Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats

Toxicology

Volumn 250, Issue 2-3, 2008, Pages 75-81

  Boberg, Julie ^a   Metzdorff, Stine ^a   Wortziger, Rasmus ^a   Axelstad, Marta ^a   Brokken, Leon ^b   Vinggaard, Anne Marie ^a   Dalgaard, Majken ^a   Nellemann, Christine ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

Diisobutyl phthalate; Insulin; Leptin; Paraben; Perfluorooctaonate; Prenatal; Rat; Rosiglitazone; Steroidogenesis; Testis

Indexed keywords

AROMATASE; BUTYL PARABEN; DIISOBUTYLPHTHALATE; ENDOCRINE DISRUPTOR; INSULIN; INSULIN LIKE FACTOR 3; LEPTIN; MESSENGER RNA; PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHTHALIC ACID; PROTEIN; ROSIGLITAZONE; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FETOTOXICITY; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION; GESTATIONAL AGE; HORMONE BLOOD LEVEL; INSULIN BLOOD LEVEL; LIVER; MALE; METABOLISM; NONHUMAN; OVARY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; RAT; STEROIDOGENESIS; TESTIS; TESTOSTERONE SYNTHESIS; TISSUE DISTRIBUTION; VIRILIZATION;

ADRENAL GLANDS; ANIMALS; BODY WEIGHT; DIBUTYL PHTHALATE; ESTRADIOL; FEMALE; FETUS; GENE EXPRESSION; GESTATIONAL AGE; IMMUNOHISTOCHEMISTRY; INSULIN; LEPTIN; LIVER; MALE; OVARY; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PPAR ALPHA; PPAR GAMMA; PREGNANCY; RATS; RATS, WISTAR; RNA, MESSENGER; STEROIDS; TESTIS; TESTOSTERONE;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 49849083537     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.05.020     Document Type: Article

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