-
1
-
-
0042858402
-
Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyitransferase 2B4 enzyme
-
Barbier O, Duran-Sandoval D, Pineda-Torra I, Kosykh V, Fruchart JC, and Staels B (2003a) Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP- glucuronosyitransferase 2B4 enzyme. J Biol Chem 278:32852-32860.
-
(2003)
J Biol Chem
, vol.278
, pp. 32852-32860
-
-
Barbier, O.1
Duran-Sandoval, D.2
Pineda-Torra, I.3
Kosykh, V.4
Fruchart, J.C.5
Staels, B.6
-
2
-
-
0038281429
-
FXR induces the UGT2B4 enzyme in hepatocytes: A potential mechanism of negative feedback control of FXR activity
-
Barbier O, Torra IP, Sirvent A, Claudel T, Blanquart C, Duran-Sandoval D, Kuipers F, Kosykh V, Fruchart JC, and Staels B (2003b) FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity. Gastroenterology 124:1926-1940.
-
(2003)
Gastroenterology
, vol.124
, pp. 1926-1940
-
-
Barbier, O.1
Torra, I.P.2
Sirvent, A.3
Claudel, T.4
Blanquart, C.5
Duran-Sandoval, D.6
Kuipers, F.7
Kosykh, V.8
Fruchart, J.C.9
Staels, B.10
-
3
-
-
0029809062
-
Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids
-
Beaulieu M, Lévesque E, Hum DW, and Bélanger A (1996) Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids. J Biol Chem 271:22855-22862.
-
(1996)
J Biol Chem
, vol.271
, pp. 22855-22862
-
-
Beaulieu, M.1
Lévesque, E.2
Hum, D.W.3
Bélanger, A.4
-
4
-
-
0344784391
-
Isolation and characterization of a human orphan UDP- glucuronosyltransferase, UGT2B11
-
Beaulieu M, Lévesque E, Hum DW, and Bélanger A (1998) Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11. Biochem Biophys Res Commun 248:44-50.
-
(1998)
Biochem Biophys Res Commun
, vol.248
, pp. 44-50
-
-
Beaulieu, M.1
Lévesque, E.2
Hum, D.W.3
Bélanger, A.4
-
5
-
-
0033645752
-
Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: Ethnic diversity of alleles and potential clinical significance
-
Bhasker CR, McKinnon W, Stone A, Lo AC, Kubota T, Ishizaki T, and Miners JO (2000) Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance. Pharmacogenetics 10:679-685.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 679-685
-
-
Bhasker, C.R.1
McKinnon, W.2
Stone, A.3
Lo, A.C.4
Kubota, T.5
Ishizaki, T.6
Miners, J.O.7
-
6
-
-
0034616660
-
Isolation and characterization of the human UGT2B7 gene
-
Carrier JS, Turgeon D, Journault K, Hum DW, and Belanger A (2000) Isolation and characterization of the human UGT2B7 gene. Biochem Biophys Res Commun 272:616-621.
-
(2000)
Biochem Biophys Res Commun
, vol.272
, pp. 616-621
-
-
Carrier, J.S.1
Turgeon, D.2
Journault, K.3
Hum, D.W.4
Belanger, A.5
-
8
-
-
0042858542
-
Evaluation of 3′-azido-3′-deoxythymidine, morphine and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: Specificity and influence of the UGT2B7*2 polymorphism
-
Court MH, Krishnaswamy S, Hao Q, Duan SX, Patten CJ, Von Moltke LL, and Greenblatt DJ (2003) Evaluation of 3′-azido-3′-deoxythymidine, morphine and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism. Drug Metab Dispos 31:1125-1133.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1125-1133
-
-
Court, M.H.1
Krishnaswamy, S.2
Hao, Q.3
Duan, S.X.4
Patten, C.J.5
Von Moltke, L.L.6
Greenblatt, D.J.7
-
9
-
-
0033661491
-
Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: Relationship between UGTIAI promoter genotype and variability in a liver bank
-
Fisher MB, VandenBranden M, Findlay K, Burchell B, Thummel KE, Hall SD, and Wrighton SA (2000) Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGTIAI promoter genotype and variability in a liver bank. Pharmacogenetics 10:727-739.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 727-739
-
-
Fisher, M.B.1
VandenBranden, M.2
Findlay, K.3
Burchell, B.4
Thummel, K.E.5
Hall, S.D.6
Wrighton, S.A.7
-
10
-
-
0344950514
-
Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy
-
Hirota T, Ieiri I, Takane H, Sano H, Kawamoto K, Aono H, Yamasaki A, Takeuchi H, Masada M, Shimizu E, et al. (2003) Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy. Drug Metab Dispos 31:677-680.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 677-680
-
-
Hirota, T.1
Ieiri, I.2
Takane, H.3
Sano, H.4
Kawamoto, K.5
Aono, H.6
Yamasaki, A.7
Takeuchi, H.8
Masada, M.9
Shimizu, E.10
-
11
-
-
0036373740
-
Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy
-
Holthe M, Klepstad P, Zahlsen K, Borchgrevink PC, Hagen L, Dale O, Kaasa S, Krokan HE, and Skorpen F (2002) Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy. Eur J Clin Pharmacol 58:353-356.
-
(2002)
Eur J Clin Pharmacol
, vol.58
, pp. 353-356
-
-
Holthe, M.1
Klepstad, P.2
Zahlsen, K.3
Borchgrevink, P.C.4
Hagen, L.5
Dale, O.6
Kaasa, S.7
Krokan, H.E.8
Skorpen, F.9
-
12
-
-
0037251316
-
Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: Identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients
-
Holthe M, Rakvag TN, Klepstad P, Idle JR, Kaasa S, Krokan HE, and Skorpen F (2003) Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients. Pharmacogenomics J 3:17-26.
-
(2003)
Pharmacogenomics J
, vol.3
, pp. 17-26
-
-
Holthe, M.1
Rakvag, T.N.2
Klepstad, P.3
Idle, J.R.4
Kaasa, S.5
Krokan, H.E.6
Skorpen, F.7
-
13
-
-
0037159194
-
Activation of glucuronidation through reduction of a disulfide bond in rat UDP-glucuronosyltransferase 1A6
-
Ikushiro S, Emi Y, and Iyanagi T (2002) Activation of glucuronidation through reduction of a disulfide bond in rat UDP-glucuronosyltransferase 1A6. Biochemistry 41:12813-12820.
-
(2002)
Biochemistry
, vol.41
, pp. 12813-12820
-
-
Ikushiro, S.1
Emi, Y.2
Iyanagi, T.3
-
14
-
-
0034057412
-
Octamer transcription factor-1 enhances hepatic nuclear factor-1α-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter
-
Ishii Y, Hansen AJ, and Mackenzie PI (2000) Octamer transcription factor-1 enhances hepatic nuclear factor-1α-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter. Mol Pharmacol 57:940-947.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 940-947
-
-
Ishii, Y.1
Hansen, A.J.2
Mackenzie, P.I.3
-
15
-
-
0023126361
-
Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA
-
Jackson MR, McCarthy LR, Harding D, Wilson S, Coughtrie MW, and Burchell B (1987) Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA. Biochem J 242:581-588.
-
(1987)
Biochem J
, vol.242
, pp. 581-588
-
-
Jackson, M.R.1
McCarthy, L.R.2
Harding, D.3
Wilson, S.4
Coughtrie, M.W.5
Burchell, B.6
-
16
-
-
0027267719
-
cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily
-
Jin CJ, Miners JO, Lillywhite KJ, and Mackenzie PI (1993) cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily. Biochem Biophys Res Commun 194:496-503.
-
(1993)
Biochem Biophys Res Commun
, vol.194
, pp. 496-503
-
-
Jin, C.J.1
Miners, J.O.2
Lillywhite, K.J.3
Mackenzie, P.I.4
-
17
-
-
0036562879
-
Determination of probability distribution of diplotype configuration (diplotype distribution) for each subject from genotypic data using the EM algorithm
-
Kitamura Y, Moriguchi M, Kaneko H, Morisaki H, Morisaki T, Toyama K, and Kamatani N (2002) Determination of probability distribution of diplotype configuration (diplotype distribution) for each subject from genotypic data using the EM algorithm. Ann Hum Genet 66:183-193.
-
(2002)
Ann Hum Genet
, vol.66
, pp. 183-193
-
-
Kitamura, Y.1
Moriguchi, M.2
Kaneko, H.3
Morisaki, H.4
Morisaki, T.5
Toyama, K.6
Kamatani, N.7
-
18
-
-
0034118356
-
Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4(D458E), UGT2B7(H268Y) and UGT2B15(D85Y)
-
Lampe JW, Bigler J, Bush AC, and Potter JD (2000) Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4(D458E), UGT2B7(H268Y) and UGT2B15(D85Y). Cancer Epidemiol Biomarkers Prev 9:329-333.
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 329-333
-
-
Lampe, J.W.1
Bigler, J.2
Bush, A.C.3
Potter, J.D.4
-
19
-
-
0032812606
-
Characterization and substrate specificity of UGT2B4(E458): A UDP-glucuronosyltransferase encoded by a polymorphic gene
-
Lévesque E, Beaulieu M, Hum DW and Bélanger A (1999) Characterization and substrate specificity of UGT2B4(E458): a UDP-glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics 9:207-216.
-
(1999)
Pharmacogenetics
, vol.9
, pp. 207-216
-
-
Lévesque, E.1
Beaulieu, M.2
Hum, D.W.3
Bélanger, A.4
-
20
-
-
0035799361
-
Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase
-
Lévesque E, Turgeon D, Carrier J-S, Montminy V, Beaulieu M, and Bélanger A (2001) Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase. Biochemistry 40:3869-3881.
-
(2001)
Biochemistry
, vol.40
, pp. 3869-3881
-
-
Lévesque, E.1
Turgeon, D.2
Carrier, J.-S.3
Montminy, V.4
Beaulieu, M.5
Bélanger, A.6
-
21
-
-
0037298816
-
Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7
-
Mackenzie P, Little JM, and Radominska-Pandya A (2003) Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. Biochem Pharmacol 65:417-421.
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 417-421
-
-
Mackenzie, P.1
Little, J.M.2
Radominska-Pandya, A.3
-
22
-
-
8544224973
-
The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
-
Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Belanger A, Foumel-Gigleux S, Green M, Hum DW, Iyanagi T, et al. (1997) The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7:255-269.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 255-269
-
-
Mackenzie, P.I.1
Owens, I.S.2
Burchell, B.3
Bock, K.W.4
Bairoch, A.5
Belanger, A.6
Foumel-Gigleux, S.7
Green, M.8
Hum, D.W.9
Iyanagi, T.10
-
23
-
-
0029956992
-
Mutational analysis of the carboxy-terminal region of UDP-glucuronosyltransferase 2B1
-
Meech R, Yogalingam G, and Mackenzie PI (1996) Mutational analysis of the carboxy-terminal region of UDP-glucuronosyltransferase 2B1. DNA Cell Biol 15:489-494.
-
(1996)
DNA Cell Biol
, vol.15
, pp. 489-494
-
-
Meech, R.1
Yogalingam, G.2
Mackenzie, P.I.3
-
24
-
-
0028136583
-
Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13
-
Monaghan G, Clarke DJ, Povey S, See CG, Boxer M, and Burchell B (1994) Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13. Genomics 23:496-499.
-
(1994)
Genomics
, vol.23
, pp. 496-499
-
-
Monaghan, G.1
Clarke, D.J.2
Povey, S.3
See, C.G.4
Boxer, M.5
Burchell, B.6
-
25
-
-
0842304214
-
Involvement of human hepatic UGT1A1, UGT2B4, and UGT2B7 in the glucuronidation of carvedilol
-
Ohno A, Saito Y, Hanioka N, Jinno H, Saeki M, Ando M, Ozawa S, and Sawada J (2004) Involvement of human hepatic UGT1A1, UGT2B4, and UGT2B7 in the glucuronidation of carvedilol. Drug Metab Dispos 32:235-239.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 235-239
-
-
Ohno, A.1
Saito, Y.2
Hanioka, N.3
Jinno, H.4
Saeki, M.5
Ando, M.6
Ozawa, S.7
Sawada, J.8
-
26
-
-
0027431814
-
Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4
-
Pillot T, Ouzzine M, Foumel-Gigleux S, Lafaurie C, Radominska A, Burchell B, Siest G, and Magdalou J (1993) Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4. J Biol Chem 268:25636-25642.
-
(1993)
J Biol Chem
, vol.268
, pp. 25636-25642
-
-
Pillot, T.1
Ouzzine, M.2
Foumel-Gigleux, S.3
Lafaurie, C.4
Radominska, A.5
Burchell, B.6
Siest, G.7
Magdalou, J.8
-
27
-
-
0032707765
-
Structural and functional studies of UDP-glucuronosyltransferases
-
Radominska-Pandya A, Czernik PJ, and Little JM (1999) Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev 31:817-899.
-
(1999)
Drug Metab Rev
, vol.31
, pp. 817-899
-
-
Radominska-Pandya, A.1
Czernik, P.J.2
Little, J.M.3
-
28
-
-
0034050743
-
Genomic organization of the UGT2b gene cluster on human chromosome 4q13
-
Riedy M, Wang JY, Miller AP, Buckler A, Hall J, and Guida M (2000) Genomic organization of the UGT2b gene cluster on human chromosome 4q13. Pharmacogenetics 10:251-260.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 251-260
-
-
Riedy, M.1
Wang, J.Y.2
Miller, A.P.3
Buckler, A.4
Hall, J.5
Guida, M.6
-
29
-
-
0025321169
-
Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells: 3,4-catechol estrogens and estriol as primary substrates
-
Ritter JK, Sheen YY, and Owens IS (1990) Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells: 3,4-catechol estrogens and estriol as primary substrates. J Biol Chem 265:7900-7906.
-
(1990)
J Biol Chem
, vol.265
, pp. 7900-7906
-
-
Ritter, J.K.1
Sheen, Y.Y.2
Owens, I.S.3
-
30
-
-
0038209379
-
A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine
-
Sawyer MB, Innocenti F, Das S, Cheng C, Ramirez J, Pantle-Fisher FH, Wright C, Badner J, Pei D, Boyett JM, et al. (2003) A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. Clin Pharmacol Ther 73:566-574.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 566-574
-
-
Sawyer, M.B.1
Innocenti, F.2
Das, S.3
Cheng, C.4
Ramirez, J.5
Pantle-Fisher, F.H.6
Wright, C.7
Badner, J.8
Pei, D.9
Boyett, J.M.10
-
31
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression and disease
-
Tukey RH and Strassburg CP (2000) Human UDP-glucuronosyltransferases: metabolism, expression and disease. Annu Rev Pharmacol Toxicol 40:581-616.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
32
-
-
0034695410
-
Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4
-
Turgeon D, Carrier J-S, Lévesque E, Beatty BG, Bélanger A, and Hum DW (2000) Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4. J Mol Biol 295:489-504.
-
(2000)
J Mol Biol
, vol.295
, pp. 489-504
-
-
Turgeon, D.1
Carrier, J.-S.2
Lévesque, E.3
Beatty, B.G.4
Bélanger, A.5
Hum, D.W.6
-
33
-
-
0035103197
-
Relative enzymatic activity, protein stability and tissue distribution of human steroid-metabolizing UGT2B subfamily members
-
Turgeon D, Carrier JS, Levesque E, Hum DW, and Belanger A (2001) Relative enzymatic activity, protein stability and tissue distribution of human steroid-metabolizing UGT2B subfamily members. Endocrinology 142:778-787.
-
(2001)
Endocrinology
, vol.142
, pp. 778-787
-
-
Turgeon, D.1
Carrier, J.S.2
Levesque, E.3
Hum, D.W.4
Belanger, A.5
|