Quantitative regioselectivity of glucuronidation of quercetin by recombinant UDP-glucuronosyltransferases 1A9 and 1A3 using enzymatic kinetic parameters

Xenobiotica

Volumn 35, Issue 10-11, 2005, Pages 943-954

  Chen, Y K ^a   Chen, S Q ^a   Li, X ^a   Zeng, S ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Bac to Bac; Glucuronidation; Quercetin; Regioselectivity; UGT1A3; UGT1A9

Indexed keywords

DRUG METABOLITE; GLUCURONIDE; QUERCETIN; QUERCETIN 3 GLUCURONIDE; QUERCETIN 3' GLUCURONIDE; QUERCETIN 4' GLUCURONIDE; QUERCETIN 7 GLUCURONIDE; RECOMBINANT ENZYME; RECOMBINANT UDP GLUCURONOSYLTRANSFERASE 1A3; RECOMBINANT UDP GLUCURONOSYLTRANSFERASE 1A9; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; DRUG GLUCURONIDATION; DRUG METABOLISM; ENZYME KINETICS; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS;

COMPUTER SIMULATION; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; ISOMERISM; KINETICS; MODELS, CHEMICAL; PROTEIN ENGINEERING; QUERCETIN; RECOMBINANT PROTEINS;

EID: 30344456999     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250500372172     Document Type: Article

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