Autophagy sustains the survival of human pancreatic cancer PANC-1 cells under extreme nutrient deprivation conditions

Biochemical and Biophysical Research Communications

Volumn 463, Issue 3, 2015, Pages 205-210

  Kim, Sang Eun ^a   Park, Hye Jin ^a   Jeong, Hye Kyoung ^a   Kim, Mi Jung ^a   Kim, Minyeong ^a   Bae, Ok Nam ^b   Baek, Seung Hoon ^a  

^a Ajou University   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Apoptosis; Autophagy; Extreme nutrient deprivation; PANC 1; Survival

Indexed keywords

ADENYLATE KINASE; AMINO ACID; AUTOPHAGY PROTEIN 5; BECLIN 1; BETA TUBULIN; CASPASE 3; CELL PROTEIN; CHLOROQUINE; GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GREEN FLUORESCENT PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; PROTEIN LC3 II; S6 KINASE; UNCLASSIFIED DRUG; WORTMANNIN; ANDROSTANE DERIVATIVE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PEPTIDE CHLOROMETHYL KETONE; TARGET OF RAPAMYCIN KINASE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LYSOSOME; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; NUTRIENT; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SOLID TUMOR; TUMOR MICROENVIRONMENT; DRUG EFFECTS; METABOLISM; PANCREAS; PANCREATIC NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

AMINO ACID CHLOROMETHYL KETONES; AMINO ACIDS; AMP-ACTIVATED PROTEIN KINASES; ANDROSTADIENES; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; CHLOROQUINE; GLUCOSE; HUMANS; PANCREAS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; TOR SERINE-THREONINE KINASES;

EID: 84930926354     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.05.022     Document Type: Article

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