Long-term high-fat high-sucrose diet promotes enlarged islets and β-cell damage by oxidative stress in bama minipigs

Pancreas

Volumn 44, Issue 6, 2015, Pages 888-895

  Zhao, Zhan Zhao ^a,b   Xin, Lei Lei ^a   Xia, Ji Han ^a   Yang, Shu Lin ^a   Chen, Yao Xing ^b   Li, Kui ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

apoptosis; Bama minipigs; oxidative stress; pancreas; steatosis

Indexed keywords

CASPASE 3; CYCLINE; GLUCOSE; GLUCOSE OXIDASE; GLYCOGEN; INSULIN; PROTEIN BAX; ANTIOXIDANT; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; MALONALDEHYDE; PROTEIN BCL 2; SUGAR INTAKE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; BAMA MINIATURE PIG; BIOCHEMICAL ANALYSIS; BODY WEIGHT; CELL ACTIVATION; CELL DAMAGE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DIET THERAPY; ENZYME ACTIVITY; FATTY LIVER; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HIGH FAT HIGH SUCROSE DIET; HISTOPATHOLOGY; HYPERINSULINEMIA; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; INSULIN RESISTANCE; INTRAVENOUS GLUCOSE TOLERANCE TEST; LIPID PEROXIDATION; LIPID STORAGE; LONG TERM CARE; NONHUMAN; OBESITY; OXIDATION; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PANCREATIC STEATOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; STEATOSIS; TISSUE STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; BLOOD; DISEASE MODEL; HYPERINSULINISM; LIPID DIET; METABOLISM; MINIPIG; PANCREAS ISLET; PANCREATIC DISEASES; PATHOLOGY; PIG; SUGAR INTAKE; TIME FACTOR; ULTRASTRUCTURE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIOMARKERS; BLOOD GLUCOSE; CASPASE 3; CELL PROLIFERATION; DIET, HIGH-FAT; DIETARY SUCROSE; DISEASE MODELS, ANIMAL; GLYCOGEN; HYPERINSULINISM; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; LIPID PEROXIDATION; MALONDIALDEHYDE; OBESITY; OXIDATIVE STRESS; PANCREATIC DISEASES; PROTO-ONCOGENE PROTEINS C-BCL-2; SWINE; SWINE, MINIATURE; TIME FACTORS;

EID: 84930930137     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0000000000000349     Document Type: Article

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