-
1
-
-
84931286362
-
-
GeneTests Database. http://www.genetests.org.
-
-
-
-
2
-
-
84863556835
-
Evolution and functional impact of rare coding variation from deep sequencing of human exomes
-
Tennessen JA, Bigham AW, O'Connor TD, Fu W, Kenny EE, Gravel S, McGee S, Do R, Liu X, Jun G, Kang HM, Jordan D, Leal SM, Gabriel S, Rieder MJ, Abecasis G, Altshuler D, Nickerson DA, Boerwinkle E, Sunyaev S, Bustamante CD, Bamshad MJ, Akey JM: Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science 2012, 337:64-69.
-
(2012)
Science
, vol.337
, pp. 64-69
-
-
Tennessen, J.A.1
Bigham, A.W.2
O'Connor, T.D.3
Fu, W.4
Kenny, E.E.5
Gravel, S.6
McGee, S.7
Do, R.8
Liu, X.9
Jun, G.10
Kang, H.M.11
Jordan, D.12
Leal, S.M.13
Gabriel, S.14
Rieder, M.J.15
Abecasis, G.16
Altshuler, D.17
Nickerson, D.A.18
Boerwinkle, E.19
Sunyaev, S.20
Bustamante, C.D.21
Bamshad, M.J.22
Akey, J.M.23
more..
-
3
-
-
84931286363
-
-
A Deep Catalog of Human Genetic Variation. http://www.1000genomes.org.
-
-
-
-
4
-
-
84931286364
-
-
Personal Genome Project. http://www.personalgenomes.org.
-
-
-
-
5
-
-
84931286365
-
Bridging the informatics gap between bench and bedside: implications to neurodegenerative diseases
-
Edited by Mandel S. Berlin: Springer
-
Shabo A, Scarpa M: Bridging the informatics gap between bench and bedside: implications to neurodegenerative diseases. In Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future. Edited by Mandel S. Berlin: Springer; 2013:301-308.
-
(2013)
In Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future
, pp. 301-308
-
-
Shabo, A.1
Scarpa, M.2
-
6
-
-
84931286366
-
-
Clinical Data Interchange Standards Consortium. http://www.cdisc.org/.
-
-
-
-
7
-
-
84870710995
-
General report & recommendations in predictive, preventive and personalised medicine 2012: white paper of the European association of predictive, preventive and personalised medicine
-
Golubnitschaja O, Costigliola V, EPMA: General report & recommendations in predictive, preventive and personalised medicine 2012: white paper of the European association of predictive, preventive and personalised medicine. EPMA J 2012, 3:14.
-
(2012)
EPMA J
, vol.3
, pp. 14
-
-
Golubnitschaja, O.1
Costigliola, V.2
-
8
-
-
40749105508
-
Variations in DNA elucidate molecular networks that cause disease
-
Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE: Variations in DNA elucidate molecular networks that cause disease. Nature 2008, 452:429-435.
-
(2008)
Nature
, vol.452
, pp. 429-435
-
-
Chen, Y.1
Zhu, J.2
Lum, P.Y.3
Yang, X.4
Pinto, S.5
MacNeil, D.J.6
Zhang, C.7
Lamb, J.8
Edwards, S.9
Sieberts, S.K.10
Leonardson, A.11
Castellini, L.W.12
Wang, S.13
Champy, M.F.14
Zhang, B.15
Emilsson, V.16
Doss, S.17
Ghazalpour, A.18
Horvath, S.19
Drake, T.A.20
Lusis, A.J.21
Schadt, E.E.22
more..
-
9
-
-
41349095280
-
Genetics of gene expression and its effect on disease
-
Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, Zhu J, Carlson S, Helgason A, Walters GB, Gunnarsdottir S, Mouy M, Steinthorsdottir V, Eiriksdottir GH, Bjornsdottir G, Reynisdottir I, Gudbjartsson D, Helgadottir A, Jonasdottir A, Jonasdottir A, Styrkarsdottir U, Gretarsdottir S, Magnusson KP, Stefansson H, Fossdal R, Kristjansson K, Gislason HG, Stefansson T, Leifsson BG, Thorsteinsdottir U, Lamb JR, et al: Genetics of gene expression and its effect on disease. Nature 2008, 452:423-428.
-
(2008)
Nature
, vol.452
, pp. 423-428
-
-
Emilsson, V.1
Thorleifsson, G.2
Zhang, B.3
Leonardson, A.S.4
Zink, F.5
Zhu, J.6
Carlson, S.7
Helgason, A.8
Walters, G.B.9
Gunnarsdottir, S.10
Mouy, M.11
Steinthorsdottir, V.12
Eiriksdottir, G.H.13
Bjornsdottir, G.14
Reynisdottir, I.15
Gudbjartsson, D.16
Helgadottir, A.17
Jonasdottir, A.18
Jonasdottir, A.19
Styrkarsdottir, U.20
Gretarsdottir, S.21
Magnusson, K.P.22
Stefansson, H.23
Fossdal, R.24
Kristjansson, K.25
Gislason, H.G.26
Stefansson, T.27
Leifsson, B.G.28
Thorsteinsdottir, U.29
Lamb, J.R.30
more..
-
10
-
-
77952720637
-
Genome-wide association studies and beyond
-
Witte JS: Genome-wide association studies and beyond. Annu Rev Publ Health 2010, 31:9-20.
-
(2010)
Annu Rev Publ Health
, vol.31
, pp. 9-20
-
-
Witte, J.S.1
-
11
-
-
67649259165
-
Computational disease modeling-fact or fiction?
-
Tegner J, Compte A, Auffray C, An G, Cedersund G, Clermont G, Gutkin B, Oltvai Z, Stephan K, Thomas R, Villoslada P: Computational disease modeling-fact or fiction? BMC Syst Biol 2009, 3:56.
-
(2009)
BMC Syst Biol
, vol.3
, pp. 56
-
-
Tegner, J.1
Compte, A.2
Auffray, C.3
An, G.4
Cedersund, G.5
Clermont, G.6
Gutkin, B.7
Oltvai, Z.8
Stephan, K.9
Thomas, R.10
Villoslada, P.11
-
12
-
-
84931266631
-
Integrating pathways of Parkinson's disease in a molecular interaction map
-
Fujita KA, Ostaszewski M, Matsuoka Y, Ghosh S, Glaab E, Trefois C, Crespo I, Perumal TM, Jurkowski W, Antony PM, Diederich N, Buttini M, Kodama A, Satagopam VP, Eifes S, Del Sol A, Schneider R, Kitano H, Balling R: Integrating pathways of Parkinson's disease in a molecular interaction map. Mol Neurobiol 2013:1-15.
-
(2013)
Mol Neurobiol
, pp. 1-15
-
-
Fujita, K.A.1
Ostaszewski, M.2
Matsuoka, Y.3
Ghosh, S.4
Glaab, E.5
Trefois, C.6
Crespo, I.7
Perumal, T.M.8
Jurkowski, W.9
Antony, P.M.10
Diederich, N.11
Buttini, M.12
Kodama, A.13
Satagopam, V.P.14
Eifes, S.15
Del Sol, A.16
Schneider, R.17
Kitano, H.18
Balling, R.19
-
13
-
-
33845450589
-
Mining literature for systems biology
-
Roberts PM: Mining literature for systems biology. Brief Bioinform 2006, 7:399-406.
-
(2006)
Brief Bioinform
, vol.7
, pp. 399-406
-
-
Roberts, P.M.1
-
14
-
-
84861643512
-
Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks
-
Martin F, Thomson TM, Sewer A, Drubin DA, Mathis C, Weisensee D, Pratt D, Hoeng J, Peitsch MC: Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks. BMC Syst Biol 2012, 6:54.
-
(2012)
BMC Syst Biol
, vol.6
, pp. 54
-
-
Martin, F.1
Thomson, T.M.2
Sewer, A.3
Drubin, D.A.4
Mathis, C.5
Weisensee, D.6
Pratt, D.7
Hoeng, J.8
Peitsch, M.C.9
-
15
-
-
33750351769
-
Data-driven modeling of signal-transduction networks
-
Janes KA, Yaffe MB: Data-driven modeling of signal-transduction networks. Nat Rev Mol Cell Biol 2006, 7:820-828.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 820-828
-
-
Janes, K.A.1
Yaffe, M.B.2
-
16
-
-
79960897495
-
A novel knowledge-driven systems biology approach for phenotype prediction upon genetic intervention
-
Chang R, Shoemaker R, Wang W: A novel knowledge-driven systems biology approach for phenotype prediction upon genetic intervention. IEEE/ACM Trans Comp Biol Bioinform 2010, 8:1170-1182.
-
(2010)
IEEE/ACM Trans Comp Biol Bioinform
, vol.8
, pp. 1170-1182
-
-
Chang, R.1
Shoemaker, R.2
Wang, W.3
-
17
-
-
33751111173
-
Text mining and its potential applications in systems biology
-
Ananiadou S, Kell DB, Tsujii JI: Text mining and its potential applications in systems biology. Trends Biotechnol 2006, 24:571-579.
-
(2006)
Trends Biotechnol
, vol.24
, pp. 571-579
-
-
Ananiadou, S.1
Kell, D.B.2
Tsujii, J.I.3
-
18
-
-
84931286367
-
-
The Biological Expression Language. http://www.openbel.org.
-
-
-
-
19
-
-
23244465303
-
Biomarkers: potential uses and limitations
-
Mayeux R: Biomarkers: potential uses and limitations. NeuroRx 2004, 1:182-188.
-
(2004)
NeuroRx
, vol.1
, pp. 182-188
-
-
Mayeux, R.1
-
20
-
-
77954127988
-
Systems biology and the discovery of diagnostic biomarkers
-
Wang K, Lee I, Carlson G, Hood L, Galas D: Systems biology and the discovery of diagnostic biomarkers. Dis Markers 2010, 28:199-207.
-
(2010)
Dis Markers
, vol.28
, pp. 199-207
-
-
Wang, K.1
Lee, I.2
Carlson, G.3
Hood, L.4
Galas, D.5
-
21
-
-
61949139765
-
Identification of discriminating biomarkers for human disease using integrative network biology
-
Dudley JT, Butte AJ: Identification of discriminating biomarkers for human disease using integrative network biology. Pac Symp Biocomput 2009:27-38.
-
(2009)
Pac Symp Biocomput
, pp. 27-38
-
-
Dudley, J.T.1
Butte, A.J.2
-
22
-
-
35348891430
-
Network-based classification of breast cancer metastasis
-
Chuang HY, Lee E, Liu YT, Lee D, Ideker T: Network-based classification of breast cancer metastasis. Mol Syst Biol 2007, 3:140.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 140
-
-
Chuang, H.Y.1
Lee, E.2
Liu, Y.T.3
Lee, D.4
Ideker, T.5
-
23
-
-
84931286368
-
Bridging clinical knowledge to molecular events through integration of imaging biomarkers and protein interactions in Alzheimer's disease
-
Younesi E, Hofmann-Apitius M: Bridging clinical knowledge to molecular events through integration of imaging biomarkers and protein interactions in Alzheimer's disease. http://www.iscb.org/archive/conferences/iscb/cms_addon/ conferences/ismbeccb2011/posterlist8ba3.html?cat=X.
-
-
-
Younesi, E.1
Hofmann-Apitius, M.2
-
24
-
-
80053235012
-
Computationally generated cardiac biomarkers for risk stratification after acute coronary syndrome
-
Syed Z, Stultz CM, Scirica BM, Guttag JV: Computationally generated cardiac biomarkers for risk stratification after acute coronary syndrome. Sci Transl Med 2011, 3:102ra95.
-
(2011)
Sci Transl Med
, vol.3
-
-
Syed, Z.1
Stultz, C.M.2
Scirica, B.M.3
Guttag, J.V.4
-
25
-
-
77957898888
-
How does diabetes accelerate Alzheimer disease pathology?
-
Sims-Robinson C, Kim B, Rosko A, Feldman EL: How does diabetes accelerate Alzheimer disease pathology? Nat Rev Neurol 2010, 6:551-559.
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 551-559
-
-
Sims-Robinson, C.1
Kim, B.2
Rosko, A.3
Feldman, E.L.4
-
26
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
Ott A, Stolk RP, van Harskamp F, Grobbee DE, Breteler MM: Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 1999, 53:1937-1942.
-
(1999)
Neurology
, vol.53
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
van Harskamp, F.3
Grobbee, D.E.4
Breteler, M.M.5
-
27
-
-
68949089312
-
Alzheimer's disease is type 3 diabetesevidence reviewed
-
de la Monte SM, Wands JR: Alzheimer's disease is type 3 diabetesevidence reviewed. J Diabetes Sci Technol 2008, 2:1101-1113.
-
(2008)
J Diabetes Sci Technol
, vol.2
, pp. 1101-1113
-
-
de la Monte, S.M.1
Wands, J.R.2
-
28
-
-
79251623365
-
Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?
-
Akter K, Lanza EA, Martin SA, Myronyuk N, Rua M, Raffa RB: Diabetes mellitus and Alzheimer's disease: shared pathology and treatment? Brit J Clin Pharmaco 2011, 71:365-376.
-
(2011)
Brit J Clin Pharmaco
, vol.71
, pp. 365-376
-
-
Akter, K.1
Lanza, E.A.2
Martin, S.A.3
Myronyuk, N.4
Rua, M.5
Raffa, R.B.6
-
29
-
-
84866062805
-
Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia
-
Yaffe K, Falvey C, Hamilton N, Schwartz AV, Simonsick EM, Satterfield S, Cauley JA, Rosano C, Launer LJ, Strotmeyer ES, Harris TB: Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia. Arch Neurol 2012, 9:1170-1175.
-
(2012)
Arch Neurol
, vol.9
, pp. 1170-1175
-
-
Yaffe, K.1
Falvey, C.2
Hamilton, N.3
Schwartz, A.V.4
Simonsick, E.M.5
Satterfield, S.6
Cauley, J.A.7
Rosano, C.8
Launer, L.J.9
Strotmeyer, E.S.10
Harris, T.B.11
-
30
-
-
84859726053
-
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease-associated Aß oligomers
-
Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel J-C, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG: An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease-associated Aß oligomers. J Clin Invest 2012, 122:1339-1353.
-
(2012)
J Clin Invest
, vol.122
, pp. 1339-1353
-
-
Bomfim, T.R.1
Forny-Germano, L.2
Sathler, L.B.3
Brito-Moreira, J.4
Houzel, J.-C.5
Decker, H.6
Silverman, M.A.7
Kazi, H.8
Melo, H.M.9
McClean, P.L.10
Holscher, C.11
Arnold, S.E.12
Talbot, K.13
Klein, W.L.14
Munoz, D.P.15
Ferreira, S.T.16
De Felice, F.G.17
-
31
-
-
79955749452
-
The diabetes drug Liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
-
McClean P, Parthsarathy V, Faivre E, Hölscher C: The diabetes drug Liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease. J Neurosci 2011, 31:6587-6594.
-
(2011)
J Neurosci
, vol.31
, pp. 6587-6594
-
-
McClean, P.1
Parthsarathy, V.2
Faivre, E.3
Hölscher, C.4
-
32
-
-
84856492410
-
The effect of rosiglitazone on LRP1 expression and amyloid ß uptake in human brain microvascular endothelial cells: a possible role of a low-dose thiazolidinedione for dementia treatment
-
Moona JH, Kima HJ, Yanga AH, Kima HM, Leea BW, Kanga ES, Leea HC, Cha BS: The effect of rosiglitazone on LRP1 expression and amyloid ß uptake in human brain microvascular endothelial cells: a possible role of a low-dose thiazolidinedione for dementia treatment. Int J Neuropsychopharmacol 2012, 15:135-142.
-
(2012)
Int J Neuropsychopharmacol
, vol.15
, pp. 135-142
-
-
Moona, J.H.1
Kima, H.J.2
Yanga, A.H.3
Kima, H.M.4
Leea, B.W.5
Kanga, E.S.6
Leea, H.C.7
Cha, B.S.8
-
33
-
-
84880946972
-
A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effect
-
Younesi E, Hofmann-Apitius M: A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effect. J Transl Med 2013, 11:177.
-
(2013)
J Transl Med
, vol.11
, pp. 177
-
-
Younesi, E.1
Hofmann-Apitius, M.2
-
34
-
-
84858386698
-
Personalized medicine is more than genomic medicine: confusion over terminology impedes progress towards personalized healthcare
-
Simmons LA, Dinan MA, Robinson TJ, Snyderman R: Personalized medicine is more than genomic medicine: confusion over terminology impedes progress towards personalized healthcare. Pers Med 2012, 9:85-91.
-
(2012)
Pers Med
, vol.9
, pp. 85-91
-
-
Simmons, L.A.1
Dinan, M.A.2
Robinson, T.J.3
Snyderman, R.4
-
35
-
-
77955558435
-
The promises of personalized medicine
-
Cascorbi I: The promises of personalized medicine. Eur J Clin Pharmacol 2010, 66:749-754.
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 749-754
-
-
Cascorbi, I.1
-
36
-
-
75149194970
-
Progress towards personalized medicine
-
Bates S: Progress towards personalized medicine. Drug Discov Today 2010, 15:115.
-
(2010)
Drug Discov Today
, vol.15
, pp. 115
-
-
Bates, S.1
-
37
-
-
80054004797
-
The biomarker is not the end
-
Nohaile M: The biomarker is not the end. Drug Discov Today 2011, 16:878-883.
-
(2011)
Drug Discov Today
, vol.16
, pp. 878-883
-
-
Nohaile, M.1
-
38
-
-
84879910284
-
Challenges and opportunities for oncology biomarker discovery
-
Deyati A, Younesi E, Hofmann-Apitius M, Novac N: Challenges and opportunities for oncology biomarker discovery. Drug Discov Today 2012, 18:614-624.
-
(2012)
Drug Discov Today
, vol.18
, pp. 614-624
-
-
Deyati, A.1
Younesi, E.2
Hofmann-Apitius, M.3
Novac, N.4
-
39
-
-
84859720700
-
Genes associated with intestinal permeability in ulcerative colitis: Changes in expression following infliximab therapy
-
Toedter G, Li K, Sague S, Ma K, Marano C, Macoritto M, Park J, Deehan R, Matthews A, Wu GD, Lewis JD, Arijs I, Rutgeerts P, Baribaud F: Genes associated with intestinal permeability in ulcerative colitis: Changes in expression following infliximab therapy. Inflamm Bowel Dis 2012, 18:1399-1410.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 1399-1410
-
-
Toedter, G.1
Li, K.2
Sague, S.3
Ma, K.4
Marano, C.5
Macoritto, M.6
Park, J.7
Deehan, R.8
Matthews, A.9
Wu, G.D.10
Lewis, J.D.11
Arijs, I.12
Rutgeerts, P.13
Baribaud, F.14
-
40
-
-
84871961943
-
Patient-centered medicine and patient-oriented research: improving health outcomes for individual patients
-
Sacristán JA: Patient-centered medicine and patient-oriented research: improving health outcomes for individual patients. BMC Med Inf Decis Making 2013, 13:6.
-
(2013)
BMC Med Inf Decis Making
, vol.13
, pp. 6
-
-
Sacristán, J.A.1
-
41
-
-
84931286369
-
-
PatientsLikeMe website. www.patientslikeme.com.
-
-
-
-
42
-
-
79955778144
-
Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm
-
Wicks P, Vaughan TE, Massagli MP, Heywood J: Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm. Nat Biotechnol 2011, 29:411-414.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 411-414
-
-
Wicks, P.1
Vaughan, T.E.2
Massagli, M.P.3
Heywood, J.4
-
43
-
-
80052329143
-
Using electronic patient records to discover disease correlations and stratify patient cohorts
-
Roque FS, Jensen PB, Schmock H, Dalgaard M, Andreatta M, Hansen T, Søeby K, Bredkjær S, Juul A, Werge T, Jensen LJ, Brunak S: Using electronic patient records to discover disease correlations and stratify patient cohorts. PLoS Comput Biol 2011, 7:e1002141.
-
(2011)
PLoS Comput Biol
, vol.7
-
-
Roque, F.S.1
Jensen, P.B.2
Schmock, H.3
Dalgaard, M.4
Andreatta, M.5
Hansen, T.6
Søeby, K.7
Bredkjær, S.8
Juul, A.9
Werge, T.10
Jensen, L.J.11
Brunak, S.12
-
44
-
-
84897564754
-
ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease
-
Malhotra A, Younesi E, Gündel M, Müller B, Heneka MT, Hofmann-Apitius M: ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease. Alzheimers Dement 2013, doi: 10.1016/j.jalz.2013.02.009.
-
(2013)
Alzheimers Dement
-
-
Malhotra, A.1
Younesi, E.2
Gündel, M.3
Müller, B.4
Heneka, M.T.5
Hofmann-Apitius, M.6
-
45
-
-
84931286370
-
-
Self-tracking project. www.quantifiedself.com.
-
-
-
-
46
-
-
0040368216
-
Prospects for new restorative and neuroprotective treatments in Parkinson's disease
-
Dunnett SB, Björklund A: Prospects for new restorative and neuroprotective treatments in Parkinson's disease. Nature 1999, 399:A32-A39.
-
(1999)
Nature
, vol.399
, pp. A32-A39
-
-
Dunnett, S.B.1
Björklund, A.2
-
47
-
-
34447521460
-
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology
-
Loscalzo J, Kohane I, Barabasi AL: Human disease classification in the postgenomic era: a complex systems approach to human pathobiology. Mol Syst Biol 2007, 3:124.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 124
-
-
Loscalzo, J.1
Kohane, I.2
Barabasi, A.L.3
-
49
-
-
84858978535
-
Drug repositioning for personalized medicine
-
Li YY, Jones SJM: Drug repositioning for personalized medicine. Genome Med 2012, 4:27.
-
(2012)
Genome Med
, vol.4
, pp. 27
-
-
Li, Y.Y.1
Jones, S.J.M.2
-
51
-
-
79960797592
-
Computational methods for drug repurposing
-
Sanseau P, Koehler J: Computational methods for drug repurposing. Briefings Bioinf 2011, 12:301-302.
-
(2011)
Briefings Bioinf
, vol.12
, pp. 301-302
-
-
Sanseau, P.1
Koehler, J.2
-
52
-
-
84875340644
-
SVM based descriptor selection and classification of neurodegenerative disease drugs for pharmacological modeling
-
Shahid M, Shahzad Cheema M, Klenner A, Younesi E, Hofmann-Apitius M: SVM based descriptor selection and classification of neurodegenerative disease drugs for pharmacological modeling. Mol Inf 2013, 32:241-249.
-
(2013)
Mol Inf
, vol.32
, pp. 241-249
-
-
Shahid, M.1
Shahzad Cheema, M.2
Klenner, A.3
Younesi, E.4
Hofmann-Apitius, M.5
-
54
-
-
0035885179
-
Effective decision-making: progressing compounds through clinical development
-
Shillingford CA, Vose CW: Effective decision-making: progressing compounds through clinical development. Drug Discov Today 2001, 6:941-946.
-
(2001)
Drug Discov Today
, vol.6
, pp. 941-946
-
-
Shillingford, C.A.1
Vose, C.W.2
-
55
-
-
77950679333
-
Can animal models of disease reliably inform human studies?
-
van der Worp HB, Howells DW, Sena ES, Porritt MJ, Rewell S, O'Collins V, Macleod MR: Can animal models of disease reliably inform human studies? PLoS Med 2010, 7:e1000245.
-
(2010)
PLoS Med
, vol.7
-
-
van der Worp, H.B.1
Howells, D.W.2
Sena, E.S.3
Porritt, M.J.4
Rewell, S.5
O'Collins, V.6
Macleod, M.R.7
-
56
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, et al: Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A 2013, 110:3507-3512.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 3507-3512
-
-
Seok, J.1
Warren, H.S.2
Cuenca, A.G.3
Mindrinos, M.N.4
Baker, H.V.5
Xu, W.6
Richards, D.R.7
McDonald-Smith, G.P.8
Gao, H.9
Hennessy, L.10
Finnerty, C.C.11
López, C.M.12
Honari, S.13
Moore, E.E.14
Minei, J.P.15
Cuschieri, J.16
Bankey, P.E.17
Johnson, J.L.18
Sperry, J.19
Nathens, A.B.20
Billiar, T.R.21
West, M.A.22
Jeschke, M.G.23
Klein, M.B.24
Gamelli, R.L.25
Gibran, N.S.26
Brownstein, B.H.27
Miller-Graziano, C.28
Calvano, S.E.29
Mason, P.H.30
more..
-
58
-
-
78149320656
-
The benefits and limitations of animal models for translational research in neurodegenerative diseases
-
Jucker M: The benefits and limitations of animal models for translational research in neurodegenerative diseases. Nat Med 2010, 16:1210-1214.
-
(2010)
Nat Med
, vol.16
, pp. 1210-1214
-
-
Jucker, M.1
-
59
-
-
84931286372
-
-
IMPROVER Systems Biology Verification Challenge. https://www.sbvimprover.com/.
-
-
-
-
60
-
-
84870710995
-
EPMA: General report & recommendations in predictive, preventive and personalised medicine 2012: white paper of the European association of predictive, preventive and personalised medicine
-
Golubnitschaja O, Costigliola V: EPMA: General report & recommendations in predictive, preventive and personalised medicine 2012: white paper of the European association of predictive, preventive and personalised medicine. EPMA J 2012, 3:14.
-
(2012)
EPMA J
, vol.3
, pp. 14
-
-
Golubnitschaja, O.1
Costigliola, V.2
|