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Volumn 3 SEP, Issue , 2013, Pages

Getting to know ovarian cancer ascites: Opportunities for targeted therapy-based translational research

Author keywords

Ascites; Chemoresistance; Cytokines; Metastasis; Ovarian carcinoma; Recurrence

Indexed keywords

ANGIOGENIN; ANGIOPOIETIN; BEVACIZUMAB; EPIDERMAL GROWTH FACTOR; FAS LIGAND; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; MATRIX METALLOPROTEINASE; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPROTEGERIN; PLATELET DERIVED GROWTH FACTOR; RANTES; SCATTER FACTOR; SOMATOMEDIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UROKINASE RECEPTOR; VASCULOTROPIN;

EID: 84891138385     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2013.00256     Document Type: Article
Times cited : (352)

References (134)
  • 1
    • 77956495728 scopus 로고    scopus 로고
    • Ovarian cancer development and metastasis
    • doi: 10.2353/ajpath.2010.100105
    • Lengyel E. Ovarian cancer development and metastasis. Am J Pathol (2010) 177(3):1053-64. doi: 10.2353/ajpath.2010.100105
    • (2010) Am J Pathol , vol.177 , Issue.3 , pp. 1053-1064
    • Lengyel, E.1
  • 2
    • 84875419233 scopus 로고    scopus 로고
    • Meeting the challenge of ascites in ovarian cancer: new avenues for therapy and research
    • doi:10.1038/nrc3432
    • Kipps E, Tan DS, Kaye SB. Meeting the challenge of ascites in ovarian cancer: new avenues for therapy and research. Nat Rev Cancer (2013) 13(4):273-82. doi:10.1038/nrc3432
    • (2013) Nat Rev Cancer , vol.13 , Issue.4 , pp. 273-282
    • Kipps, E.1    Tan, D.S.2    Kaye, S.B.3
  • 3
    • 34447298354 scopus 로고    scopus 로고
    • Pattern and prognostic factors in patients with malignant ascites: a retrospective study
    • doi:10.1093/annonc/mdl499
    • Ayantunde AA, Parsons SL. Pattern and prognostic factors in patients with malignant ascites: a retrospective study. Ann Oncol (2007) 18(5):945-9. doi:10.1093/annonc/mdl499
    • (2007) Ann Oncol , vol.18 , Issue.5 , pp. 945-949
    • Ayantunde, A.A.1    Parsons, S.L.2
  • 4
    • 18944402351 scopus 로고    scopus 로고
    • Ascites induces modulation of alpha6beta1 integrin and urokinase plasminogen activator receptor expression and associated functions in ovarian carcinoma
    • doi:10.1038/sj.bjc.6602495
    • Ahmed N, Riley C, Oliva K, Rice G, Quinn M. Ascites induces modulation of alpha6beta1 integrin and urokinase plasminogen activator receptor expression and associated functions in ovarian carcinoma. Br J Cancer (2005) 92(8):1475-85. doi:10.1038/sj.bjc.6602495
    • (2005) Br J Cancer , vol.92 , Issue.8 , pp. 1475-1485
    • Ahmed, N.1    Riley, C.2    Oliva, K.3    Rice, G.4    Quinn, M.5
  • 5
    • 0141995796 scopus 로고    scopus 로고
    • Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid
    • doi:10.1002/path.1441
    • Ahmed N, Riley C, Oliva K, Stutt E, Rice GE, Quinn MA. Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid. J Pathol (2003) 201(2):229-37. doi:10.1002/path.1441
    • (2003) J Pathol , vol.201 , Issue.2 , pp. 229-237
    • Ahmed, N.1    Riley, C.2    Oliva, K.3    Stutt, E.4    Rice, G.E.5    Quinn, M.A.6
  • 6
    • 34548092116 scopus 로고    scopus 로고
    • Malignant ascites protect against TRAIL-induced apoptosis by activating the PI3K/Akt pathway in human ovarian carcinoma cells
    • doi:10.1002/ijc.22840
    • Lane D, Robert V, Grondin R, Rancourt C, Piche A. Malignant ascites protect against TRAIL-induced apoptosis by activating the PI3K/Akt pathway in human ovarian carcinoma cells. Int J Cancer (2007) 121(6):1227-37. doi:10.1002/ijc.22840
    • (2007) Int J Cancer , vol.121 , Issue.6 , pp. 1227-1237
    • Lane, D.1    Robert, V.2    Grondin, R.3    Rancourt, C.4    Piche, A.5
  • 7
    • 18344380440 scopus 로고    scopus 로고
    • Ovarian cancer metastasis: integrating insights from disparate model organisms
    • doi:10.1038/nrc1611
    • Naora H, Montell DJ. Ovarian cancer metastasis: integrating insights from disparate model organisms. Nat Rev Cancer (2005) 5(5):355-66. doi:10.1038/nrc1611
    • (2005) Nat Rev Cancer , vol.5 , Issue.5 , pp. 355-366
    • Naora, H.1    Montell, D.J.2
  • 8
    • 35848946387 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: an exception to the norm
    • doi:10.1002/jcp.21240
    • Ahmed N, Thompson EW, Quinn MA. Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: an exception to the norm. J Cell Physiol (2007) 213(3):581-8. doi:10.1002/jcp.21240
    • (2007) J Cell Physiol , vol.213 , Issue.3 , pp. 581-588
    • Ahmed, N.1    Thompson, E.W.2    Quinn, M.A.3
  • 9
    • 33644838275 scopus 로고    scopus 로고
    • Disaggregation and invasion of ovarian carcinoma ascites spheroids
    • doi:10.1186/1479-5876-4-6
    • Burleson KM, Boente MP, Pambuccian SE, Skubitz AP. Disaggregation and invasion of ovarian carcinoma ascites spheroids. J Transl Med (2006) 4:6. doi:10.1186/1479-5876-4-6
    • (2006) J Transl Med , vol.4 , pp. 6
    • Burleson, K.M.1    Boente, M.P.2    Pambuccian, S.E.3    Skubitz, A.P.4
  • 10
    • 62749197305 scopus 로고    scopus 로고
    • Multicellular spheroids in ovarian cancer metastases: biology and pathology
    • doi:10.1016/j.ygyno.2008.11.032
    • Shield K, Ackland ML, Ahmed N, Rice GE. Multicellular spheroids in ovarian cancer metastases: biology and pathology. Gynecol Oncol (2009) 113(1):143-8. doi:10.1016/j.ygyno.2008.11.032
    • (2009) Gynecol Oncol , vol.113 , Issue.1 , pp. 143-148
    • Shield, K.1    Ackland, M.L.2    Ahmed, N.3    Rice, G.E.4
  • 11
    • 33750312322 scopus 로고    scopus 로고
    • Mechanisms of transcoelomic metastasis in ovarian cancer
    • doi:10.1016/S1470-2045(06)70939-1
    • Tan DS, Agarwal R, Kaye SB. Mechanisms of transcoelomic metastasis in ovarian cancer. Lancet Oncol (2006) 7(11):925-34. doi:10.1016/S1470-2045(06)70939-1
    • (2006) Lancet Oncol , vol.7 , Issue.11 , pp. 925-934
    • Tan, D.S.1    Agarwal, R.2    Kaye, S.B.3
  • 12
    • 69249235702 scopus 로고    scopus 로고
    • Dissemination of intraperitoneal ovarian cancer: discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model
    • doi:10.1016/j.critrevonc.2008.12.003
    • Feki A, Berardi P, Bellingan G, Major A, Krause KH, Petignat P, et al. Dissemination of intraperitoneal ovarian cancer: discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model. Crit Rev Oncol Hematol (2009) 72(1):1-9. doi:10.1016/j.critrevonc.2008.12.003
    • (2009) Crit Rev Oncol Hematol , vol.72 , Issue.1 , pp. 1-9
    • Feki, A.1    Berardi, P.2    Bellingan, G.3    Major, A.4    Krause, K.H.5    Petignat, P.6
  • 13
    • 0031767724 scopus 로고    scopus 로고
    • Diagnosing ascitic etiology on a biochemical basis
    • Bansal S, Kaur K, Bansal AK. Diagnosing ascitic etiology on a biochemical basis. Hepatogastroenterology (1998) 45(23):1673-7.
    • (1998) Hepatogastroenterology , vol.45 , Issue.23 , pp. 1673-1677
    • Bansal, S.1    Kaur, K.2    Bansal, A.K.3
  • 14
    • 0023766008 scopus 로고
    • Ascitic fluid analysis in malignancy-related ascites
    • doi:10.1002/hep.1840080521
    • Runyon BA, Hoefs JC, Morgan TR. Ascitic fluid analysis in malignancy-related ascites. Hepatology (1988) 8(5):1104-9. doi:10.1002/hep.1840080521
    • (1988) Hepatology , vol.8 , Issue.5 , pp. 1104-1109
    • Runyon, B.A.1    Hoefs, J.C.2    Morgan, T.R.3
  • 15
    • 0041912752 scopus 로고    scopus 로고
    • Can patients with relapsed, previously untreated, stage I epithelial ovarian cancer be successfully treated with salvage therapy?
    • doi:10.1200/JCO.2003.06.119
    • Kolomainen DF, A'Hern R, Coxon FY, Fisher C, King DM, Blake PR, et al. Can patients with relapsed, previously untreated, stage I epithelial ovarian cancer be successfully treated with salvage therapy? J Clin Oncol (2003) 21(16):3113-8. doi:10.1200/JCO.2003.06.119
    • (2003) J Clin Oncol , vol.21 , Issue.16 , pp. 3113-3118
    • Kolomainen, D.F.1    A'Hern, R.2    Coxon, F.Y.3    Fisher, C.4    King, D.M.5    Blake, P.R.6
  • 16
    • 0016195162 scopus 로고
    • Lymphatic drainage of the peritoneal cavity and its significance in ovarian cancer
    • Feldman GB, Knapp RC. Lymphatic drainage of the peritoneal cavity and its significance in ovarian cancer. Am J Obstet Gynecol (1974) 119(7):991-4.
    • (1974) Am J Obstet Gynecol , vol.119 , Issue.7 , pp. 991-994
    • Feldman, G.B.1    Knapp, R.C.2
  • 17
    • 2942577573 scopus 로고    scopus 로고
    • Malignant ascites: past, present, and future
    • doi:10.1016/j.jamcollsurg.2004.01.035
    • Adam RA, Adam YG. Malignant ascites: past, present, and future. J Am Coll Surg (2004) 198(6):999-1011. doi:10.1016/j.jamcollsurg.2004.01.035
    • (2004) J Am Coll Surg , vol.198 , Issue.6 , pp. 999-1011
    • Adam, R.A.1    Adam, Y.G.2
  • 18
    • 0015385809 scopus 로고
    • The role of lymphatic obstruction in the formation of ascites in a murine ovarian carcinoma
    • Feldman GB, Knapp RC, Order SE, Hellman S. The role of lymphatic obstruction in the formation of ascites in a murine ovarian carcinoma. Cancer Res (1972) 32(8):1663-6.
    • (1972) Cancer Res , vol.32 , Issue.8 , pp. 1663-1666
    • Feldman, G.B.1    Knapp, R.C.2    Order, S.E.3    Hellman, S.4
  • 19
    • 0038724683 scopus 로고    scopus 로고
    • Intraperitoneal cancer dissemination: mechanisms of the patterns of spread
    • doi:10.1023/A:1023791229361
    • Carmignani CP, Sugarbaker TA, Bromley CM, Sugarbaker PH. Intraperitoneal cancer dissemination: mechanisms of the patterns of spread. Cancer Metastasis Rev (2003) 22(4):465-72. doi:10.1023/A:1023791229361
    • (2003) Cancer Metastasis Rev , vol.22 , Issue.4 , pp. 465-472
    • Carmignani, C.P.1    Sugarbaker, T.A.2    Bromley, C.M.3    Sugarbaker, P.H.4
  • 20
    • 84878456311 scopus 로고    scopus 로고
    • Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules
    • doi:10.1073/pnas.1216989110
    • Rizvi I, Gurkan UA, Tasoglu S, Alagic N, Celli JP, Mensah LB, et al. Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules. Proc Natl Acad Sci U S A (2013) 110(22):E1974-83. doi:10.1073/pnas.1216989110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.22
    • Rizvi, I.1    Gurkan, U.A.2    Tasoglu, S.3    Alagic, N.4    Celli, J.P.5    Mensah, L.B.6
  • 22
    • 0025011698 scopus 로고
    • Ascitic fluid from human ovarian cancer patients contains growth factors necessary for intraperitoneal growth of human ovarian adenocarcinoma cells
    • doi:10.1172/JCI114784
    • Mills GB, May C, Hill M, Campbell S, Shaw P, Marks A. Ascitic fluid from human ovarian cancer patients contains growth factors necessary for intraperitoneal growth of human ovarian adenocarcinoma cells. J Clin Invest (1990) 86(3):851-5. doi:10.1172/JCI114784
    • (1990) J Clin Invest , vol.86 , Issue.3 , pp. 851-855
    • Mills, G.B.1    May, C.2    Hill, M.3    Campbell, S.4    Shaw, P.5    Marks, A.6
  • 23
    • 0023860289 scopus 로고
    • A putative new growth factor in ascitic fluid from ovarian cancer patients: identification, characterization, and mechanism of action
    • Mills GB, May C, McGill M, Roifman CM, Mellors A. A putative new growth factor in ascitic fluid from ovarian cancer patients: identification, characterization, and mechanism of action. Cancer Res (1988) 48(5):1066-71.
    • (1988) Cancer Res , vol.48 , Issue.5 , pp. 1066-1071
    • Mills, G.B.1    May, C.2    McGill, M.3    Roifman, C.M.4    Mellors, A.5
  • 24
    • 84870299455 scopus 로고    scopus 로고
    • Profiling of cytokines in human epithelial ovarian cancer ascites
    • Matte I, Lane D, Laplante C, Rancourt C, Piche A. Profiling of cytokines in human epithelial ovarian cancer ascites. Am J Cancer Res (2012) 2(5):566-80.
    • (2012) Am J Cancer Res , vol.2 , Issue.5 , pp. 566-580
    • Matte, I.1    Lane, D.2    Laplante, C.3    Rancourt, C.4    Piche, A.5
  • 25
    • 84868676376 scopus 로고    scopus 로고
    • Osteoprotegerin (OPG) protects ovarian cancer cells from TRAIL-induced apoptosis but does not contribute to malignant ascites-mediated attenuation of TRAIL-induced apoptosis
    • doi:10.1186/1757-2215-5-34
    • Lane D, Matte I, Rancourt C, Piche A. Osteoprotegerin (OPG) protects ovarian cancer cells from TRAIL-induced apoptosis but does not contribute to malignant ascites-mediated attenuation of TRAIL-induced apoptosis. J Ovarian Res (2012) 5(1):34. doi:10.1186/1757-2215-5-34
    • (2012) J Ovarian Res , vol.5 , Issue.1 , pp. 34
    • Lane, D.1    Matte, I.2    Rancourt, C.3    Piche, A.4
  • 26
    • 12244271468 scopus 로고    scopus 로고
    • Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells
    • doi:10.1210/jc.2004-0297
    • Choi JH, Park SH, Leung PC, Choi KC. Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells. J Clin Endocrinol Metab (2005) 90(1):207-10. doi:10.1210/jc.2004-0297
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.1 , pp. 207-210
    • Choi, J.H.1    Park, S.H.2    Leung, P.C.3    Choi, K.C.4
  • 27
    • 0034763562 scopus 로고    scopus 로고
    • Cytokines and immune response in the tumor microenvironment
    • Mocellin S, Wang E, Marincola FM. Cytokines and immune response in the tumor microenvironment. J Immunother (2001) 24(5):392-407.
    • (2001) J Immunother , vol.24 , Issue.5 , pp. 392-407
    • Mocellin, S.1    Wang, E.2    Marincola, F.M.3
  • 28
    • 0037769110 scopus 로고    scopus 로고
    • Dendritic cells in immunity and tolerance-do they display opposite functions?
    • doi:10.1016/S1074-7613(03)00182-1
    • Moser M. Dendritic cells in immunity and tolerance-do they display opposite functions? Immunity (2003) 19(1):5-8. doi:10.1016/S1074-7613(03)00182-1
    • (2003) Immunity , vol.19 , Issue.1 , pp. 5-8
    • Moser, M.1
  • 29
    • 0035062021 scopus 로고    scopus 로고
    • Interleukin-10 and the interleukin-10 receptor
    • doi:10.1146/annurev.immunol.19.1.683
    • Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol (2001) 19:683-765. doi:10.1146/annurev.immunol.19.1.683
    • (2001) Annu Rev Immunol , vol.19 , pp. 683-765
    • Moore, K.W.1    de Waal Malefyt, R.2    Coffman, R.L.3    O'Garra, A.4
  • 31
    • 79551610187 scopus 로고    scopus 로고
    • Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity
    • doi:10.3892/or.2010.1119
    • Peng P, Yan Y, Keng S. Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity. Oncol Rep (2011) 25(3):749-62. doi:10.3892/or.2010.1119
    • (2011) Oncol Rep , vol.25 , Issue.3 , pp. 749-762
    • Peng, P.1    Yan, Y.2    Keng, S.3
  • 32
    • 84864842768 scopus 로고    scopus 로고
    • Molecular identification of GD3 as a suppressor of the innate immune response in ovarian cancer
    • doi:10.1158/0008-5472.CAN-11-2695
    • Webb TJ, Li X, Giuntoli RL II, Lopez PH, Heuser C, Schnaar RL, et al. Molecular identification of GD3 as a suppressor of the innate immune response in ovarian cancer. Cancer Res (2012) 72(15):3744-52. doi:10.1158/0008-5472.CAN-11-2695
    • (2012) Cancer Res , vol.72 , Issue.15 , pp. 3744-3752
    • Webb, T.J.1    Li, X.2    Giuntoli I.I, R.L.3    Lopez, P.H.4    Heuser, C.5    Schnaar, R.L.6
  • 33
    • 76749085709 scopus 로고    scopus 로고
    • MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
    • doi:10.1186/1476-4598-9-11
    • Gubbels JA, Felder M, Horibata S, Belisle JA, Kapur A, Holden H, et al. MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells. Mol Cancer (2010) 9:11. doi:10.1186/1476-4598-9-11
    • (2010) Mol Cancer , vol.9 , pp. 11
    • Gubbels, J.A.1    Felder, M.2    Horibata, S.3    Belisle, J.A.4    Kapur, A.5    Holden, H.6
  • 34
    • 0033973947 scopus 로고    scopus 로고
    • IL-6 production in ovarian carcinoma is associated with histiotype and biological characteristics of the tumour and influences local immunity
    • Kryczek I, Grybos M, Karabon L, Klimczak A, Lange A. IL-6 production in ovarian carcinoma is associated with histiotype and biological characteristics of the tumour and influences local immunity. Br J Cancer (2000) 82(3):621-8.
    • (2000) Br J Cancer , vol.82 , Issue.3 , pp. 621-628
    • Kryczek, I.1    Grybos, M.2    Karabon, L.3    Klimczak, A.4    Lange, A.5
  • 35
    • 6744262234 scopus 로고    scopus 로고
    • Cytokines IL-1beta, IL-2, IL-6, IL-8, MCP-1, GM-CSF and TNFalpha in patients with epithelial ovarian cancer and their relationship to treatment with paclitaxel
    • doi:10.1046/j.1525-1438.2000.00003.x
    • Penson RT, Kronish K, Duan Z, Feller AJ, Stark P, Cook SE, et al. Cytokines IL-1beta, IL-2, IL-6, IL-8, MCP-1, GM-CSF and TNFalpha in patients with epithelial ovarian cancer and their relationship to treatment with paclitaxel. Int J Gynecol Cancer (2000) 10(1):33-41. doi:10.1046/j.1525-1438.2000.00003.x
    • (2000) Int J Gynecol Cancer , vol.10 , Issue.1 , pp. 33-41
    • Penson, R.T.1    Kronish, K.2    Duan, Z.3    Feller, A.J.4    Stark, P.5    Cook, S.E.6
  • 36
    • 0034306969 scopus 로고    scopus 로고
    • Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8
    • Huang S, Robinson JB, Deguzman A, Bucana CD, Fidler IJ. Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. Cancer Res (2000) 60(19):5334-9.
    • (2000) Cancer Res , vol.60 , Issue.19 , pp. 5334-5339
    • Huang, S.1    Robinson, J.B.2    Deguzman, A.3    Bucana, C.D.4    Fidler, I.J.5
  • 37
    • 0031049172 scopus 로고    scopus 로고
    • Effects of interleukin-6 on in vitro cell attachment, migration and invasion of human ovarian carcinoma
    • Obata NH, Tamakoshi K, Shibata K, Kikkawa F, Tomoda Y. Effects of interleukin-6 on in vitro cell attachment, migration and invasion of human ovarian carcinoma. Anticancer Res (1997) 17(1A):337-42.
    • (1997) Anticancer Res , vol.17 , Issue.1 A , pp. 337-342
    • Obata, N.H.1    Tamakoshi, K.2    Shibata, K.3    Kikkawa, F.4    Tomoda, Y.5
  • 38
    • 0037123348 scopus 로고    scopus 로고
    • Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells
    • doi:10.1093/jnci/94.8.617
    • Syed V, Ulinski G, Mok SC, Ho SM. Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells. J Natl Cancer Inst (2002) 94(8):617-29. doi:10.1093/jnci/94.8.617
    • (2002) J Natl Cancer Inst , vol.94 , Issue.8 , pp. 617-629
    • Syed, V.1    Ulinski, G.2    Mok, S.C.3    Ho, S.M.4
  • 39
    • 77953611991 scopus 로고    scopus 로고
    • Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells
    • doi:10.1016/j.canlet.2010.02.019
    • Wang Y, Niu XL, Qu Y, Wu J, Zhu YQ, Sun WJ, et al. Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells. Cancer Lett (2010) 295(1):110-23. doi:10.1016/j.canlet.2010.02.019
    • (2010) Cancer Lett , vol.295 , Issue.1 , pp. 110-123
    • Wang, Y.1    Niu, X.L.2    Qu, Y.3    Wu, J.4    Zhu, Y.Q.5    Sun, W.J.6
  • 40
    • 84887911347 scopus 로고    scopus 로고
    • Platinum-resistance in ovarian cancer cells is mediated by IL-6 secretion via the increased expression of its target cIAP-2
    • doi:10.1007/s00109-012-0946-4
    • Cohen S, Bruchim I, Graiver D, Evron Z, Oron-Karni V, Pasmanik-Chor M, et al. Platinum-resistance in ovarian cancer cells is mediated by IL-6 secretion via the increased expression of its target cIAP-2. J Mol Med (Berl) (2013) 91(3):357-68. doi:10.1007/s00109-012-0946-4
    • (2013) J Mol Med (Berl) , vol.91 , Issue.3 , pp. 357-368
    • Cohen, S.1    Bruchim, I.2    Graiver, D.3    Evron, Z.4    Oron-Karni, V.5    Pasmanik-Chor, M.6
  • 41
    • 28244475975 scopus 로고    scopus 로고
    • Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine
    • doi:10.1158/0008-5472.CAN-05-0623
    • Nilsson MB, Langley RR, Fidler IJ. Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine. Cancer Res (2005) 65(23):10794-800. doi:10.1158/0008-5472.CAN-05-0623
    • (2005) Cancer Res , vol.65 , Issue.23 , pp. 10794-10800
    • Nilsson, M.B.1    Langley, R.R.2    Fidler, I.J.3
  • 42
    • 0031194467 scopus 로고    scopus 로고
    • Serum evaluation of interleukin 6 in ovarian cancer patients
    • doi:10.1006/gyno.1997.4726
    • Temfer C, Zeisler H, Sliutz G, Haeusler G, Hanzal E, Kainz C. Serum evaluation of interleukin 6 in ovarian cancer patients. Gynecol Oncol (1997) 66(1):27-30. doi:10.1006/gyno.1997.4726
    • (1997) Gynecol Oncol , vol.66 , Issue.1 , pp. 27-30
    • Temfer, C.1    Zeisler, H.2    Sliutz, G.3    Haeusler, G.4    Hanzal, E.5    Kainz, C.6
  • 43
    • 0028871101 scopus 로고
    • Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer
    • doi:10.1038/bjc.1995.71
    • Scambia G, Testa U, Benedetti PP, Foti E, Martucci R, Gadducci A, et al. Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer. Br J Cancer (1995) 71(2):354-6. doi:10.1038/bjc.1995.71
    • (1995) Br J Cancer , vol.71 , Issue.2 , pp. 354-356
    • Scambia, G.1    Testa, U.2    Benedetti, P.P.3    Foti, E.4    Martucci, R.5    Gadducci, A.6
  • 44
    • 79957466111 scopus 로고    scopus 로고
    • Prognostic significance of IL-6 and Il-8 ascites levels in ovarian cancer patients
    • doi:10.1186/1471-2407-11-210
    • Lane D, Matte I, Rancourt C, Pinche A. Prognostic significance of IL-6 and Il-8 ascites levels in ovarian cancer patients. BMC Cancer (2011) 11:210. doi:10.1186/1471-2407-11-210
    • (2011) BMC Cancer , vol.11 , pp. 210
    • Lane, D.1    Matte, I.2    Rancourt, C.3    Pinche, A.4
  • 45
    • 0028203595 scopus 로고
    • Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer
    • doi:10.1002/1097-0142(19940401)73:7<1882::AID-CNCR2820730718>3.0.CO;2-R
    • Plante M, Rubin SC, Wong GY, Federici MG, Finstad CL, Gasti GA. Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer. Cancer (1994) 73(7):1882-8. doi:10.1002/1097-0142(19940401)73:7<1882::AID-CNCR2820730718>3.0.CO;2-R
    • (1994) Cancer , vol.73 , Issue.7 , pp. 1882-1888
    • Plante, M.1    Rubin, S.C.2    Wong, G.Y.3    Federici, M.G.4    Finstad, C.L.5    Gasti, G.A.6
  • 46
    • 0032865917 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF) in ovarian epithelial tumour fluids stimulates the migration of ovarian carcinoma cells
    • doi:10.1002/(SICI)1097-0215(19991112)83:4<476::AID-IJC7>3.0.CO;2-V
    • Sowter HM, Corps AN, Smith SK. Hepatocyte growth factor (HGF) in ovarian epithelial tumour fluids stimulates the migration of ovarian carcinoma cells. Int J Cancer (1999) 83(4):476-80. doi:10.1002/(SICI)1097-0215(19991112)83:4<476::AID-IJC7>3.0.CO;2-V
    • (1999) Int J Cancer , vol.83 , Issue.4 , pp. 476-480
    • Sowter, H.M.1    Corps, A.N.2    Smith, S.K.3
  • 47
    • 10744225477 scopus 로고    scopus 로고
    • Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells
    • doi:10.1074/jbc.M306662200
    • Fang X, Yu S, Bast RC, Liu S, Xu HJ, Hu SX, et al. Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells. J Biol Chem (2004) 279(10):9653-61. doi:10.1074/jbc.M306662200
    • (2004) J Biol Chem , vol.279 , Issue.10 , pp. 9653-9661
    • Fang, X.1    Yu, S.2    Bast, R.C.3    Liu, S.4    Xu, H.J.5    Hu, S.X.6
  • 48
    • 0035897531 scopus 로고    scopus 로고
    • Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells
    • doi:10.1093/jnci/93.10.762
    • Hu YL, Tee MK, Goetzl EJ, Auersperg N, Mills GB, Ferrara N, et al. Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells. J Natl Cancer Inst (2001) 93(10):762-8. doi:10.1093/jnci/93.10.762
    • (2001) J Natl Cancer Inst , vol.93 , Issue.10 , pp. 762-768
    • Hu, Y.L.1    Tee, M.K.2    Goetzl, E.J.3    Auersperg, N.4    Mills, G.B.5    Ferrara, N.6
  • 49
    • 84864078672 scopus 로고    scopus 로고
    • Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells
    • doi:10.1074/jbc.M112.340083
    • Mukherjee A, Wu J, Barbour S, Fang X. Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells. J Biol Chem (2012) 287(30):24990-5000. doi:10.1074/jbc.M112.340083
    • (2012) J Biol Chem , vol.287 , Issue.30 , pp. 24990-25000
    • Mukherjee, A.1    Wu, J.2    Barbour, S.3    Fang, X.4
  • 50
    • 84861024878 scopus 로고    scopus 로고
    • Lysophosphatidic Acid disrupts junctional integrity and epithelial cohesion in ovarian cancer cells
    • doi:10.1155/2012/501492
    • Liu Y, Burkhalter R, Symowicz J, Chaffin K, Ellerbroek S, Stack MS. Lysophosphatidic Acid disrupts junctional integrity and epithelial cohesion in ovarian cancer cells. J Oncol (2012) 2012:501492. doi:10.1155/2012/501492
    • (2012) J Oncol , vol.2012 , pp. 501492
    • Liu, Y.1    Burkhalter, R.2    Symowicz, J.3    Chaffin, K.4    Ellerbroek, S.5    Stack, M.S.6
  • 51
    • 1842850792 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and interleukin-8 are associated with poor prognosis in epithelial ovarian cancer patients
    • doi:10.1016/j.clinbiochem.2004.01.014
    • Kassim SK, El-Salahy EM, Fayed ST, Helal SA, Helal T, Azzam Eel D, et al. Vascular endothelial growth factor and interleukin-8 are associated with poor prognosis in epithelial ovarian cancer patients. Clin Biochem (2004) 37(5):363-9. doi:10.1016/j.clinbiochem.2004.01.014
    • (2004) Clin Biochem , vol.37 , Issue.5 , pp. 363-369
    • Kassim, S.K.1    El-Salahy, E.M.2    Fayed, S.T.3    Helal, S.A.4    Helal, T.5    Azzam Eel, D.6
  • 52
    • 0030923795 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in early stage ovarian carcinoma
    • doi:10.1002/(SICI)1097-0142(19970701)80:1<98::AID-CNCR13>3.0.CO;2-A
    • Paley PJ, Staskus KA, Gebhard K, Mohanraj D, Twiggs LB, Carson LF, et al. Vascular endothelial growth factor expression in early stage ovarian carcinoma. Cancer (1997) 80(1):98-106. doi:10.1002/(SICI)1097-0142(19970701)80:1<98::AID-CNCR13>3.0.CO;2-A
    • (1997) Cancer , vol.80 , Issue.1 , pp. 98-106
    • Paley, P.J.1    Staskus, K.A.2    Gebhard, K.3    Mohanraj, D.4    Twiggs, L.B.5    Carson, L.F.6
  • 54
    • 0345060442 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model
    • Byrne AT, Ross L, Holash J, Nakanishi M, Hu L, Hofmann JI, et al. Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model. Clin Cancer Res (2003) 9(15):5721-8.
    • (2003) Clin Cancer Res , vol.9 , Issue.15 , pp. 5721-5728
    • Byrne, A.T.1    Ross, L.2    Holash, J.3    Nakanishi, M.4    Hu, L.5    Hofmann, J.I.6
  • 55
    • 84865680246 scopus 로고    scopus 로고
    • VEGF induces ascites in ovarian cancer patients via increasing peritoneal permeability by downregulation of Claudin 5
    • doi:10.1016/j.ygyno.2012.05.002
    • Herr D, Sallmann A, Bekes I, Konrad R, Holzheu I, Kreienberg R, et al. VEGF induces ascites in ovarian cancer patients via increasing peritoneal permeability by downregulation of Claudin 5. Gynecol Oncol (2012) 127(1):210-6. doi:10.1016/j.ygyno.2012.05.002
    • (2012) Gynecol Oncol , vol.127 , Issue.1 , pp. 210-216
    • Herr, D.1    Sallmann, A.2    Bekes, I.3    Konrad, R.4    Holzheu, I.5    Kreienberg, R.6
  • 56
    • 0031825437 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells
    • Esser S, Lampugnani MG, Corada M, Dejana E, Risau W. Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells. J Cell Sci (1998) 111(Pt 13):1853-65.
    • (1998) J Cell Sci , vol.111 , Issue.PART 13 , pp. 1853-1865
    • Esser, S.1    Lampugnani, M.G.2    Corada, M.3    Dejana, E.4    Risau, W.5
  • 57
    • 79953648492 scopus 로고    scopus 로고
    • Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer
    • doi:10.1093/annonc/mdq708
    • Zweifel M, Jayson GC, Reed NS, Osborne R, Hassan B, Ledermann J, et al. Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer. Ann Oncol (2011) 22(9):2036-41. doi:10.1093/annonc/mdq708
    • (2011) Ann Oncol , vol.22 , Issue.9 , pp. 2036-2041
    • Zweifel, M.1    Jayson, G.C.2    Reed, N.S.3    Osborne, R.4    Hassan, B.5    Ledermann, J.6
  • 58
    • 84891074926 scopus 로고    scopus 로고
    • Current status of bevacizumab in advanced ovarian cancer
    • doi:10.2147/OTT.S46301
    • Tomao F, Papa A, Rossi L, Caruso D, Panici PB, Venezia M, et al. Current status of bevacizumab in advanced ovarian cancer. Onco Targets Ther (2013) 6:889-99. doi:10.2147/OTT.S46301
    • (2013) Onco Targets Ther , vol.6 , pp. 889-899
    • Tomao, F.1    Papa, A.2    Rossi, L.3    Caruso, D.4    Panici, P.B.5    Venezia, M.6
  • 59
    • 0035740826 scopus 로고    scopus 로고
    • Ovarian carcinoma and serous effusions. Changing views regarding tumor progression and review of current literature
    • Davidson B. Ovarian carcinoma and serous effusions. Changing views regarding tumor progression and review of current literature. Anal Cell Pathol (2001) 23(3-4):107-28.
    • (2001) Anal Cell Pathol , vol.23 , Issue.3-4 , pp. 107-128
    • Davidson, B.1
  • 60
    • 84867320871 scopus 로고    scopus 로고
    • Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: molecular phenotype of chemoresistant ovarian tumors
    • doi:10.1371/journal.pone.0046858
    • Latifi A, Luwor RB, Bilandzic M, Nazaretian S, Stenvers K, Pyman J, et al. Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: molecular phenotype of chemoresistant ovarian tumors. PLoS One (2012) 7(10):e46858. doi:10.1371/journal.pone.0046858
    • (2012) PLoS One , vol.7 , Issue.10
    • Latifi, A.1    Luwor, R.B.2    Bilandzic, M.3    Nazaretian, S.4    Stenvers, K.5    Pyman, J.6
  • 62
    • 77952855239 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition and cancer stem cell-like phenotypes facilitate chemoresistance in recurrent ovarian cancer
    • doi:10.2174/156800910791190175
    • Ahmed N, Abubaker K, Findlay J, Quinn M. Epithelial mesenchymal transition and cancer stem cell-like phenotypes facilitate chemoresistance in recurrent ovarian cancer. Curr Cancer Drug Targets (2010) 10(3):268-78. doi:10.2174/156800910791190175
    • (2010) Curr Cancer Drug Targets , vol.10 , Issue.3 , pp. 268-278
    • Ahmed, N.1    Abubaker, K.2    Findlay, J.3    Quinn, M.4
  • 63
    • 47549085187 scopus 로고    scopus 로고
    • Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression
    • doi:10.1007/s10585-008-9171-5
    • Hudson LG, Zeineldin R, Stack MS. Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression. Clin Exp Metastasis (2008) 25(6):643-55. doi:10.1007/s10585-008-9171-5
    • (2008) Clin Exp Metastasis , vol.25 , Issue.6 , pp. 643-655
    • Hudson, L.G.1    Zeineldin, R.2    Stack, M.S.3
  • 64
    • 0033800091 scopus 로고    scopus 로고
    • Multicellular resistance: a paradigm for clinical resistance?
    • doi:10.1016/S1040-8428(00)00086-X
    • Desoize B, Jardillier J. Multicellular resistance: a paradigm for clinical resistance? Crit Rev Oncol Hematol (2000) 36(2-3):193-207. doi:10.1016/S1040-8428(00)00086-X
    • (2000) Crit Rev Oncol Hematol , vol.36 , Issue.2-3 , pp. 193-207
    • Desoize, B.1    Jardillier, J.2
  • 65
    • 84876489727 scopus 로고    scopus 로고
    • Cancer stem cells: the challenges ahead
    • doi:10.1038/ncb2717
    • Medema JP. Cancer stem cells: the challenges ahead. Nat Cell Biol (2013) 15(4):338-44. doi:10.1038/ncb2717
    • (2013) Nat Cell Biol , vol.15 , Issue.4 , pp. 338-344
    • Medema, J.P.1
  • 66
  • 67
    • 84869445970 scopus 로고    scopus 로고
    • Cancerous ovarian stem cells: obscure targets for therapy but relevant to chemoresistance
    • doi:10.1002/jcb.24317
    • Ahmed N, Abubaker K, Findlay J, Quinn M. Cancerous ovarian stem cells: obscure targets for therapy but relevant to chemoresistance. J Cell Biochem (2013) 114(1):21-34. doi:10.1002/jcb.24317
    • (2013) J Cell Biochem , vol.114 , Issue.1 , pp. 21-34
    • Ahmed, N.1    Abubaker, K.2    Findlay, J.3    Quinn, M.4
  • 68
    • 79961006281 scopus 로고    scopus 로고
    • Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production
    • doi:10.1172/JCI45273
    • McLean K, Gong Y, Choi Y, Deng N, Yang K, Bai S, et al. Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest (2011) 121(8):3206-19. doi:10.1172/JCI45273
    • (2011) J Clin Invest , vol.121 , Issue.8 , pp. 3206-3219
    • McLean, K.1    Gong, Y.2    Choi, Y.3    Deng, N.4    Yang, K.5    Bai, S.6
  • 69
    • 84906963524 scopus 로고    scopus 로고
    • Ovarian cancer stem cells: molecular concepts and relevance as therapeutic targets
    • doi:10.1016/j.mam.2013.06.002
    • Ahmed N, Abubaker K, Findlay JK. Ovarian cancer stem cells: molecular concepts and relevance as therapeutic targets. Mol Aspects Med (2013). doi:10.1016/j.mam.2013.06.002
    • (2013) Mol Aspects Med
    • Ahmed, N.1    Abubaker, K.2    Findlay, J.K.3
  • 70
    • 41149148789 scopus 로고    scopus 로고
    • The impact of T-cell immunity on ovarian cancer outcomes
    • doi:10.1111/j.1600-065X.2008.00614.x
    • Nelson BH. The impact of T-cell immunity on ovarian cancer outcomes. Immunol Rev (2008) 222:101-16. doi:10.1111/j.1600-065X.2008.00614.x
    • (2008) Immunol Rev , vol.222 , pp. 101-116
    • Nelson, B.H.1
  • 71
    • 40749136616 scopus 로고    scopus 로고
    • Immunotherapy opportunities in ovarian cancer
    • doi:10.1586/14737140.8.2.243
    • Chu CS, Kim SH, June CH, Coukos G. Immunotherapy opportunities in ovarian cancer. Expert Rev Anticancer Ther (2008) 8(2):243-57. doi:10.1586/14737140.8.2.243
    • (2008) Expert Rev Anticancer Ther , vol.8 , Issue.2 , pp. 243-257
    • Chu, C.S.1    Kim, S.H.2    June, C.H.3    Coukos, G.4
  • 72
    • 78650973754 scopus 로고    scopus 로고
    • Polyfunctional T-cell responses are disrupted by the ovarian cancer ascites environment and only partially restored by clinically relevant cytokines
    • doi:10.1371/journal.pone.0015625
    • Tran E, Nielsen JS, Wick DA, Ng AV, Johnson LD, Nesslinger NJ, et al. Polyfunctional T-cell responses are disrupted by the ovarian cancer ascites environment and only partially restored by clinically relevant cytokines. PLoS One (2010) 5(12):e15625. doi:10.1371/journal.pone.0015625
    • (2010) PLoS One , vol.5 , Issue.12
    • Tran, E.1    Nielsen, J.S.2    Wick, D.A.3    Ng, A.V.4    Johnson, L.D.5    Nesslinger, N.J.6
  • 73
    • 77953409587 scopus 로고    scopus 로고
    • Ovarian tumor-induced T cell suppression is alleviated by vascular leukocyte depletion
    • Peter S, Bak G, Hart K, Berwin B. Ovarian tumor-induced T cell suppression is alleviated by vascular leukocyte depletion. Transl Oncol (2009) 2(4):291-9.
    • (2009) Transl Oncol , vol.2 , Issue.4 , pp. 291-299
    • Peter, S.1    Bak, G.2    Hart, K.3    Berwin, B.4
  • 74
    • 68549132400 scopus 로고    scopus 로고
    • Ovarian cancer-associated ascites demonstrates altered immune environment: implications for antitumor immunity
    • Giuntoli RL II, Webb TJ, Zoso A, Rogers O, Diaz-Montes TP, Bristow RE, et al. Ovarian cancer-associated ascites demonstrates altered immune environment: implications for antitumor immunity. Anticancer Res (2009) 29(8):2875-84.
    • (2009) Anticancer Res , vol.29 , Issue.8 , pp. 2875-2884
    • Giuntoli I.I, R.L.1    Webb, T.J.2    Zoso, A.3    Rogers, O.4    Diaz-Montes, T.P.5    Bristow, R.E.6
  • 75
    • 58149303099 scopus 로고    scopus 로고
    • Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer
    • doi:10.1007/s00262-008-0583-5
    • Leffers N, Gooden MJ, de Jong RA, Hoogeboom BN, ten Hoor KA, Hollema H, et al. Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer. Cancer Immunol Immunother (2009) 58(3):449-59. doi:10.1007/s00262-008-0583-5
    • (2009) Cancer Immunol Immunother , vol.58 , Issue.3 , pp. 449-459
    • Leffers, N.1    Gooden, M.J.2    de Jong, R.A.3    Hoogeboom, B.N.4    ten Hoor, K.A.5    Hollema, H.6
  • 76
    • 34250159834 scopus 로고    scopus 로고
    • Significant differences of lymphocytes isolated from ascites of patients with ovarian cancer compared to blood and tumor lymphocytes. Association of CD3+CD56+ cells with platinum resistance
    • doi:10.1016/j.ygyno.2007.02.029
    • Bamias A, Tsiatas ML, Kafantari E, Liakou C, Rodolakis A, Voulgaris Z, et al. Significant differences of lymphocytes isolated from ascites of patients with ovarian cancer compared to blood and tumor lymphocytes. Association of CD3+CD56+ cells with platinum resistance. Gynecol Oncol (2007) 106(1):75-81. doi:10.1016/j.ygyno.2007.02.029
    • (2007) Gynecol Oncol , vol.106 , Issue.1 , pp. 75-81
    • Bamias, A.1    Tsiatas, M.L.2    Kafantari, E.3    Liakou, C.4    Rodolakis, A.5    Voulgaris, Z.6
  • 77
    • 69849107597 scopus 로고    scopus 로고
    • Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
    • doi:10.1182/blood-2009-03-208249
    • Kryczek I, Banerjee M, Cheng P, Vatan L, Szeliga W, Wei S, et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood (2009) 114(6):1141-9. doi:10.1182/blood-2009-03-208249
    • (2009) Blood , vol.114 , Issue.6 , pp. 1141-1149
    • Kryczek, I.1    Banerjee, M.2    Cheng, P.3    Vatan, L.4    Szeliga, W.5    Wei, S.6
  • 78
    • 84885951882 scopus 로고    scopus 로고
    • Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse
    • doi:10.1002/ijc.28335
    • Reinartz S, Schumann T, Finkernagel F, Wortmann A, Jansen JM, Meissner W, et al. Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse. Int J Cancer (2013). doi:10.1002/ijc.28335
    • (2013) Int J Cancer
    • Reinartz, S.1    Schumann, T.2    Finkernagel, F.3    Wortmann, A.4    Jansen, J.M.5    Meissner, W.6
  • 79
    • 20444485236 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma
    • doi:10.1158/0008-5472.CAN-04-4043
    • Wei S, Kryczek I, Zou L, Daniel B, Cheng P, Mottram P, et al. Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma. Cancer Res (2005) 65(12):5020-6. doi:10.1158/0008-5472.CAN-04-4043
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 5020-5026
    • Wei, S.1    Kryczek, I.2    Zou, L.3    Daniel, B.4    Cheng, P.5    Mottram, P.6
  • 80
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • doi:10.1038/nm1093
    • Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med (2004) 10(9):942-9. doi:10.1038/nm1093
    • (2004) Nat Med , vol.10 , Issue.9 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6
  • 81
    • 4143064951 scopus 로고    scopus 로고
    • Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer
    • doi:10.1158/0008-5472.CAN-04-1272
    • Curiel TJ, Cheng P, Mottram P, Alvarez X, Moons L, Evdemon-Hogan M, et al. Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer. Cancer Res (2004) 64(16):5535-8. doi:10.1158/0008-5472.CAN-04-1272
    • (2004) Cancer Res , vol.64 , Issue.16 , pp. 5535-5538
    • Curiel, T.J.1    Cheng, P.2    Mottram, P.3    Alvarez, X.4    Moons, L.5    Evdemon-Hogan, M.6
  • 82
    • 66149118659 scopus 로고    scopus 로고
    • Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism
    • doi:10.1158/0008-5472.CAN-08-2826
    • Norian LA, Rodriguez PC, O'Mara LA, Zabaleta J, Ochoa AC, Cella M, et al. Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism. Cancer Res (2009) 69(7):3086-94. doi:10.1158/0008-5472.CAN-08-2826
    • (2009) Cancer Res , vol.69 , Issue.7 , pp. 3086-3094
    • Norian, L.A.1    Rodriguez, P.C.2    O'Mara, L.A.3    Zabaleta, J.4    Ochoa, A.C.5    Cella, M.6
  • 83
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • doi:10.1038/nri2506
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol (2009) 9(3):162-74. doi:10.1038/nri2506
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 85
    • 79951852902 scopus 로고    scopus 로고
    • Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion
    • doi:10.1016/j.canlet.2011.01.011
    • Zhang Y, Tang H, Cai J, Zhang T, Guo J, Feng D, et al. Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion. Cancer Lett (2011) 303(1):47-55. doi:10.1016/j.canlet.2011.01.011
    • (2011) Cancer Lett , vol.303 , Issue.1 , pp. 47-55
    • Zhang, Y.1    Tang, H.2    Cai, J.3    Zhang, T.4    Guo, J.5    Feng, D.6
  • 86
    • 84855393328 scopus 로고    scopus 로고
    • Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness
    • doi:10.1093/carcin/bgr230
    • Cai J, Tang H, Xu L, Wang X, Yang C, Ruan S, et al. Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness. Carcinogenesis (2012) 33(1):20-9. doi:10.1093/carcin/bgr230
    • (2012) Carcinogenesis , vol.33 , Issue.1 , pp. 20-29
    • Cai, J.1    Tang, H.2    Xu, L.3    Wang, X.4    Yang, C.5    Ruan, S.6
  • 87
    • 84875684114 scopus 로고    scopus 로고
    • Interleukin-1beta promotes ovarian tumorigenesis through a p53/NF-kappaB-mediated inflammatory response in stromal fibroblasts
    • Schauer IG, Zhang J, Xing Z, Guo X, Mercado-Uribe I, Sood AK, et al. Interleukin-1beta promotes ovarian tumorigenesis through a p53/NF-kappaB-mediated inflammatory response in stromal fibroblasts. Neoplasia (2013) 15(4):409-20.
    • (2013) Neoplasia , vol.15 , Issue.4 , pp. 409-420
    • Schauer, I.G.1    Zhang, J.2    Xing, Z.3    Guo, X.4    Mercado-Uribe, I.5    Sood, A.K.6
  • 88
    • 64549145804 scopus 로고    scopus 로고
    • Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression
    • doi:10.1371/journal.pone.0004992
    • Spaeth EL, Dembinski JL, Sasser AK, Watson K, Klopp A, Hall B, et al. Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression. PLoS One (2009) 4(4):e4992. doi:10.1371/journal.pone.0004992
    • (2009) PLoS One , vol.4 , Issue.4
    • Spaeth, E.L.1    Dembinski, J.L.2    Sasser, A.K.3    Watson, K.4    Klopp, A.5    Hall, B.6
  • 89
    • 84870895812 scopus 로고    scopus 로고
    • Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment
    • doi:10.1039/c2lc40887b
    • Businaro L, De Ninno A, Schiavoni G, Lucarini V, Ciasca G, Gerardino A, et al. Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment. Lab Chip (2013) 13(2):229-39. doi:10.1039/c2lc40887b
    • (2013) Lab Chip , vol.13 , Issue.2 , pp. 229-239
    • Businaro, L.1    De Ninno, A.2    Schiavoni, G.3    Lucarini, V.4    Ciasca, G.5    Gerardino, A.6
  • 90
    • 20444486841 scopus 로고    scopus 로고
    • Ovarian carcinoma cells and IL-1beta-activated human peritoneal mesothelial cells are possible sources of vascular endothelial growth factor in inflammatory and malignant peritoneal effusions
    • doi:10.1016/j.ygyno.2005.02.017
    • Stadlmann S, Amberger A, Pollheimer J, Gastl G, Offner FA, Margreiter R, et al. Ovarian carcinoma cells and IL-1beta-activated human peritoneal mesothelial cells are possible sources of vascular endothelial growth factor in inflammatory and malignant peritoneal effusions. Gynecol Oncol (2005) 97(3):784-9. doi:10.1016/j.ygyno.2005.02.017
    • (2005) Gynecol Oncol , vol.97 , Issue.3 , pp. 784-789
    • Stadlmann, S.1    Amberger, A.2    Pollheimer, J.3    Gastl, G.4    Offner, F.A.5    Margreiter, R.6
  • 91
    • 34848888380 scopus 로고    scopus 로고
    • Possible involvement of SDF-1alpha/CXCR4-DPPIV axis in TGF-beta1-induced enhancement of migratory potential in human peritoneal mesothelial cells
    • doi:10.1007/s00441-007-0455-x
    • Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F. Possible involvement of SDF-1alpha/CXCR4-DPPIV axis in TGF-beta1-induced enhancement of migratory potential in human peritoneal mesothelial cells. Cell Tissue Res (2007) 330(2):221-9. doi:10.1007/s00441-007-0455-x
    • (2007) Cell Tissue Res , vol.330 , Issue.2 , pp. 221-229
    • Kajiyama, H.1    Shibata, K.2    Ino, K.3    Nawa, A.4    Mizutani, S.5    Kikkawa, F.6
  • 92
    • 79955002720 scopus 로고    scopus 로고
    • Evidence for cancer stem cells contributing to the pathogenesis of ovarian cancer
    • doi:10.2741/3693
    • Curley MD, Garrett LA, Schorge JO, Foster R, Rueda BR. Evidence for cancer stem cells contributing to the pathogenesis of ovarian cancer. Front Biosci (2011) 16:368-92. doi:10.2741/3693
    • (2011) Front Biosci , vol.16 , pp. 368-392
    • Curley, M.D.1    Garrett, L.A.2    Schorge, J.O.3    Foster, R.4    Rueda, B.R.5
  • 93
    • 17144403478 scopus 로고    scopus 로고
    • Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer
    • Bapat SA, Mali AM, Koppikar CB, Kurrey NK. Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res (2005) 65(8):3025-9.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3025-3029
    • Bapat, S.A.1    Mali, A.M.2    Koppikar, C.B.3    Kurrey, N.K.4
  • 94
    • 49249091523 scopus 로고    scopus 로고
    • Identification and characterization of ovarian cancer-initiating cells from primary human tumors
    • doi:10.1158/0008-5472.CAN-08-0364
    • Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res (2008) 68(11):4311-20. doi:10.1158/0008-5472.CAN-08-0364
    • (2008) Cancer Res , vol.68 , Issue.11 , pp. 4311-4320
    • Zhang, S.1    Balch, C.2    Chan, M.W.3    Lai, H.C.4    Matei, D.5    Schilder, J.M.6
  • 97
    • 84865056040 scopus 로고    scopus 로고
    • Protein markers of cancer-associated fibroblasts and tumor-initiating cells reveal subpopulations in freshly isolated ovarian cancer ascites
    • doi:10.1186/1471-2407-12-359
    • Wintzell M, Hjerpe E, Avall Lundqvist E, Shoshan M. Protein markers of cancer-associated fibroblasts and tumor-initiating cells reveal subpopulations in freshly isolated ovarian cancer ascites. BMC Cancer (2012) 12:359. doi:10.1186/1471-2407-12-359
    • (2012) BMC Cancer , vol.12 , pp. 359
    • Wintzell, M.1    Hjerpe, E.2    Avall Lundqvist, E.3    Shoshan, M.4
  • 98
    • 33846029123 scopus 로고    scopus 로고
    • A perivascular niche for brain tumor stem cells
    • doi:10.1016/j.ccr.2006.11.020
    • Calabrese C, Poppleton H, Kocak M, Hogg TL, Fuller C, Hamner B, et al. A perivascular niche for brain tumor stem cells. Cancer Cell (2007) 11(1):69-82. doi:10.1016/j.ccr.2006.11.020
    • (2007) Cancer Cell , vol.11 , Issue.1 , pp. 69-82
    • Calabrese, C.1    Poppleton, H.2    Kocak, M.3    Hogg, T.L.4    Fuller, C.5    Hamner, B.6
  • 99
    • 84880291315 scopus 로고    scopus 로고
    • Evaluating cell lines as tumour models by comparison of genomic profiles
    • doi:10.1038/ncomms3126
    • Domcke S, Sinha R, Levine DA, Sander C, Schultz N. Evaluating cell lines as tumour models by comparison of genomic profiles. Nat Commun (2013) 4:2126. doi:10.1038/ncomms3126
    • (2013) Nat Commun , vol.4 , pp. 2126
    • Domcke, S.1    Sinha, R.2    Levine, D.A.3    Sander, C.4    Schultz, N.5
  • 100
    • 34447345507 scopus 로고    scopus 로고
    • Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients
    • doi:10.1038/nprot.2006.328
    • Shepherd TG, Theriault BL, Campbell EJ, Nachtigal MW. Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients. Nat Protoc (2006) 1(6):2643-9. doi:10.1038/nprot.2006.328
    • (2006) Nat Protoc , vol.1 , Issue.6 , pp. 2643-2649
    • Shepherd, T.G.1    Theriault, B.L.2    Campbell, E.J.3    Nachtigal, M.W.4
  • 101
    • 84857019139 scopus 로고    scopus 로고
    • Isolation and characterization of stromal progenitor cells from ascites of patients with epithelial ovarian adenocarcinoma
    • doi:10.1186/1423-0127-19-23
    • Ho CM, Chang SF, Hsiao CC, Chien TY, Shih DT. Isolation and characterization of stromal progenitor cells from ascites of patients with epithelial ovarian adenocarcinoma. J Biomed Sci (2012) 19:23. doi:10.1186/1423-0127-19-23
    • (2012) J Biomed Sci , vol.19 , pp. 23
    • Ho, C.M.1    Chang, S.F.2    Hsiao, C.C.3    Chien, T.Y.4    Shih, D.T.5
  • 102
    • 84855857047 scopus 로고    scopus 로고
    • Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer
    • doi:10.1371/journal.pone.0029079
    • Vathipadiekal V, Saxena D, Mok SC, Hauschka PV, Ozbun L, Birrer MJ. Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer. PLoS One (2012) 7(1):e29079. doi:10.1371/journal.pone.0029079
    • (2012) PLoS One , vol.7 , Issue.1
    • Vathipadiekal, V.1    Saxena, D.2    Mok, S.C.3    Hauschka, P.V.4    Ozbun, L.5    Birrer, M.J.6
  • 103
    • 77950862035 scopus 로고    scopus 로고
    • Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant
    • doi:10.1038/sj.bjc.6605626
    • Hu L, McArthur C, Jaffe RB. Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant. Br J Cancer (2010) 102(8):1276-83. doi:10.1038/sj.bjc.6605626
    • (2010) Br J Cancer , vol.102 , Issue.8 , pp. 1276-1283
    • Hu, L.1    McArthur, C.2    Jaffe, R.B.3
  • 104
    • 77954196772 scopus 로고    scopus 로고
    • Human ovarian cancer stem cells
    • doi:10.1530/REP-09-0389
    • Bapat SA. Human ovarian cancer stem cells. Reproduction (2010) 140(1):33-41. doi:10.1530/REP-09-0389
    • (2010) Reproduction , vol.140 , Issue.1 , pp. 33-41
    • Bapat, S.A.1
  • 105
    • 84875320058 scopus 로고    scopus 로고
    • Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
    • doi:10.1186/1476-4598-12-24
    • Abubaker K, Latifi A, Luwor R, Nazaretian S, Zhu H, Quinn MA, et al. Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden. Mol Cancer (2013) 12(1):24. doi:10.1186/1476-4598-12-24
    • (2013) Mol Cancer , vol.12 , Issue.1 , pp. 24
    • Abubaker, K.1    Latifi, A.2    Luwor, R.3    Nazaretian, S.4    Zhu, H.5    Quinn, M.A.6
  • 106
    • 60749103183 scopus 로고    scopus 로고
    • Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance
    • doi:10.4161/cc.8.1.7533
    • Alvero AB, Chen R, Fu HH, Montagna M, Schwartz PE, Rutherford T, et al. Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell Cycle (2009) 8(1):158-66. doi:10.4161/cc.8.1.7533
    • (2009) Cell Cycle , vol.8 , Issue.1 , pp. 158-166
    • Alvero, A.B.1    Chen, R.2    Fu, H.H.3    Montagna, M.4    Schwartz, P.E.5    Rutherford, T.6
  • 107
    • 80053211466 scopus 로고    scopus 로고
    • Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile
    • doi:10.1002/jcb.23199
    • Latifi A, Abubaker K, Castrechini N, Ward AC, Liongue C, Dobill F, et al. Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile. J Cell Biochem (2011) 112:2850-64. doi:10.1002/jcb.23199
    • (2011) J Cell Biochem , vol.112 , pp. 2850-2864
    • Latifi, A.1    Abubaker, K.2    Castrechini, N.3    Ward, A.C.4    Liongue, C.5    Dobill, F.6
  • 108
    • 84887492120 scopus 로고    scopus 로고
    • Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical sub-classes in high-grade serous ovarian carcinoma
    • doi:10.1002/ijc.28371
    • Tang Z, Ow GS, Thiery JP, Ivshina AV, Kuznetsov VA. Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical sub-classes in high-grade serous ovarian carcinoma. Int J Cancer (2013). doi:10.1002/ijc.28371
    • (2013) Int J Cancer
    • Tang, Z.1    Ow, G.S.2    Thiery, J.P.3    Ivshina, A.V.4    Kuznetsov, V.A.5
  • 109
    • 84866251102 scopus 로고    scopus 로고
    • Advances in the formation, use and understanding of multi-cellular spheroids
    • doi:10.1517/14712598.2012.707181
    • Achilli TM, Meyer J, Morgan JR. Advances in the formation, use and understanding of multi-cellular spheroids. Expert Opin Biol Ther (2012) 12(10):1347-60. doi:10.1517/14712598.2012.707181
    • (2012) Expert Opin Biol Ther , vol.12 , Issue.10 , pp. 1347-1360
    • Achilli, T.M.1    Meyer, J.2    Morgan, J.R.3
  • 110
    • 84865453325 scopus 로고    scopus 로고
    • The multicellular tumor spheroid model for high-throughput cancer drug discovery
    • doi:10.1517/17460441.2012.708334
    • LaBarbera DV, Reid BG, Yoo BH. The multicellular tumor spheroid model for high-throughput cancer drug discovery. Expert Opin Drug Discov (2012) 7(9):819-30. doi:10.1517/17460441.2012.708334
    • (2012) Expert Opin Drug Discov , vol.7 , Issue.9 , pp. 819-830
    • LaBarbera, D.V.1    Reid, B.G.2    Yoo, B.H.3
  • 111
    • 34547141141 scopus 로고    scopus 로고
    • Alpha2beta1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis
    • doi:10.1186/1477-3163-6-11
    • Shield K, Riley C, Quinn MA, Rice GE, Ackland ML, Ahmed N. Alpha2beta1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis. J Carcinog (2007) 6:11. doi:10.1186/1477-3163-6-11
    • (2007) J Carcinog , vol.6 , pp. 11
    • Shield, K.1    Riley, C.2    Quinn, M.A.3    Rice, G.E.4    Ackland, M.L.5    Ahmed, N.6
  • 112
    • 84859579201 scopus 로고    scopus 로고
    • Myxoma virus-mediated oncolysis of ascites-derived human ovarian cancer cells and spheroids is impacted by differential AKT activity
    • doi:10.1016/j.ygyno.2012.01.048
    • Correa RJ, Komar M, Tong JG, Sivapragasam M, Rahman MM, McFadden G, et al. Myxoma virus-mediated oncolysis of ascites-derived human ovarian cancer cells and spheroids is impacted by differential AKT activity. Gynecol Oncol (2012) 125(2):441-50. doi:10.1016/j.ygyno.2012.01.048
    • (2012) Gynecol Oncol , vol.125 , Issue.2 , pp. 441-450
    • Correa, R.J.1    Komar, M.2    Tong, J.G.3    Sivapragasam, M.4    Rahman, M.M.5    McFadden, G.6
  • 113
    • 84862313384 scopus 로고    scopus 로고
    • Cell-cell and cell-matrix dynamics in intraperitoneal cancer metastasis
    • doi:10.1007/s10555-012-9351-2
    • Sodek KL, Murphy KJ, Brown TJ, Ringuette MJ. Cell-cell and cell-matrix dynamics in intraperitoneal cancer metastasis. Cancer Metastasis Rev (2012) 31(1-2):397-414. doi:10.1007/s10555-012-9351-2
    • (2012) Cancer Metastasis Rev , vol.31 , Issue.1-2 , pp. 397-414
    • Sodek, K.L.1    Murphy, K.J.2    Brown, T.J.3    Ringuette, M.J.4
  • 114
    • 73949158295 scopus 로고    scopus 로고
    • Peritoneal adhesion and angiogenesis in ovarian carcinoma are inversely regulated by hyaluronan: the role of gonadotropins
    • Tzuman YC, Sapoznik S, Granot D, Nevo N, Neeman M. Peritoneal adhesion and angiogenesis in ovarian carcinoma are inversely regulated by hyaluronan: the role of gonadotropins. Neoplasia (2010) 12(1):51-60.
    • (2010) Neoplasia , vol.12 , Issue.1 , pp. 51-60
    • Tzuman, Y.C.1    Sapoznik, S.2    Granot, D.3    Nevo, N.4    Neeman, M.5
  • 115
    • 84857849160 scopus 로고    scopus 로고
    • In vitro mesothelial clearance assay that models the early steps of ovarian cancer metastasis
    • doi:10.3791/3888
    • Davidowitz RA, Iwanicki MP, Brugge JS. In vitro mesothelial clearance assay that models the early steps of ovarian cancer metastasis. J Vis Exp (2012) 60:e3888. doi:10.3791/3888
    • (2012) J Vis Exp , vol.60
    • Davidowitz, R.A.1    Iwanicki, M.P.2    Brugge, J.S.3
  • 116
    • 66949174192 scopus 로고    scopus 로고
    • Organotypic models of metastasis: a three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis
    • doi:10.1007/978-0-387-98094-2_16
    • Kenny HA, Dogan S, Zillhardt M, Mitra AK, Yamada SD, Krausz T, et al. Organotypic models of metastasis: a three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis. Cancer Treat Res (2009) 149:335-51. doi:10.1007/978-0-387-98094-2_16
    • (2009) Cancer Treat Res , vol.149 , pp. 335-351
    • Kenny, H.A.1    Dogan, S.2    Zillhardt, M.3    Mitra, A.K.4    Yamada, S.D.5    Krausz, T.6
  • 117
    • 81255157465 scopus 로고    scopus 로고
    • Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
    • doi:10.1038/nm.2492
    • Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med (2011) 17(11):1498-503. doi:10.1038/nm.2492
    • (2011) Nat Med , vol.17 , Issue.11 , pp. 1498-1503
    • Nieman, K.M.1    Kenny, H.A.2    Penicka, C.V.3    Ladanyi, A.4    Buell-Gutbrod, R.5    Zillhardt, M.R.6
  • 118
    • 62449220684 scopus 로고    scopus 로고
    • MMP-2 functions as an early response protein in ovarian cancer metastasis
    • doi:10.4161/cc.8.5.7703
    • Kenny HA, Lengyel E. MMP-2 functions as an early response protein in ovarian cancer metastasis. Cell Cycle (2009) 8(5):683-8. doi:10.4161/cc.8.5.7703
    • (2009) Cell Cycle , vol.8 , Issue.5 , pp. 683-688
    • Kenny, H.A.1    Lengyel, E.2
  • 119
    • 69449096005 scopus 로고    scopus 로고
    • Heterogeneity in cancer: cancer stem cells versus clonal evolution
    • doi:10.1016/j.cell.2009.08.017
    • Shackleton M, Quintana E, Fearon ER, Morrison SJ. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell (2009) 138(5):822-9. doi:10.1016/j.cell.2009.08.017
    • (2009) Cell , vol.138 , Issue.5 , pp. 822-829
    • Shackleton, M.1    Quintana, E.2    Fearon, E.R.3    Morrison, S.J.4
  • 120
    • 58849134940 scopus 로고    scopus 로고
    • Niche-dependent tumorigenic capacity of malignant ovarian ascites-derived cancer cell subpopulations
    • doi:10.1158/1078-0432.CCR-08-1233
    • Katz E, Skorecki K, Tzukerman M. Niche-dependent tumorigenic capacity of malignant ovarian ascites-derived cancer cell subpopulations. Clin Cancer Res (2009) 15(1):70-80. doi:10.1158/1078-0432.CCR-08-1233
    • (2009) Clin Cancer Res , vol.15 , Issue.1 , pp. 70-80
    • Katz, E.1    Skorecki, K.2    Tzukerman, M.3
  • 121
    • 19944423801 scopus 로고    scopus 로고
    • Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers
    • doi:10.1007/s10585-004-5768-5
    • Burleson KM, Hansen LK, Skubitz AP. Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers. Clin Exp Metastasis (2004) 21(8):685-97. doi:10.1007/s10585-004-5768-5
    • (2004) Clin Exp Metastasis , vol.21 , Issue.8 , pp. 685-697
    • Burleson, K.M.1    Hansen, L.K.2    Skubitz, A.P.3
  • 122
    • 81755174100 scopus 로고    scopus 로고
    • Clinical relevance of multidrug resistance gene expression in ovarian serous carcinoma effusions
    • doi:10.1021/mp200240a
    • Gillet JP, Wang J, Calcagno AM, Green LJ, Varma S, Bunkholt Elstrand M, et al. Clinical relevance of multidrug resistance gene expression in ovarian serous carcinoma effusions. Mol Pharm (2011) 8(6):2080-8. doi:10.1021/mp200240a
    • (2011) Mol Pharm , vol.8 , Issue.6 , pp. 2080-2088
    • Gillet, J.P.1    Wang, J.2    Calcagno, A.M.3    Green, L.J.4    Varma, S.5    Bunkholt Elstrand, M.6
  • 123
    • 28444458895 scopus 로고    scopus 로고
    • Proteomic tracking of serum protein isoforms as screening biomarkers of ovarian cancer
    • doi:10.1002/pmic.200401321
    • Ahmed N, Oliva KT, Barker G, Hoffmann P, Reeve S, Smith IA, et al. Proteomic tracking of serum protein isoforms as screening biomarkers of ovarian cancer. Proteomics (2005) 5(17):4625-36. doi:10.1002/pmic.200401321
    • (2005) Proteomics , vol.5 , Issue.17 , pp. 4625-4636
    • Ahmed, N.1    Oliva, K.T.2    Barker, G.3    Hoffmann, P.4    Reeve, S.5    Smith, I.A.6
  • 124
    • 32944461237 scopus 로고    scopus 로고
    • Proteomic analysis of malignant ovarian cancer effusions as a tool for biologic and prognostic profiling
    • doi:10.1158/1078-0432.CCR-05-2516
    • Davidson B, Espina V, Steinberg SM, Florenes VA, Liotta LA, Kristensen GB, et al. Proteomic analysis of malignant ovarian cancer effusions as a tool for biologic and prognostic profiling. Clin Cancer Res (2006) 12(3 Pt 1):791-9. doi:10.1158/1078-0432.CCR-05-2516
    • (2006) Clin Cancer Res , vol.12 , Issue.3 PART 1 , pp. 791-799
    • Davidson, B.1    Espina, V.2    Steinberg, S.M.3    Florenes, V.A.4    Liotta, L.A.5    Kristensen, G.B.6
  • 125
    • 84863794715 scopus 로고    scopus 로고
    • The association of PI3 kinase signaling and chemoresistance in advanced ovarian cancer
    • doi:10.1158/1535-7163.MCT-11-0996
    • Carden CP, Stewart A, Thavasu P, Kipps E, Pope L, Crespo M, et al. The association of PI3 kinase signaling and chemoresistance in advanced ovarian cancer. Mol Cancer Ther (2012) 11(7):1609-17. doi:10.1158/1535-7163.MCT-11-0996
    • (2012) Mol Cancer Ther , vol.11 , Issue.7 , pp. 1609-1617
    • Carden, C.P.1    Stewart, A.2    Thavasu, P.3    Kipps, E.4    Pope, L.5    Crespo, M.6
  • 126
    • 84859416701 scopus 로고    scopus 로고
    • Dissecting "PI3Kness": the complexity of personalized therapy for ovarian cancer
    • doi:10.1158/2159-8290.CD-11-0323
    • Bast RC Jr, Mills GB. Dissecting "PI3Kness": the complexity of personalized therapy for ovarian cancer. Cancer Discov (2012) 2(1):16-8. doi:10.1158/2159-8290.CD-11-0323
    • (2012) Cancer Discov , vol.2 , Issue.1 , pp. 16-18
    • Bast Jr., R.C.1    Mills, G.B.2
  • 127
    • 68249096784 scopus 로고    scopus 로고
    • Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
    • doi:10.1038/ncb1909
    • Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol (2009) 11(8):973-9. doi:10.1038/ncb1909
    • (2009) Nat Cell Biol , vol.11 , Issue.8 , pp. 973-979
    • Rodier, F.1    Coppe, J.P.2    Patil, C.K.3    Hoeijmakers, W.A.4    Munoz, D.P.5    Raza, S.R.6
  • 128
    • 51649109943 scopus 로고    scopus 로고
    • Chemotherapeutic drugs and human tumor cells cytokine network
    • doi:10.1002/ijc.23732
    • Levina V, Su Y, Nolen B, Liu X, Gordin Y, Lee M, et al. Chemotherapeutic drugs and human tumor cells cytokine network. Int J Cancer (2008) 123(9):2031-40. doi:10.1002/ijc.23732
    • (2008) Int J Cancer , vol.123 , Issue.9 , pp. 2031-2040
    • Levina, V.1    Su, Y.2    Nolen, B.3    Liu, X.4    Gordin, Y.5    Lee, M.6
  • 129
    • 63649092087 scopus 로고    scopus 로고
    • Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
    • doi:10.1016/j.canlet.2008.12.028
    • Keller S, Konig AK, Marme F, Runz S, Wolterink S, Koensgen D, et al. Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes. Cancer Lett (2009) 278(1):73-81. doi:10.1016/j.canlet.2008.12.028
    • (2009) Cancer Lett , vol.278 , Issue.1 , pp. 73-81
    • Keller, S.1    Konig, A.K.2    Marme, F.3    Runz, S.4    Wolterink, S.5    Koensgen, D.6
  • 130
    • 36348935057 scopus 로고    scopus 로고
    • Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM
    • doi:10.1016/j.ygyno.2007.08.064
    • Runz S, Keller S, Rupp C, Stoeck A, Issa Y, Koensgen D, et al. Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM. Gynecol Oncol (2007) 107(3):563-71. doi:10.1016/j.ygyno.2007.08.064
    • (2007) Gynecol Oncol , vol.107 , Issue.3 , pp. 563-571
    • Runz, S.1    Keller, S.2    Rupp, C.3    Stoeck, A.4    Issa, Y.5    Koensgen, D.6
  • 131
    • 77953388922 scopus 로고    scopus 로고
    • The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer
    • doi:10.1186/1757-2215-3-1
    • Lane D, Matte I, Rancourt C, Piche A. The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer. J Ovarian Res (2010) 3:1. doi:10.1186/1757-2215-3-1
    • (2010) J Ovarian Res , vol.3 , pp. 1
    • Lane, D.1    Matte, I.2    Rancourt, C.3    Piche, A.4
  • 132
    • 79952641187 scopus 로고    scopus 로고
    • Activated T lymphocytes migrate toward the cathode of DC electric fields in microfluidic devices
    • doi:10.1039/c0lc00371a
    • Li J, Nandagopal S, Wu D, Romanuik SF, Paul K, Thomson DJ, et al. Activated T lymphocytes migrate toward the cathode of DC electric fields in microfluidic devices. Lab Chip (2011) 11(7):1298-304. doi:10.1039/c0lc00371a
    • (2011) Lab Chip , vol.11 , Issue.7 , pp. 1298-1304
    • Li, J.1    Nandagopal, S.2    Wu, D.3    Romanuik, S.F.4    Paul, K.5    Thomson, D.J.6
  • 134
    • 70449465250 scopus 로고    scopus 로고
    • Genomic and personalized medicine: foundations and applications
    • doi:10.1016/j.trsl.2009.09.005
    • Ginsburg GS, Willard HF. Genomic and personalized medicine: foundations and applications. Transl Res (2009) 154(6):277-87. doi:10.1016/j.trsl.2009.09.005
    • (2009) Transl Res , vol.154 , Issue.6 , pp. 277-287
    • Ginsburg, G.S.1    Willard, H.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.