메뉴 건너뛰기




Volumn 6, Issue MAY, 2015, Pages

Nuclear receptors and endocrine disruptors in fetal and neonatal testes: A gapped landscape

Author keywords

BPA; DES; Human fetal testis; Nuclear receptors; Phthalates

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ANDROGEN RECEPTOR; CELL NUCLEUS RECEPTOR; DIETHYLSTILBESTROL; ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR; LIVER X RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHTHALIC ACID;

EID: 84930944040     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2015.00058     Document Type: Review
Times cited : (41)

References (157)
  • 2
    • 1342322768 scopus 로고    scopus 로고
    • How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health
    • Sharpe RM, Irvine DS. How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health? BMJ (2004) 328:447-51. doi:10.1136/bmj.328.7437.447
    • (2004) BMJ , vol.328 , pp. 447-451
    • Sharpe, R.M.1    Irvine, D.S.2
  • 3
  • 4
    • 0038790021 scopus 로고    scopus 로고
    • Late onset of spermatogenesis and gain of fertility in POG-deficient mice indicate that POG is not necessary for the proliferation of spermatogonia
    • Lu B, Bishop CE. Late onset of spermatogenesis and gain of fertility in POG-deficient mice indicate that POG is not necessary for the proliferation of spermatogonia. Biol Reprod (2003) 69:161-8. doi:10.1095/biolreprod.102.014654
    • (2003) Biol Reprod , vol.69 , pp. 161-168
    • Lu, B.1    Bishop, C.E.2
  • 5
    • 66949136439 scopus 로고    scopus 로고
    • Exposure of the mouse perinatal testis to radiation leads to hypospermia at sexual maturity
    • Forand A, Messiaen S, Habert R, Bernardino-Sgherri J. Exposure of the mouse perinatal testis to radiation leads to hypospermia at sexual maturity. Reproduction (2009) 137:487-95. doi:10.1530/REP-08-0358
    • (2009) Reproduction , vol.137 , pp. 487-495
    • Forand, A.1    Messiaen, S.2    Habert, R.3    Bernardino-Sgherri, J.4
  • 6
    • 0035919207 scopus 로고    scopus 로고
    • Origin, differentiation and regulation of fetal and adult Leydig cells
    • Habert R, Lejeune H, Saez JM. Origin, differentiation and regulation of fetal and adult Leydig cells. Mol Cell Endocrinol (2001) 179:47-74. doi:10.1016/S0303-7207(01)00461-0
    • (2001) Mol Cell Endocrinol , vol.179 , pp. 47-74
    • Habert, R.1    Lejeune, H.2    Saez, J.M.3
  • 7
    • 73249139551 scopus 로고    scopus 로고
    • Steroidogenesis in the fetal testis and its susceptibility to disruption by exogenous compounds
    • Scott HM, Mason JI, Sharpe RM. Steroidogenesis in the fetal testis and its susceptibility to disruption by exogenous compounds. Endocr Rev (2009) 30:883-925. doi:10.1210/er.2009-0016
    • (2009) Endocr Rev , vol.30 , pp. 883-925
    • Scott, H.M.1    Mason, J.I.2    Sharpe, R.M.3
  • 8
    • 84930810987 scopus 로고    scopus 로고
    • The masculinization programming window
    • Welsh M, Suzuki H, Yamada G. The masculinization programming window. Endocr Dev (2014) 27:17-27. doi:10.1159/000363609
    • (2014) Endocr Dev , vol.27 , pp. 17-27
    • Welsh, M.1    Suzuki, H.2    Yamada, G.3
  • 10
    • 79954420469 scopus 로고    scopus 로고
    • Testicular descent: INSL3, testosterone, genes and the intrauterine milieu
    • Bay K, Main KM, Toppari J, Skakkebaek NE. Testicular descent: INSL3, testosterone, genes and the intrauterine milieu. Nat Rev Urol (2011) 8:187-96. doi:10.1038/nrurol.2011.23
    • (2011) Nat Rev Urol , vol.8 , pp. 187-196
    • Bay, K.1    Main, K.M.2    Toppari, J.3    Skakkebaek, N.E.4
  • 11
    • 84898410154 scopus 로고    scopus 로고
    • Insulin-like factor 3 and the HPG axis in the male.
    • Ivell R, Heng K, Anand-Ivell R. Insulin-like factor 3 and the HPG axis in the male. Front Endocrinol (2014) 5:6.
    • (2014) Front Endocrinol , vol.5 , pp. 6
    • Ivell, R.1    Heng, K.2    Anand-Ivell, R.3
  • 12
    • 41749092093 scopus 로고    scopus 로고
    • Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects
    • Sharpe RM, Skakkebaek NE. Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. Fertil Steril (2008) 89:e33-8. doi:10.1016/j.fertnstert.2007.12.026
    • (2008) Fertil Steril , vol.89 , pp. e33-e38
    • Sharpe, R.M.1    Skakkebaek, N.E.2
  • 14
    • 33750503417 scopus 로고    scopus 로고
    • Estrogen effects on fetal and neonatal testicular development
    • Delbes G, Levacher C, Habert R. Estrogen effects on fetal and neonatal testicular development. Reproduction (2006) 132:527-38. doi:10.1530/rep.1.01231
    • (2006) Reproduction , vol.132 , pp. 527-538
    • Delbes, G.1    Levacher, C.2    Habert, R.3
  • 15
    • 33646373730 scopus 로고    scopus 로고
    • Organotypic culture, a powerful model for studying rat and mouse fetal testis development
    • Livera G, Delbes G, Pairault C, Rouiller-Fabre V, Habert R. Organotypic culture, a powerful model for studying rat and mouse fetal testis development. Cell Tissue Res (2006) 324:507-21. doi:10.1007/s00441-006-0167-7
    • (2006) Cell Tissue Res , vol.324 , pp. 507-521
    • Livera, G.1    Delbes, G.2    Pairault, C.3    Rouiller-Fabre, V.4    Habert, R.5
  • 16
    • 75949112154 scopus 로고    scopus 로고
    • Adverse effects of endocrine disruptors on the foetal testis development: focus on the phthalates
    • Habert R, Muczynski V, Lehraiki A, Lambrot R, Lecureuil C, Levacher C, et al. Adverse effects of endocrine disruptors on the foetal testis development: focus on the phthalates. Folia Histochem Cytobiol (2009) 47:S67-74. doi:10.2478/v10042-009-0056-5
    • (2009) Folia Histochem Cytobiol , vol.47 , pp. S67-S74
    • Habert, R.1    Muczynski, V.2    Lehraiki, A.3    Lambrot, R.4    Lecureuil, C.5    Levacher, C.6
  • 17
    • 84924358971 scopus 로고    scopus 로고
    • A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound
    • Eladak S, Grisin T, Moison D, Guerquin MJ, N'tumba-Byn T, Pozzi-Gaudin S, et al. A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound. Fertil Steril (2015) 103:11-21. doi:10.1016/j.fertnstert.2014.11.005
    • (2015) Fertil Steril , vol.103 , pp. 11-21
    • Eladak, S.1    Grisin, T.2    Moison, D.3    Guerquin, M.J.4    N'tumba-Byn, T.5    Pozzi-Gaudin, S.6
  • 18
    • 0022653964 scopus 로고
    • Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
    • Green S, Walter P, Kumar V, Krust A, Bornert JM, Argos P, et al. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (1986) 320:134-9. doi:10.1038/320134a0
    • (1986) Nature , vol.320 , pp. 134-139
    • Green, S.1    Walter, P.2    Kumar, V.3    Krust, A.4    Bornert, J.M.5    Argos, P.6
  • 19
    • 0023664141 scopus 로고
    • Molecular cloning and characterization of rat estrogen receptor cDNA
    • Koike S, Sakai M, Muramatsu M. Molecular cloning and characterization of rat estrogen receptor cDNA. Nucleic Acids Res (1987) 15:2499-513. doi:10.1093/nar/15.6.2499
    • (1987) Nucleic Acids Res , vol.15 , pp. 2499-2513
    • Koike, S.1    Sakai, M.2    Muramatsu, M.3
  • 21
    • 0033574663 scopus 로고    scopus 로고
    • A unified nomenclature system for the nuclear receptor superfamily
    • Nuclear Receptors Nomenclature C. A unified nomenclature system for the nuclear receptor superfamily. Cell (1999) 97:161-3. doi:10.1016/S0092-8674(00)80726-6
    • (1999) Cell , vol.97 , pp. 161-163
  • 22
    • 0035002848 scopus 로고    scopus 로고
    • Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man
    • Williams K, Mckinnell C, Saunders PT, Walker M, Fisher JS, Turner KJ, et al. Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man. Hum Reprod Update (2001) 7:236-47. doi:10.1093/humupd/7.3.236
    • (2001) Hum Reprod Update , vol.7 , pp. 236-247
    • Williams, K.1    Mckinnell, C.2    Saunders, P.T.3    Walker, M.4    Fisher, J.S.5    Turner, K.J.6
  • 23
    • 0026577376 scopus 로고
    • Immunodetection of estrogen receptors in fetal and neonatal male mouse reproductive tracts
    • Greco TL, Furlow JD, Duello TM, Gorski J. Immunodetection of estrogen receptors in fetal and neonatal male mouse reproductive tracts. Endocrinology (1992) 130:421-9. doi:10.1210/en.130.1.421
    • (1992) Endocrinology , vol.130 , pp. 421-429
    • Greco, T.L.1    Furlow, J.D.2    Duello, T.M.3    Gorski, J.4
  • 24
    • 0343986355 scopus 로고    scopus 로고
    • Ontogeny of oestrogen receptor alpha in gonads and sex ducts of fetal and newborn mice
    • Nielsen M, Bjornsdottir S, Hoyer PE, Byskov AG. Ontogeny of oestrogen receptor alpha in gonads and sex ducts of fetal and newborn mice. J Reprod Fertil (2000) 118:195-204. doi:10.1530/jrf.0.1180195
    • (2000) J Reprod Fertil , vol.118 , pp. 195-204
    • Nielsen, M.1    Bjornsdottir, S.2    Hoyer, P.E.3    Byskov, A.G.4
  • 25
    • 17744391814 scopus 로고    scopus 로고
    • Endogenous estrogens inhibit mouse fetal leydig cell development via estrogen receptor alpha
    • Delbes G, Levacher C, Duquenne C, Racine C, Pakarinen P, Habert R. Endogenous estrogens inhibit mouse fetal leydig cell development via estrogen receptor alpha. Endocrinology (2005) 146:2454-61. doi:10.1210/en.2004-1540
    • (2005) Endocrinology , vol.146 , pp. 2454-2461
    • Delbes, G.1    Levacher, C.2    Duquenne, C.3    Racine, C.4    Pakarinen, P.5    Habert, R.6
  • 26
    • 0033968893 scopus 로고    scopus 로고
    • Expression of estrogen receptor beta is developmentally regulated in reproductive tissues of male and female mice
    • Jefferson WN, Couse JF, Banks EP, Korach KS, Newbold RR. Expression of estrogen receptor beta is developmentally regulated in reproductive tissues of male and female mice. Biol Reprod (2000) 62:310-7. doi:10.1095/biolreprod62.2.310
    • (2000) Biol Reprod , vol.62 , pp. 310-317
    • Jefferson, W.N.1    Couse, J.F.2    Banks, E.P.3    Korach, K.S.4    Newbold, R.R.5
  • 27
    • 0031936009 scopus 로고    scopus 로고
    • Expression of oestrogen receptor beta (ER beta) occurs in multiple cell types, including some germ cells, in the rat testis
    • Saunders PT, Fisher JS, Sharpe RM, Millar MR. Expression of oestrogen receptor beta (ER beta) occurs in multiple cell types, including some germ cells, in the rat testis. J Endocrinol (1998) 156:R13-7. doi:10.1677/joe.0.156R013
    • (1998) J Endocrinol , vol.156 , pp. R13-R17
    • Saunders, P.T.1    Fisher, J.S.2    Sharpe, R.M.3    Millar, M.R.4
  • 29
    • 9844257026 scopus 로고    scopus 로고
    • Tissue distribution of estrogen receptors alpha (ER-alpha) and beta (ER-beta) mRNA in the midgestational human fetus
    • Brandenberger AW, Tee MK, Lee JY, Chao V, Jaffe RB. Tissue distribution of estrogen receptors alpha (ER-alpha) and beta (ER-beta) mRNA in the midgestational human fetus. J Clin Endocrinol Metab (1997) 82:3509-12. doi:10.1210/jcem.82.10.4400
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3509-3512
    • Brandenberger, A.W.1    Tee, M.K.2    Lee, J.Y.3    Chao, V.4    Jaffe, R.B.5
  • 30
    • 0035984014 scopus 로고    scopus 로고
    • ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis
    • Saunders PT, Millar MR, Macpherson S, Irvine DS, Groome NP, Evans LR, et al. ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis. J Clin Endocrinol Metab (2002) 87:2706-15. doi:10.1210/jcem.87.6.8619
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2706-2715
    • Saunders, P.T.1    Millar, M.R.2    Macpherson, S.3    Irvine, D.S.4    Groome, N.P.5    Evans, L.R.6
  • 31
    • 0035024422 scopus 로고    scopus 로고
    • Expression and cellular localization of estrogen receptors alpha and beta in the human fetus
    • Takeyama J, Suzuki T, Inoue S, Kaneko C, Nagura H, Harada N, et al. Expression and cellular localization of estrogen receptors alpha and beta in the human fetus. J Clin Endocrinol Metab (2001) 86:2258-62. doi:10.1210/jcem.86.5.7447
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2258-2262
    • Takeyama, J.1    Suzuki, T.2    Inoue, S.3    Kaneko, C.4    Nagura, H.5    Harada, N.6
  • 32
    • 0037242045 scopus 로고    scopus 로고
    • Differential expression of two estrogen receptor beta isoforms in the human fetal testis during the second trimester of pregnancy
    • Gaskell TL, Robinson LL, Groome NP, Anderson RA, Saunders PT. Differential expression of two estrogen receptor beta isoforms in the human fetal testis during the second trimester of pregnancy. J Clin Endocrinol Metab (2003) 88:424-32. doi:10.1210/jc.2002-020811
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 424-432
    • Gaskell, T.L.1    Robinson, L.L.2    Groome, N.P.3    Anderson, R.A.4    Saunders, P.T.5
  • 33
    • 84876426038 scopus 로고    scopus 로고
    • Diethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenografts
    • Mitchell RT, Sharpe RM, Anderson RA, Mckinnell C, Macpherson S, Smith LB, et al. Diethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenografts. PLoS One (2013) 8:e61726. doi:10.1371/journal.pone.0061726
    • (2013) PLoS One , vol.8
    • Mitchell, R.T.1    Sharpe, R.M.2    Anderson, R.A.3    Mckinnell, C.4    Macpherson, S.5    Smith, L.B.6
  • 34
    • 0034486848 scopus 로고    scopus 로고
    • Immunocytochemical localization of estrogen receptors alpha and beta in the human reproductive organs
    • Pelletier G, El-Alfy M. Immunocytochemical localization of estrogen receptors alpha and beta in the human reproductive organs. J Clin Endocrinol Metab (2000) 85:4835-40. doi:10.1210/jcem.85.12.7029
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4835-4840
    • Pelletier, G.1    El-Alfy, M.2
  • 35
    • 0028625491 scopus 로고
    • Insights from the study of animals lacking functional estrogen receptor
    • Korach KS. Insights from the study of animals lacking functional estrogen receptor. Science (1994) 266:1524-7. doi:10.1126/science.7985022
    • (1994) Science , vol.266 , pp. 1524-1527
    • Korach, K.S.1
  • 36
    • 0032499704 scopus 로고    scopus 로고
    • Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene
    • Fisher CR, Graves KH, Parlow AF, Simpson ER. Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc Natl Acad Sci U S A (1998) 95:6965-70. doi:10.1073/pnas.95.12.6965
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6965-6970
    • Fisher, C.R.1    Graves, K.H.2    Parlow, A.F.3    Simpson, E.R.4
  • 39
    • 3042687441 scopus 로고    scopus 로고
    • Estrogen receptor beta-mediated inhibition of male germ cell line development in mice by endogenous estrogens during perinatal life
    • Delbes G, Levacher C, Pairault C, Racine C, Duquenne C, Krust A, et al. Estrogen receptor beta-mediated inhibition of male germ cell line development in mice by endogenous estrogens during perinatal life. Endocrinology (2004) 145:3395-403. doi:10.1210/en.2003-1479
    • (2004) Endocrinology , vol.145 , pp. 3395-3403
    • Delbes, G.1    Levacher, C.2    Pairault, C.3    Racine, C.4    Duquenne, C.5    Krust, A.6
  • 41
    • 84901637163 scopus 로고    scopus 로고
    • The regulation of spermatogenesis by androgens
    • Smith LB, Walker WH. The regulation of spermatogenesis by androgens. Semin Cell Dev Biol (2014) 30:2-13. doi:10.1016/j.semcdb.2014.02.012
    • (2014) Semin Cell Dev Biol , vol.30 , pp. 2-13
    • Smith, L.B.1    Walker, W.H.2
  • 42
  • 43
    • 33847639684 scopus 로고    scopus 로고
    • Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation
    • Merlet J, Racine C, Moreau E, Moreno SG, Habert R. Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation. Proc Natl Acad Sci U S A (2007) 104:3615-20. doi:10.1073/pnas.0611421104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3615-3620
    • Merlet, J.1    Racine, C.2    Moreau, E.3    Moreno, S.G.4    Habert, R.5
  • 44
    • 35148812494 scopus 로고    scopus 로고
    • Development of fetal testicular cells in androgen receptor deficient mice
    • Merlet J, Moreau E, Habert R, Racine C. Development of fetal testicular cells in androgen receptor deficient mice. Cell Cycle (2007) 6:2258-62. doi:10.4161/cc.6.18.4654
    • (2007) Cell Cycle , vol.6 , pp. 2258-2262
    • Merlet, J.1    Moreau, E.2    Habert, R.3    Racine, C.4
  • 45
    • 0038346008 scopus 로고    scopus 로고
    • Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood
    • Sharpe RM, Mckinnell C, Kivlin C, Fisher JS. Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction (2003) 125:769-84. doi:10.1530/rep.0.1250769
    • (2003) Reproduction , vol.125 , pp. 769-784
    • Sharpe, R.M.1    Mckinnell, C.2    Kivlin, C.3    Fisher, J.S.4
  • 46
    • 66149090735 scopus 로고    scopus 로고
    • Lack of androgen receptor expression in sertoli cells accounts for the absence of anti-mullerian hormone repression during early human testis development
    • Boukari K, Meduri G, Brailly-Tabard S, Guibourdenche J, Ciampi ML, Massin N, et al. Lack of androgen receptor expression in sertoli cells accounts for the absence of anti-mullerian hormone repression during early human testis development. J Clin Endocrinol Metab (2009) 94:1818-25. doi:10.1210/jc.2008-1909
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1818-1825
    • Boukari, K.1    Meduri, G.2    Brailly-Tabard, S.3    Guibourdenche, J.4    Ciampi, M.L.5    Massin, N.6
  • 47
    • 84930942868 scopus 로고    scopus 로고
    • Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset leydig cell apoptosis in both mice and men
    • O'Hara L, Mcinnes K, Simitsidellis I, Morgan S, Atanassova N, Slowikowska-Hilczer J, et al. Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset leydig cell apoptosis in both mice and men. FASEB J (2015) 29:894-910. doi:10.1096/fj.14-255729
    • (2015) FASEB J , vol.29 , pp. 894-910
    • O'Hara, L.1    Mcinnes, K.2    Simitsidellis, I.3    Morgan, S.4    Atanassova, N.5    Slowikowska-Hilczer, J.6
  • 49
    • 84877876298 scopus 로고    scopus 로고
    • Altered testicular development as a consequence of increase number of sertoli cell in male lambs exposed prenatally to excess testosterone
    • Rojas-Garcia PP, Recabarren MP, Sir-Petermann T, Rey R, Palma S, Carrasco A, et al. Altered testicular development as a consequence of increase number of sertoli cell in male lambs exposed prenatally to excess testosterone. Endocrine (2013) 43:705-13. doi:10.1007/s12020-012-9818-5
    • (2013) Endocrine , vol.43 , pp. 705-713
    • Rojas-Garcia, P.P.1    Recabarren, M.P.2    Sir-Petermann, T.3    Rey, R.4    Palma, S.5    Carrasco, A.6
  • 50
    • 18044376795 scopus 로고    scopus 로고
    • PPARs: therapeutic targets for metabolic disease
    • Berger JP, Akiyama TE, Meinke PT. PPARs: therapeutic targets for metabolic disease. Trends Pharmacol Sci (2005) 26:244-51. doi:10.1016/j.tips.2005.03.003
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 244-251
    • Berger, J.P.1    Akiyama, T.E.2    Meinke, P.T.3
  • 51
    • 33646810470 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in reproductive tissues: from gametogenesis to parturition
    • Froment P, Gizard F, Defever D, Staels B, Dupont J, Monget P. Peroxisome proliferator-activated receptors in reproductive tissues: from gametogenesis to parturition. J Endocrinol (2006) 189:199-209. doi:10.1677/joe.1.06667
    • (2006) J Endocrinol , vol.189 , pp. 199-209
    • Froment, P.1    Gizard, F.2    Defever, D.3    Staels, B.4    Dupont, J.5    Monget, P.6
  • 52
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology (1996) 137:354-66. doi:10.1210/endo.137.1.8536636
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 53
    • 10044224255 scopus 로고    scopus 로고
    • Role of PPARalpha in mediating the effects of phthalates and metabolites in the liver
    • Lapinskas PJ, Brown S, Leesnitzer LM, Blanchard S, Swanson C, Cattley RC, et al. Role of PPARalpha in mediating the effects of phthalates and metabolites in the liver. Toxicology (2005) 207:149-63. doi:10.1016/j.tox.2004.09.008
    • (2005) Toxicology , vol.207 , pp. 149-163
    • Lapinskas, P.J.1    Brown, S.2    Leesnitzer, L.M.3    Blanchard, S.4    Swanson, C.5    Cattley, R.C.6
  • 55
    • 84868155177 scopus 로고    scopus 로고
    • Cellular and molecular effect of MEHP Involving LXRalpha in human fetal testis and ovary
    • Muczynski V, Lecureuil C, Messiaen S, Guerquin M, N'tumba-Byn T, Moison D, et al. Cellular and molecular effect of MEHP Involving LXRalpha in human fetal testis and ovary. PLoS One (2012) 7:e48266. doi:10.1371/journal.pone.0048266
    • (2012) PLoS One , vol.7
    • Muczynski, V.1    Lecureuil, C.2    Messiaen, S.3    Guerquin, M.4    N'tumba-Byn, T.5    Moison, D.6
  • 56
    • 0036754728 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptors in human testicular cancer and growth inhibition by its agonists
    • Hase T, Yoshimura R, Mitsuhashi M, Segawa Y, Kawahito Y, Wada S, et al. Expression of peroxisome proliferator-activated receptors in human testicular cancer and growth inhibition by its agonists. Urology (2002) 60:542-7. doi:10.1016/S0090-4295(02)01747-8
    • (2002) Urology , vol.60 , pp. 542-547
    • Hase, T.1    Yoshimura, R.2    Mitsuhashi, M.3    Segawa, Y.4    Kawahito, Y.5    Wada, S.6
  • 57
    • 0031969263 scopus 로고    scopus 로고
    • Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice
    • Ward JM, Peters JM, Perella CM, Gonzalez FJ. Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice. Toxicol Pathol (1998) 26:240-6. doi:10.1177/019262339802600208
    • (1998) Toxicol Pathol , vol.26 , pp. 240-246
    • Ward, J.M.1    Peters, J.M.2    Perella, C.M.3    Gonzalez, F.J.4
  • 58
    • 84856084795 scopus 로고    scopus 로고
    • Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency
    • Hannas BR, Lambright CS, Furr J, Evans N, Foster PM, Gray EL, et al. Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency. Toxicol Sci (2012) 125:544-57. doi:10.1093/toxsci/kfr315
    • (2012) Toxicol Sci , vol.125 , pp. 544-557
    • Hannas, B.R.1    Lambright, C.S.2    Furr, J.3    Evans, N.4    Foster, P.M.5    Gray, E.L.6
  • 60
    • 0033213637 scopus 로고    scopus 로고
    • PPAR gamma is required for placental, cardiac, and adipose tissue development
    • Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, et al. PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell (1999) 4:585-95. doi:10.1016/S1097-2765(00)80209-9
    • (1999) Mol Cell , vol.4 , pp. 585-595
    • Barak, Y.1    Nelson, M.C.2    Ong, E.S.3    Jones, Y.Z.4    Ruiz-Lozano, P.5    Chien, K.R.6
  • 62
    • 0035851188 scopus 로고    scopus 로고
    • Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism
    • Lu TT, Repa JJ, Mangelsdorf DJ. Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism. J Biol Chem (2001) 276:37735-8. doi:10.1074/jbc.R100035200
    • (2001) J Biol Chem , vol.276 , pp. 37735-37738
    • Lu, T.T.1    Repa, J.J.2    Mangelsdorf, D.J.3
  • 63
    • 1842424448 scopus 로고    scopus 로고
    • Liver X receptors as potential therapeutic targets for multiple diseases
    • Cao G, Liang Y, Jiang XC, Eacho PI. Liver X receptors as potential therapeutic targets for multiple diseases. Drug News Perspect (2004) 17:35-41. doi:10.1358/dnp.2004.17.1.829024
    • (2004) Drug News Perspect , vol.17 , pp. 35-41
    • Cao, G.1    Liang, Y.2    Jiang, X.C.3    Eacho, P.I.4
  • 65
    • 34250805279 scopus 로고    scopus 로고
    • Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility
    • Volle DH, Mouzat K, Duggavathi R, Siddeek B, Dechelotte P, Sion B, et al. Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility. Mol Endocrinol (2007) 21:1014-27. doi:10.1210/me.2006-0277
    • (2007) Mol Endocrinol , vol.21 , pp. 1014-1027
    • Volle, D.H.1    Mouzat, K.2    Duggavathi, R.3    Siddeek, B.4    Dechelotte, P.5    Sion, B.6
  • 66
    • 33847078808 scopus 로고    scopus 로고
    • Role of the nuclear receptors for oxysterols LXRs in steroidogenic tissues: beyond the "foie gras", the steroids and sex
    • Volle DH, Lobaccaro JM. Role of the nuclear receptors for oxysterols LXRs in steroidogenic tissues: beyond the "foie gras", the steroids and sex? Mol Cell Endocrinol (2007) 26(5-266):183-9. doi:10.1016/j.mce.2006.12.018
    • (2007) Mol Cell Endocrinol , vol.26 , Issue.5-266 , pp. 183-189
    • Volle, D.H.1    Lobaccaro, J.M.2
  • 67
    • 84898831353 scopus 로고    scopus 로고
    • Liver X receptors interfere with the deleterious effect of diethylstilbestrol on testicular physiology
    • Oumeddour A, Viennois E, Caira F, Decourbey C, Maqdasy S, Tahraoui A, et al. Liver X receptors interfere with the deleterious effect of diethylstilbestrol on testicular physiology. Biochem Biophys Res Commun (2014) 446:656-62. doi:10.1016/j.bbrc.2013.12.005
    • (2014) Biochem Biophys Res Commun , vol.446 , pp. 656-662
    • Oumeddour, A.1    Viennois, E.2    Caira, F.3    Decourbey, C.4    Maqdasy, S.5    Tahraoui, A.6
  • 68
    • 84905500669 scopus 로고    scopus 로고
    • Levels of liver X receptors in testicular biopsies of patients with azoospermia.
    • Rondanino C, Ouchchane L, Chauffour C, Marceau G, Dechelotte P, Sion B, et al. Levels of liver X receptors in testicular biopsies of patients with azoospermia. Fertil Steril (2014) 102(361-371):e365. doi:10.1016/j.fertnstert.2014.04.033
    • (2014) Fertil Steril , vol.102 , Issue.361-371
    • Rondanino, C.1    Ouchchane, L.2    Chauffour, C.3    Marceau, G.4    Dechelotte, P.5    Sion, B.6
  • 69
    • 0033636789 scopus 로고    scopus 로고
    • Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
    • Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, Auwerx J, et al. Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol Cell (2000) 6:507-15. doi:10.1016/S1097-2765(00)00050-2
    • (2000) Mol Cell , vol.6 , pp. 507-515
    • Lu, T.T.1    Makishima, M.2    Repa, J.J.3    Schoonjans, K.4    Kerr, T.A.5    Auwerx, J.6
  • 70
    • 0036086509 scopus 로고    scopus 로고
    • Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis
    • Kerr TA, Saeki S, Schneider M, Schaefer K, Berdy S, Redder T, et al. Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis. Dev Cell (2002) 2:713-20. doi:10.1016/S1534-5807(02)00154-5
    • (2002) Dev Cell , vol.2 , pp. 713-720
    • Kerr, T.A.1    Saeki, S.2    Schneider, M.3    Schaefer, K.4    Berdy, S.5    Redder, T.6
  • 71
    • 33846945808 scopus 로고    scopus 로고
    • The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice
    • Volle DH, Duggavathi R, Magnier BC, Houten SM, Cummins CL, Lobaccaro JM, et al. The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice. Genes Dev (2007) 21:303-15. doi:10.1101/gad.409307
    • (2007) Genes Dev , vol.21 , pp. 303-315
    • Volle, D.H.1    Duggavathi, R.2    Magnier, B.C.3    Houten, S.M.4    Cummins, C.L.5    Lobaccaro, J.M.6
  • 73
    • 33646198340 scopus 로고    scopus 로고
    • Retinoid signaling determines germ cell fate in mice
    • Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S, et al. Retinoid signaling determines germ cell fate in mice. Science (2006) 312:596-600. doi:10.1126/science.1125691
    • (2006) Science , vol.312 , pp. 596-600
    • Bowles, J.1    Knight, D.2    Smith, C.3    Wilhelm, D.4    Richman, J.5    Mamiya, S.6
  • 75
    • 0027232797 scopus 로고
    • Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract
    • Sharpe RM, Skakkebaek NE. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet (1993) 341:1392-5. doi:10.1016/0140-6736(93)90953-E
    • (1993) Lancet , vol.341 , pp. 1392-1395
    • Sharpe, R.M.1    Skakkebaek, N.E.2
  • 76
    • 0021322518 scopus 로고
    • Diethylstilbestrol exposure in utero: review of literature.
    • Glaze GM. Diethylstilbestrol exposure in utero: review of literature. J Am Osteopath Assoc (1984) 83:435-8.
    • (1984) J Am Osteopath Assoc , vol.83 , pp. 435-438
    • Glaze, G.M.1
  • 79
    • 0037238481 scopus 로고    scopus 로고
    • The 'oestrogen hypothesis' - where do we stand now
    • Sharpe RM. The 'oestrogen hypothesis' - where do we stand now? Int J Androl (2003) 26:2-15. doi:10.1046/j.1365-2605.2003.00367.x
    • (2003) Int J Androl , vol.26 , pp. 2-15
    • Sharpe, R.M.1
  • 80
    • 0021891678 scopus 로고
    • Effect of ethinyl estradiol on the differentiation of mouse fetal testis
    • Yasuda Y, Kihara T, Tanimura T. Effect of ethinyl estradiol on the differentiation of mouse fetal testis. Teratology (1985) 32:113-8. doi:10.1002/tera.1420320115
    • (1985) Teratology , vol.32 , pp. 113-118
    • Yasuda, Y.1    Kihara, T.2    Tanimura, T.3
  • 81
    • 0021931189 scopus 로고
    • Gonadal dysgenesis induced by prenatal exposure to ethinyl estradiol in mice
    • Yasuda Y, Kihara T, Tanimura T, Nishimura H. Gonadal dysgenesis induced by prenatal exposure to ethinyl estradiol in mice. Teratology (1985) 32:219-27. doi:10.1002/tera.1420320210
    • (1985) Teratology , vol.32 , pp. 219-227
    • Yasuda, Y.1    Kihara, T.2    Tanimura, T.3    Nishimura, H.4
  • 83
    • 0038324382 scopus 로고    scopus 로고
    • Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture
    • Lassurguere J, Livera G, Habert R, Jegou B. Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture. Toxicol Sci (2003) 73:160-9. doi:10.1093/toxsci/kfg065
    • (2003) Toxicol Sci , vol.73 , pp. 160-169
    • Lassurguere, J.1    Livera, G.2    Habert, R.3    Jegou, B.4
  • 84
    • 34547875369 scopus 로고    scopus 로고
    • Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life
    • Delbes G, Duquenne C, Szenker J, Taccoen J, Habert R, Levacher C. Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life. Toxicol Sci (2007) 99:234-43. doi:10.1093/toxsci/kfm160
    • (2007) Toxicol Sci , vol.99 , pp. 234-243
    • Delbes, G.1    Duquenne, C.2    Szenker, J.3    Taccoen, J.4    Habert, R.5    Levacher, C.6
  • 85
    • 2942627949 scopus 로고    scopus 로고
    • Diethylstilbestrol inhibits the expression of the steroidogenic acute regulatory protein in mouse fetal testis
    • Guyot R, Odet F, Leduque P, Forest MG, Le Magueresse-Battistoni B. Diethylstilbestrol inhibits the expression of the steroidogenic acute regulatory protein in mouse fetal testis. Mol Cell Endocrinol (2004) 220:67-75. doi:10.1016/j.mce.2004.03.008
    • (2004) Mol Cell Endocrinol , vol.220 , pp. 67-75
    • Guyot, R.1    Odet, F.2    Leduque, P.3    Forest, M.G.4    Le Magueresse-Battistoni, B.5
  • 86
    • 35548936596 scopus 로고    scopus 로고
    • Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism
    • Cederroth CR, Schaad O, Descombes P, Chambon P, Vassalli JD, Nef S. Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism. Endocrinology (2007) 148:5507-19. doi:10.1210/en.2007-0689
    • (2007) Endocrinology , vol.148 , pp. 5507-5519
    • Cederroth, C.R.1    Schaad, O.2    Descombes, P.3    Chambon, P.4    Vassalli, J.D.5    Nef, S.6
  • 87
    • 3042771831 scopus 로고    scopus 로고
    • Gene expression profiling identifies liver X receptor alpha as an estrogen-regulated gene in mouse adipose tissue
    • Lundholm L, Moverare S, Steffensen KR, Nilsson M, Otsuki M, Ohlsson C, et al. Gene expression profiling identifies liver X receptor alpha as an estrogen-regulated gene in mouse adipose tissue. J Mol Endocrinol (2004) 32:879-92. doi:10.1677/jme.0.0320879
    • (2004) J Mol Endocrinol , vol.32 , pp. 879-892
    • Lundholm, L.1    Moverare, S.2    Steffensen, K.R.3    Nilsson, M.4    Otsuki, M.5    Ohlsson, C.6
  • 88
    • 34547475143 scopus 로고    scopus 로고
    • Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor
    • Gong H, Guo P, Zhai Y, Zhou J, Uppal H, Jarzynka MJ, et al. Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor. Mol Endocrinol (2007) 21:1781-90. doi:10.1210/me.2007-0187
    • (2007) Mol Endocrinol , vol.21 , pp. 1781-1790
    • Gong, H.1    Guo, P.2    Zhai, Y.3    Zhou, J.4    Uppal, H.5    Jarzynka, M.J.6
  • 89
    • 72849152935 scopus 로고    scopus 로고
    • The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice
    • Volle DH, Decourteix M, Garo E, Mcneilly J, Fenichel P, Auwerx J, et al. The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice. J Clin Invest (2009) 119:3752-64. doi:10.1172/JCI38521
    • (2009) J Clin Invest , vol.119 , pp. 3752-3764
    • Volle, D.H.1    Decourteix, M.2    Garo, E.3    Mcneilly, J.4    Fenichel, P.5    Auwerx, J.6
  • 90
    • 84871274369 scopus 로고    scopus 로고
    • Differential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell function
    • N'Tumba-Byn T, Moison D, Lacroix M, Lecureuil C, Lesage L, Prud'homme S, et al. Differential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell function. PLoS One (2012) 7:e51579. doi:10.1371/journal.pone.0051579
    • (2012) PLoS One , vol.7
    • N'Tumba-Byn, T.1    Moison, D.2    Lacroix, M.3    Lecureuil, C.4    Lesage, L.5    Prud'homme, S.6
  • 92
    • 1842434975 scopus 로고    scopus 로고
    • Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome
    • Fisher JS. Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome. Reproduction (2004) 127:305-15. doi:10.1530/rep.1.00025
    • (2004) Reproduction , vol.127 , pp. 305-315
    • Fisher, J.S.1
  • 93
    • 64049090287 scopus 로고    scopus 로고
    • Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro
    • Chauvigne F, Menuet A, Lesne L, Chagnon MC, Chevrier C, Regnier JF, et al. Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro. Environ Health Perspect (2009) 117:515-21. doi:10.1289/ehp.11870
    • (2009) Environ Health Perspect , vol.117 , pp. 515-521
    • Chauvigne, F.1    Menuet, A.2    Lesne, L.3    Chagnon, M.C.4    Chevrier, C.5    Regnier, J.F.6
  • 94
    • 60749089958 scopus 로고    scopus 로고
    • Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production
    • Lambrot R, Muczynski V, Lecureuil C, Angenard G, Coffigny H, Pairault C, et al. Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production. Environ Health Perspect (2009) 117:32-7. doi:10.1289/ehp.11146
    • (2009) Environ Health Perspect , vol.117 , pp. 32-37
    • Lambrot, R.1    Muczynski, V.2    Lecureuil, C.3    Angenard, G.4    Coffigny, H.5    Pairault, C.6
  • 95
    • 70349284889 scopus 로고    scopus 로고
    • Phthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanism
    • Lehraiki A, Racine C, Krust A, Habert R, Levacher C. Phthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanism. Toxicol Sci (2009) 111:372-82. doi:10.1093/toxsci/kfp153
    • (2009) Toxicol Sci , vol.111 , pp. 372-382
    • Lehraiki, A.1    Racine, C.2    Krust, A.3    Habert, R.4    Levacher, C.5
  • 96
    • 23744469802 scopus 로고    scopus 로고
    • Decrease in anogenital distance among male infants with prenatal phthalate exposure
    • Swan SH, Main KM, Liu F, Stewart SL, Kruse RL, Calafat AM, et al. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect (2005) 113:1056-61. doi:10.1289/ehp.8100
    • (2005) Environ Health Perspect , vol.113 , pp. 1056-1061
    • Swan, S.H.1    Main, K.M.2    Liu, F.3    Stewart, S.L.4    Kruse, R.L.5    Calafat, A.M.6
  • 97
    • 56949103057 scopus 로고    scopus 로고
    • Association between prenatal exposure to phthalates and the health of newborns
    • Huang PC, Kuo PL, Chou YY, Lin SJ, Lee CC. Association between prenatal exposure to phthalates and the health of newborns. Environ Int (2009) 35:14-20. doi:10.1016/j.envint.2008.05.012
    • (2009) Environ Int , vol.35 , pp. 14-20
    • Huang, P.C.1    Kuo, P.L.2    Chou, Y.Y.3    Lin, S.J.4    Lee, C.C.5
  • 98
    • 0038575340 scopus 로고    scopus 로고
    • Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate
    • Fisher JS, Macpherson S, Marchetti N, Sharpe RM. Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate. Hum Reprod (2003) 18:1383-94. doi:10.1093/humrep/deg273
    • (2003) Hum Reprod , vol.18 , pp. 1383-1394
    • Fisher, J.S.1    Macpherson, S.2    Marchetti, N.3    Sharpe, R.M.4
  • 99
    • 84924419854 scopus 로고    scopus 로고
    • Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetus
    • Habert R, Livera G, Rouiller-Fabre V. Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetus. Basic Clin Androl (2014) 24:14. doi:10.1186/2051-4190-24-14
    • (2014) Basic Clin Androl , vol.24 , pp. 14
    • Habert, R.1    Livera, G.2    Rouiller-Fabre, V.3
  • 100
    • 84896355781 scopus 로고    scopus 로고
    • Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors
    • Habert R, Muczynski V, Grisin T, Moison D, Messiaen S, Frydman R, et al. Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors. Reproduction (2014) 147:R119-29. doi:10.1530/REP-13-0497
    • (2014) Reproduction , vol.147 , pp. R119-R129
    • Habert, R.1    Muczynski, V.2    Grisin, T.3    Moison, D.4    Messiaen, S.5    Frydman, R.6
  • 102
    • 84863393330 scopus 로고    scopus 로고
    • Do phthalates affect steroidogenesis by the human fetal testis? Exposure of human fetal testis xenografts to di-n-butyl phthalate
    • Mitchell RT, Childs AJ, Anderson RA, Van Den Driesche S, Saunders PT, Mckinnell C, et al. Do phthalates affect steroidogenesis by the human fetal testis? Exposure of human fetal testis xenografts to di-n-butyl phthalate. J Clin Endocrinol Metab (2012) 97:E341-8. doi:10.1210/jc.2011-2411
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. E341-E348
    • Mitchell, R.T.1    Childs, A.J.2    Anderson, R.A.3    Van Den Driesche, S.4    Saunders, P.T.5    Mckinnell, C.6
  • 103
    • 84894346426 scopus 로고    scopus 로고
    • Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay
    • Spade DJ, Hall SJ, Saffarini CM, Huse SM, Mcdonnell EV, Boekelheide K. Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay. Toxicol Sci (2014) 138:148-60. doi:10.1093/toxsci/kft266
    • (2014) Toxicol Sci , vol.138 , pp. 148-160
    • Spade, D.J.1    Hall, S.J.2    Saffarini, C.M.3    Huse, S.M.4    Mcdonnell, E.V.5    Boekelheide, K.6
  • 104
    • 0037497143 scopus 로고    scopus 로고
    • Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate
    • Barlow NJ, Phillips SL, Wallace DG, Sar M, Gaido KW, Foster PM. Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate. Toxicol Sci (2003) 73:431-41. doi:10.1093/toxsci/kfg087
    • (2003) Toxicol Sci , vol.73 , pp. 431-441
    • Barlow, N.J.1    Phillips, S.L.2    Wallace, D.G.3    Sar, M.4    Gaido, K.W.5    Foster, P.M.6
  • 105
    • 33751241130 scopus 로고    scopus 로고
    • Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation
    • Ferrara D, Hallmark N, Scott H, Brown R, Mckinnell C, Mahood IK, et al. Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation. Endocrinology (2006) 147:5352-62. doi:10.1210/en.2006-0527
    • (2006) Endocrinology , vol.147 , pp. 5352-5362
    • Ferrara, D.1    Hallmark, N.2    Scott, H.3    Brown, R.4    Mckinnell, C.5    Mahood, I.K.6
  • 106
    • 45149100988 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence
    • Latini G, Scoditti E, Verrotti A, De Felice C, Massaro M. Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence. PPAR Res (2008) 2008:359267. doi:10.1155/2008/359267
    • (2008) PPAR Res , vol.2008
    • Latini, G.1    Scoditti, E.2    Verrotti, A.3    De Felice, C.4    Massaro, M.5
  • 107
    • 33745204653 scopus 로고    scopus 로고
    • Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver
    • Rusyn I, Peters JM, Cunningham ML. Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver. Crit Rev Toxicol (2006) 36:459-79. doi:10.1080/10408440600779065
    • (2006) Crit Rev Toxicol , vol.36 , pp. 459-479
    • Rusyn, I.1    Peters, J.M.2    Cunningham, M.L.3
  • 108
    • 0041352906 scopus 로고    scopus 로고
    • Activation of PPARalpha and PPARgamma by environmental phthalate monoesters
    • Hurst CH, Waxman DJ. Activation of PPARalpha and PPARgamma by environmental phthalate monoesters. Toxicol Sci (2003) 74:297-308. doi:10.1093/toxsci/kfg145
    • (2003) Toxicol Sci , vol.74 , pp. 297-308
    • Hurst, C.H.1    Waxman, D.J.2
  • 109
    • 0032585881 scopus 로고    scopus 로고
    • Trans-activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals
    • Maloney EK, Waxman DJ. Trans-activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals. Toxicol Appl Pharmacol (1999) 161:209-18. doi:10.1006/taap.1999.8809
    • (1999) Toxicol Appl Pharmacol , vol.161 , pp. 209-218
    • Maloney, E.K.1    Waxman, D.J.2
  • 110
    • 4444352514 scopus 로고    scopus 로고
    • Environmental phthalate monoesters activate pregnane X receptor-mediated transcription
    • Hurst CH, Waxman DJ. Environmental phthalate monoesters activate pregnane X receptor-mediated transcription. Toxicol Appl Pharmacol (2004) 199:266-74. doi:10.1016/j.taap.2003.11.028
    • (2004) Toxicol Appl Pharmacol , vol.199 , pp. 266-274
    • Hurst, C.H.1    Waxman, D.J.2
  • 112
    • 33646584544 scopus 로고    scopus 로고
    • Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis
    • Borch J, Metzdorff SB, Vinggaard AM, Brokken L, Dalgaard M. Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis. Toxicology (2006) 223:144-55. doi:10.1016/j.tox.2006.03.015
    • (2006) Toxicology , vol.223 , pp. 144-155
    • Borch, J.1    Metzdorff, S.B.2    Vinggaard, A.M.3    Brokken, L.4    Dalgaard, M.5
  • 113
    • 49849083537 scopus 로고    scopus 로고
    • Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats
    • Boberg J, Metzdorff S, Wortziger R, Axelstad M, Brokken L, Vinggaard AM, et al. Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats. Toxicology (2008) 250:75-81. doi:10.1016/j.tox.2008.05.020
    • (2008) Toxicology , vol.250 , pp. 75-81
    • Boberg, J.1    Metzdorff, S.2    Wortziger, R.3    Axelstad, M.4    Brokken, L.5    Vinggaard, A.M.6
  • 114
    • 34547164038 scopus 로고    scopus 로고
    • Di(2-ethylhexyl) phthalate induces apoptosis through peroxisome proliferators-activated receptor-gamma and ERK 1/2 activation in testis of Sprague-Dawley rats
    • Ryu JY, Whang J, Park H, Im JY, Kim J, Ahn MY, et al. Di(2-ethylhexyl) phthalate induces apoptosis through peroxisome proliferators-activated receptor-gamma and ERK 1/2 activation in testis of Sprague-Dawley rats. J Toxicol Environ Health A (2007) 70:1296-303. doi:10.1080/15287390701432160
    • (2007) J Toxicol Environ Health A , vol.70 , pp. 1296-1303
    • Ryu, J.Y.1    Whang, J.2    Park, H.3    Im, J.Y.4    Kim, J.5    Ahn, M.Y.6
  • 115
    • 84870177747 scopus 로고    scopus 로고
    • Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol
    • Klinefelter GR, Laskey JW, Winnik WM, Suarez JD, Roberts NL, Strader LF, et al. Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol. Reproduction (2012) 144:747-61. doi:10.1530/REP-12-0266
    • (2012) Reproduction , vol.144 , pp. 747-761
    • Klinefelter, G.R.1    Laskey, J.W.2    Winnik, W.M.3    Suarez, J.D.4    Roberts, N.L.5    Strader, L.F.6
  • 116
    • 84860526309 scopus 로고    scopus 로고
    • Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: in vitro and in vivo approaches
    • Muczynski V, Cravedi JP, Lehraiki A, Levacher C, Moison D, Lecureuil C, et al. Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: in vitro and in vivo approaches. Toxicol Appl Pharmacol (2012) 261:97-104. doi:10.1016/j.taap.2012.03.016
    • (2012) Toxicol Appl Pharmacol , vol.261 , pp. 97-104
    • Muczynski, V.1    Cravedi, J.P.2    Lehraiki, A.3    Levacher, C.4    Moison, D.5    Lecureuil, C.6
  • 117
    • 51149188436 scopus 로고
    • Synthetic oestrogenic agents without the phenanthrene nucleus
    • Dodds EC, Lawson W. Synthetic oestrogenic agents without the phenanthrene nucleus. Nature (1936) 137:996. doi:10.1038/137996a0
    • (1936) Nature , vol.137 , pp. 996
    • Dodds, E.C.1    Lawson, W.2
  • 118
    • 33845868010 scopus 로고    scopus 로고
    • Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland
    • Vandenberg LN, Maffini MV, Wadia PR, Sonnenschein C, Rubin BS, Soto AM. Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland. Endocrinology (2007) 148:116-27. doi:10.1210/en.2006-0561
    • (2007) Endocrinology , vol.148 , pp. 116-127
    • Vandenberg, L.N.1    Maffini, M.V.2    Wadia, P.R.3    Sonnenschein, C.4    Rubin, B.S.5    Soto, A.M.6
  • 119
    • 78650054660 scopus 로고    scopus 로고
    • Viable skin efficiently absorbs and metabolizes bisphenol A
    • Zalko D, Jacques C, Duplan H, Bruel S, Perdu E. Viable skin efficiently absorbs and metabolizes bisphenol A. Chemosphere (2011) 82:424-30. doi:10.1016/j.chemosphere.2010.09.058
    • (2011) Chemosphere , vol.82 , pp. 424-430
    • Zalko, D.1    Jacques, C.2    Duplan, H.3    Bruel, S.4    Perdu, E.5
  • 120
    • 84884306178 scopus 로고    scopus 로고
    • Bisphenol A and human health: a review of the literature
    • Rochester JR. Bisphenol A and human health: a review of the literature. Reprod Toxicol (2013) 42:132-55. doi:10.1016/j.reprotox.2013.08.008
    • (2013) Reprod Toxicol , vol.42 , pp. 132-155
    • Rochester, J.R.1
  • 121
    • 80053944927 scopus 로고    scopus 로고
    • In utero exposure to bisphenol-A and anogenital distance of male offspring
    • Miao M, Yuan W, He Y, Zhou Z, Wang J, Gao E, et al. In utero exposure to bisphenol-A and anogenital distance of male offspring. Birth Defects Res A Clin Mol Teratol (2011) 91:867-72. doi:10.1002/bdra.22845
    • (2011) Birth Defects Res A Clin Mol Teratol , vol.91 , pp. 867-872
    • Miao, M.1    Yuan, W.2    He, Y.3    Zhou, Z.4    Wang, J.5    Gao, E.6
  • 122
    • 84864832738 scopus 로고    scopus 로고
    • The association between some endocrine disruptors and hypospadias in biological samples
    • Choi H, Kim J, Im Y, Lee S, Kim Y. The association between some endocrine disruptors and hypospadias in biological samples. J Environ Sci Health A Tox Hazard Subst Environ Eng (2012) 47:2173-9. doi:10.1080/10934529.2012.680387
    • (2012) J Environ Sci Health A Tox Hazard Subst Environ Eng , vol.47 , pp. 2173-2179
    • Choi, H.1    Kim, J.2    Im, Y.3    Lee, S.4    Kim, Y.5
  • 123
    • 84858395602 scopus 로고    scopus 로고
    • Unconjugated bisphenol A cord blood levels in boys with descended or undescended testes
    • Fenichel P, Dechaux H, Harthe C, Gal J, Ferrari P, Pacini P, et al. Unconjugated bisphenol A cord blood levels in boys with descended or undescended testes. Hum Reprod (2012) 27:983-90. doi:10.1093/humrep/der451
    • (2012) Hum Reprod , vol.27 , pp. 983-990
    • Fenichel, P.1    Dechaux, H.2    Harthe, C.3    Gal, J.4    Ferrari, P.5    Pacini, P.6
  • 124
    • 84880331278 scopus 로고    scopus 로고
    • Bisphenol A: an endocrine and metabolic disruptor
    • Fenichel P, Chevalier N, Brucker-Davis F. Bisphenol A: an endocrine and metabolic disruptor. Ann Endocrinol (Paris) (2013) 74:211-20. doi:10.1016/j.ando.2013.04.002
    • (2013) Ann Endocrinol (Paris) , vol.74 , pp. 211-220
    • Fenichel, P.1    Chevalier, N.2    Brucker-Davis, F.3
  • 125
    • 33746546294 scopus 로고    scopus 로고
    • Effect of prenatal exposure to bisphenol A on the serum testosterone concentration of rats at birth
    • Tanaka M, Nakaya S, Katayama M, Leffers H, Nozawa S, Nakazawa R, et al. Effect of prenatal exposure to bisphenol A on the serum testosterone concentration of rats at birth. Hum Exp Toxicol (2006) 25:369-73. doi:10.1191/0960327106ht638oa
    • (2006) Hum Exp Toxicol , vol.25 , pp. 369-373
    • Tanaka, M.1    Nakaya, S.2    Katayama, M.3    Leffers, H.4    Nozawa, S.5    Nakazawa, R.6
  • 126
    • 34247118406 scopus 로고    scopus 로고
    • Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure
    • Murray TJ, Maffini MV, Ucci AA, Sonnenschein C, Soto AM. Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure. Reprod Toxicol (2007) 23:383-90. doi:10.1016/j.reprotox.2006.10.002
    • (2007) Reprod Toxicol , vol.23 , pp. 383-390
    • Murray, T.J.1    Maffini, M.V.2    Ucci, A.A.3    Sonnenschein, C.4    Soto, A.M.5
  • 127
    • 0036808253 scopus 로고    scopus 로고
    • Effects of in utero and lactational exposure to bisphenol A on somatic growth and anogenital distance in F1 rat offspring
    • Kobayashi K, Miyagawa M, Wang RS, Sekiguchi S, Suda M, Honma T. Effects of in utero and lactational exposure to bisphenol A on somatic growth and anogenital distance in F1 rat offspring. Ind Health (2002) 40:375-81. doi:10.2486/indhealth.40.375
    • (2002) Ind Health , vol.40 , pp. 375-381
    • Kobayashi, K.1    Miyagawa, M.2    Wang, R.S.3    Sekiguchi, S.4    Suda, M.5    Honma, T.6
  • 128
    • 0035996069 scopus 로고    scopus 로고
    • Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats
    • Tyl RW, Myers CB, Marr MC, Thomas BF, Keimowitz AR, Brine DR, et al. Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats. Toxicol Sci (2002) 68:121-46. doi:10.1093/toxsci/68.1.121
    • (2002) Toxicol Sci , vol.68 , pp. 121-146
    • Tyl, R.W.1    Myers, C.B.2    Marr, M.C.3    Thomas, B.F.4    Keimowitz, A.R.5    Brine, D.R.6
  • 129
    • 40949155758 scopus 로고    scopus 로고
    • Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat
    • Howdeshell KL, Furr J, Lambright CR, Wilson VS, Ryan BC, Gray LE Jr. Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat. Toxicol Sci (2008) 102:371-82. doi:10.1093/toxsci/kfm306
    • (2008) Toxicol Sci , vol.102 , pp. 371-382
    • Howdeshell, K.L.1    Furr, J.2    Lambright, C.R.3    Wilson, V.S.4    Ryan, B.C.5    Gray LE, Jr.6
  • 130
    • 83455207980 scopus 로고    scopus 로고
    • Effects of in utero exposure to bisphenol A or diethylstilbestrol on the adult male reproductive system
    • LaRocca J, Boyajian A, Brown C, Smith SD, Hixon M. Effects of in utero exposure to bisphenol A or diethylstilbestrol on the adult male reproductive system. Birth Defects Res B Dev Reprod Toxicol (2011) 92:526-33. doi:10.1002/bdrb.20336
    • (2011) Birth Defects Res B Dev Reprod Toxicol , vol.92 , pp. 526-533
    • LaRocca, J.1    Boyajian, A.2    Brown, C.3    Smith, S.D.4    Hixon, M.5
  • 131
    • 70449108111 scopus 로고    scopus 로고
    • Perinatal exposure of rats to bisphenol A affects the fertility of male offspring
    • Salian S, Doshi T, Vanage G. Perinatal exposure of rats to bisphenol A affects the fertility of male offspring. Life Sci (2009) 85:742-52. doi:10.1016/j.lfs.2009.10.004
    • (2009) Life Sci , vol.85 , pp. 742-752
    • Salian, S.1    Doshi, T.2    Vanage, G.3
  • 132
    • 84863734322 scopus 로고    scopus 로고
    • Fetal exposure to bisphenol A affects the primordial follicle formation by inhibiting the meiotic progression of oocytes
    • Zhang HQ, Zhang XF, Zhang LJ, Chao HH, Pan B, Feng YM, et al. Fetal exposure to bisphenol A affects the primordial follicle formation by inhibiting the meiotic progression of oocytes. Mol Biol Rep (2012) 39:5651-7. doi:10.1007/s11033-011-1372-3
    • (2012) Mol Biol Rep , vol.39 , pp. 5651-5657
    • Zhang, H.Q.1    Zhang, X.F.2    Zhang, L.J.3    Chao, H.H.4    Pan, B.5    Feng, Y.M.6
  • 133
    • 84882795488 scopus 로고    scopus 로고
    • In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors
    • Molina-Molina JM, Amaya E, Grimaldi M, Saenz JM, Real M, Fernandez MF, et al. In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors. Toxicol Appl Pharmacol (2013) 272:127-36. doi:10.1016/j.taap.2013.05.015
    • (2013) Toxicol Appl Pharmacol , vol.272 , pp. 127-136
    • Molina-Molina, J.M.1    Amaya, E.2    Grimaldi, M.3    Saenz, J.M.4    Real, M.5    Fernandez, M.F.6
  • 134
    • 0031733298 scopus 로고    scopus 로고
    • Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta
    • Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, Van Der Saag PT, et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology (1998) 139:4252-63. doi:10.1210/endo.139.10.6216
    • (1998) Endocrinology , vol.139 , pp. 4252-4263
    • Kuiper, G.G.1    Lemmen, J.G.2    Carlsson, B.3    Corton, J.C.4    Safe, S.H.5    Van Der Saag, P.T.6
  • 136
    • 0037205916 scopus 로고    scopus 로고
    • Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit alpha and beta estrogen activities and antiandrogen activity in reporter cell lines
    • Paris F, Balaguer P, Terouanne B, Servant N, Lacoste C, Cravedi JP, et al. Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit alpha and beta estrogen activities and antiandrogen activity in reporter cell lines. Mol Cell Endocrinol (2002) 193:43-9. doi:10.1016/S0303-7207(02)00094-1
    • (2002) Mol Cell Endocrinol , vol.193 , pp. 43-49
    • Paris, F.1    Balaguer, P.2    Terouanne, B.3    Servant, N.4    Lacoste, C.5    Cravedi, J.P.6
  • 137
    • 80052305965 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is a target for halogenated analogs of bisphenol A
    • Riu A, Grimaldi M, Le Maire A, Bey G, Phillips K, Boulahtouf A, et al. Peroxisome proliferator-activated receptor gamma is a target for halogenated analogs of bisphenol A. Environ Health Perspect (2011) 119:1227-32. doi:10.1289/ehp.1003328
    • (2011) Environ Health Perspect , vol.119 , pp. 1227-1232
    • Riu, A.1    Grimaldi, M.2    Le Maire, A.3    Bey, G.4    Phillips, K.5    Boulahtouf, A.6
  • 138
    • 80051703928 scopus 로고    scopus 로고
    • Characterization of novel ligands of ERalpha, Erbeta, and PPARgamma: the case of halogenated bisphenol A and their conjugated metabolites
    • Riu A, Le Maire A, Grimaldi M, Audebert M, Hillenweck A, Bourguet W, et al. Characterization of novel ligands of ERalpha, Erbeta, and PPARgamma: the case of halogenated bisphenol A and their conjugated metabolites. Toxicol Sci (2011) 122:372-82. doi:10.1093/toxsci/kfr132
    • (2011) Toxicol Sci , vol.122 , pp. 372-382
    • Riu, A.1    Le Maire, A.2    Grimaldi, M.3    Audebert, M.4    Hillenweck, A.5    Bourguet, W.6
  • 139
    • 84885409730 scopus 로고    scopus 로고
    • Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect
    • Pereira-Fernandes A, Demaegdt H, Vandermeiren K, Hectors TL, Jorens PG, Blust R, et al. Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect. PLoS One (2013) 8:e77481. doi:10.1371/journal.pone.0077481
    • (2013) PLoS One , vol.8
    • Pereira-Fernandes, A.1    Demaegdt, H.2    Vandermeiren, K.3    Hectors, T.L.4    Jorens, P.G.5    Blust, R.6
  • 140
    • 84907856004 scopus 로고    scopus 로고
    • Is bisphenol S a safe substitute for bisphenol A in terms of metabolic function? An in vitro study
    • Helies-Toussaint C, Peyre L, Costanzo C, Chagnon MC, Rahmani R. Is bisphenol S a safe substitute for bisphenol A in terms of metabolic function? An in vitro study. Toxicol Appl Pharmacol (2014) 280:224-35. doi:10.1016/j.taap.2014.07.025
    • (2014) Toxicol Appl Pharmacol , vol.280 , pp. 224-235
    • Helies-Toussaint, C.1    Peyre, L.2    Costanzo, C.3    Chagnon, M.C.4    Rahmani, R.5
  • 142
    • 84856385743 scopus 로고    scopus 로고
    • Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver
    • Marmugi A, Ducheix S, Lasserre F, Polizzi A, Paris A, Priymenko N, et al. Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver. Hepatology (2012) 55:395-407. doi:10.1002/hep.24685
    • (2012) Hepatology , vol.55 , pp. 395-407
    • Marmugi, A.1    Ducheix, S.2    Lasserre, F.3    Polizzi, A.4    Paris, A.5    Priymenko, N.6
  • 143
    • 0027428381 scopus 로고
    • Developmental effects of endocrine-disrupting chemicals in wildlife and humans
    • Colborn T, Vom Saal FS, Soto AM. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Perspect (1993) 101:378-84. doi:10.1289/ehp.93101378
    • (1993) Environ Health Perspect , vol.101 , pp. 378-384
    • Colborn, T.1    Vom Saal, F.S.2    Soto, A.M.3
  • 144
    • 0032052810 scopus 로고    scopus 로고
    • An updated review of environmental estrogen and androgen mimics and antagonists
    • Sonnenschein C, Soto AM. An updated review of environmental estrogen and androgen mimics and antagonists. J Steroid Biochem Mol Biol (1998) 65:143-50. doi:10.1016/S0960-0760(98)00027-2
    • (1998) J Steroid Biochem Mol Biol , vol.65 , pp. 143-150
    • Sonnenschein, C.1    Soto, A.M.2
  • 145
    • 33645215636 scopus 로고    scopus 로고
    • Reproductive dysgenesis in wildlife: a comparative view
    • Edwards TM, Moore BC, Guillette LJ Jr. Reproductive dysgenesis in wildlife: a comparative view. Int J Androl (2006) 29:109-21. doi:10.1111/j.1365-2605.2005.00631.x
    • (2006) Int J Androl , vol.29 , pp. 109-121
    • Edwards, T.M.1    Moore, B.C.2    Guillette LJ, Jr.3
  • 146
    • 84859373425 scopus 로고    scopus 로고
    • Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
    • Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, Lee DH, et al. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev (2012) 33:378-455. doi:10.1210/er.2011-1050
    • (2012) Endocr Rev , vol.33 , pp. 378-455
    • Vandenberg, L.N.1    Colborn, T.2    Hayes, T.B.3    Heindel, J.J.4    Jacobs Jr, D.R.5    Lee, D.H.6
  • 147
    • 84902369815 scopus 로고    scopus 로고
    • Non-monotonic dose responses in studies of endocrine disrupting chemicals: bisphenol a as a case study
    • Vandenberg LN. Non-monotonic dose responses in studies of endocrine disrupting chemicals: bisphenol a as a case study. Dose Response (2014) 12:259-76. doi:10.2203/dose-response.13-020.Vandenberg
    • (2014) Dose Response , vol.12 , pp. 259-276
    • Vandenberg, L.N.1
  • 148
    • 73149091025 scopus 로고    scopus 로고
    • Di (n-butyl) phthalate inhibits testosterone synthesis through a glucocorticoid-mediated pathway in rats
    • Xiao-feng Z, Nai-Qiang Q, Jing Z, Zi L, Yang Z. Di (n-butyl) phthalate inhibits testosterone synthesis through a glucocorticoid-mediated pathway in rats. Int J Toxicol (2009) 28:448-56. doi:10.1177/1091581809342596
    • (2009) Int J Toxicol , vol.28 , pp. 448-456
    • Xiao-feng, Z.1    Nai-Qiang, Q.2    Jing, Z.3    Zi, L.4    Yang, Z.5
  • 149
    • 71949127570 scopus 로고    scopus 로고
    • In utero exposure to di-(2-ethylhexyl) phthalate decreases mineralocorticoid receptor expression in the adult testis
    • Martinez-Arguelles DB, Culty M, Zirkin BR, Papadopoulos V. In utero exposure to di-(2-ethylhexyl) phthalate decreases mineralocorticoid receptor expression in the adult testis. Endocrinology (2009) 150:5575-85. doi:10.1210/en.2009-0847
    • (2009) Endocrinology , vol.150 , pp. 5575-5585
    • Martinez-Arguelles, D.B.1    Culty, M.2    Zirkin, B.R.3    Papadopoulos, V.4
  • 150
    • 40949108026 scopus 로고    scopus 로고
    • Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma
    • Okada H, Tokunaga T, Liu X, Takayanagi S, Matsushima A, Shimohigashi Y. Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma. Environ Health Perspect (2008) 116:32-8. doi:10.1289/ehp.10587
    • (2008) Environ Health Perspect , vol.116 , pp. 32-38
    • Okada, H.1    Tokunaga, T.2    Liu, X.3    Takayanagi, S.4    Matsushima, A.5    Shimohigashi, Y.6
  • 151
    • 79952179448 scopus 로고    scopus 로고
    • Minireview: extranuclear steroid receptors: roles in modulation of cell functions
    • Levin ER. Minireview: extranuclear steroid receptors: roles in modulation of cell functions. Mol Endocrinol (2011) 25:377-84. doi:10.1210/me.2010-0284
    • (2011) Mol Endocrinol , vol.25 , pp. 377-384
    • Levin, E.R.1
  • 152
    • 67650908738 scopus 로고    scopus 로고
    • Low doses of bisphenol A promote human seminoma cell proliferation by activating PKA and PKG via a membrane G-protein-coupled estrogen receptor
    • Bouskine A, Nebout M, Brucker-Davis F, Benahmed M, Fenichel P. Low doses of bisphenol A promote human seminoma cell proliferation by activating PKA and PKG via a membrane G-protein-coupled estrogen receptor. Environ Health Perspect (2009) 117:1053-8. doi:10.1289/ehp.0800367
    • (2009) Environ Health Perspect , vol.117 , pp. 1053-1058
    • Bouskine, A.1    Nebout, M.2    Brucker-Davis, F.3    Benahmed, M.4    Fenichel, P.5
  • 153
    • 84859360984 scopus 로고    scopus 로고
    • GPR30, the non-classical membrane G protein related estrogen receptor, is overexpressed in human seminoma and promotes seminoma cell proliferation
    • Chevalier N, Vega A, Bouskine A, Siddeek B, Michiels JF, Chevallier D, et al. GPR30, the non-classical membrane G protein related estrogen receptor, is overexpressed in human seminoma and promotes seminoma cell proliferation. PLoS One (2012) 7:e34672. doi:10.1371/journal.pone.0034672
    • (2012) PLoS One , vol.7
    • Chevalier, N.1    Vega, A.2    Bouskine, A.3    Siddeek, B.4    Michiels, J.F.5    Chevallier, D.6
  • 154
    • 84903698288 scopus 로고    scopus 로고
    • Estrogen-related receptor gamma is an in vivo receptor of bisphenol A
    • Tohme M, Prud'homme SM, Boulahtouf A, Samarut E, Brunet F, Bernard L, et al. Estrogen-related receptor gamma is an in vivo receptor of bisphenol A. FASEB J (2014) 28:3124-33. doi:10.1096/fj.13-240465
    • (2014) FASEB J , vol.28 , pp. 3124-3133
    • Tohme, M.1    Prud'homme, S.M.2    Boulahtouf, A.3    Samarut, E.4    Brunet, F.5    Bernard, L.6
  • 155
    • 33751005817 scopus 로고    scopus 로고
    • Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity
    • Takayanagi S, Tokunaga T, Liu X, Okada H, Matsushima A, Shimohigashi Y. Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity. Toxicol Lett (2006) 167:95-105. doi:10.1016/j.toxlet.2006.08.012
    • (2006) Toxicol Lett , vol.167 , pp. 95-105
    • Takayanagi, S.1    Tokunaga, T.2    Liu, X.3    Okada, H.4    Matsushima, A.5    Shimohigashi, Y.6
  • 156
    • 84891445363 scopus 로고    scopus 로고
    • Nuclear receptor profiling of bisphenol-A and its halogenated analogues
    • Delfosse V, Grimaldi M, Le Maire A, Bourguet W, Balaguer P. Nuclear receptor profiling of bisphenol-A and its halogenated analogues. Vitam Horm (2014) 94:229-51. doi:10.1016/B978-0-12-800095-3.00009-2
    • (2014) Vitam Horm , vol.94 , pp. 229-251
    • Delfosse, V.1    Grimaldi, M.2    Le Maire, A.3    Bourguet, W.4    Balaguer, P.5
  • 157
    • 33646133406 scopus 로고    scopus 로고
    • The expanding cosmos of nuclear receptor coactivators
    • Lonard DM, O'Malley BW. The expanding cosmos of nuclear receptor coactivators. Cell (2006) 125:411-4. doi:10.1016/j.cell.2006.04.021
    • (2006) Cell , vol.125 , pp. 411-414
    • Lonard, D.M.1    O'Malley, B.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.