Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation

Molecular Biology of the Cell

Volumn 22, Issue 10, 2011, Pages 1677-1685

  Capaldo, Christopher T ^a   Koch, Stefan ^a   Kwon, Michael ^a   Laur, Oskar ^b   Parkos, Charles A ^a   Nusrat, Asma ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; MEMBRANE PROTEIN; PROTEIN ZONULA OCCLUDENS 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL MEMBRANE; CELL PROLIFERATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; MITOSIS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL FRACTIONATION; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; COLON; CYCLIN D1; HUMANS; INTESTINAL MUCOSA; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MITOSIS; PDZ DOMAINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STABILITY; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; TIGHT JUNCTIONS;

EID: 79955973354     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-08-0677     Document Type: Article

References (42)

1. Adachi M, Inoko A, Hata M, Furuse K, Umeda K, Itoh M, Tsukita S (2006). Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein. Mol Cell Biol 26, 9003-9015. (Pubitemid 44851957)
2. Balda MS, Garrett MD, Matter K (2003). The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. J Cell Biol 160, 423-432. (Pubitemid 36182732)
3. Balda MS, Matter K (2009). Tight junctions and the regulation of gene expression. Biochim Biophys Acta 1788, 761-767.
4. Beatch M, Jesaitis LA, Gallin WJ, Goodenough DA, Stevenson BR (1996). The tight junction protein ZO-2 contains three PDZ (PSD-95/Discs-Large/ZO-1) domains and an alternatively spliced region. J Biol Chem 271, 25723-25726. (Pubitemid 26347394)
5. Betanzos A, Huerta M, Lopez-Bayghen E, Azuara E, Amerena J, Gonzalez-Mariscal L (2004). The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells. Exp Cell Res 292, 51-66. (Pubitemid 38058263)
6. Diehl JA, Cheng M, Roussel MF, Sherr CJ (1998). Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 12, 3499-3511. (Pubitemid 28553242)
7. Diehl JA, Sherr CJ (1997). A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase. Mol Cell Biol 17, 7362-7374. (Pubitemid 27505965)
8. Diehl JA, Zindy F, Sherr CJ (1997). Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitinproteasome pathway. Genes Dev 11, 957-972. (Pubitemid 27199876)
9. Fu M, Wang C, Li Z, Sakamaki T, Pestell RG (2004). Minireview: cyclin D1: normal and abnormal functions. Endocrinology 145, 5439-5447. (Pubitemid 39564581)
10. Fukami-Kobayashi J, Mitsui Y (1999). Cyclin D1 inhibits cell proliferation through binding to PCNA and cdk2. Exp Cell Res 246, 338-347. (Pubitemid 29393996)
11. Giallourakis C, Cao Z, Green T, Wachtel H, Xie X, Lopez-Illasaca M, Daly M, Rioux J, Xavier R (2006). A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands. Genome Res 16, 1056-1072. (Pubitemid 44162265)
12. Gladden AB, Diehl JA (2005). Location, location, location: the role of cyclin D1 nuclear localization in cancer. J Cell Biochem 96, 906-913. (Pubitemid 41688717)
13. Gonzalez-Mariscal L, Betanzos A, Avila-Flores A (2000). MAGUK proteins: structure and role in the tight junction. Semin Cell Dev Biol 11, 315-324. (Pubitemid 32066139)
14. Gottardi CJ, Arpin M, Fanning AS, Louvard D (1996). The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts. Proc Natl Acad Sci USA 93, 10779-10784. (Pubitemid 26333066)
15. Guillemot L, Paschoud S, Pulimeno P, Foglia A, Citi S (2008). The cytoplasmic plaque of tight junctions: a scaffolding and signalling center. Biochim Biophys Acta 1778, 601-613. (Pubitemid 351317804)
16. Guo Y, Yang K, Harwalkar J, Nye JM, Mason DR, Garrett MD, Hitomi M, Stacey DW (2005). Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis. Oncogene 24, 2599-2612. (Pubitemid 40593088)
17. Harris BZ, Lim WA (2001). Mechanism and role of PDZ domains in signaling complex assembly. J Cell Sci 114, 3219-3231. (Pubitemid 32998900)
18. Haskins J, Gu L, Wittchen ES, Hibbard J, Stevenson BR (1998). ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol 141, 199-208. (Pubitemid 28182652)
19. Hitomi M, Yang K, Stacey AW, Stacey DW (2008). Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression. Mol Cell Biol 28, 5478-5493.
20. Huerta M, Munoz R, Tapia R, Soto-Reyes E, Ramirez L, Recillas-Targa F, Gonzalez-Mariscal L, Lopez-Bayghen E (2007). Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc. Mol Biol Cell 18, 4826-4836. (Pubitemid 350246685)
21. Inoko A, Itoh M, Tamura A, Matsuda M, Furuse M, Tsukita S (2003). Expression and distribution of ZO-3, a tight junction MAGUK protein, in mouse tissues. Genes Cells 8, 837-845. (Pubitemid 37428013)
22. Islas S, Vega J, Ponce L, Gonzalez-Mariscal L (2002). Nuclear localization of the tight junction protein ZO-2 in epithelial cells. Exp Cell Res 274, 138-148.
23. Jaramillo BE, Ponce A, Moreno J, Betanzos A, Huerta M, Lopez-Bayghen E, Gonzalez-Mariscal L (2004). Characterization of the tight junction protein ZO-2 localized at the nucleus of epithelial cells. Exp Cell Res 297, 247-258. (Pubitemid 38759577)
24. Kaoutzani P, Parkos CA, Delp-Archer C, Madara JL (1993). Isolation of plasma membrane fractions from the intestinal epithelial model T84. Am J Physiol 264, C1327-C1335. (Pubitemid 23158841)
25. Kiener TK, Selptsova-Friedrich I, Hunziker W (2008). Tjp3/zo-3 is critical for epidermal barrier function in zebrafish embryos. Dev Biol 316, 36-49.
26. Kwak YT, Li R, Becerra CR, Tripathy D, Frenkel EP, Verma UN (2005). IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation. J Biol Chem 280, 33945-33952. (Pubitemid 41443114)
27. Malumbres M, Barbacid M (2001). To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 1, 222-231. (Pubitemid 33741897)
28. Mandell KJ, Babbin BA, Nusrat A, Parkos CA (2005). Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on beta1 integrins and Rap1 activity. J Biol Chem 280, 11665-11674. (Pubitemid 40418481)
29. Matter K, Balda MS (2007). Epithelial tight junctions, gene expression and nucleo-junctional interplay. J Cell Sci 120, 1505-1511. (Pubitemid 46831780)
30. Nava P et al. (2010). Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways. Immunity 32, 392-402.
31. Pagano M, Theodoras AM, Tam SW, Draetta GF (1994). Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes Dev 8, 1627-1639. (Pubitemid 24236242)
32. Paris L, Tonutti L, Vannini C, Bazzoni G (2008). Structural organization of the tight junctions. Biochim Biophys Acta 1778, 646-659. (Pubitemid 351317797)
33. Severson EA, Lee WY, Capaldo CT, Nusrat A, Parkos CA (2009). Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration. Mol Biol Cell 20, 1916-1925.
34. Sherr CJ (1995). D-type cyclins. Trends Biochem Sci 20, 187-190.
35. Sherr CJ, Roberts JM (2004). Living with or without cyclins and cyclin-dependent kinases. Genes Dev 18, 2699-2711. (Pubitemid 39507762)
36. Solomon DA, Wang Y, Fox SR, Lambeck TC, Giesting S, Lan Z, Senderowicz AM, Conti CJ, Knudsen ES (2003). Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation. J Biol Chem 278, 30339-30347. (Pubitemid 36962428)
37. Sourisseau T, Georgiadis A, Tsapara A, Ali RR, Pestell R, Matter K, Balda MS (2006). Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/ DbpA. Mol Cell Biol 26, 2387-2398. (Pubitemid 43346937)
38. Tapia R, Huerta M, Islas S, Avila-Flores A, Lopez-Bayghen E, Weiske J, Huber O, Gonzalez-Mariscal L (2009). Zona occludens-2 inhibits cyclin D1 expression and cell proliferation and exhibits changes in localization along the cell cycle. Mol Biol Cell 20, 1102-1117.
39. Traweger A, Lehner C, Farkas A, Krizbai IA, Tempfer H, Klement E, Guenther B, Bauer HC, Bauer H (2008). Nuclear zonula occludens-2 alters gene expression and junctional stability in epithelial and endothelial cells. Differentiation 76, 99-106.
40. Tsukita S, Furuse M, Itoh M (2001). Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol 2, 285-293. (Pubitemid 33676971)
41. Wittchen ES, Haskins J, Stevenson BR (2003). NZO-3 expression causes global changes to actin cytoskeleton in Madin-Darby canine kidney cells: linking a tight junction protein to Rho GTPases. Mol Biol Cell 14, 1757-1768. (Pubitemid 36583530)
42. Xu J, Kausalya PJ, Phua DC, Ali SM, Hossain Z, Hunziker W (2008).Early embryonic lethality of mice lacking ZO-2, but not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development. Mol Cell Biol 28, 1669-1678.