Cytotoxic effects produced by arecoline correlated to epigenetic regulation in human K-562 cells

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 74, Issue 11, 2011, Pages 737-745

  Lin, Pei Chin ^a,b   Chang, Wen Hsin ^b   Chen, Yung Hsiu ^a,b   Lee, Chien Chih ^c   Lin, Yi Hsiung ^c   Chang, Jan Gowth ^a,b,c  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ARECOLINE; HISTONE ACETYLTRANSFERASE; HISTONE DEMETHYLASE; HISTONE METHYLTRANSFERASE;

ARTICLE; CATALYSIS; CYTOTOXICITY; DEMETHYLATION; EPIGENETICS; GENE CONTROL; GENE EXPRESSION; GENOTOXICITY; HISTONE METHYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ARECOLINE; CELL LINE, TUMOR; CYTOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIGENESIS, GENETIC; GENE EXPRESSION; GENE EXPRESSION REGULATION; HISTONE ACETYLTRANSFERASES; HISTONE DEMETHYLASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; PLANT EXTRACTS; RNA, MESSENGER;

ARECA CATECHU;

EID: 79956340181     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287394.2011.539123     Document Type: Article

References (29)

1. Böse, J., Gruber, A., Helming, L., Schiebe, S., Wegener, I., Hafner, M., Beales, M., Köntgen, F., and Lengeling, A. 2004. The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal. J. Biol. 3:15.
2. Chang, B., Chen, Y., Zhao, Y., and Bruick, R. K. 2007. JMJD6 is a histone arginine demethylase. Science 318:444-447. (Pubitemid 47614528)
3. Chang, Y. C., Cheng, M. H., Huang, M. F., Liao, P. H., Chou, L. S., and Chou, M. Y. 1998. Effects of betel nut alkaloids on human gingival fibroblasts in vitro. Chin. Dent. J. 17: 23-29.
4. Chiang, S. L., Jiang, S. S., Wang, Y. J., Chiang, H. C., Chen, P. H., Tu, H. P., Ho, K. Y., Tsai, Y. S., Chang, I. S., and Ko, Y. C. 2007. Characterization of arecoline-induced effects on cytotoxicity in normal human gingival fibroblasts by global gene expression profiling. Toxicol. Sci. 100:66-74.
5. Chou, W. W., Guh, J. Y., Tsai, J. F., Hwang, C. C., Chen, H. C., Huang, J. S., Yang, Y. L., Hung, W. C., and Chuang, L. Y. 2008. Arecoline-induced growth arrest and p21WAF1 expression are dependent on p53 in rat hepatocytes. Toxicology 243:1-10.
6. Deb, S., and Chatterjee, A. 1998. Influence of buthionine sulfoximine and reduced glutathione on arecoline-induced chromosomal damage and sister chromatid exchange in mouse bone marrow cells in vivo. Mutagenesis 13:243-248. (Pubitemid 28243157)
7. Dolinoy, D. C., Weidman, J. R. and Jirtle, R. L. 2007. Epigenetic gene regulation: Linking early developmental environment to adult disease. Reproductive Toxicology 23: 297-307. (Pubitemid 46602921)
8. Dolinoy, D. C., and Jirtle, R. L. 2008. Environmental epigenomics in human health and disease. Environ. Mol. Mutagen. 49:4-8. (Pubitemid 351293007)
9. Holliday, R. 1987. The inheritance of epigenetic defects. Science 238:163-170. (Pubitemid 17139717)
10. Jeng, J. H., Kuo, M. L., Hahn, L. J., and Kuo, M. Y. 1994. Genotoxic and non-genotoxic effects of betel quid ingredients on oral mucosal fibroblasts in vitro. J. Dent. Res. 73:1043-1049.
11. Ko, Y. C., Chiang, T. A., Chang, S. J., andHsieh, S. F. 1992. Prevalence of betel quid chewing habit in Taiwan and related sociodemographic factors. J. Oral Pathol. Med. 21:261-264.
12. Ko, Y. C., Huang, Y. L., Lee, C. H., Chen, M. J., Lin, L. M., and Tsai, C. C. 1995. Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan. J. Oral Pathol. Med. 24:450-453.
13. Krauss, V. 2008. Glimpses of evolution: Heterochromatic histone H3K9 methyltransferases left its marks behind. Genetica 133:93-106. (Pubitemid 351464226)
14. Kumpawat, K., Deb, S., Ray, S., and Chatterjee, A. 2003. Genotoxic effect of raw betel-nut extract in relation to endogenous glutathione levels and its mechanism of action in mammalian cells. Mutat. Res. 538:1-12. (Pubitemid 36776682)
15. Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., and Jenuwein, T. 2001. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116-120. (Pubitemid 32225847)
16. Neilsen, S., Schneider, R., Bauer, U., Bannister, A., Morrison, A., O'Carroll, D., Firestein, R., Cleary, M., Jenuwein, T., and Herrera, R. 2001. Rb targets histone H3 methylation and HP1 to promoters. Nature 412:561-565. (Pubitemid 32743837)
17. Panigrahi, G. B., and Rao, A. R. 1986. Study of the genotoxicity of the total aqueous extract of betel nut and its tannin. Carcinogenesis 7:37-39. (Pubitemid 16184817)
18. Peters, A., O'Carroll, D., Scherthan, H., Mechtler, K., Sauer, S., Schöfer, C., Weipoltshammer, K., Pagani, M., Lachner, M., Kohlmaier, A., Opravil, S., Doyle, M., Sibilia, M., and Jenuwein, T. 2001. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107:323-337. (Pubitemid 33049976)
19. Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B., Sun, Z., Schmid, M., Opravil, S., Mechtler, K., Ponting, C., and Allis, C. 2000. Regulation of chromatin structure by site-specific histone H3 methylatransferases. Nature 406:593-599. (Pubitemid 30641039)
20. Rice, J., Briggs, S., Ueberheide, B., Barber, C., Shabanowitz, J., Hunt, D., Shinkai, Y., and Allis, C. 2003. Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol. Cell 12:1951-1958.
21. Sundqvist, K., Liu, Y., Nair, J., Bartsch, H., Arvidson, K., and Grafstrom, R. C. 1989. Cytotoxic and genotoxic effects of areca nut-related compounds in cultured human buccal epithelial cells. Cancer Res. 49:5294-5298. (Pubitemid 19240463)
22. Tamaru, H., and Selker, E. 2001. A histone methyltransferase controls DNA methylation in Neurospora grassa. Nature 414:277-283. (Pubitemid 33097798)
23. Trivedy, C. R., Craig, G., and Warnakulasuriya, S. 2002. The oral health consequences of chewing areca nut. Addict. Biol. 7:115-125. (Pubitemid 34087915)
24. Tsai, J. F., Chuang, L. Y., Jeng, J. E., Ho, M. S., Hsieh, M. Y., Lin, Z. Y., andWang, L. Y. 2001. Betel quid chewing as a risk factor for hepatocellular carcinoma: A ase-control study. Br. J. Cancer 84:709-713. (Pubitemid 32239009)
25. Winstock, A. 2002. Areca nut-abuse liability, dependence and public health. Addict. Biol. 7:133-138. (Pubitemid 34087917)
26. Wysocka, J., Allis, C. D., and Coonrod, S. 2006a. Histone arginine methylation and its dynamic regulation. Front. Biosci. 11:344-355. (Pubitemid 43253497)
27. Wysocka, J., Swigut, T., Xiao, H., Milne, T. A., Kwon, S. Y., Landry, J., Kauer, M., Tackett, A. J., Chait, B. T., Badenhorst, P., Wu, C., and Allis, C. D. 2006b. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 442:86-90. (Pubitemid 44064214)
28. Xin, Z., Tachibana, M., Guggiari, M., Heard, E., Shinkai, Y., and Wagstaff, J. 2003. Role of histone methyltreansferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center. J. Biol. Chem. 278:14996-15000. (Pubitemid 36799831)
29. Yoon, K., Hwangbo, B., Kim, I., Park, S., Kim, H., Kee, H., Lee, J., Jang, Y., Park, J., and Lee, J. 2006. Novel polymorphism in the SUV39H2 histone methyltransferase and the risk of lung cancer. Carcinogenesis 27:2217-2222. (Pubitemid 44644810)