-
1
-
-
76949088232
-
A review of human carcinogens-Part E: Tobacco, areca nut, alcohol, coal smoke, and salted fish
-
Secretan B, Straif K, Baan R, et al. A review of human carcinogens-Part E: Tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol 2009; 10:1033-1034.
-
(2009)
Lancet Oncol
, vol.10
, pp. 1033-1034
-
-
Secretan, B.1
Straif, K.2
Baan, R.3
-
2
-
-
84860389173
-
Global oral health inequalities in incidence and outcomes for oral cancer: Causes and solutions
-
Johnson NW, Warnakulasuriya S, Gupta PC, et al. Global oral health inequalities in incidence and outcomes for oral cancer: Causes and solutions. Adv Dent Res 2011; 23:237-246.
-
(2011)
Adv Dent Res
, vol.23
, pp. 237-246
-
-
Johnson, N.W.1
Warnakulasuriya, S.2
Gupta, P.C.3
-
3
-
-
84855755447
-
A review of the epidemiology of oral and pharyngeal carcinoma: Update
-
Saman DM. A review of the epidemiology of oral and pharyngeal carcinoma: Update. Head neck oncol 2012; 4:1.
-
(2012)
Head neck oncol
, vol.4
, pp. 1
-
-
Saman, D.M.1
-
4
-
-
49749121765
-
Head and neck cancer in the betel quid chewing area: Recent advances in molecular carcinogenesis
-
Chen YJ, Chang JT, Liao CT, et al. Head and neck cancer in the betel quid chewing area: Recent advances in molecular carcinogenesis. Cancer Sci 2008; 99:1507-1514.
-
(2008)
Cancer Sci
, vol.99
, pp. 1507-1514
-
-
Chen, Y.J.1
Chang, J.T.2
Liao, C.T.3
-
5
-
-
77952537235
-
Oral cavity risk factors: Experts' opinions and literature support
-
Stucken E, Weissman J, Spiegel JH. Oral cavity risk factors: Experts' opinions and literature support. Head Neck Surg 2010; 39:76-89.
-
(2010)
Head Neck Surg
, vol.39
, pp. 76-89
-
-
Stucken, E.1
Weissman, J.2
Spiegel, J.H.3
-
7
-
-
13744254796
-
IARC Betel-quid and areca-nut chewing and some areca-nut derived nitrosamines
-
IARC Betel-quid and areca-nut chewing and some areca-nut derived nitrosamines. IARC Monog Eval Carc 2004; 85:1-334.
-
(2004)
IARC Monog Eval Carc
, vol.85
, pp. 1-334
-
-
-
8
-
-
0033081354
-
Effects of areca nut, inflorescence piper betle extracts and arecoline on cytotoxicity, total and unscheduled DNA synthesis in cultured gingival keratinocytes
-
Jeng JH, Hahn LJ, Lin BR, Hsieh CC, Chan CP, Chang MC. Effects of areca nut, inflorescence piper betle extracts and arecoline on cytotoxicity, total and unscheduled DNA synthesis in cultured gingival keratinocytes. J Oral Pathol Med 1999; 28:64-71.
-
(1999)
J Oral Pathol Med
, vol.28
, pp. 64-71
-
-
Jeng, J.H.1
Hahn, L.J.2
Lin, B.R.3
Hsieh, C.C.4
Chan, C.P.5
Chang, M.C.6
-
9
-
-
46449087780
-
Arecoline, a major alkaloid of areca nut, inhibits p53, represses DNA repair, and triggers DNA damage response in human epithelial cells
-
Tsai YS, Lee KW, Huang JL, et al. Arecoline, a major alkaloid of areca nut, inhibits p53, represses DNA repair, and triggers DNA damage response in human epithelial cells. Toxicology 2008; 249:230-237.
-
(2008)
Toxicology
, vol.249
, pp. 230-237
-
-
Tsai, Y.S.1
Lee, K.W.2
Huang, J.L.3
-
10
-
-
69249088563
-
Regulation of oxidative-stress responsive genes by arecoline in human keratinocytes
-
Thangjam GS, Kondaiah P. Regulation of oxidative-stress responsive genes by arecoline in human keratinocytes. J Periodontal Res 2009; 44:673-682.
-
(2009)
J Periodontal Res
, vol.44
, pp. 673-682
-
-
Thangjam, G.S.1
Kondaiah, P.2
-
11
-
-
10944233923
-
The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation
-
Chang MC, Wu HL, Lee JJ, et al. The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation. J Biol Chem 2004; 279:50676-50683.
-
(2004)
J Biol Chem
, vol.279
, pp. 50676-50683
-
-
Chang, M.C.1
Wu, H.L.2
Lee, J.J.3
-
12
-
-
60849098469
-
Areca nut extracts increased expression of inflammatory cytokines, tumor necrosis factor-alpha, interleukin-1beta, interleukin-6 and interleukin-8, in peripheral blood mononuclear cells
-
Chang LY, Wan HC, Lai YL, et al. Areca nut extracts increased expression of inflammatory cytokines, tumor necrosis factor-alpha, interleukin-1beta, interleukin-6 and interleukin-8, in peripheral blood mononuclear cells. J Periodontal Res 2009; 44:175-183.
-
(2009)
J Periodontal Res
, vol.44
, pp. 175-183
-
-
Chang, L.Y.1
Wan, H.C.2
Lai, Y.L.3
-
13
-
-
84888048833
-
Areca nut extracts increased the expression of cyclooxygenase-2, prostaglandin E2 and interleukin-1alpha in human immune cells via oxidative stress
-
Chang LY, Wan HC, Lai YL, Chou IC, Chen YT, Hung SL. Areca nut extracts increased the expression of cyclooxygenase-2, prostaglandin E2 and interleukin-1alpha in human immune cells via oxidative stress. Arch Oral Biol 2013; 58:1523-1531.
-
(2013)
Arch Oral Biol
, vol.58
, pp. 1523-1531
-
-
Chang, L.Y.1
Wan, H.C.2
Lai, Y.L.3
Chou, I.C.4
Chen, Y.T.5
Hung, S.L.6
-
14
-
-
33745714764
-
Ingredients contribute to variation in production of reactive oxygen species by areca quid
-
Chen PH, Tsai CC, Lin YC, et al. Ingredients contribute to variation in production of reactive oxygen species by areca quid. J Toxicol Environ Health A 2006; 69:1055-1069.
-
(2006)
J Toxicol Environ Health A
, vol.69
, pp. 1055-1069
-
-
Chen, P.H.1
Tsai, C.C.2
Lin, Y.C.3
-
15
-
-
77957751263
-
Arecoline, a major alkaloid of the areca nut, causes neurotoxicity through enhancement of oxidative stress and suppression of the antioxidant protective system
-
Shih YT, Chen PS, Wu CH, Tseng YT, Wu YC, Lo YC. Arecoline, a major alkaloid of the areca nut, causes neurotoxicity through enhancement of oxidative stress and suppression of the antioxidant protective system. Free Radic Biol Med 2010; 49:1471-1479.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 1471-1479
-
-
Shih, Y.T.1
Chen, P.S.2
Wu, C.H.3
Tseng, Y.T.4
Wu, Y.C.5
Lo, Y.C.6
-
16
-
-
79956216634
-
Arecoline-mediated inhibition of AMP-activated protein kinase through reactive oxygen species is required for apoptosis induction
-
Yen CY, Lin MH, Liu SY, et al. Arecoline-mediated inhibition of AMP-activated protein kinase through reactive oxygen species is required for apoptosis induction. Oral Oncol 2011; 47:345-351.
-
(2011)
Oral Oncol
, vol.47
, pp. 345-351
-
-
Yen, C.Y.1
Lin, M.H.2
Liu, S.Y.3
-
17
-
-
78751499344
-
Downregulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract
-
Chen YJ, Liao CT, Chen PJ, et al. Downregulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract. Head Neck 2011; 33:257-266.
-
(2011)
Head Neck
, vol.33
, pp. 257-266
-
-
Chen, Y.J.1
Liao, C.T.2
Chen, P.J.3
-
18
-
-
69549129415
-
Transcriptome profiling and network pathway analysis of genes associated with invasive phenotype in oral cancer
-
Kang CJ, Chen YJ, Liao CT, et al. Transcriptome profiling and network pathway analysis of genes associated with invasive phenotype in oral cancer. Cancer Lett 2009; 284:131-140.
-
(2009)
Cancer Lett
, vol.284
, pp. 131-140
-
-
Kang, C.J.1
Chen, Y.J.2
Liao, C.T.3
-
19
-
-
84864853674
-
Oncogenic function and early detection potential of miRNA-10b in oral cancer as identified by microRNA profiling
-
Lu YC, Chen YJ, Wang HM, et al. Oncogenic function and early detection potential of miRNA-10b in oral cancer as identified by microRNA profiling. Cancer Prev Res 2012; 5:665-674.
-
(2012)
Cancer Prev Res
, vol.5
, pp. 665-674
-
-
Lu, Y.C.1
Chen, Y.J.2
Wang, H.M.3
-
20
-
-
79960431337
-
Molecular chaperones as a common set of proteins that regulate the invasion phenotype of head and neck cancer
-
Chiu CC, Lin CY, Lee LY, et al. Molecular chaperones as a common set of proteins that regulate the invasion phenotype of head and neck cancer. Clin Cancer Res 2011; 17:4629-4641.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4629-4641
-
-
Chiu, C.C.1
Lin, C.Y.2
Lee, L.Y.3
-
21
-
-
84886972640
-
Grp78 as a therapeutic target for refractory head-neck cancer with CD24(-)CD44(+) stemness phenotype
-
Chiu CC, Lee LY, Li YC, et al. Grp78 as a therapeutic target for refractory head-neck cancer with CD24(-)CD44(+) stemness phenotype. Cancer Gene Ther 2013; 20:606-615.
-
(2013)
Cancer Gene Ther
, vol.20
, pp. 606-615
-
-
Chiu, C.C.1
Lee, L.Y.2
Li, Y.C.3
-
22
-
-
77955923224
-
Proteomics of the radioresistant phenotype in head-and-neck cancer: Gp96 as a novel prediction marker and sensitizing target for radiotherapy
-
Lin TY, Chang JT, Wang HM, et al. Proteomics of the radioresistant phenotype in head-and-neck cancer: Gp96 as a novel prediction marker and sensitizing target for radiotherapy. Int J Radiat Oncol Bio Phys 2010; 78:246-256.
-
(2010)
Int J Radiat Oncol Bio Phys
, vol.78
, pp. 246-256
-
-
Lin, T.Y.1
Chang, J.T.2
Wang, H.M.3
-
23
-
-
77955611544
-
Positive association of glucose-regulated protein 78 during oral cancer progression and the prognostic value in oral precancerous lesions
-
Lin CY, Chen WH, Liao CT, et al. Positive association of glucose-regulated protein 78 during oral cancer progression and the prognostic value in oral precancerous lesions. Head Neck 2010; 32:1028-1039.
-
(2010)
Head Neck
, vol.32
, pp. 1028-1039
-
-
Lin, C.Y.1
Chen, W.H.2
Liao, C.T.3
-
24
-
-
84878499360
-
DSG3 facilitates cancer cell growth and invasion through the DSG3-plakoglobin-TCF/LEF-Myc/cyclin D1/MMP signaling pathway
-
Chen YJ, Lee LY, Chao YK, et al. DSG3 facilitates cancer cell growth and invasion through the DSG3-plakoglobin-TCF/LEF-Myc/cyclin D1/MMP signaling pathway. PLoS ONE 2013; 8:6e64088.
-
(2013)
PLoS ONE
, vol.8
, pp. 6e64088
-
-
Chen, Y.J.1
Lee, L.Y.2
Chao, Y.K.3
-
25
-
-
0029958876
-
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
-
Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996; 183:1797-1806.
-
(1996)
J Exp Med
, vol.183
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
26
-
-
84866324123
-
Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links
-
Scheel C, Weinberg RA. Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links. Semin Cancer Biol 2012; 22:396-403.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 396-403
-
-
Scheel, C.1
Weinberg, R.A.2
-
28
-
-
77958025244
-
Structure and function of the human breast cancer resistance protein (BCRP/ABCG2)
-
Ni Z, Bikadi Z, Rosenberg MF, Mao Q. Structure and function of the human breast cancer resistance protein (BCRP/ABCG2). Curr Drug Metab 2010; 11:603-617.
-
(2010)
Curr Drug Metab
, vol.11
, pp. 603-617
-
-
Ni, Z.1
Bikadi, Z.2
Rosenberg, M.F.3
Mao, Q.4
-
29
-
-
66749191640
-
Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death
-
Cortes-Wanstreet MM, Giedzinski E, Limoli CL, Luderer U. Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death. Mutagenesis 2009; 24:211-224.
-
(2009)
Mutagenesis
, vol.24
, pp. 211-224
-
-
Cortes-Wanstreet, M.M.1
Giedzinski, E.2
Limoli, C.L.3
Luderer, U.4
-
30
-
-
84859045046
-
Head and neck cancer stem cells
-
Krishnamurthy S, Nor JE. Head and neck cancer stem cells. J Dent Res 2012; 91:334-340.
-
(2012)
J Dent Res
, vol.91
, pp. 334-340
-
-
Krishnamurthy, S.1
Nor, J.E.2
-
31
-
-
84876489727
-
Cancer stem cells: the challenges ahead
-
Medema JP. Cancer stem cells: the challenges ahead. Nat Cell Biol 2013; 15:338-344.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 338-344
-
-
Medema, J.P.1
-
32
-
-
84872919631
-
Complexity of cancer stem cells
-
Sugihara E, Saya H. Complexity of cancer stem cells. Int J Cancer 2013; 132:1249-1259.
-
(2013)
Int J Cancer
, vol.132
, pp. 1249-1259
-
-
Sugihara, E.1
Saya, H.2
-
33
-
-
39449090031
-
CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis
-
Hurt EM, Kawasaki BT, Klarmann GJ, Thomas SB, Farrar WL. CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis. Br J Cancer 2008; 98:756-765.
-
(2008)
Br J Cancer
, vol.98
, pp. 756-765
-
-
Hurt, E.M.1
Kawasaki, B.T.2
Klarmann, G.J.3
Thomas, S.B.4
Farrar, W.L.5
-
34
-
-
84857063740
-
CD44(+)/CD24(-/low) cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome
-
Idowu MO, Kmieciak M, Dumur C, et al. CD44(+)/CD24(-/low) cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome. Hum Pathol 2012; 43:364-373.
-
(2012)
Hum Pathol
, vol.43
, pp. 364-373
-
-
Idowu, M.O.1
Kmieciak, M.2
Dumur, C.3
-
35
-
-
84872877297
-
CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival
-
Meng E, Long B, Sullivan P, et al. CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival. Clin Exp Metastasis 2012; 29:939-948.
-
(2012)
Clin Exp Metastasis
, vol.29
, pp. 939-948
-
-
Meng, E.1
Long, B.2
Sullivan, P.3
-
36
-
-
84883133349
-
Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer
-
Sinha N, Mukhopadhyay S, Das DN, Panda PK, Bhutia SK. Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer. Oral Oncol 2013; 49:854-862.
-
(2013)
Oral Oncol
, vol.49
, pp. 854-862
-
-
Sinha, N.1
Mukhopadhyay, S.2
Das, D.N.3
Panda, P.K.4
Bhutia, S.K.5
-
37
-
-
84873423783
-
Cancer stem cells in head and neck cancer
-
Allegra E, Trapasso S. Cancer stem cells in head and neck cancer. Onco Targets Ther 2012; 5:375-383.
-
(2012)
Onco Targets Ther
, vol.5
, pp. 375-383
-
-
Allegra, E.1
Trapasso, S.2
-
38
-
-
80051635974
-
A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma
-
Peng CH, Liao CT, Peng SC, et al. A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma. PLoS ONE 2011; 6:e23452.
-
(2011)
PLoS ONE
, vol.6
, pp. e23452
-
-
Peng, C.H.1
Liao, C.T.2
Peng, S.C.3
-
39
-
-
79956340181
-
Cytotoxic effects produced by arecoline correlated to epigenetic regulation in human K-562 cells
-
Lin PC, Chang WH, Chen YH, Lee CC, Lin YH, Chang JG. Cytotoxic effects produced by arecoline correlated to epigenetic regulation in human K-562 cells. J Toxicol Env Heal A 2011; 74:737-745.
-
(2011)
J Toxicol Env Heal A
, vol.74
, pp. 737-745
-
-
Lin, P.C.1
Chang, W.H.2
Chen, Y.H.3
Lee, C.C.4
Lin, Y.H.5
Chang, J.G.6
-
40
-
-
84855780139
-
Arecoline decreases interleukin-6 production and induces apoptosis and cell cycle arrest in human basal cell carcinoma cells
-
Huang LW, Hsieh BS, Cheng HL, Hu YC, Chang WT, Chang KL. Arecoline decreases interleukin-6 production and induces apoptosis and cell cycle arrest in human basal cell carcinoma cells. Toxicol Appl Pharmacol 2012; 258:199-207.
-
(2012)
Toxicol Appl Pharmacol
, vol.258
, pp. 199-207
-
-
Huang, L.W.1
Hsieh, B.S.2
Cheng, H.L.3
Hu, Y.C.4
Chang, W.T.5
Chang, K.L.6
-
41
-
-
84864282117
-
Arecoline induced cell cycle arrest, apoptosis, and cytotoxicity to human endothelial cells
-
Tseng SK, Chang MC, Su CY, et al. Arecoline induced cell cycle arrest, apoptosis, and cytotoxicity to human endothelial cells. Clin Oral Investig 2012; 16:1267-1273.
-
(2012)
Clin Oral Investig
, vol.16
, pp. 1267-1273
-
-
Tseng, S.K.1
Chang, M.C.2
Su, C.Y.3
-
42
-
-
84897909666
-
Impairment of thymocyte function via induction of apoptosis by areca nut extract
-
Lee CC, Lin YC, Liu HE, Jan TR, Wang CC. Impairment of thymocyte function via induction of apoptosis by areca nut extract. J Immunotoxicol 2014; 11:190-196.
-
(2014)
J Immunotoxicol
, vol.11
, pp. 190-196
-
-
Lee, C.C.1
Lin, Y.C.2
Liu, H.E.3
Jan, T.R.4
Wang, C.C.5
-
43
-
-
33745600572
-
Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte
-
Lu SY, Chang KW, Liu CJ, et al. Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte. Carcinogenesis 2006; 27:1273-1284.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1273-1284
-
-
Lu, S.Y.1
Chang, K.W.2
Liu, C.J.3
-
44
-
-
84883055477
-
Toxicity of areca nut ingredients: activation of CHK1/CHK2, induction of cell cycle arrest, and regulation of MMP-9 and TIMPs production in SAS epithelial cells
-
Chang MC, Chan CP, Wang WT, et al. Toxicity of areca nut ingredients: activation of CHK1/CHK2, induction of cell cycle arrest, and regulation of MMP-9 and TIMPs production in SAS epithelial cells. Head Neck 2013; 35:1295-1302.
-
(2013)
Head Neck
, vol.35
, pp. 1295-1302
-
-
Chang, M.C.1
Chan, C.P.2
Wang, W.T.3
-
45
-
-
34948862754
-
Up-regulation of matrix metalloproteinase-8 by betel quid extract and arecoline and its role in 2D motility
-
Liu SY, Liu YC, Huang WT, Huang GC, Chen TC, Lin MH. Up-regulation of matrix metalloproteinase-8 by betel quid extract and arecoline and its role in 2D motility. Oral Oncol 2007; 43:1026-1033.
-
(2007)
Oral Oncol
, vol.43
, pp. 1026-1033
-
-
Liu, S.Y.1
Liu, Y.C.2
Huang, W.T.3
Huang, G.C.4
Chen, T.C.5
Lin, M.H.6
-
46
-
-
50849109195
-
Areca nut extract represses migration and differentiation while activating matrix metalloproteinase-9 of normal gingival epithelial cells
-
Tseng YH, Chang KW, Liu CJ, Lin CY, Yang SC, Lin SC. Areca nut extract represses migration and differentiation while activating matrix metalloproteinase-9 of normal gingival epithelial cells. J Periodontal Res 2008; 43:490-499.
-
(2008)
J Periodontal Res
, vol.43
, pp. 490-499
-
-
Tseng, Y.H.1
Chang, K.W.2
Liu, C.J.3
Lin, C.Y.4
Yang, S.C.5
Lin, S.C.6
-
47
-
-
58149170720
-
Areca nut extract-treated gingival fibroblasts modulate the invasiveness of polymorphonuclear leukocytes via the production of MMP-2
-
Lu HH, Chen LK, Cheng CY, Hung SL, Lin SC, Chang KW. Areca nut extract-treated gingival fibroblasts modulate the invasiveness of polymorphonuclear leukocytes via the production of MMP-2. J Oral Path Med 2009; 38:79-86.
-
(2009)
J Oral Path Med
, vol.38
, pp. 79-86
-
-
Lu, H.H.1
Chen, L.K.2
Cheng, C.Y.3
Hung, S.L.4
Lin, S.C.5
Chang, K.W.6
-
48
-
-
84892885525
-
Long-term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity
-
Yen CY, Chiang WF, Liu SY, et al. Long-term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity. J Oral Path Med 2014; 43:91-96.
-
(2014)
J Oral Path Med
, vol.43
, pp. 91-96
-
-
Yen, C.Y.1
Chiang, W.F.2
Liu, S.Y.3
-
49
-
-
84904738363
-
Clinical evidence of field cancerization in patients with oral cavity cancer in a betel quid chewing area
-
Liao CT, Wallace CG, Lee LY, et al. Clinical evidence of field cancerization in patients with oral cavity cancer in a betel quid chewing area. Oral Oncol 2014; 50:721-731.
-
(2014)
Oral Oncol
, vol.50
, pp. 721-731
-
-
Liao, C.T.1
Wallace, C.G.2
Lee, L.Y.3
|