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Volumn 8, Issue 1, 2013, Pages

The intricate relationship between microtubules and their associated motor proteins during axon growth and maintenance

Author keywords

Axons; Brain disorders; Cytoskeleton; Drosophila; Dynein; Growth cones; Kinesins; Microtubules; Transport

Indexed keywords

DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; MOLECULAR MOTOR;

EID: 84883509044     PISSN: None     EISSN: 17498104     Source Type: Journal    
DOI: 10.1186/1749-8104-8-17     Document Type: Review
Times cited : (64)

References (122)
  • 2
    • 79957090929 scopus 로고    scopus 로고
    • Hannibal's mules: the logistical limitations of Hannibal's army and the Battle of Cannae, 216 BC
    • Shean JF. Hannibal's mules: the logistical limitations of Hannibal's army and the Battle of Cannae, 216 BC. Zeitschrift für Alte Geschichte 1996, 45:159-187.
    • (1996) Zeitschrift für Alte Geschichte , vol.45 , pp. 159-187
    • Shean, J.F.1
  • 3
    • 65249107203 scopus 로고    scopus 로고
    • Microtubule assembly, organization and dynamics in axons and dendrites
    • Conde C, Caceres A. Microtubule assembly, organization and dynamics in axons and dendrites. Nat Rev Neurosci 2009, 10:319-332.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 319-332
    • Conde, C.1    Caceres, A.2
  • 4
    • 84857371961 scopus 로고    scopus 로고
    • Assembly of a new growth cone after axotomy: the precursor to axon regeneration
    • Bradke F, Fawcett JW, Spira ME. Assembly of a new growth cone after axotomy: the precursor to axon regeneration. Nat Rev Neurosci 2012, 13:183-193.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 183-193
    • Bradke, F.1    Fawcett, J.W.2    Spira, M.E.3
  • 6
    • 0038467307 scopus 로고    scopus 로고
    • Marked loss of myelinated nerve fibers in the human brain with age
    • 10.1002/cne.10714, 12794739
    • Marner L, Nyengaard JR, Tang Y, Pakkenberg B. Marked loss of myelinated nerve fibers in the human brain with age. J Comp Neurol 2003, 462:144-152. 10.1002/cne.10714, 12794739.
    • (2003) J Comp Neurol , vol.462 , pp. 144-152
    • Marner, L.1    Nyengaard, J.R.2    Tang, Y.3    Pakkenberg, B.4
  • 7
    • 84873053822 scopus 로고    scopus 로고
    • Axon pathology in age-related neurodegenerative disorders
    • Adalbert R, Coleman MP. Axon pathology in age-related neurodegenerative disorders. Neuropathol Appl Neurobiol 2012, 39:90-108.
    • (2012) Neuropathol Appl Neurobiol , vol.39 , pp. 90-108
    • Adalbert, R.1    Coleman, M.P.2
  • 8
    • 84869861937 scopus 로고    scopus 로고
    • Axonal transport and neurodegenerative disease: can we see the elephant?
    • 10.1016/j.pneurobio.2012.03.006, 22484448
    • Goldstein LS. Axonal transport and neurodegenerative disease: can we see the elephant?. Prog Neurobiol 2012, 99:186-190. 10.1016/j.pneurobio.2012.03.006, 22484448.
    • (2012) Prog Neurobiol , vol.99 , pp. 186-190
    • Goldstein, L.S.1
  • 9
    • 27644591304 scopus 로고    scopus 로고
    • Axon degeneration mechanisms: commonality amid diversity
    • 10.1038/nrn1788, 16224497
    • Coleman M. Axon degeneration mechanisms: commonality amid diversity. Nat Rev Neurosci 2005, 6:889-898. 10.1038/nrn1788, 16224497.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 889-898
    • Coleman, M.1
  • 10
    • 84876080780 scopus 로고    scopus 로고
    • Microtubule stability in the axon: new answers to an old mystery
    • 10.1016/j.neuron.2013.03.012, 23583103
    • Baas PW. Microtubule stability in the axon: new answers to an old mystery. Neuron 2013, 78:3-5. 10.1016/j.neuron.2013.03.012, 23583103.
    • (2013) Neuron , vol.78 , pp. 3-5
    • Baas, P.W.1
  • 11
    • 81855196008 scopus 로고    scopus 로고
    • Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions
    • 10.1038/nrm3227, 22086369
    • Janke C, Bulinski JC. Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions. Nat Rev Mol Cell Biol 2011, 12:773-786. 10.1038/nrm3227, 22086369.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 773-786
    • Janke, C.1    Bulinski, J.C.2
  • 12
    • 77955272733 scopus 로고    scopus 로고
    • Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton
    • 10.1016/j.tins.2010.05.001, 20541813
    • Janke C, Kneussel M. Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton. Trends Neurosci 2010, 33:362-372. 10.1016/j.tins.2010.05.001, 20541813.
    • (2010) Trends Neurosci , vol.33 , pp. 362-372
    • Janke, C.1    Kneussel, M.2
  • 13
    • 0028344617 scopus 로고
    • Changes in microtubule number and length during axon differentiation
    • Yu W, Baas PW. Changes in microtubule number and length during axon differentiation. J Neurosci 1994, 14:2818-2829.
    • (1994) J Neurosci , vol.14 , pp. 2818-2829
    • Yu, W.1    Baas, P.W.2
  • 14
    • 79955724181 scopus 로고    scopus 로고
    • Hooks and comets: the story of microtubule polarity orientation in the neuron
    • 10.1002/dneu.20818, 3151545, 21557497
    • Baas PW, Lin S. Hooks and comets: the story of microtubule polarity orientation in the neuron. Dev Neurobiol 2011, 71:403-418. 10.1002/dneu.20818, 3151545, 21557497.
    • (2011) Dev Neurobiol , vol.71 , pp. 403-418
    • Baas, P.W.1    Lin, S.2
  • 19
    • 79961105234 scopus 로고    scopus 로고
    • Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport
    • 10.1083/jcb.201104034, 3144414, 21768290
    • Nakata T, Niwa S, Okada Y, Perez F, Hirokawa N. Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport. J Cell Biol 2011, 194:245-255. 10.1083/jcb.201104034, 3144414, 21768290.
    • (2011) J Cell Biol , vol.194 , pp. 245-255
    • Nakata, T.1    Niwa, S.2    Okada, Y.3    Perez, F.4    Hirokawa, N.5
  • 20
    • 84880701139 scopus 로고    scopus 로고
    • Evolving tip structures can explain age-dependent microtubule catastrophe
    • 10.1016/j.cub.2013.05.059, 23831290
    • Coombes CE, Yamamoto A, Kenzie MR, Odde DJ, Gardner MK. Evolving tip structures can explain age-dependent microtubule catastrophe. Curr Biol 2013, 23:1342-1348. 10.1016/j.cub.2013.05.059, 23831290.
    • (2013) Curr Biol , vol.23 , pp. 1342-1348
    • Coombes, C.E.1    Yamamoto, A.2    Kenzie, M.R.3    Odde, D.J.4    Gardner, M.K.5
  • 21
    • 84876089948 scopus 로고    scopus 로고
    • Transglutaminase and polyamination of tubulin: posttranslational modification for stabilizing axonal microtubules
    • 10.1016/j.neuron.2013.01.036, 23583110
    • Song Y, Kirkpatrick LL, Schilling AB, Helseth DL, Chabot N, Keillor JW, Johnson GV, Brady ST. Transglutaminase and polyamination of tubulin: posttranslational modification for stabilizing axonal microtubules. Neuron 2013, 78:109-123. 10.1016/j.neuron.2013.01.036, 23583110.
    • (2013) Neuron , vol.78 , pp. 109-123
    • Song, Y.1    Kirkpatrick, L.L.2    Schilling, A.B.3    Helseth, D.L.4    Chabot, N.5    Keillor, J.W.6    Johnson, G.V.7    Brady, S.T.8
  • 22
    • 70349482318 scopus 로고    scopus 로고
    • Neuronal intermediate filaments and neurodegenerative disorders
    • 10.1016/j.brainresbull.2009.06.004, 19539727
    • Perrot R, Eyer J. Neuronal intermediate filaments and neurodegenerative disorders. Brain Res Bull 2009, 80:282-295. 10.1016/j.brainresbull.2009.06.004, 19539727.
    • (2009) Brain Res Bull , vol.80 , pp. 282-295
    • Perrot, R.1    Eyer, J.2
  • 23
    • 84880008533 scopus 로고    scopus 로고
    • Using fly genetics to dissect the cytoskeletal machinery of neurons during axonal growth and maintenance
    • 10.1242/jcs.126912, 23729743
    • Prokop A, Beaven R, Qu Y, Sánchez-Soriano N. Using fly genetics to dissect the cytoskeletal machinery of neurons during axonal growth and maintenance. J Cell Sci 2013, 126:2331-2341. 10.1242/jcs.126912, 23729743.
    • (2013) J Cell Sci , vol.126 , pp. 2331-2341
    • Prokop, A.1    Beaven, R.2    Qu, Y.3    Sánchez-Soriano, N.4
  • 24
    • 0035996975 scopus 로고    scopus 로고
    • Relating molecular flexibility to function: a case study of tubulin
    • 10.1016/S0006-3495(02)75199-0, 1302177, 12124255
    • Keskin O, Durell SR, Bahar I, Jernigan RL, Covell DG. Relating molecular flexibility to function: a case study of tubulin. Biophys J 2002, 83:663-680. 10.1016/S0006-3495(02)75199-0, 1302177, 12124255.
    • (2002) Biophys J , vol.83 , pp. 663-680
    • Keskin, O.1    Durell, S.R.2    Bahar, I.3    Jernigan, R.L.4    Covell, D.G.5
  • 25
    • 79957626260 scopus 로고    scopus 로고
    • Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations
    • 10.1016/j.gde.2011.01.003, 3100401, 21292473
    • Tischfield MA, Cederquist GY, Gupta ML, Engle EC. Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations. Curr Opin Genet Dev 2011, 21:286-294. 10.1016/j.gde.2011.01.003, 3100401, 21292473.
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 286-294
    • Tischfield, M.A.1    Cederquist, G.Y.2    Gupta, M.L.3    Engle, E.C.4
  • 26
    • 84878649079 scopus 로고    scopus 로고
    • (Beta)-Tubulin mutations that cause severe neuropathies disrupt axonal transport
    • 10.1038/emboj.2013.59, 23503589
    • Niwa S, Takahashi H, Hirokawa N. (Beta)-Tubulin mutations that cause severe neuropathies disrupt axonal transport. EMBO J 2013, 32:1352-1364. 10.1038/emboj.2013.59, 23503589.
    • (2013) EMBO J , vol.32 , pp. 1352-1364
    • Niwa, S.1    Takahashi, H.2    Hirokawa, N.3
  • 27
    • 34548081175 scopus 로고    scopus 로고
    • Progressive motor neuronopathy: a critical role of the tubulin chaperone TBCE in axonal tubulin routing from the Golgi apparatus
    • 10.1523/JNEUROSCI.1599-07.2007, 17699660
    • Schaefer MK, Schmalbruch H, Buhler E, Lopez C, Martin N, Guenet JL, Haase G. Progressive motor neuronopathy: a critical role of the tubulin chaperone TBCE in axonal tubulin routing from the Golgi apparatus. J Neurosci 2007, 27:8779-8789. 10.1523/JNEUROSCI.1599-07.2007, 17699660.
    • (2007) J Neurosci , vol.27 , pp. 8779-8789
    • Schaefer, M.K.1    Schmalbruch, H.2    Buhler, E.3    Lopez, C.4    Martin, N.5    Guenet, J.L.6    Haase, G.7
  • 28
    • 73949095432 scopus 로고    scopus 로고
    • Growth and elongation within and along the axon
    • 10.1002/dneu.20764, 19950193
    • Lamoureux P, Heidemann SR, Martzke NR, Miller KE. Growth and elongation within and along the axon. Dev Neurobiol 2010, 70:135-149. 10.1002/dneu.20764, 19950193.
    • (2010) Dev Neurobiol , vol.70 , pp. 135-149
    • Lamoureux, P.1    Heidemann, S.R.2    Martzke, N.R.3    Miller, K.E.4
  • 29
    • 84893191307 scopus 로고    scopus 로고
    • Drosophila growth cones advance by forward translocation of the neuronal cytoskeletal meshwork in vivo
    • in press
    • Roossien DH, Lamoureux P, van Vactor D, Miller KE. Drosophila growth cones advance by forward translocation of the neuronal cytoskeletal meshwork in vivo. PLoS One 2013, in press.
    • (2013) PLoS One
    • Roossien, D.H.1    Lamoureux, P.2    van Vactor, D.3    Miller, K.E.4
  • 30
    • 79960646720 scopus 로고    scopus 로고
    • The growth cone cytoskeleton in axon outgrowth and guidance
    • 10.1101/cshperspect.a001800, 3039926,3039926, 21106647
    • Dent EW, Gupton SL, Gertler FB. The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harb Perspect Biol 2011, 3:a001800. 10.1101/cshperspect.a001800, 3039926,3039926, 21106647.
    • (2011) Cold Spring Harb Perspect Biol , vol.3
    • Dent, E.W.1    Gupton, S.L.2    Gertler, F.B.3
  • 31
    • 67349086281 scopus 로고    scopus 로고
    • The trip of the tip: understanding the growth cone machinery
    • 10.1038/nrm2679, 2714171, 19373241
    • Lowery LA, van Vactor D. The trip of the tip: understanding the growth cone machinery. Nat Rev Mol Cell Biol 2009, 10:332-343. 10.1038/nrm2679, 2714171, 19373241.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 332-343
    • Lowery, L.A.1    van Vactor, D.2
  • 32
    • 41149156427 scopus 로고    scopus 로고
    • Tracking the ends: a dynamic protein network controls the fate of microtubule tips
    • 10.1038/nrm2369, 18322465
    • Akhmanova A, Steinmetz MO. Tracking the ends: a dynamic protein network controls the fate of microtubule tips. Nat Rev Mol Cell Biol 2008, 9:309-322. 10.1038/nrm2369, 18322465.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 309-322
    • Akhmanova, A.1    Steinmetz, M.O.2
  • 33
    • 84880675455 scopus 로고    scopus 로고
    • Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance
    • 10.1242/jcs.122184, 23641072
    • Qu C, Dwyer T, Shao Q, Yang T, Huang H, Liu G. Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance. J Cell Sci 2013, 126:3070-3081. 10.1242/jcs.122184, 23641072.
    • (2013) J Cell Sci , vol.126 , pp. 3070-3081
    • Qu, C.1    Dwyer, T.2    Shao, Q.3    Yang, T.4    Huang, H.5    Liu, G.6
  • 34
    • 78449269612 scopus 로고    scopus 로고
    • Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease
    • 10.1016/j.neuron.2010.09.039, 21092854
    • Hirokawa N, Niwa S, Tanaka Y. Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. Neuron 2010, 68:610-638. 10.1016/j.neuron.2010.09.039, 21092854.
    • (2010) Neuron , vol.68 , pp. 610-638
    • Hirokawa, N.1    Niwa, S.2    Tanaka, Y.3
  • 35
    • 84863222963 scopus 로고    scopus 로고
    • SnapShot: axonal transport
    • 10.1016/j.cell.2012.05.001, 22579292
    • Twelvetrees A, Hendricks AG, Holzbaur ELF. SnapShot: axonal transport. Cell 2012, 149:950-e951. 10.1016/j.cell.2012.05.001, 22579292.
    • (2012) Cell , vol.149
    • Twelvetrees, A.1    Hendricks, A.G.2    Holzbaur, E.L.F.3
  • 36
    • 80052510244 scopus 로고    scopus 로고
    • Cytoplasmic dynein
    • 10.1042/BST0391169, 21936784
    • Allan VJ. Cytoplasmic dynein. Biochem Soc Trans 2011, 39:1169-1178. 10.1042/BST0391169, 21936784.
    • (2011) Biochem Soc Trans , vol.39 , pp. 1169-1178
    • Allan, V.J.1
  • 38
    • 84876705861 scopus 로고    scopus 로고
    • Systematic dissection of dynein regulators in mitosis
    • 10.1083/jcb.201208098, 23589491
    • Raaijmakers JA, Tanenbaum ME, Medema RH. Systematic dissection of dynein regulators in mitosis. J Cell Biol 2013, 201:201-215. 10.1083/jcb.201208098, 23589491.
    • (2013) J Cell Biol , vol.201 , pp. 201-215
    • Raaijmakers, J.A.1    Tanenbaum, M.E.2    Medema, R.H.3
  • 39
    • 48249102303 scopus 로고    scopus 로고
    • Role of axonal transport in neurodegenerative diseases
    • 10.1146/annurev.neuro.31.061307.090711, 18558852
    • De Vos KJ, Grierson AJ, Ackerley S, Miller CC. Role of axonal transport in neurodegenerative diseases. Annu Rev Neurosci 2008, 31:151-173. 10.1146/annurev.neuro.31.061307.090711, 18558852.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 151-173
    • De Vos, K.J.1    Grierson, A.J.2    Ackerley, S.3    Miller, C.C.4
  • 40
    • 84875443717 scopus 로고    scopus 로고
    • Axonal transport deficits and neurodegenerative diseases
    • 10.1038/nrn3380, 23361386
    • Millecamps S, Julien JP. Axonal transport deficits and neurodegenerative diseases. Nat Rev Neurosci 2013, 14:161-176. 10.1038/nrn3380, 23361386.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 161-176
    • Millecamps, S.1    Julien, J.P.2
  • 41
    • 84856056846 scopus 로고    scopus 로고
    • Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration
    • 10.1038/nrg3141, 22218207
    • Sheng ZH, Cai Q. Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci 2012, 13:77-93. 10.1038/nrg3141, 22218207.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 77-93
    • Sheng, Z.H.1    Cai, Q.2
  • 43
    • 84863344880 scopus 로고    scopus 로고
    • KIF21A-mediated axonal transport and selective endocytosis underlie the polarized targeting of NCKX2
    • 10.1523/JNEUROSCI.6331-11.2012, 22442075
    • Lee KH, Lee JS, Lee D, Seog DH, Lytton J, Ho WK, Lee SH. KIF21A-mediated axonal transport and selective endocytosis underlie the polarized targeting of NCKX2. J Neurosci 2012, 32:4102-4117. 10.1523/JNEUROSCI.6331-11.2012, 22442075.
    • (2012) J Neurosci , vol.32 , pp. 4102-4117
    • Lee, K.H.1    Lee, J.S.2    Lee, D.3    Seog, D.H.4    Lytton, J.5    Ho, W.K.6    Lee, S.H.7
  • 45
    • 33745807269 scopus 로고    scopus 로고
    • Effects of dynactin disruption and dynein depletion on axonal microtubules
    • 10.1111/j.1600-0854.2006.00403.x, 16643276
    • Ahmad FJ, He Y, Myers KA, Hasaka TP, Francis F, Black MM, Baas PW. Effects of dynactin disruption and dynein depletion on axonal microtubules. Traffic 2006, 7:524-537. 10.1111/j.1600-0854.2006.00403.x, 16643276.
    • (2006) Traffic , vol.7 , pp. 524-537
    • Ahmad, F.J.1    He, Y.2    Myers, K.A.3    Hasaka, T.P.4    Francis, F.5    Black, M.M.6    Baas, P.W.7
  • 47
    • 0026606451 scopus 로고
    • Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides
    • 10.1083/jcb.117.3.595, 2289440, 1533397
    • Ferreira A, Niclas J, Vale RD, Banker G, Kosik KS. Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides. J Cell Biol 1992, 117:595-606. 10.1083/jcb.117.3.595, 2289440, 1533397.
    • (1992) J Cell Biol , vol.117 , pp. 595-606
    • Ferreira, A.1    Niclas, J.2    Vale, R.D.3    Banker, G.4    Kosik, K.S.5
  • 48
    • 0037198709 scopus 로고    scopus 로고
    • Dynactin is necessary for synapse stabilization
    • 10.1016/S0896-6273(02)00721-3, 12062020
    • Eaton BA, Fetter RD, Davis GW. Dynactin is necessary for synapse stabilization. Neuron 2002, 34:729-741. 10.1016/S0896-6273(02)00721-3, 12062020.
    • (2002) Neuron , vol.34 , pp. 729-741
    • Eaton, B.A.1    Fetter, R.D.2    Davis, G.W.3
  • 49
    • 0033135885 scopus 로고    scopus 로고
    • Dynein-dynactin function and sensory axon growth during Drosophila metamorphosis: a role for retrograde motors
    • 10.1006/dbio.1999.9217, 10208745
    • Murphey RK, Caruccio PC, Getzinger M, Westgate PJ, Phillis RW. Dynein-dynactin function and sensory axon growth during Drosophila metamorphosis: a role for retrograde motors. Dev Biol 1999, 209:86-97. 10.1006/dbio.1999.9217, 10208745.
    • (1999) Dev Biol , vol.209 , pp. 86-97
    • Murphey, R.K.1    Caruccio, P.C.2    Getzinger, M.3    Westgate, P.J.4    Phillis, R.W.5
  • 50
    • 84883767439 scopus 로고    scopus 로고
    • The Kinesin-3, Unc-104 regulates dendrite morphogenesis and synaptic development in Drosophila
    • doi:10.1534/genetics.1113.151639
    • Kern JV, Zhang YV, Kramer S, Brenman JE, Rasse TM. The Kinesin-3, Unc-104 regulates dendrite morphogenesis and synaptic development in Drosophila. Genetics 2013, doi:10.1534/genetics.1113.151639.
    • (2013) Genetics
    • Kern, J.V.1    Zhang, Y.V.2    Kramer, S.3    Brenman, J.E.4    Rasse, T.M.5
  • 51
    • 34547541598 scopus 로고    scopus 로고
    • A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport
    • 10.1038/nn1936, 17643120
    • Pack-Chung E, Kurshan PT, Dickman DK, Schwarz TL. A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport. Nat Neurosci 2007, 10:980-989. 10.1038/nn1936, 17643120.
    • (2007) Nat Neurosci , vol.10 , pp. 980-989
    • Pack-Chung, E.1    Kurshan, P.T.2    Dickman, D.K.3    Schwarz, T.L.4
  • 52
    • 50349090965 scopus 로고    scopus 로고
    • Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics
    • 10.1152/physrev.00023.2007, 18626067
    • Hirokawa N, Noda Y. Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics. Physiol Rev 2008, 88:1089-1118. 10.1152/physrev.00023.2007, 18626067.
    • (2008) Physiol Rev , vol.88 , pp. 1089-1118
    • Hirokawa, N.1    Noda, Y.2
  • 53
    • 0023618902 scopus 로고
    • Retinal axons with and without their somata, growing to and arborizing in the tectum of Xenopus embryos: a time-lapse video study of single fibers in vivo
    • Harris WA, Holt CE, Bonhoeffer F. Retinal axons with and without their somata, growing to and arborizing in the tectum of Xenopus embryos: a time-lapse video study of single fibers in vivo. Development 1987, 101:123-133.
    • (1987) Development , vol.101 , pp. 123-133
    • Harris, W.A.1    Holt, C.E.2    Bonhoeffer, F.3
  • 54
  • 55
    • 0037015276 scopus 로고    scopus 로고
    • Rapid movement of microtubules in axons
    • 10.1016/S0960-9822(02)01078-3, 12225664
    • Wang L, Brown A. Rapid movement of microtubules in axons. Curr Biol 2002, 12:1496-1501. 10.1016/S0960-9822(02)01078-3, 12225664.
    • (2002) Curr Biol , vol.12 , pp. 1496-1501
    • Wang, L.1    Brown, A.2
  • 56
    • 84863782833 scopus 로고    scopus 로고
    • A novel role for retrograde transport of microtubules in the axon
    • Baas PW, Mozgova OI. A novel role for retrograde transport of microtubules in the axon. Cytoskeleton (Hoboken) 2012, 69:416-425.
    • (2012) Cytoskeleton (Hoboken) , vol.69 , pp. 416-425
    • Baas, P.W.1    Mozgova, O.I.2
  • 57
    • 33646671227 scopus 로고    scopus 로고
    • Microtubule transport in the axon: re-thinking a potential role for the actin cytoskeleton
    • 10.1177/1073858405283428, 16514008
    • Myers KA, He Y, Hasaka TP, Baas PW. Microtubule transport in the axon: re-thinking a potential role for the actin cytoskeleton. Neuroscientist 2006, 12:107-118. 10.1177/1073858405283428, 16514008.
    • (2006) Neuroscientist , vol.12 , pp. 107-118
    • Myers, K.A.1    He, Y.2    Hasaka, T.P.3    Baas, P.W.4
  • 58
    • 33745868372 scopus 로고    scopus 로고
    • Axonal transport of microtubules: the long and short of it
    • 10.1111/j.1600-0854.2006.00392.x, 16643272
    • Baas PW, Vidya NC, Myers KA. Axonal transport of microtubules: the long and short of it. Traffic 2006, 7:490-498. 10.1111/j.1600-0854.2006.00392.x, 16643272.
    • (2006) Traffic , vol.7 , pp. 490-498
    • Baas, P.W.1    Vidya, N.C.2    Myers, K.A.3
  • 59
    • 84860174849 scopus 로고    scopus 로고
    • Microtubule redistribution in growth cones elicited by focal inactivation of kinesin-5
    • 10.1523/JNEUROSCI.0144-12.2012, 3347042, 22539840
    • Nadar VC, Lin S, Baas PW. Microtubule redistribution in growth cones elicited by focal inactivation of kinesin-5. J Neurosci 2012, 32:5783-5794. 10.1523/JNEUROSCI.0144-12.2012, 3347042, 22539840.
    • (2012) J Neurosci , vol.32 , pp. 5783-5794
    • Nadar, V.C.1    Lin, S.2    Baas, P.W.3
  • 60
    • 34548833602 scopus 로고    scopus 로고
    • Kinesin-5 regulates the growth of the axon by acting as a brake on its microtubule array
    • 10.1083/jcb.200702074, 2064629, 17846176
    • Myers KA, Baas PW. Kinesin-5 regulates the growth of the axon by acting as a brake on its microtubule array. J Cell Biol 2007, 178:1081-1091. 10.1083/jcb.200702074, 2064629, 17846176.
    • (2007) J Cell Biol , vol.178 , pp. 1081-1091
    • Myers, K.A.1    Baas, P.W.2
  • 61
    • 84866990769 scopus 로고    scopus 로고
    • Mitotic motors coregulate microtubule patterns in axons and dendrites
    • 10.1523/JNEUROSCI.3070-12.2012, 3482493, 23035110
    • Lin S, Liu M, Mozgova OI, Yu W, Baas PW. Mitotic motors coregulate microtubule patterns in axons and dendrites. J Neurosci 2012, 32:14033-14049. 10.1523/JNEUROSCI.3070-12.2012, 3482493, 23035110.
    • (2012) J Neurosci , vol.32 , pp. 14033-14049
    • Lin, S.1    Liu, M.2    Mozgova, O.I.3    Yu, W.4    Baas, P.W.5
  • 62
    • 78049514886 scopus 로고    scopus 로고
    • Kinesin-12, a mitotic microtubule-associated motor protein, impacts axonal growth, navigation, and branching
    • 10.1523/JNEUROSCI.3739-10.2010, 3064264, 21048148
    • Liu M, Nadar VC, Kozielski F, Kozlowska M, Yu W, Baas PW. Kinesin-12, a mitotic microtubule-associated motor protein, impacts axonal growth, navigation, and branching. J Neurosci 2010, 30:14896-14906. 10.1523/JNEUROSCI.3739-10.2010, 3064264, 21048148.
    • (2010) J Neurosci , vol.30 , pp. 14896-14906
    • Liu, M.1    Nadar, V.C.2    Kozielski, F.3    Kozlowska, M.4    Yu, W.5    Baas, P.W.6
  • 63
    • 34250677626 scopus 로고    scopus 로고
    • Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowth
    • 10.1523/JNEUROSCI.1135-07.2007, 17522326
    • Grabham PW, Seale GE, Bennecib M, Goldberg DJ, Vallee RB. Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowth. J Neurosci 2007, 27:5823-5834. 10.1523/JNEUROSCI.1135-07.2007, 17522326.
    • (2007) J Neurosci , vol.27 , pp. 5823-5834
    • Grabham, P.W.1    Seale, G.E.2    Bennecib, M.3    Goldberg, D.J.4    Vallee, R.B.5
  • 64
    • 33748541597 scopus 로고    scopus 로고
    • Antagonistic forces generated by cytoplasmic dynein and myosin-II during growth cone turning and axonal retraction
    • 10.1111/j.1600-0854.2006.00476.x, 16911591
    • Myers KA, Tint I, Nadar CV, He Y, Black MM, Baas PW. Antagonistic forces generated by cytoplasmic dynein and myosin-II during growth cone turning and axonal retraction. Traffic 2006, 7:1333-1351. 10.1111/j.1600-0854.2006.00476.x, 16911591.
    • (2006) Traffic , vol.7 , pp. 1333-1351
    • Myers, K.A.1    Tint, I.2    Nadar, C.V.3    He, Y.4    Black, M.M.5    Baas, P.W.6
  • 65
    • 34347338618 scopus 로고    scopus 로고
    • A microtubule-based, dynein-dependent force induces local cell protrusions: implications for neurite initiation
    • Dehmelt L, Nalbant P, Steffen W, Halpain S. A microtubule-based, dynein-dependent force induces local cell protrusions: implications for neurite initiation. Brain Cell Biol 2006, 35:39-56.
    • (2006) Brain Cell Biol , vol.35 , pp. 39-56
    • Dehmelt, L.1    Nalbant, P.2    Steffen, W.3    Halpain, S.4
  • 66
    • 84880944148 scopus 로고    scopus 로고
    • Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor
    • 10.1371/journal.pbio.1001611, 3712912, 23874158
    • Lazarus JE, Moughamian AJ, Tokito MK, Holzbaur EL. Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor. PLoS Biol 2013, 11:e1001611. 10.1371/journal.pbio.1001611, 3712912, 23874158.
    • (2013) PLoS Biol , vol.11
    • Lazarus, J.E.1    Moughamian, A.J.2    Tokito, M.K.3    Holzbaur, E.L.4
  • 67
    • 5344253900 scopus 로고    scopus 로고
    • Molecular motors in neuronal development, intracellular transport and diseases
    • 10.1016/j.conb.2004.08.011, 15464889
    • Hirokawa N, Takemura R. Molecular motors in neuronal development, intracellular transport and diseases. Curr Opin Neurobiol 2004, 14:564-573. 10.1016/j.conb.2004.08.011, 15464889.
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 564-573
    • Hirokawa, N.1    Takemura, R.2
  • 68
    • 84878562310 scopus 로고    scopus 로고
    • Initial neurite outgrowth in Drosophila neurons is driven by Kinesin-powered microtubule sliding
    • 10.1016/j.cub.2013.04.050, 23707427
    • Lu W, Fox P, Lakonishok M, Davidson MW, Gelfand VI. Initial neurite outgrowth in Drosophila neurons is driven by Kinesin-powered microtubule sliding. Curr Biol 2013, 23:1018-1023. 10.1016/j.cub.2013.04.050, 23707427.
    • (2013) Curr Biol , vol.23 , pp. 1018-1023
    • Lu, W.1    Fox, P.2    Lakonishok, M.3    Davidson, M.W.4    Gelfand, V.I.5
  • 69
    • 77955438584 scopus 로고    scopus 로고
    • Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape
    • 10.1073/pnas.1004736107, 2901438, 20566873
    • Jolly AL, Kim H, Srinivasan D, Lakonishok M, Larson AG, Gelfand VI. Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape. Proc Natl Acad Sci U S A 2010, 107:12151-12156. 10.1073/pnas.1004736107, 2901438, 20566873.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 12151-12156
    • Jolly, A.L.1    Kim, H.2    Srinivasan, D.3    Lakonishok, M.4    Larson, A.G.5    Gelfand, V.I.6
  • 70
    • 33644870579 scopus 로고    scopus 로고
    • A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon
    • 10.1016/j.neuron.2006.02.005, 16543128
    • Jacobson C, Schnapp B, Banker GA. A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon. Neuron 2006, 49:797-804. 10.1016/j.neuron.2006.02.005, 16543128.
    • (2006) Neuron , vol.49 , pp. 797-804
    • Jacobson, C.1    Schnapp, B.2    Banker, G.A.3
  • 71
    • 84878918174 scopus 로고    scopus 로고
    • Mitochondrial trafficking in neurons
    • 10.1101/cshperspect.a011304, 23732472
    • Schwarz TL. Mitochondrial trafficking in neurons. Cold Spring Harb Perspect Biol 2013, 5:a011304. 10.1101/cshperspect.a011304, 23732472.
    • (2013) Cold Spring Harb Perspect Biol , vol.5
    • Schwarz, T.L.1
  • 73
    • 34548547281 scopus 로고    scopus 로고
    • Mitochondrial degeneration in dystrophic neurites of senile plaques may lead to extracellular deposition of fine filaments
    • 10.1007/s00429-007-0153-1, 17717688
    • Fiala JC, Feinberg M, Peters A, Barbas H. Mitochondrial degeneration in dystrophic neurites of senile plaques may lead to extracellular deposition of fine filaments. Brain Struct Funct 2007, 212:195-207. 10.1007/s00429-007-0153-1, 17717688.
    • (2007) Brain Struct Funct , vol.212 , pp. 195-207
    • Fiala, J.C.1    Feinberg, M.2    Peters, A.3    Barbas, H.4
  • 74
    • 62249115658 scopus 로고    scopus 로고
    • A macroscopic model of traffic jams in axons
    • 10.1016/j.mbs.2009.01.005, 19563741
    • Kuznetsov AV, Avramenko AA. A macroscopic model of traffic jams in axons. Math Biosci 2009, 218:142-152. 10.1016/j.mbs.2009.01.005, 19563741.
    • (2009) Math Biosci , vol.218 , pp. 142-152
    • Kuznetsov, A.V.1    Avramenko, A.A.2
  • 75
    • 67449132352 scopus 로고    scopus 로고
    • Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients
    • 10.1111/j.1471-4159.2009.06104.x, 19453301
    • Kasher PR, De Vos KJ, Wharton SB, Manser C, Bennett EJ, Bingley M, Wood JD, Milner R, McDermott CJ, Miller CC, et al. Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients. J Neurochem 2009, 110:34-44. 10.1111/j.1471-4159.2009.06104.x, 19453301.
    • (2009) J Neurochem , vol.110 , pp. 34-44
    • Kasher, P.R.1    De Vos, K.J.2    Wharton, S.B.3    Manser, C.4    Bennett, E.J.5    Bingley, M.6    Wood, J.D.7    Milner, R.8    McDermott, C.J.9    Miller, C.C.10
  • 76
    • 33845353014 scopus 로고    scopus 로고
    • A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition
    • 10.1093/hmg/ddl431, 17101632
    • Tarrade A, Fassier C, Courageot S, Charvin D, Vitte J, Peris L, Thorel A, Mouisel E, Fonknechten N, Roblot N, et al. A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition. Hum Mol Genet 2006, 15:3544-3558. 10.1093/hmg/ddl431, 17101632.
    • (2006) Hum Mol Genet , vol.15 , pp. 3544-3558
    • Tarrade, A.1    Fassier, C.2    Courageot, S.3    Charvin, D.4    Vitte, J.5    Peris, L.6    Thorel, A.7    Mouisel, E.8    Fonknechten, N.9    Roblot, N.10
  • 77
    • 68749088676 scopus 로고    scopus 로고
    • Dendrites differ from axons in patterns of microtubule stability and polymerization during development
    • 10.1186/1749-8104-4-26, 2717962, 19602271
    • Kollins KM, Bell RL, Butts M, Withers GS. Dendrites differ from axons in patterns of microtubule stability and polymerization during development. Neural Dev 2009, 4:26. 10.1186/1749-8104-4-26, 2717962, 19602271.
    • (2009) Neural Dev , vol.4 , pp. 26
    • Kollins, K.M.1    Bell, R.L.2    Butts, M.3    Withers, G.S.4
  • 78
    • 79953121016 scopus 로고    scopus 로고
    • IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia
    • 10.1093/hmg/ddr036, 21273291
    • Cheishvili D, Maayan C, Cohen-Kupiec R, Lefler S, Weil M, Ast G, Razin A. IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia. Hum Mol Genet 2011, 20:1585-1594. 10.1093/hmg/ddr036, 21273291.
    • (2011) Hum Mol Genet , vol.20 , pp. 1585-1594
    • Cheishvili, D.1    Maayan, C.2    Cohen-Kupiec, R.3    Lefler, S.4    Weil, M.5    Ast, G.6    Razin, A.7
  • 79
    • 84879477553 scopus 로고    scopus 로고
    • The microtubule regulatory protein Stathmin is required to maintain the integrity of axonal microtubules in Drosophila
    • 10.1371/journal.pone.0068324, 3694009, 23840848
    • Duncan JE, Lytle NK, Zuniga A, Goldstein LS. The microtubule regulatory protein Stathmin is required to maintain the integrity of axonal microtubules in Drosophila. PLoS One 2013, 8:e68324. 10.1371/journal.pone.0068324, 3694009, 23840848.
    • (2013) PLoS One , vol.8
    • Duncan, J.E.1    Lytle, N.K.2    Zuniga, A.3    Goldstein, L.S.4
  • 80
    • 77952538901 scopus 로고    scopus 로고
    • Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy
    • 10.1093/hmg/ddq058, 20176735
    • Wen HL, Lin YT, Ting CH, Lin-Chao S, Li H, Hsieh-Li HM. Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy. Hum Mol Genet 2010, 19:1766-1778. 10.1093/hmg/ddq058, 20176735.
    • (2010) Hum Mol Genet , vol.19 , pp. 1766-1778
    • Wen, H.L.1    Lin, Y.T.2    Ting, C.H.3    Lin-Chao, S.4    Li, H.5    Hsieh-Li, H.M.6
  • 81
    • 0036171404 scopus 로고    scopus 로고
    • Stathmin-deficient mice develop an age-dependent axonopathy of the central and peripheral nervous systems
    • 10.1016/S0002-9440(10)64866-3, 1850667, 11839567
    • Liedtke W, Leman EE, Fyffe RE, Raine CS, Schubart UK. Stathmin-deficient mice develop an age-dependent axonopathy of the central and peripheral nervous systems. Am J Pathol 2002, 160:469-480. 10.1016/S0002-9440(10)64866-3, 1850667, 11839567.
    • (2002) Am J Pathol , vol.160 , pp. 469-480
    • Liedtke, W.1    Leman, E.E.2    Fyffe, R.E.3    Raine, C.S.4    Schubart, U.K.5
  • 82
    • 0037175395 scopus 로고    scopus 로고
    • Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motor neuron disease
    • 10.1083/jcb.200208001, 2173089, 12446740
    • Bommel H, Xie G, Rossoll W, Wiese S, Jablonka S, Boehm T, Sendtner M. Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motor neuron disease. J Cell Biol 2002, 159:563-569. 10.1083/jcb.200208001, 2173089, 12446740.
    • (2002) J Cell Biol , vol.159 , pp. 563-569
    • Bommel, H.1    Xie, G.2    Rossoll, W.3    Wiese, S.4    Jablonka, S.5    Boehm, T.6    Sendtner, M.7
  • 83
    • 0036842251 scopus 로고    scopus 로고
    • A missense mutation in Tbce causes progressive motor neuronopathy in mice
    • 10.1038/ng1016, 12389029
    • Martin N, Jaubert J, Gounon P, Salido E, Haase G, Szatanik M, Guenet JL. A missense mutation in Tbce causes progressive motor neuronopathy in mice. Nat Genet 2002, 32:443-447. 10.1038/ng1016, 12389029.
    • (2002) Nat Genet , vol.32 , pp. 443-447
    • Martin, N.1    Jaubert, J.2    Gounon, P.3    Salido, E.4    Haase, G.5    Szatanik, M.6    Guenet, J.L.7
  • 84
    • 84863452328 scopus 로고    scopus 로고
    • Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins)
    • 10.1523/JNEUROSCI.0416-12.2012, 3666083, 22764224
    • Alves-Silva J, Sánchez-Soriano N, Beaven R, Klein M, Parkin J, Millard T, Bellen H, Venken KJT, Ballestrem C, Kammerer RA, Prokop A. Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins). J Neurosci 2012, 32:9143-9158. 10.1523/JNEUROSCI.0416-12.2012, 3666083, 22764224.
    • (2012) J Neurosci , vol.32 , pp. 9143-9158
    • Alves-Silva, J.1    Sánchez-Soriano, N.2    Beaven, R.3    Klein, M.4    Parkin, J.5    Millard, T.6    Bellen, H.7    Venken, K.J.T.8    Ballestrem, C.9    Kammerer, R.A.10    Prokop, A.11
  • 85
    • 69649101282 scopus 로고    scopus 로고
    • Mouse ACF7 and Drosophila Short stop modulate filopodia formation and microtubule organization during neuronal growth
    • 10.1242/jcs.046268, 2704885, 19571116
    • Sánchez-Soriano N, Travis M, Dajas-Bailador F, Goncalves-Pimentel C, Whitmarsh AJ, Prokop A. Mouse ACF7 and Drosophila Short stop modulate filopodia formation and microtubule organization during neuronal growth. J Cell Sci 2009, 122:2534-2542. 10.1242/jcs.046268, 2704885, 19571116.
    • (2009) J Cell Sci , vol.122 , pp. 2534-2542
    • Sánchez-Soriano, N.1    Travis, M.2    Dajas-Bailador, F.3    Goncalves-Pimentel, C.4    Whitmarsh, A.J.5    Prokop, A.6
  • 86
    • 84860129343 scopus 로고    scopus 로고
    • Hereditary sensory autonomic neuropathy caused by a mutation in dystonin
    • 10.1002/ana.23524, 22522446
    • Edvardson S, Cinnamon Y, Jalas C, Shaag A, Maayan C, Axelrod FB, Elpeleg O. Hereditary sensory autonomic neuropathy caused by a mutation in dystonin. Ann Neurol 2012, 71:569-572. 10.1002/ana.23524, 22522446.
    • (2012) Ann Neurol , vol.71 , pp. 569-572
    • Edvardson, S.1    Cinnamon, Y.2    Jalas, C.3    Shaag, A.4    Maayan, C.5    Axelrod, F.B.6    Elpeleg, O.7
  • 87
    • 79751469568 scopus 로고    scopus 로고
    • Inhibition of Kinesin-5, a microtubule-based motor protein, as a strategy for enhancing regeneration of adult axons
    • 10.1111/j.1600-0854.2010.01152.x, 3037443, 21166743
    • Lin S, Liu M, Son YJ, Himes TB, Snow DM, Yu W, Baas PW. Inhibition of Kinesin-5, a microtubule-based motor protein, as a strategy for enhancing regeneration of adult axons. Traffic 2011, 12:269-286. 10.1111/j.1600-0854.2010.01152.x, 3037443, 21166743.
    • (2011) Traffic , vol.12 , pp. 269-286
    • Lin, S.1    Liu, M.2    Son, Y.J.3    Himes, T.B.4    Snow, D.M.5    Yu, W.6    Baas, P.W.7
  • 88
    • 53349164540 scopus 로고    scopus 로고
    • Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons
    • 10.1038/ncb1777, 2588425, 18758451
    • Zheng Y, Wildonger J, Ye B, Zhang Y, Kita A, Younger SH, Zimmerman S, Jan LY, Jan YN. Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat Cell Biol 2008, 10:1172-1180. 10.1038/ncb1777, 2588425, 18758451.
    • (2008) Nat Cell Biol , vol.10 , pp. 1172-1180
    • Zheng, Y.1    Wildonger, J.2    Ye, B.3    Zhang, Y.4    Kita, A.5    Younger, S.H.6    Zimmerman, S.7    Jan, L.Y.8    Jan, Y.N.9
  • 89
    • 77953812408 scopus 로고    scopus 로고
    • 100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future
    • 10.1038/nrn2839, 20383202
    • Bellen HJ, Tong C, Tsuda H. 100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future. Nat Rev Neurosci 2010, 11:514-522. 10.1038/nrn2839, 20383202.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 514-522
    • Bellen, H.J.1    Tong, C.2    Tsuda, H.3
  • 90
    • 84860487324 scopus 로고    scopus 로고
    • Analysis of adhesion molecules and basement membrane contributions to synaptic adhesion at the Drosophila embryonic NMJ
    • 10.1371/journal.pone.0036339, 3340374, 22558441
    • Koper A, Schenck A, Prokop A. Analysis of adhesion molecules and basement membrane contributions to synaptic adhesion at the Drosophila embryonic NMJ. PLoS One 2012, 7:e36339. 10.1371/journal.pone.0036339, 3340374, 22558441.
    • (2012) PLoS One , vol.7
    • Koper, A.1    Schenck, A.2    Prokop, A.3
  • 91
    • 79953156213 scopus 로고    scopus 로고
    • Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model
    • 10.1371/journal.pone.0018340, 3065487, 21464901
    • Gonçalves-Pimentel C, Gombos R, Mihály J, Sánchez-Soriano N, Prokop A. Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model. PLoS ONE 2011, 6:e18340. 10.1371/journal.pone.0018340, 3065487, 21464901.
    • (2011) PLoS ONE , vol.6
    • Gonçalves-Pimentel, C.1    Gombos, R.2    Mihály, J.3    Sánchez-Soriano, N.4    Prokop, A.5
  • 93
    • 84870192151 scopus 로고    scopus 로고
    • Axon degeneration and regeneration: insights from Drosophila models of nerve injury
    • 10.1146/annurev-cellbio-101011-155836, 22831639
    • Fang Y, Bonini NM. Axon degeneration and regeneration: insights from Drosophila models of nerve injury. Annu Rev Cell Dev Biol 2012, 28:575-597. 10.1146/annurev-cellbio-101011-155836, 22831639.
    • (2012) Annu Rev Cell Dev Biol , vol.28 , pp. 575-597
    • Fang, Y.1    Bonini, N.M.2
  • 94
    • 84870159570 scopus 로고    scopus 로고
    • Probing mechanisms that underlie human neurodegenerative disease in Drosophila
    • 10.1146/annurev-genet-110711-155456, 3663445, 22974305
    • Jaiswal M, Sandoval H, Zhang K, Bayat V, Bellen HJ. Probing mechanisms that underlie human neurodegenerative disease in Drosophila. Annu Rev Genet 2012, 46:371-396. 10.1146/annurev-genet-110711-155456, 3663445, 22974305.
    • (2012) Annu Rev Genet , vol.46 , pp. 371-396
    • Jaiswal, M.1    Sandoval, H.2    Zhang, K.3    Bayat, V.4    Bellen, H.J.5
  • 95
    • 84858823493 scopus 로고    scopus 로고
    • Modeling active transport in Drosophila unipolar motor neurons
    • 10.1080/10255842.2010.515983, 21337219
    • Kuznetsov AV. Modeling active transport in Drosophila unipolar motor neurons. Comput Methods Biomech Biomed Engin 2011, 14:1117-1131. 10.1080/10255842.2010.515983, 21337219.
    • (2011) Comput Methods Biomech Biomed Engin , vol.14 , pp. 1117-1131
    • Kuznetsov, A.V.1
  • 96
    • 77956064208 scopus 로고    scopus 로고
    • Method of modeling intracellular transport in branching neurites: application to axons and dendrites of Drosophila sensory neurons
    • 10.1080/10255841003664727, 20419522
    • Kuznetsov AV. Method of modeling intracellular transport in branching neurites: application to axons and dendrites of Drosophila sensory neurons. Comput Methods Biomech Biomed Engin 2011, 14:239-251. 10.1080/10255841003664727, 20419522.
    • (2011) Comput Methods Biomech Biomed Engin , vol.14 , pp. 239-251
    • Kuznetsov, A.V.1
  • 97
    • 84866284504 scopus 로고    scopus 로고
    • Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins
    • 10.1016/j.molcel.2012.06.025, 3549492, 22857951
    • Liu JS, Schubert CR, Fu X, Fourniol FJ, Jaiswal JK, Houdusse A, Stultz CM, Moores CA, Walsh CA. Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins. Mol Cell 2012, 47:707-721. 10.1016/j.molcel.2012.06.025, 3549492, 22857951.
    • (2012) Mol Cell , vol.47 , pp. 707-721
    • Liu, J.S.1    Schubert, C.R.2    Fu, X.3    Fourniol, F.J.4    Jaiswal, J.K.5    Houdusse, A.6    Stultz, C.M.7    Moores, C.A.8    Walsh, C.A.9
  • 98
    • 14844331501 scopus 로고    scopus 로고
    • Molecular motors and mechanisms of directional transport in neurons
    • 10.1038/nrn1624, 15711600
    • Hirokawa N, Takemura R. Molecular motors and mechanisms of directional transport in neurons. Nat Rev Neurosci 2005, 6:201-214. 10.1038/nrn1624, 15711600.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 201-214
    • Hirokawa, N.1    Takemura, R.2
  • 99
    • 0033693656 scopus 로고    scopus 로고
    • A kinesin family tree
    • Kim AJ, Endow SA. A kinesin family tree. J Cell Sci 2000, 113(Pt 21):3681-3682.
    • (2000) J Cell Sci , vol.113 , Issue.PART 21 , pp. 3681-3682
    • Kim, A.J.1    Endow, S.A.2
  • 100
    • 84865729967 scopus 로고    scopus 로고
    • The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A
    • 10.1016/j.str.2012.07.002, 22863567
    • Huo L, Yue Y, Ren J, Yu J, Liu J, Yu Y, Ye F, Xu T, Zhang M, Feng W. The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A. Structure 2012, 20:1550-1561. 10.1016/j.str.2012.07.002, 22863567.
    • (2012) Structure , vol.20 , pp. 1550-1561
    • Huo, L.1    Yue, Y.2    Ren, J.3    Yu, J.4    Liu, J.5    Yu, Y.6    Ye, F.7    Xu, T.8    Zhang, M.9    Feng, W.10
  • 102
    • 84860332776 scopus 로고    scopus 로고
    • FlyBase 101 - the basics of navigating FlyBase
    • 10.1093/nar/gkr1030, 3245098, 22127867
    • McQuilton P, St Pierre SE, Thurmond J. FlyBase 101 - the basics of navigating FlyBase. Nucleic Acids Res 2012, 40:D706-D714. 10.1093/nar/gkr1030, 3245098, 22127867.
    • (2012) Nucleic Acids Res , vol.40
    • McQuilton, P.1    St Pierre, S.E.2    Thurmond, J.3
  • 103
    • 0033562664 scopus 로고    scopus 로고
    • Commissure formation in the embryonic CNS of Drosophila. I. Identification of the required gene functions
    • 10.1006/dbio.1999.9235, 10328928
    • Hummel T, Schimmelpfeng K, Klambt C. Commissure formation in the embryonic CNS of Drosophila. I. Identification of the required gene functions. Dev Biol 1999, 209:381-398. 10.1006/dbio.1999.9235, 10328928.
    • (1999) Dev Biol , vol.209 , pp. 381-398
    • Hummel, T.1    Schimmelpfeng, K.2    Klambt, C.3
  • 104
    • 0038107541 scopus 로고    scopus 로고
    • Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1
    • 10.1091/mbc.E03-01-0049, 165665, 12857853
    • Eckley DM, Schroer TA. Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. Mol Biol Cell 2003, 14:2645-2654. 10.1091/mbc.E03-01-0049, 165665, 12857853.
    • (2003) Mol Biol Cell , vol.14 , pp. 2645-2654
    • Eckley, D.M.1    Schroer, T.A.2
  • 105
    • 84880014019 scopus 로고    scopus 로고
    • Microtubule-based transport - basic mechanisms, traffic rules and role in neurological pathogenesis
    • 10.1242/jcs.115030, 23729742
    • Franker MA, Hoogenraad CC. Microtubule-based transport - basic mechanisms, traffic rules and role in neurological pathogenesis. J Cell Sci 2013, 126:2319-2329. 10.1242/jcs.115030, 23729742.
    • (2013) J Cell Sci , vol.126 , pp. 2319-2329
    • Franker, M.A.1    Hoogenraad, C.C.2
  • 106
    • 84879274077 scopus 로고    scopus 로고
    • The balance between capture and dissociation of presynaptic proteins controls the spatial distribution of synapses
    • 10.1016/j.neuron.2013.04.035, 23727120
    • Wu YE, Huo L, Maeder CI, Feng W, Shen K. The balance between capture and dissociation of presynaptic proteins controls the spatial distribution of synapses. Neuron 2013, 78:994-1011. 10.1016/j.neuron.2013.04.035, 23727120.
    • (2013) Neuron , vol.78 , pp. 994-1011
    • Wu, Y.E.1    Huo, L.2    Maeder, C.I.3    Feng, W.4    Shen, K.5
  • 107
    • 84881189138 scopus 로고    scopus 로고
    • JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors
    • 10.1083/jcb.201302078, 23897889
    • Fu MM, Holzbaur EL. JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors. J Cell Biol 2013, 202:495-508. 10.1083/jcb.201302078, 23897889.
    • (2013) J Cell Biol , vol.202 , pp. 495-508
    • Fu, M.M.1    Holzbaur, E.L.2
  • 108
    • 84872796017 scopus 로고    scopus 로고
    • Actin, Spectrin, and associated proteins form a periodic cytoskeletal structure in axons
    • 10.1126/science.1232251, 23239625
    • Xu K, Zhong G, Zhuang X. Actin, Spectrin, and associated proteins form a periodic cytoskeletal structure in axons. Science 2013, 339:452-456. 10.1126/science.1232251, 23239625.
    • (2013) Science , vol.339 , pp. 452-456
    • Xu, K.1    Zhong, G.2    Zhuang, X.3
  • 109
    • 84872506411 scopus 로고    scopus 로고
    • Molecular adaptations allow dynein to generate large collective forces inside cells
    • 10.1016/j.cell.2012.11.044, 23332753
    • Rai AK, Rai A, Ramaiya AJ, Jha R, Mallik R. Molecular adaptations allow dynein to generate large collective forces inside cells. Cell 2013, 152:172-182. 10.1016/j.cell.2012.11.044, 23332753.
    • (2013) Cell , vol.152 , pp. 172-182
    • Rai, A.K.1    Rai, A.2    Ramaiya, A.J.3    Jha, R.4    Mallik, R.5
  • 110
    • 0032741064 scopus 로고    scopus 로고
    • Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport
    • 10.1091/mbc.10.11.3717, 25669, 10564267
    • Martin M, Iyadurai SJ, Gassman A, Gindhart JG, Hays TS, Saxton WM. Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. Mol Biol Cell 1999, 10:3717-3728. 10.1091/mbc.10.11.3717, 25669, 10564267.
    • (1999) Mol Biol Cell , vol.10 , pp. 3717-3728
    • Martin, M.1    Iyadurai, S.J.2    Gassman, A.3    Gindhart, J.G.4    Hays, T.S.5    Saxton, W.M.6
  • 111
    • 79951774017 scopus 로고    scopus 로고
    • KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons
    • 10.1016/j.neulet.2011.01.018, 21256924
    • Lo KY, Kuzmin A, Unger SM, Petersen JD, Silverman MA. KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons. Neurosci Lett 2011, 491:168-173. 10.1016/j.neulet.2011.01.018, 21256924.
    • (2011) Neurosci Lett , vol.491 , pp. 168-173
    • Lo, K.Y.1    Kuzmin, A.2    Unger, S.M.3    Petersen, J.D.4    Silverman, M.A.5
  • 112
    • 84870840958 scopus 로고    scopus 로고
    • A novel role for doublecortin and doublecortin-like kinase in regulating growth cone microtubules
    • 10.1093/hmg/dds395, 23001563
    • Jean DC, Baas PW, Black MM. A novel role for doublecortin and doublecortin-like kinase in regulating growth cone microtubules. Hum Mol Genet 2012, 21:5511-5527. 10.1093/hmg/dds395, 23001563.
    • (2012) Hum Mol Genet , vol.21 , pp. 5511-5527
    • Jean, D.C.1    Baas, P.W.2    Black, M.M.3
  • 113
    • 57149121236 scopus 로고    scopus 로고
    • Drosophila Ensconsin promotes productive recruitment of Kinesin-1 to microtubules
    • 10.1016/j.devcel.2008.10.006, 19081075
    • Sung HH, Telley IA, Papadaki P, Ephrussi A, Surrey T, Rørth P. Drosophila Ensconsin promotes productive recruitment of Kinesin-1 to microtubules. Dev Cell 2008, 15:866-876. 10.1016/j.devcel.2008.10.006, 19081075.
    • (2008) Dev Cell , vol.15 , pp. 866-876
    • Sung, H.H.1    Telley, I.A.2    Papadaki, P.3    Ephrussi, A.4    Surrey, T.5    Rørth, P.6
  • 114
    • 84859465143 scopus 로고    scopus 로고
    • MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function
    • 10.1038/nature10914, 3321085, 22425998
    • Metzger T, Gache V, Xu M, Cadot B, Folker ES, Richardson BE, Gomes ER, Baylies MK. MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function. Nature 2012, 484:120-124. 10.1038/nature10914, 3321085, 22425998.
    • (2012) Nature , vol.484 , pp. 120-124
    • Metzger, T.1    Gache, V.2    Xu, M.3    Cadot, B.4    Folker, E.S.5    Richardson, B.E.6    Gomes, E.R.7    Baylies, M.K.8
  • 115
    • 0032476645 scopus 로고    scopus 로고
    • Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
    • 10.1083/jcb.143.3.777, 2148132, 9813097
    • Ebneth A, Godemann R, Stamer K, Illenberger S, Trinczek B, Mandelkow E. Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease. J Cell Biol 1998, 143:777-794. 10.1083/jcb.143.3.777, 2148132, 9813097.
    • (1998) J Cell Biol , vol.143 , pp. 777-794
    • Ebneth, A.1    Godemann, R.2    Stamer, K.3    Illenberger, S.4    Trinczek, B.5    Mandelkow, E.6
  • 116
    • 83355163345 scopus 로고    scopus 로고
    • The nucleotide-binding state of microtubules modulates kinesin processivity and the ability of Tau to inhibit kinesin-mediated transport
    • 10.1074/jbc.M111.292987, 3234877, 22039058
    • McVicker DP, Chrin LR, Berger CL. The nucleotide-binding state of microtubules modulates kinesin processivity and the ability of Tau to inhibit kinesin-mediated transport. J Biol Chem 2011, 286:42873-42880. 10.1074/jbc.M111.292987, 3234877, 22039058.
    • (2011) J Biol Chem , vol.286 , pp. 42873-42880
    • McVicker, D.P.1    Chrin, L.R.2    Berger, C.L.3
  • 117
    • 62849088641 scopus 로고    scopus 로고
    • The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity
    • 10.1002/jnr.21850, 2739042, 18798283
    • LaPointe NE, Morfini G, Pigino G, Gaisina IN, Kozikowski AP, Binder LI, Brady ST. The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity. J Neurosci Res 2009, 87:440-451. 10.1002/jnr.21850, 2739042, 18798283.
    • (2009) J Neurosci Res , vol.87 , pp. 440-451
    • LaPointe, N.E.1    Morfini, G.2    Pigino, G.3    Gaisina, I.N.4    Kozikowski, A.P.5    Binder, L.I.6    Brady, S.T.7
  • 118
    • 77958459087 scopus 로고    scopus 로고
    • Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies
    • 10.1093/hmg/ddq363, 2957317, 20817925
    • Falzone TL, Gunawardena S, McCleary D, Reis GF, Goldstein LS. Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet 2010, 19:4399-4408. 10.1093/hmg/ddq363, 2957317, 20817925.
    • (2010) Hum Mol Genet , vol.19 , pp. 4399-4408
    • Falzone, T.L.1    Gunawardena, S.2    McCleary, D.3    Reis, G.F.4    Goldstein, L.S.5
  • 119
    • 84880003958 scopus 로고    scopus 로고
    • How to design a genetic mating scheme: a basic training package for Drosophila genetics
    • Roote J, Prokop A. How to design a genetic mating scheme: a basic training package for Drosophila genetics. G3 (Bethesda) 2013, 3:353-358.
    • (2013) G3 (Bethesda) , vol.3 , pp. 353-358
    • Roote, J.1    Prokop, A.2
  • 122
    • 84867547076 scopus 로고    scopus 로고
    • Using primary neuron cultures of Drosophila to analyze neuronal circuit formation and function
    • New York: Humana Press, Hassan BA, Walz W (Series Editor): Neuromethods)
    • Prokop A, Küppers-Munther B, Sánchez-Soriano N. Using primary neuron cultures of Drosophila to analyze neuronal circuit formation and function. The Making and Un-making of Neuronal Circuits in Drosophila. Volume 69 2012, 225-247. New York: Humana Press, Hassan BA, Walz W (Series Editor): Neuromethods).
    • (2012) The Making and Un-making of Neuronal Circuits in Drosophila. Volume 69 , pp. 225-247
    • Prokop, A.1    Küppers-Munther, B.2    Sánchez-Soriano, N.3


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