Toxicity of areca nut ingredients: Activation of CHK1/CHK2, induction of cell cycle arrest, and regulation of MMP-9 and TIMPs production in SAS epithelial cells

Head and Neck

Volumn 35, Issue 9, 2013, Pages 1295-1302

  Chang, Mei Chi ^a   Chan, Chiu Po ^b   Wang, Wei Ting ^c   Chang, Bei En ^c   Lee, Jang Jaer ^d   Tseng, Shuei Kuen ^d   Yeung, Sin Yuet ^b   Hahn, Liang Jiunn ^d   Jeng, Jiiang Huei ^d  

^a CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

areca nut; arecoline; betel quid; checkpoint kinase; chemical carcinogenesis; metalloproteinase 9; tissue inhibitors of metalloproteinases

Indexed keywords

ARECOLINE; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; GELATINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

APOPTOSIS; ARTICLE; BETEL NUT; CARCINOGENESIS; CELL CYCLE ARREST; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SYNTHESIS; EPITHELIUM CELL; GENOTOXICITY; MOUTH CANCER; PRIORITY JOURNAL;

ARECA NUT; ARECOLINE; BETEL QUID; CHECKPOINT KINASE; CHEMICAL CARCINOGENESIS; METALLOPROTEINASE-9; TISSUE INHIBITORS OF METALLOPROTEINASES;

ARECA; ARECOLINE; CELL CYCLE; CELLS, CULTURED; CHECKPOINT KINASE 2; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; MATRIX METALLOPROTEINASE 9; NUTS; PLANT EXTRACTS; PROTEIN KINASES; TISSUE INHIBITOR OF METALLOPROTEINASES; TONGUE NEOPLASMS;

EID: 84883055477     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.23119     Document Type: Article

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