Blockage of TGFβ-SMAD2 by demethylation-activated miR-148a is involved in caffeic acid-induced inhibition of cancer stem cell-like properties in vitro and in vivo

FEBS Open Bio

Volumn 5, Issue , 2015, Pages 466-475

  Li, Yuan ^a   Jiang, Fei ^a   Chen, Lijun ^a   Yang, Ye ^a   Cao, Shuyuan ^a   Ye, Yuting ^a   Wang, Xingxing ^a   Mu, Juan ^a   Li, Zhong ^a   Li, Lei ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Caffeic acid; Cancer stem cells like properties; DNA methylation; MicroRNA 148a; Transforming growth factor beta SMAD2 signal pathway

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; ANTINEOPLASTIC AGENT; BMI1 PROTEIN; CAFFEIC ACID; CELL SURFACE MARKER; DNA METHYLTRANSFERASE 1; EPITHELIAL CELL ADHESION MOLECULE; MESSENGER RNA; MICRORNA; MICRORNA 148A; MICRORNA 155; OCTAMER TRANSCRIPTION FACTOR 4; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER STEM CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DOWN REGULATION; DRUG TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR VOLUME;

EID: 84930943636     PISSN: 22115463     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fob.2015.05.009     Document Type: Article

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