The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation

Nature Communications

Volumn 6, Issue , 2015, Pages

  Hernandez, Jeniffer B ^a   Chang, Christina ^a   Leblanc, Mathias ^a   Grimm, David ^a   Le Lay, John ^b   Kaestner, Klaus H ^b   Zheng, Ye ^a   Montminy, Marc ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 17F; PROSTAGLANDIN E2; CREB1 PROTEIN, MOUSE; CRTC2 PROTEIN, MOUSE; IL17A PROTEIN, MOUSE; IL17F PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

CELL ORGANELLE; IMMUNE RESPONSE; IMMUNITY; LIPID; RODENT;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CRTC2 GENE; GENE; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; MOUSE; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TH17 CELL; ANIMAL; BRAIN; DRUG EFFECTS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD; WESTERN BLOTTING;

MUS;

ANIMALS; BLOTTING, WESTERN; BRAIN; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DINOPROSTONE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HEK293 CELLS; HUMANS; INTERLEUKIN-17; LYMPHOCYTE ACTIVATION; MICE; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; SPINAL CORD; TH17 CELLS; TRANSCRIPTION FACTORS;

EID: 84931275719     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8216     Document Type: Article

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