Homo- and hetero-dimerization of human UDP-glucuronosyltransferase 2B7 (UGT2B7) wild type and its allelic variants affect zidovudine glucuronidation activity

Biochemical Pharmacology

Volumn 95, Issue 1, 2015, Pages 58-70

  Yuan, Lingmin ^a   Qian, Sainan ^a   Xiao, Yongsheng ^a   Sun, Hongying ^a   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Dimerization; FRET; nsSNPs; UGT2B7; Zidovudine

Indexed keywords

GLUCURONIDE; GLUCURONOSYLTRANSFERASE; UGT2B7 PROTEIN, HUMAN; ZIDOVUDINE;

ALLELE; ANIMAL; CELL LINE; DIMERIZATION; DRUG EFFECTS; GENETIC VARIABILITY; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; SF9 CELL LINE; SPODOPTERA;

ALLELES; ANIMALS; CELL LINE; DIMERIZATION; GENETIC VARIATION; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; SF9 CELLS; SPODOPTERA; ZIDOVUDINE;

EID: 84930921828     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.03.002     Document Type: Article

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