yuen, E.Y.1    Liu, W.2    Karatsoreos, I.N.3    Ren, Y.4    Feng, J.5    McEwen, B.S.6    Yan, Z.7
  • 68
    • 0018268297 scopus 로고
    • Behavioural despair in rats: A new model sensitive to antidepressant treatments
    • Porsolt, R. D., Anton, G., Blavet, N., and Jalfre, M. (1978) Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur. J. Pharmacol. 47, 379-391
    • (1978) Eur. J. Pharmacol. , vol.47 , pp. 379-391
    • Porsolt, R.D.1    Anton, G.2    Blavet, N.3    Jalfre, M.4
  • 69
    • 0036333485 scopus 로고    scopus 로고
    • Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes
    • Eblen, S. T., Slack, J. K., Weber, M. J., and Catling, A. D. (2002) Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes. Mol. Cell. Biol. 22, 6023-6033
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6023-6033
    • Eblen, S.T.1    Slack, J.K.2    Weber, M.J.3    Catling, A.D.4
  • 71
    • 0030830220 scopus 로고    scopus 로고
    • Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins
    • Frost, J. A., Steen, H., Shapiro, P., Lewis, T., Ahn, N., Shaw, P. E., and Cobb, M. H. (1997) Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins. EMBO J. 16, 6426-6438
    • (1997) EMBO J. , vol.16 , pp. 6426-6438
    • Frost, J.A.1    Steen, H.2    Shapiro, P.3    Lewis, T.4    Ahn, N.5    Shaw, P.E.6    Cobb, M.H.7
  • 72
    • 0037424509 scopus 로고    scopus 로고
    • Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1
    • Gopalbhai, K., Jansen, G., Beauregard, G., Whiteway, M., Dumas, F., Wu, C., and Meloche, S. (2003) Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1. J. Biol. Chem. 278, 8118-8125
    • (2003) J. Biol. Chem. , vol.278 , pp. 8118-8125
    • Gopalbhai, K.1    Jansen, G.2    Beauregard, G.3    Whiteway, M.4    Dumas, F.5    Wu, C.6    Meloche, S.7
  • 74
    • 0037220735 scopus 로고    scopus 로고
    • NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling
    • Paul, S., Nairn, A. C., Wang, P., and Lombroso, P. J. (2003) NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat. Neurosci. 6, 34-42
    • (2003) Nat. Neurosci. , vol.6 , pp. 34-42
    • Paul, S.1    Nairn, A.C.2    Wang, P.3    Lombroso, P.J.4
  • 75
    • 0032450662 scopus 로고    scopus 로고
    • NMDA receptor antagonism in the lateral/basolateral but not central nucleus of the amygdala prevents the induction of facilitated learning in response to stress
    • Shors, T. J., and Mathew, P. R. (1998) NMDA receptor antagonism in the lateral/basolateral but not central nucleus of the amygdala prevents the induction of facilitated learning in response to stress. Learn. Mem. 5, 220-230
    • (1998) Learn. Mem. , vol.5 , pp. 220-230
    • Shors, T.J.1    Mathew, P.R.2
  • 76
    • 0043240266 scopus 로고    scopus 로고
    • The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
    • Einat, H., Yuan, P., Gould, T. D., Li, J., Du, J., Zhang, L., Manji, H. K., and Chen, G. (2003) The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J. Neurosci. 23, 7311-7316
    • (2003) J. Neurosci. , vol.23 , pp. 7311-7316
    • Einat, H.1    Yuan, P.2    Gould, T.D.3    Li, J.4    Du, J.5    Zhang, L.6    Manji, H.K.7    Chen, G.8
  • 77
    • 64949121875 scopus 로고    scopus 로고
    • Suppression of the MEK/ERK signaling pathway reverses depressionlike behaviors of CRF2-deficient mice
    • Todorovic, C., Sherrin, T., Pitts, M., Hippel, C., Rayner, M., and Spiess, J. (2009) Suppression of the MEK/ERK signaling pathway reverses depressionlike behaviors of CRF2-deficient mice. Neuropsychopharmacology 34, 1416-1426
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1416-1426
    • Todorovic, C.1    Sherrin, T.2    Pitts, M.3    Hippel, C.4    Rayner, M.5    Spiess, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.