DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection

International Immunology

Volumn 17, Issue 11, 2005, Pages 1379-1390

  Friedrich, Monica L ^a   Wen, Ben G ^b,c   Bain, Gretchen ^b   Kee, Barbara L ^b,d   Katayama, Carol ^b   Murre, Cornelis ^b   Hedrick, Stephen M ^b   Walsh, Craig M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

Central tolerance; DAP kinase; Positive selection; Signal transduction; T cells; Thymocytes

Indexed keywords

ANTIBODY; DAP RELATED APOPTOTIC KINASE 3; DEATH ASSOCIATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; RETROVIRUS VECTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOACCUMULATION; CALCIUM SIGNALING; CELL MATURATION; CELL SELECTION; CONTROLLED STUDY; FIBROBLAST; GENE ACTIVATION; GENETIC TRANSDUCTION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOID TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; SURVIVAL RATE; T LYMPHOCYTE; THYMOCYTE; THYMUS;

ANIMALS; APOPTOSIS; CALCIUM SIGNALING; CELL SURVIVAL; GENE EXPRESSION REGULATION; LYMPHOCYTE ACTIVATION; MICE; NIH 3T3 CELLS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; THYMUS GLAND;

EID: 27744540809     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxh315     Document Type: Article

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