-
1
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. 2011 Hallmarks of cancer: the next generation. Cell 144, 646–674. (doi:10.1016/j.cell.2011.02.013).
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
84907737648
-
Genome sequencing of normal cells reveals developmental lineages and mutational processes
-
Behjati S et al. 2014 Genome sequencing of normal cells reveals developmental lineages and mutational processes. Nature 513, 422–425. (doi:10.1038/nature13448).
-
(2014)
Nature
, vol.513
, pp. 422-425
-
-
Behjati, S.1
-
3
-
-
84856411877
-
Decoding cell lineage from acquired mutations using arbitrary deep sequencing. Nat
-
Carlson CA, Kas A, Kirkwood R, Hays LE, Preston BD, Salipante SJ, Horwitz MS. 2012 Decoding cell lineage from acquired mutations using arbitrary deep sequencing. Nat. Methods 9, 78–80. (doi:10.1038/nmeth.1781).
-
(2012)
Methods
, vol.9
, pp. 78-80
-
-
Carlson, C.A.1
Kas, A.2
Kirkwood, R.3
Hays, L.E.4
Preston, B.D.5
Salipante, S.J.6
Horwitz, M.S.7
-
4
-
-
84888230291
-
Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations. PLoS Comput
-
1003297
-
Chapal-Ilani N, Maruvka YE, Spiro A, Reizel Y, Adar R, Shlush LI, Shapiro E. 2013 Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations. PLoS Comput. Biol. 9, e1003297. (doi:10.1371/journal.pcbi.1003297).
-
(2013)
Biol
, pp. 9
-
-
Chapal-Ilani, N.1
Maruvka, Y.E.2
Spiro, A.3
Reizel, Y.4
Adar, R.5
Shlush, L.I.6
Shapiro, E.7
-
5
-
-
84872291407
-
Use of somatic mutations to quantify random contributions to mouse development
-
Zhou W, Tan Y, Anderson DJ, Crist EM, Ruohola-Baker H, Salipante SJ, Horwitz MS. 2013 Use of somatic mutations to quantify random contributions to mouse development. BMC Genomics 14, 39. (doi:10.1186/1471-2164-14-39).
-
(2013)
BMC Genomics
, vol.14
, pp. 39
-
-
Zhou, W.1
Tan, Y.2
Erson, D.J.3
Crist, E.M.4
Ruohola-Baker, H.5
Salipante, S.J.6
Horwitz, M.S.7
-
6
-
-
79952579323
-
Peto’s paradox: Evolution’s prescription for cancer prevention. Trends Ecol
-
Caulin AF, Maley CC. 2011 Peto’s paradox: evolution’s prescription for cancer prevention. Trends Ecol. Evol. 26, 175–182. (doi:10.1016/j.tree.2011.01.002).
-
(2011)
Evol
, vol.26
, pp. 175-182
-
-
Caulin, A.F.1
Maley, C.C.2
-
7
-
-
84893449856
-
Oxford and the Savannah: Can the hippo provide an explanation for Peto’s paradox? Clin
-
Kelleher FC, O’Sullivan H. 2014 Oxford and the Savannah: can the hippo provide an explanation for Peto’s paradox? Clin. Cancer Res. 20, 557–564. (doi:10.1158/1078-0432.CCR-13-2010).
-
(2014)
Cancer Res
, vol.20
, pp. 557-564
-
-
Kelleher, F.C.1
O’Sullivan, H.2
-
8
-
-
34547824644
-
Why don’t all whales have cancer? A novel hypothesis resolving Peto’s paradox. Integr. Comp
-
Nagy JD, Victor EM, Cropper JH. 2007 Why don’t all whales have cancer? A novel hypothesis resolving Peto’s paradox. Integr. Comp. Biol. 47, 317–328. (doi:10.1093/icb/icm062).
-
(2007)
Biol
, vol.47
, pp. 317-328
-
-
Nagy, J.D.1
Victor, E.M.2
Cropper, J.H.3
-
9
-
-
84872798905
-
Peto’s paradox revisited: Theoretical evolutionary dynamics of cancer in wild populations. Evol
-
Roche B, Sprouffske K, Hbid H, Misse D, Thomas F. 2013 Peto’s paradox revisited: theoretical evolutionary dynamics of cancer in wild populations. Evol. Appl. 6, 109–116. (doi:10.1111/eva.12025).
-
(2013)
Appl
, vol.6
, pp. 109-116
-
-
Roche, B.1
Sprouffske, K.2
Hbid, H.3
Misse, D.4
Thomas, F.5
-
10
-
-
84860512005
-
Links between metabolism and cancer
-
Dang CV. 2012 Links between metabolism and cancer. Genes Dev. 26, 877–890. (doi:10.1101/gad.189365.112).
-
(2012)
Genes Dev
, vol.26
, pp. 877-890
-
-
Dang, C.V.1
-
11
-
-
0004146634
-
-
Cambridge, UK: Cambridge University Press
-
Schrodinger E. 1944 What is life? Cambridge, UK: Cambridge University Press.
-
(1944)
What is Life?
-
-
Schrodinger, E.1
-
12
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. 2009 Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029–1033. (doi:10.1126/science.1160809).
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
13
-
-
84868019043
-
Cancer cell metabolism: One hallmark, many faces
-
Cantor JR, Sabatini DM. 2012 Cancer cell metabolism: one hallmark, many faces. Cancer Discov. 2, 881–898. (doi:10.1158/2159-8290.CD-12-0345).
-
(2012)
Cancer Discov
, vol.2
, pp. 881-898
-
-
Cantor, J.R.1
Sabatini, D.M.2
-
14
-
-
0028802746
-
A hierarchy of ATPconsuming processes in mammalian cells
-
Buttgereit F, Brand MD. 1995 A hierarchy of ATPconsuming processes in mammalian cells. Biochem. J. 312, 163–167.
-
(1995)
Biochem. J
, vol.312
, pp. 163-167
-
-
Buttgereit, F.1
Brand, M.D.2
-
15
-
-
0030854715
-
Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol
-
Rolfe DF, Brown GC. 1997 Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol. Rev. 77, 731–758.
-
(1997)
Rev
, vol.77
, pp. 731-758
-
-
Rolfe, D.F.1
Brown, G.C.2
-
18
-
-
84890209181
-
Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Mol. Syst
-
Fan J, Kamphorst JJ, Mathew R, Chung MK, White E, Shlomi T, Rabinowitz JD. 2013 Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Mol. Syst. Biol. 9, 712. (doi:10.1038/msb.2013.65).
-
(2013)
Biol
, vol.9
, pp. 712
-
-
Fan, J.1
Kamphorst, J.J.2
Mathew, R.3
Chung, M.K.4
White, E.5
Shlomi, T.6
Rabinowitz, J.D.7
-
19
-
-
79955764625
-
Glutamine: Pleiotropic roles in tumor growth and stress resistance
-
Shanware NP, Mullen AR, DeBerardinis RJ, Abraham RT. 2011 Glutamine: pleiotropic roles in tumor growth and stress resistance. J. Mol. Med. 89, 229–236. (doi:10.1007/s00109-011-0731-9).
-
(2011)
J. Mol. Med
, vol.89
, pp. 229-236
-
-
Shanware, N.P.1
Mullen, A.R.2
Deberardinis, R.J.3
Abraham, R.T.4
-
20
-
-
0022196860
-
Glutamine metabolism in lymphocytes: Its biochemical, physiological and clinical importance
-
Newsholme EA, Crabtree B, Ardawi MS. 1985 Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance. Q. J. Exp. Physiol. 70, 473–489. (doi:10.1113/expphysiol.1985.sp002935).
-
(1985)
Q. J. Exp. Physiol
, vol.70
, pp. 473-489
-
-
Newsholme, E.A.1
Crabtree, B.2
Ardawi, M.S.3
-
21
-
-
84883497454
-
Glutamine and cancer: Cell biology, physiology, and clinical opportunities
-
Hensley CT, Wasti AT, DeBerardinis RJ. 2013 Glutamine and cancer: cell biology, physiology, and clinical opportunities. J. Clin. Investig. 123, 3678–3684. (doi:10.1172/JCI69600).
-
(2013)
J. Clin. Investig
, vol.123
, pp. 3678-3684
-
-
Hensley, C.T.1
Wasti, A.T.2
Deberardinis, R.J.3
-
22
-
-
84859778293
-
Sabatini DM. 2012 mTOR signaling in growth control and disease
-
Laplante M, Sabatini DM. 2012 mTOR signaling in growth control and disease. Cell 149, 274–293. (doi:10.1016/j.cell.2012.03.017).
-
Cell 149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
23
-
-
84859171807
-
MYC on the path to cancer
-
Dang CV. 2012 MYC on the path to cancer. Cell 149, 22–35. (doi:10.1016/j.cell.2012.03.003).
-
(2012)
Cell
, vol.149
, pp. 22-35
-
-
Dang, C.V.1
-
25
-
-
84883182637
-
Disrupting proton dynamics and energy metabolism for cancer therapy. Nat
-
Parks SK, Chiche J, Pouyssegur J. 2013 Disrupting proton dynamics and energy metabolism for cancer therapy. Nat. Rev. Cancer 13, 611–623. (doi:10.1038/nrc3579).
-
(2013)
Rev. Cancer
, vol.13
, pp. 611-623
-
-
Parks, S.K.1
Chiche, J.2
Pouyssegur, J.3
-
26
-
-
77953935500
-
Tumour hypoxia induces a metabolic shift causing acidosis: A common feature in cancer
-
Chiche J, Brahimi-Horn MC, Pouyssegur J. 2010 Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer. J. Cell. Mol. Med. 14, 771–794. (doi:10.1111/j.1582-4934.2009.00994.x).
-
(2010)
J. Cell. Mol. Med
, vol.14
, pp. 771-794
-
-
Chiche, J.1
Brahimi-Horn, M.C.2
Pouyssegur, J.3
-
27
-
-
35248828654
-
Hypoxia in cancer cell metabolism and pH regulation
-
Brahimi-Horn MC, Pouyssegur J. 2007 Hypoxia in cancer cell metabolism and pH regulation. Essays Biochem. 43, 165–178. (doi:10.1042/BSE0430165).
-
(2007)
Essays Biochem
, vol.43
, pp. 165-178
-
-
Brahimi-Horn, M.C.1
Pouyssegur, J.2
-
28
-
-
84902965305
-
Role of the Keap1-Nrf2 pathway in cancer. Adv
-
Leinonen HM, Kansanen E, Polonen P, Heinaniemi M, Levonen AL. 2014 Role of the Keap1-Nrf2 pathway in cancer. Adv. Cancer Res. 122, 281–320. (doi:10.1016/B978-0-12-420117-0.00008-6).
-
(2014)
Cancer Res
, vol.122
, pp. 281-320
-
-
Leinonen, H.M.1
Kansanen, E.2
Polonen, P.3
Heinaniemi, M.4
Levonen, A.L.5
-
29
-
-
84885944468
-
The emerging role of the Nrf2-Keap1 signaling pathway in cancer
-
Jaramillo MC, Zhang DD. 2013 The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes Dev. 27, 2179–2191. (doi:10.1101/gad.225680.113).
-
(2013)
Genes Dev
, vol.27
, pp. 2179-2191
-
-
Jaramillo, M.C.1
Zhang, D.D.2
-
31
-
-
84859445000
-
Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy. Trends Pharmacol
-
Semenza GL. 2012 Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol. Sci. 33, 207–214. (doi:10.1016/j.tips.2012.01.005).
-
(2012)
Sci
, vol.33
, pp. 207-214
-
-
Semenza, G.L.1
-
32
-
-
60549083256
-
Regulation of cancer cell metabolism by hypoxia-inducible factor 1
-
Semenza GL. 2009 Regulation of cancer cell metabolism by hypoxia-inducible factor 1. Semin. Cancer Biol. 19, 12–16. (doi:10.1016/j.semcancer. 2008.11.009).
-
(2009)
Semin. Cancer Biol
, vol.19
, pp. 12-16
-
-
Semenza, G.L.1
-
33
-
-
84904732950
-
Hypoxia, lipids, and cancer: Surviving the harsh tumor microenvironment
-
Ackerman D, Simon MC. 2014 Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment. Trends Cell Biol. 24, 472–478. (doi:10.1016/j.tcb.2014.06.001).
-
(2014)
Trends Cell Biol
, vol.24
, pp. 472-478
-
-
Ackerman, D.1
Simon, M.C.2
-
34
-
-
84899750737
-
Bioenergetic constraints on the evolution of complex life. Cold Spring Harbor Perspect
-
Lane N. 2014 Bioenergetic constraints on the evolution of complex life. Cold Spring Harbor Perspect. Biol. 6, a015982. (doi:10.1101/cshperspect.a015982).
-
(2014)
Biol
, vol.6
-
-
Lane, N.1
-
35
-
-
84988044805
-
The energetics of genome complexity
-
Lane N, Martin W. 2010 The energetics of genome complexity. Nature 467, 929–934. (doi:10.1038/nature09486).
-
(2010)
Nature
, vol.467
, pp. 929-934
-
-
Lane, N.1
Martin, W.2
-
36
-
-
0037364314
-
A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat
-
Eng C, Kiuru M, Fernandez MJ, Aaltonen LA. 2003 A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat. Rev. Cancer 3, 193–202. (doi:10.1038/nrc1013).
-
(2003)
Rev. Cancer
, vol.3
, pp. 193-202
-
-
Eng, C.1
Kiuru, M.2
Fernandez, M.J.3
Aaltonen, L.A.4
-
37
-
-
33746930794
-
Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer
-
King A, Selak MA, Gottlieb E. 2006 Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer. Oncogene 25, 4675–4682. (doi:10.1038/sj.onc.1209594).
-
(2006)
Oncogene
, vol.25
, pp. 4675-4682
-
-
King, A.1
Selak, M.A.2
Gottlieb, E.3
-
38
-
-
84880300456
-
Oncogenic isocitrate dehydrogenase mutations: Mechanisms, models, and clinical opportunities
-
Cairns RA, Mak TW. 2013 Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities. Cancer Discov. 3, 730–741. (doi:10.1158/2159-8290.CD-13-0083).
-
(2013)
Cancer Discov
, vol.3
, pp. 730-741
-
-
Cairns, R.A.1
Mak, T.W.2
-
39
-
-
84886860116
-
TET enzymes, TDG and the dynamics of DNA demethylation
-
Kohli RM, Zhang Y. 2013 TET enzymes, TDG and the dynamics of DNA demethylation. Nature 502, 472–479. (doi:10.1038/nature12750).
-
(2013)
Nature
, vol.502
, pp. 472-479
-
-
Kohli, R.M.1
Zhang, Y.2
-
40
-
-
77957666255
-
Histone methyl transferases and demethylases: Can they link metabolism and transcription?
-
Teperino R, Schoonjans K, Auwerx J. 2010 Histone methyl transferases and demethylases: can they link metabolism and transcription? Cell Metab. 12, 321–327. (doi:10.1016/j.cmet.2010.09.004).
-
(2010)
Cell Metab
, vol.12
, pp. 321-327
-
-
Teperino, R.1
Schoonjans, K.2
Auwerx, J.3
-
41
-
-
84866378702
-
The role of mutations in epigenetic regulators in myeloid malignancies. Nat
-
Shih AH, Abdel-Wahab O, Patel JP, Levine RL. 2012 The role of mutations in epigenetic regulators in myeloid malignancies. Nat. Rev. Cancer 12, 599–612. (doi:10.1038/nrc3343).
-
(2012)
Rev. Cancer
, vol.12
, pp. 599-612
-
-
Shih, A.H.1
Abdel-Wahab, O.2
Patel, J.P.3
Levine, R.L.4
-
42
-
-
84872445265
-
Neutralizing tumor-promoting chronic inflammation: A magic bullet?
-
Coussens LM, Zitvogel L, Palucka AK. 2013 Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science 339, 286–291. (doi:10.1126/science.1232227).
-
(2013)
Science
, vol.339
, pp. 286-291
-
-
Coussens, L.M.1
Zitvogel, L.2
Palucka, A.K.3
-
43
-
-
84908608590
-
The gut microbiota, bacterial metabolites and colorectal cancer. Nat
-
Louis P, Hold GL, Flint HJ. 2014 The gut microbiota, bacterial metabolites and colorectal cancer. Nat. Rev. Microbiol. 12, 661–672. (doi:10.1038/nrmicro3344).
-
(2014)
Rev. Microbiol
, vol.12
, pp. 661-672
-
-
Louis, P.1
Hold, G.L.2
Flint, H.J.3
-
44
-
-
33751214170
-
Marine mammal neoplasia: A review. Vet
-
Newman SJ, Smith SA. 2006 Marine mammal neoplasia: a review. Vet. Pathol. 43, 865–880. (doi:10.1354/vp.43-6-865).
-
(2006)
Pathol
, vol.43
, pp. 865-880
-
-
Newman, S.J.1
Smith, S.A.2
-
45
-
-
0036206864
-
Age distribution of cancer in mice the incidence turnover at old age Toxicol Ind
-
Pompei F, Polkanov M, Wilson R. 2001 Age distribution of cancer in mice: the incidence turnover at old age. Toxicol. Ind. Health 17, 7–16. (doi:10.1191/0748233701th091oa).
-
(2001)
Health
, vol.17
, pp. 7-16
-
-
Pompei, F.1
Polkanov, M.2
Wilson, R.3
-
46
-
-
84957355538
-
Body size and metabolic rate. Physiol
-
Kleiber M. 1947 Body size and metabolic rate. Physiol. Rev. 27, 511–541.
-
(1947)
Rev
, vol.27
, pp. 511-541
-
-
Kleiber, M.1
-
47
-
-
34248364404
-
Scaling of number, size, and metabolic rate of cells with body size in mammals
-
Savage VM, Allen AP, Brown JH, Gillooly JF, Herman AB, Woodruff WH, West GB. 2007 Scaling of number, size, and metabolic rate of cells with body size in mammals. Proc. Natl Acad. Sci. USA 104, 4718–4723. (doi:10.1073/pnas.0611235104).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 4718-4723
-
-
Savage, V.M.1
Allen, A.P.2
Brown, J.H.3
Gillooly, J.F.4
Herman, A.B.5
Woodruff, W.H.6
West, G.B.7
-
48
-
-
0014818006
-
Energy metabolism, body size, and problems of scaling. Fed
-
Schmidt-Nielsen K. 1970 Energy metabolism, body size, and problems of scaling. Fed. Proc. 29, 1524–1532.
-
(1970)
Proc
, vol.29
, pp. 1524-1532
-
-
Schmidt-Nielsen, K.1
-
49
-
-
0037434713
-
Physiology: Why does metabolic rate scale with body size?
-
discussion 4
-
West GB, Savage VM, Gillooly J, Enquist BJ, Woodruff WH, Brown JH. 2003 Physiology: why does metabolic rate scale with body size? Nature 421, 713; discussion 4. (doi:10.1038/421713a).
-
(2003)
Nature
, vol.421
, pp. 713
-
-
West, G.B.1
Savage, V.M.2
Gillooly, J.3
Enquist, B.J.4
Woodruff, W.H.5
Brown, J.H.6
-
50
-
-
0035846161
-
A general model for ontogenetic growth
-
West GB, Brown JH, Enquist BJ. 2001 A general model for ontogenetic growth. Nature 413, 628–631. (doi:10.1038/35098076).
-
(2001)
Nature
, vol.413
, pp. 628-631
-
-
West, G.B.1
Brown, J.H.2
Enquist, B.J.3
-
51
-
-
0033522952
-
The fourth dimension of life: Fractal geometry and allometric scaling of organisms
-
West GB, Brown JH, Enquist BJ. 1999 The fourth dimension of life: fractal geometry and allometric scaling of organisms. Science 284, 1677–1679. (doi:10.1126/science.284.5420.1677).
-
(1999)
Science
, vol.284
, pp. 1677-1679
-
-
West, G.B.1
Brown, J.H.2
Enquist, B.J.3
-
52
-
-
0030932272
-
A general model for the origin of allometric scaling laws in biology
-
West GB, Brown JH, Enquist BJ. 1997 A general model for the origin of allometric scaling laws in biology. Science 276, 122–126. (doi:10.1126/science.276.5309.122).
-
(1997)
Science
, vol.276
, pp. 122-126
-
-
West, G.B.1
Brown, J.H.2
Enquist, B.J.3
-
53
-
-
77950382118
-
Curvature in metabolic scaling
-
Kolokotrones T, Van S, Deeds EJ, Fontana W. 2010 Curvature in metabolic scaling. Nature 464, 753–756. (doi:10.1038/nature08920).
-
(2010)
Nature
, vol.464
, pp. 753-756
-
-
Kolokotrones, T.1
Van, S.2
Deeds, E.J.3
Fontana, W.4
-
54
-
-
84867700214
-
Testing metabolic theories
-
Kearney MR, White CR. 2012 Testing metabolic theories. Am. Nat. 180, 546–565. (doi:10.1086/667860).
-
(2012)
Am. Nat
, vol.180
, pp. 546-565
-
-
Kearney, M.R.1
White, C.R.2
-
55
-
-
78651139476
-
Capillary density in mammals in relation to body size and oxygen consumption
-
Schmidt-Nielsen K, Pennycuik P. 1961 Capillary density in mammals in relation to body size and oxygen consumption. Am. J. Physiol. 200, 746–750.
-
(1961)
Am. J. Physiol
, vol.200
, pp. 746-750
-
-
Schmidt-Nielsen, K.1
Pennycuik, P.2
-
56
-
-
0028504108
-
Capillary blood transit time in muscles in relation to body size and aerobic capacity
-
Kayar SR et al. 1994 Capillary blood transit time in muscles in relation to body size and aerobic capacity. J. Exp. Biol. 194, 69–81.
-
(1994)
J. Exp. Biol
, vol.194
, pp. 69-81
-
-
Kayar, S.R.1
-
57
-
-
45249110411
-
From empirical patterns to theory: A formal metabolic theory of life
-
Sousa T, Domingos T, Kooijman SA. 2008 From empirical patterns to theory: a formal metabolic theory of life. Phil. Trans. R. Soc. B 363, 2453–2464. (doi:10.1098/rstb.2007.2230).
-
(2008)
Phil. Trans. R. Soc. B
, vol.363
, pp. 2453-2464
-
-
Sousa, T.1
Domingos, T.2
Kooijman, S.A.3
-
59
-
-
84890796015
-
Reconciling theories for metabolic scaling
-
Maino JL, Kearney MR, Nisbet RM, Kooijman SA. 2014 Reconciling theories for metabolic scaling. J. Anim. Ecol. 83, 20–29. (doi:10.1111/1365-2656.12085).
-
(2014)
J. Anim. Ecol
, vol.83
, pp. 20-29
-
-
Maino, J.L.1
Kearney, M.R.2
Nisbet, R.M.3
Kooijman, S.A.4
-
60
-
-
33750688150
-
The origin of allometric scaling laws in biology
-
Demetrius L. 2006 The origin of allometric scaling laws in biology. J. Theor. Biol. 243, 455–467. (doi:10.1016/j.jtbi.2006.05.031).
-
(2006)
J. Theor. Biol
, vol.243
, pp. 455-467
-
-
Demetrius, L.1
-
61
-
-
76049129379
-
Quantum metabolism explains the allometric scaling of metabolic rates
-
Demetrius L, Tuszynski JA. 2010 Quantum metabolism explains the allometric scaling of metabolic rates. J. R. Soc. Interface 7, 507–514. (doi:10.1098/rsif.2009.0310).
-
(2010)
J. R. Soc. Interface
, vol.7
, pp. 507-514
-
-
Demetrius, L.1
Tuszynski, J.A.2
-
62
-
-
0028884511
-
Causes of differences in respiration rate of hepatocytes from mammals of different body mass
-
Porter RK, Brand MD. 1995 Causes of differences in respiration rate of hepatocytes from mammals of different body mass. Am. J. Physiol. 269, R1213–R1224.
-
(1995)
Am. J. Physiol
, vol.269
, pp. R1213-R1224
-
-
Porter, R.K.1
Brand, M.D.2
-
63
-
-
84860491005
-
Absence of metabolic rate allometry in an ex vivo model of mammalian skeletal muscle
-
Robb EL, Maddalena LA, Dunlop VA, Foster T, Stuart JA. 2012 Absence of metabolic rate allometry in an ex vivo model of mammalian skeletal muscle. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 162, 157–162. (doi:10.1016/j.cbpa.2012.01.022).
-
(2012)
Comp Biochem Physiol a Mol Integr Physiol
, vol.162
, pp. 157-162
-
-
Robb, E.L.1
Maddalena, L.A.2
Dunlop, V.A.3
Foster, T.4
Stuart, J.A.5
-
64
-
-
34447502416
-
Metabolic rate does not scale with body mass in cultured mammalian cells
-
Brown MF, Gratton TP, Stuart JA. 2007 Metabolic rate does not scale with body mass in cultured mammalian cells. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R2115–R2121. (doi:10.1152/ajpregu.00568.2006).
-
(2007)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.292
, pp. R2115-R2121
-
-
Brown, M.F.1
Gratton, T.P.2
Stuart, J.A.3
-
65
-
-
0019406232
-
Scaling of oxidative and glycolytic enzymes in mammals. Respir
-
Emmett B, Hochachka PW. 1981 Scaling of oxidative and glycolytic enzymes in mammals. Respir. Physiol. 45, 261–272. (doi:10.1016/0034-5687(81)90010-4).
-
(1981)
Physiol
, vol.45
, pp. 261-272
-
-
Emmett, B.1
Hochachka, P.W.2
-
66
-
-
27644580795
-
Clues to the functions of mammalian sleep
-
Siegel JM. 2005 Clues to the functions of mammalian sleep. Nature 437, 1264–1271. (doi:10.1038/nature04285).
-
(2005)
Nature
, vol.437
, pp. 1264-1271
-
-
Siegel, J.M.1
-
67
-
-
0037178643
-
Increases in amino-cupric-silver staining of the supraoptic nucleus after sleep deprivation
-
Eiland MM, Ramanathan L, Gulyani S, Gilliland M, Bergmann BM, Rechtschaffen A, Siegel JM. 2002 Increases in amino-cupric-silver staining of the supraoptic nucleus after sleep deprivation. Brain Res. 945, 1–8. (doi:10.1016/S0006-8993(02)02448-4).
-
(2002)
Brain Res
, vol.945
, pp. 1-8
-
-
Eiland, M.M.1
Ramanathan, L.2
Gulyani, S.3
Gilliland, M.4
Bergmann, B.M.5
Rechtschaffen, A.6
Siegel, J.M.7
-
69
-
-
84885775321
-
Sleep drives metabolite clearance from the adult brain
-
Xie L et al. 2013 Sleep drives metabolite clearance from the adult brain. Science 342, 373–377. (doi:10.1126/science.1241224).
-
(2013)
Science
, vol.342
, pp. 373-377
-
-
Xie, L.1
-
70
-
-
84905994853
-
Effect of 1 night of total sleep deprivation on cerebrospinal fluid beta-amyloid 42 in healthy middle-aged men: A randomized clinical trial
-
Ooms S, Overeem S, Besse K, Rikkert MO, Verbeek M, Claassen JA. 2014 Effect of 1 night of total sleep deprivation on cerebrospinal fluid beta-amyloid 42 in healthy middle-aged men: a randomized clinical trial. JAMA Neurol. 71, 971–977. (doi:10.1001/jamaneurol.2014.1173).
-
(2014)
JAMA Neurol
, vol.71
, pp. 971-977
-
-
Ooms, S.1
Overeem, S.2
Besse, K.3
Rikkert, M.O.4
Verbeek, M.5
Claassen, J.A.6
-
71
-
-
80053310398
-
A quantitative theory of solid tumor growth, metabolic rate and vascularization
-
Herman AB, Savage VM, West GB. 2011 A quantitative theory of solid tumor growth, metabolic rate and vascularization. PLoS ONE 6, e22973. (doi:10.1371/journal.pone.0022973).
-
(2011)
Plos ONE
, vol.6
-
-
Herman, A.B.1
Savage, V.M.2
West, G.B.3
-
72
-
-
84905096743
-
Caloric restriction and cancer: Molecular mechanisms and clinical implications. Trends Mol
-
Meynet O, Ricci JE. 2014 Caloric restriction and cancer: molecular mechanisms and clinical implications. Trends Mol. Med. 20, 419–427. (doi:10.1016/j.molmed.2014.05.001).
-
(2014)
Med
, vol.20
, pp. 419-427
-
-
Meynet, O.1
Ricci, J.E.2
-
73
-
-
74049092809
-
Calories and carcinogenesis: Lessons learned from 30 years of calorie restriction research
-
Hursting SD, Smith SM, Lashinger LM, Harvey AE, Perkins SN. 2010 Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research. Carcinogenesis 31, 83–89. (doi:10.1093/carcin/bgp280).
-
(2010)
Carcinogenesis
, vol.31
, pp. 83-89
-
-
Hursting, S.D.1
Smith, S.M.2
Lashinger, L.M.3
Harvey, A.E.4
Perkins, S.N.5
-
74
-
-
84884150826
-
Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression
-
Wu JJ et al. 2013 Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression. Cell Rep. 4, 913–920. (doi:10.1016/j.celrep.2013.07.030).
-
(2013)
Cell Rep
, vol.4
, pp. 913-920
-
-
Wu, J.J.1
-
75
-
-
84898625747
-
Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin. Cancer Biol
-
Popovich IG, Anisimov VN, Zabezhinski MA, Semenchenko AV, Tyndyk ML, Yurova MN, Blagosklonny MV. 2014 Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin. Cancer Biol. Ther. 15, 586–592. (doi:10.4161/cbt.28164).
-
(2014)
Ther
, vol.15
, pp. 586-592
-
-
Popovich, I.G.1
Anisimov, V.N.2
Zabezhinski, M.A.3
Semenchenko, A.V.4
Tyndyk, M.L.5
Yurova, M.N.6
Blagosklonny, M.V.7
-
76
-
-
83755165458
-
Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
-
Anisimov VN et al. 2011 Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice. Cell Cycle 10, 4230–4236. (doi:10.4161/cc.10.24.18486).
-
(2011)
Cell Cycle
, vol.10
, pp. 4230-4236
-
-
Anisimov, V.N.1
-
77
-
-
84884211823
-
Targeting metabolism for cancer treatment and prevention: Metformin, an old drug with multifaceted effects
-
Pierotti MA, Berrino F, Gariboldi M, Melani C, Mogavero A, Negri T, Pasanisi P, Pilotti S. 2013 Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multifaceted effects. Oncogene 32, 1475–1487. (doi:10.1038/onc.2012.181).
-
(2013)
Oncogene
, vol.32
, pp. 1475-1487
-
-
Pierotti, M.A.1
Berrino, F.2
Gariboldi, M.3
Melani, C.4
Mogavero, A.5
Negri, T.6
Pasanisi, P.7
Pilotti, S.8
-
78
-
-
84883542202
-
Potential applications for biguanides in oncology
-
Pollak M. 2013 Potential applications for biguanides in oncology. J. Clin. Investig. 123, 3693–3700. (doi:10.1172/JCI67232).
-
(2013)
J. Clin. Investig
, vol.123
, pp. 3693-3700
-
-
Pollak, M.1
|