Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells

International Journal of Biochemistry and Cell Biology

Volumn 65, Issue , 2015, Pages 125-133

  Smolková, Katarína ^a   Dvořák, Aleš ^a,b   Zelenka, Jaroslav ^a   Vítek, Libor ^b   Ježek, Petr ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Breast adenocarcinoma MDA MB 231 cells; Breast carcinoma HTB 126 cells; Hypoxia; NADPH dependent isocitrate dehydrogenase IDH2; Oncometabolite r 2 hydroxyglutarate; Reductive carboxylation

Indexed keywords

2 HYDROXYGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; CARBON 13; CARBON DIOXIDE; CITRIC ACID; GLUCOSE; GLUTAMINE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; MALIC ACID; ALPHA-HYDROXYGLUTARATE; GLUTARIC ACID DERIVATIVE; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 2, HUMAN; OXYGEN; TUMOR MARKER;

ARTICLE; BREAST CARCINOMA; CARBOXYLATION; CARCINOMA CELL; CELL HYPOXIA; CELL RESPIRATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OXYGEN TENSION; PROTEIN EXPRESSION; BREAST TUMOR; ENZYMOLOGY; FEMALE; GENETICS; METABOLISM; PARTIAL PRESSURE; PHYSIOLOGY; TUMOR CELL LINE;

BIOMARKERS, TUMOR; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; FEMALE; GLUTARATES; HUMANS; ISOCITRATE DEHYDROGENASE; OXYGEN; PARTIAL PRESSURE;

EID: 84930938063     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2015.05.012     Document Type: Article

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