Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen

Biochemical Pharmacology

Volumn 82, Issue 11, 2011, Pages 1757-1763

  Wang, Haina ^a,b   Yuan, Lingmin ^a   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Flurbiprofen; Single nucleotide polymorphism; Stereoselectivity; UGT1A9; UGT2B7

Indexed keywords

ALLOENZYME; FLURBIPROFEN; GLUCURONIDE; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2B7;

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CATALYSIS; CLEARANCE; CONTROLLED STUDY; ENANTIOSELECTIVITY; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC VARIABILITY; GLUCURONIDATION; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STEREOCHEMISTRY; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FLURBIPROFEN; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; STEREOISOMERISM;

EID: 80255122759     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.08.004     Document Type: Article

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