-
1
-
-
0027717002
-
A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11
-
PID: 8294032
-
O′Dowd BF, Heiber M, Chan A, Heng HH, Tsui LC, Kennedy JL, Shi X, Petronis A, George SR, Nguyen T (1993) A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11. Gene 136(1–2):355–360
-
(1993)
Gene
, vol.136
, Issue.1-2
, pp. 355-360
-
-
O′Dowd, B.F.1
Heiber, M.2
Chan, A.3
Heng, H.H.4
Tsui, L.C.5
Kennedy, J.L.6
Shi, X.7
Petronis, A.8
George, S.R.9
Nguyen, T.10
-
2
-
-
0032552988
-
Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor
-
COI: 1:CAS:528:DyaK1cXmvF2msbY%3D, PID: 9792798
-
Tatemoto K, Hosoya M, Habata Y, Fujii R, Kakegawa T, Zou MX, Kawamata Y, Fukusumi S, Hinuma S, Kitada C, Kurokawa T, Onda H, Fujino M (1998) Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun 251(2):471–476. doi:10.1006/bbrc.1998.9489
-
(1998)
Biochem Biophys Res Commun
, vol.251
, Issue.2
, pp. 471-476
-
-
Tatemoto, K.1
Hosoya, M.2
Habata, Y.3
Fujii, R.4
Kakegawa, T.5
Zou, M.X.6
Kawamata, Y.7
Fukusumi, S.8
Hinuma, S.9
Kitada, C.10
Kurokawa, T.11
Onda, H.12
Fujino, M.13
-
3
-
-
0033985447
-
Characterization of apelin, the ligand for the APJ receptor
-
COI: 1:CAS:528:DC%2BD3cXlt1Oi, PID: 10617103
-
Lee DK, Cheng R, Nguyen T, Fan T, Kariyawasam AP, Liu Y, Osmond DH, George SR, O’Dowd BF (2000) Characterization of apelin, the ligand for the APJ receptor. J Neurochem 74(1):34–41
-
(2000)
J Neurochem
, vol.74
, Issue.1
, pp. 34-41
-
-
Lee, D.K.1
Cheng, R.2
Nguyen, T.3
Fan, T.4
Kariyawasam, A.P.5
Liu, Y.6
Osmond, D.H.7
George, S.R.8
O’Dowd, B.F.9
-
4
-
-
35348857484
-
Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemia–reperfusion injury
-
COI: 1:CAS:528:DC%2BD2sXhtlCnsrnK, PID: 17694254
-
Simpkin JC, Yellon DM, Davidson SM, Lim SY, Wynne AM, Smith CC (2007) Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemia–reperfusion injury. Basic Res Cardiol 102(6):518–528. doi:10.1007/s00395-007-0671-2
-
(2007)
Basic Res Cardiol
, vol.102
, Issue.6
, pp. 518-528
-
-
Simpkin, J.C.1
Yellon, D.M.2
Davidson, S.M.3
Lim, S.Y.4
Wynne, A.M.5
Smith, C.C.6
-
5
-
-
0347627799
-
The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity
-
COI: 1:CAS:528:DC%2BD3sXps1Cjsr8%3D, PID: 14675627
-
Zhou N, Zhang X, Fan X, Argyris E, Fang J, Acheampong E, DuBois GC, Pomerantz RJ (2003) The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity. Virology 317(1):84–94
-
(2003)
Virology
, vol.317
, Issue.1
, pp. 84-94
-
-
Zhou, N.1
Zhang, X.2
Fan, X.3
Argyris, E.4
Fang, J.5
Acheampong, E.6
DuBois, G.C.7
Pomerantz, R.J.8
-
6
-
-
84885572090
-
Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma
-
COI: 1:CAS:528:DC%2BC3sXhsV2ntbzN, PID: 23872001
-
Zhen EY, Higgs RE, Gutierrez JA (2013) Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma. Anal Biochem 442(1):1–9. doi:10.1016/j.ab.2013.07.006
-
(2013)
Anal Biochem
, vol.442
, Issue.1
-
-
Zhen, E.Y.1
Higgs, R.E.2
Gutierrez, J.A.3
-
7
-
-
10444230360
-
Apelin signalling: a promising pathway from cloning to pharmacology
-
COI: 1:CAS:528:DC%2BD2cXhtVyqsLnN, PID: 15601620
-
Masri B, Knibiehler B, Audigier Y (2005) Apelin signalling: a promising pathway from cloning to pharmacology. Cell Signal 17(4):415–426. doi:10.1016/j.cellsig.2004.09.018
-
(2005)
Cell Signal
, vol.17
, Issue.4
, pp. 415-426
-
-
Masri, B.1
Knibiehler, B.2
Audigier, Y.3
-
8
-
-
70349245019
-
[Pyr1]apelin-13 identified as the predominant apelin isoform in the human heart: vasoactive mechanisms and inotropic action in disease
-
COI: 1:CAS:528:DC%2BD1MXpsleksL4%3D, PID: 19597036
-
Maguire JJ, Kleinz MJ, Pitkin SL, Davenport AP (2009) [Pyr1]apelin-13 identified as the predominant apelin isoform in the human heart: vasoactive mechanisms and inotropic action in disease. Hypertension 54(3):598–604. doi:10.1161/HYPERTENSIONAHA.109.134619
-
(2009)
Hypertension
, vol.54
, Issue.3
, pp. 598-604
-
-
Maguire, J.J.1
Kleinz, M.J.2
Pitkin, S.L.3
Davenport, A.P.4
-
9
-
-
21444455985
-
Emerging roles of apelin in biology and medicine
-
COI: 1:CAS:528:DC%2BD2MXlvVWgtLk%3D, PID: 15907343
-
Kleinz MJ, Davenport AP (2005) Emerging roles of apelin in biology and medicine. Pharmacol Ther 107(2):198–211. doi:10.1016/j.pharmthera.2005.04.001
-
(2005)
Pharmacol Ther
, vol.107
, Issue.2
, pp. 198-211
-
-
Kleinz, M.J.1
Davenport, A.P.2
-
10
-
-
1542300876
-
Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells
-
COI: 1:CAS:528:DC%2BD2cXhvFajurw%3D, PID: 15003827
-
Kleinz MJ, Davenport AP (2004) Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells. Regul Pept 118(3):119–125. doi:10.1016/j.regpep.2003.11.002
-
(2004)
Regul Pept
, vol.118
, Issue.3
, pp. 119-125
-
-
Kleinz, M.J.1
Davenport, A.P.2
-
11
-
-
75749153648
-
Effects of olmesartan on Apelin/APJ and Akt/endothelial nitric oxide synthase pathway in Dahl rats with end-stage heart failure
-
COI: 1:CAS:528:DC%2BC3cXos1WjsQ%3D%3D, PID: 19904215
-
Fukushima H, Kobayashi N, Takeshima H, Koguchi W, Ishimitsu T (2010) Effects of olmesartan on Apelin/APJ and Akt/endothelial nitric oxide synthase pathway in Dahl rats with end-stage heart failure. J Cardiovasc Pharmacol 55(1):83–88. doi:10.1097/FJC.0b013e3181c87a82
-
(2010)
J Cardiovasc Pharmacol
, vol.55
, Issue.1
, pp. 83-88
-
-
Fukushima, H.1
Kobayashi, N.2
Takeshima, H.3
Koguchi, W.4
Ishimitsu, T.5
-
12
-
-
0042165829
-
Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure
-
COI: 1:CAS:528:DC%2BD3sXmt1Wru7Y%3D, PID: 12914775
-
Foldes G, Horkay F, Szokodi I, Vuolteenaho O, Ilves M, Lindstedt KA, Mayranpaa M, Sarman B, Seres L, Skoumal R, Lako-Futo Z, deChatel R, Ruskoaho H, Toth M (2003) Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure. Biochem Biophys Res Commun 308(3):480–485
-
(2003)
Biochem Biophys Res Commun
, vol.308
, Issue.3
, pp. 480-485
-
-
Foldes, G.1
Horkay, F.2
Szokodi, I.3
Vuolteenaho, O.4
Ilves, M.5
Lindstedt, K.A.6
Mayranpaa, M.7
Sarman, B.8
Seres, L.9
Skoumal, R.10
Lako-Futo, Z.11
deChatel, R.12
Ruskoaho, H.13
Toth, M.14
-
13
-
-
3142746678
-
Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release
-
PID: 15231996
-
De Mota N, Reaux-Le Goazigo A, El Messari S, Chartrel N, Roesch D, Dujardin C, Kordon C, Vaudry H, Moos F, Llorens-Cortes C (2004) Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release. Proc Natl Acad Sci USA 101(28):10464–10469. doi:10.1073/pnas.0403518101
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.28
, pp. 10464-10469
-
-
De Mota, N.1
Reaux-Le Goazigo, A.2
El Messari, S.3
Chartrel, N.4
Roesch, D.5
Dujardin, C.6
Kordon, C.7
Vaudry, H.8
Moos, F.9
Llorens-Cortes, C.10
-
14
-
-
44049090382
-
Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli
-
COI: 1:CAS:528:DC%2BD1cXmtlOgsL4%3D
-
Azizi M, Iturrioz X, Blanchard A, Peyrard S, De Mota N, Chartrel N, Vaudry H, Corvol P, Llorens-Cortes C (2008) Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli. J Am Soc Nephrol JASN 19(5):1015–1024. doi:10.1681/ASN.2007070816
-
(2008)
J Am Soc Nephrol JASN
, vol.19
, Issue.5
, pp. 1015-1024
-
-
Azizi, M.1
Iturrioz, X.2
Blanchard, A.3
Peyrard, S.4
De Mota, N.5
Chartrel, N.6
Vaudry, H.7
Corvol, P.8
Llorens-Cortes, C.9
-
15
-
-
50349086725
-
Vascular effects of apelin in vivo in man
-
COI: 1:CAS:528:DC%2BD1cXhtVyjsbnE, PID: 18772060
-
Japp AG, Cruden NL, Amer DA, Li VK, Goudie EB, Johnston NR, Sharma S, Neilson I, Webb DJ, Megson IL, Flapan AD, Newby DE (2008) Vascular effects of apelin in vivo in man. J Am Coll Cardiol 52(11):908–913. doi:10.1016/j.jacc.2008.06.013
-
(2008)
J Am Coll Cardiol
, vol.52
, Issue.11
, pp. 908-913
-
-
Japp, A.G.1
Cruden, N.L.2
Amer, D.A.3
Li, V.K.4
Goudie, E.B.5
Johnston, N.R.6
Sharma, S.7
Neilson, I.8
Webb, D.J.9
Megson, I.L.10
Flapan, A.D.11
Newby, D.E.12
-
16
-
-
0034647520
-
Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin
-
COI: 1:CAS:528:DC%2BD3cXkvFGjtLs%3D, PID: 10777510
-
Hosoya M, Kawamata Y, Fukusumi S, Fujii R, Habata Y, Hinuma S, Kitada C, Honda S, Kurokawa T, Onda H, Nishimura O, Fujino M (2000) Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin. J Biol Chem 275(28):21061–21067. doi:10.1074/jbc.M908417199
-
(2000)
J Biol Chem
, vol.275
, Issue.28
, pp. 21061-21067
-
-
Hosoya, M.1
Kawamata, Y.2
Fukusumi, S.3
Fujii, R.4
Habata, Y.5
Hinuma, S.6
Kitada, C.7
Honda, S.8
Kurokawa, T.9
Onda, H.10
Nishimura, O.11
Fujino, M.12
-
17
-
-
34248163595
-
Direct effects of apelin on cardiomyocyte contractility and electrophysiology
-
COI: 1:CAS:528:DC%2BD2sXlt1ajs7c%3D, PID: 17466269
-
Farkasfalvi K, Stagg MA, Coppen SR, Siedlecka U, Lee J, Soppa GK, Marczin N, Szokodi I, Yacoub MH, Terracciano CM (2007) Direct effects of apelin on cardiomyocyte contractility and electrophysiology. Biochem Biophys Res Commun 357(4):889–895. doi:10.1016/j.bbrc.2007.04.017
-
(2007)
Biochem Biophys Res Commun
, vol.357
, Issue.4
, pp. 889-895
-
-
Farkasfalvi, K.1
Stagg, M.A.2
Coppen, S.R.3
Siedlecka, U.4
Lee, J.5
Soppa, G.K.6
Marczin, N.7
Szokodi, I.8
Yacoub, M.H.9
Terracciano, C.M.10
-
18
-
-
70350462121
-
Endogenous regulation of cardiovascular function by apelin-APJ
-
COI: 1:CAS:528:DC%2BD1MXhsValsbnO, PID: 19767528
-
Charo DN, Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T (2009) Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol 297(5):H1904–H1913. doi:10.1152/ajpheart.00686.2009
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.5
, pp. 1904-1913
-
-
Charo, D.N.1
Ho, M.2
Fajardo, G.3
Kawana, M.4
Kundu, R.K.5
Sheikh, A.Y.6
Finsterbach, T.P.7
Leeper, N.J.8
Ernst, K.V.9
Chen, M.M.10
Ho, Y.D.11
Chun, H.J.12
Bernstein, D.13
Ashley, E.A.14
Quertermous, T.15
-
19
-
-
84890856728
-
ELABELA: a hormone essential for heart development signals via the apelin receptor
-
COI: 1:CAS:528:DC%2BC3sXhvFGitbnN, PID: 24316148
-
Chng SC, Ho L, Tian J, Reversade B (2013) ELABELA: a hormone essential for heart development signals via the apelin receptor. Dev Cell 27(6):672–680. doi:10.1016/j.devcel.2013.11.002
-
(2013)
Dev Cell
, vol.27
, Issue.6
, pp. 672-680
-
-
Chng, S.C.1
Ho, L.2
Tian, J.3
Reversade, B.4
-
20
-
-
84903712144
-
ELABELA: a novel hormone in cardiac development acting as a new endogenous ligand for the APJ receptor
-
PID: 24829400
-
Xie F, Lv D, Chen L (2014) ELABELA: a novel hormone in cardiac development acting as a new endogenous ligand for the APJ receptor. Acta Biochim Biophys Sin 46(7):620–622. doi:10.1093/abbs/gmu032
-
(2014)
Acta Biochim Biophys Sin
, vol.46
, Issue.7
, pp. 620-622
-
-
Xie, F.1
Lv, D.2
Chen, L.3
-
21
-
-
84865146998
-
APJ acts as a dual receptor in cardiac hypertrophy
-
COI: 1:CAS:528:DC%2BC38XhtFWjtbjF, PID: 22810587
-
Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, Ashley E, Mercola M, Brown JH, Ruiz-Lozano P (2012) APJ acts as a dual receptor in cardiac hypertrophy. Nature 488(7411):394–398. doi:10.1038/nature11263
-
(2012)
Nature
, vol.488
, Issue.7411
, pp. 394-398
-
-
Scimia, M.C.1
Hurtado, C.2
Ray, S.3
Metzler, S.4
Wei, K.5
Wang, J.6
Woods, C.E.7
Purcell, N.H.8
Catalucci, D.9
Akasaka, T.10
Bueno, O.F.11
Vlasuk, G.P.12
Kaliman, P.13
Bodmer, R.14
Smith, L.H.15
Ashley, E.16
Mercola, M.17
Brown, J.H.18
Ruiz-Lozano, P.19
-
22
-
-
0035876612
-
The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism
-
COI: 1:CAS:528:DC%2BD3MXjvV2rtrY%3D, PID: 11384769
-
Tatemoto K, Takayama K, Zou MX, Kumaki I, Zhang W, Kumano K, Fujimiya M (2001) The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 99(2–3):87–92
-
(2001)
Regul Pept
, vol.99
, Issue.2-3
, pp. 87-92
-
-
Tatemoto, K.1
Takayama, K.2
Zou, M.X.3
Kumaki, I.4
Zhang, W.5
Kumano, K.6
Fujimiya, M.7
-
23
-
-
0037868944
-
Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats
-
COI: 1:CAS:528:DC%2BD3sXksVegsbc%3D, PID: 12798955
-
Cheng X, Cheng XS, Pang CC (2003) Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats. Eur J Pharmacol 470(3):171–175
-
(2003)
Eur J Pharmacol
, vol.470
, Issue.3
, pp. 171-175
-
-
Cheng, X.1
Cheng, X.S.2
Pang, C.C.3
-
24
-
-
19944373052
-
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo
-
COI: 1:CAS:528:DC%2BD2cXhtFCqt7vM, PID: 15621035
-
Ashley EA, Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A, Deng A, Eichhorn J, Mahajan R, Agrawal R, Greve J, Robbins R, Patterson AJ, Bernstein D, Quertermous T (2005) The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Cardiovasc Res 65(1):73–82. doi:10.1016/j.cardiores.2004.08.018
-
(2005)
Cardiovasc Res
, vol.65
, Issue.1
, pp. 73-82
-
-
Ashley, E.A.1
Powers, J.2
Chen, M.3
Kundu, R.4
Finsterbach, T.5
Caffarelli, A.6
Deng, A.7
Eichhorn, J.8
Mahajan, R.9
Agrawal, R.10
Greve, J.11
Robbins, R.12
Patterson, A.J.13
Bernstein, D.14
Quertermous, T.15
-
25
-
-
4644320632
-
Apelin has in vivo inotropic effects on normal and failing hearts
-
PID: 15364861
-
Berry MF, Pirolli TJ, Jayasankar V, Burdick J, Morine KJ, Gardner TJ, Woo YJ (2004) Apelin has in vivo inotropic effects on normal and failing hearts. Circulation 110(11 Suppl 1):II187–II193. doi:10.1161/01.CIR.0000138382.57325.5c
-
(2004)
Circulation
, vol.110
, pp. 187-193
-
-
Berry, M.F.1
Pirolli, T.J.2
Jayasankar, V.3
Burdick, J.4
Morine, K.J.5
Gardner, T.J.6
Woo, Y.J.7
-
26
-
-
33745150754
-
Role of angiotensin II in cardiovascular disease therapeutic implications of more than a century of research
-
COI: 1:CAS:528:DC%2BD28XmtlKgtLk%3D
-
Ferrario CM (2006) Role of angiotensin II in cardiovascular disease therapeutic implications of more than a century of research. J Renin Angiotensin Aldosterone Syst JRAAS 7(1):3–14. doi:10.3317/jraas.2006.003
-
(2006)
J Renin Angiotensin Aldosterone Syst JRAAS
, vol.7
, Issue.1
, pp. 3-14
-
-
Ferrario, C.M.1
-
27
-
-
34247113814
-
Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology
-
COI: 1:CAS:528:DC%2BD2sXislehtr4%3D, PID: 17346243
-
Higuchi S, Ohtsu H, Suzuki H, Shirai H, Frank GD, Eguchi S (2007) Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology. Clin Sci 112(8):417–428. doi:10.1042/CS20060342
-
(2007)
Clin Sci
, vol.112
, Issue.8
, pp. 417-428
-
-
Higuchi, S.1
Ohtsu, H.2
Suzuki, H.3
Shirai, H.4
Frank, G.D.5
Eguchi, S.6
-
28
-
-
84874232168
-
The apelin receptor inhibits the angiotensin II type 1 receptor via allosteric trans-inhibition
-
COI: 1:CAS:528:DC%2BC3sXjvVWqtLk%3D, PID: 22935142
-
Siddiquee K, Hampton J, McAnally D, May L, Smith L (2013) The apelin receptor inhibits the angiotensin II type 1 receptor via allosteric trans-inhibition. Br J Pharmacol 168(5):1104–1117. doi:10.1111/j.1476-5381.2012.02192.x
-
(2013)
Br J Pharmacol
, vol.168
, Issue.5
, pp. 1104-1117
-
-
Siddiquee, K.1
Hampton, J.2
McAnally, D.3
May, L.4
Smith, L.5
-
29
-
-
84862284803
-
Targeting the ACE2 and apelin pathways are novel therapies for heart failure: opportunities and challenges
-
PID: 22655211
-
Kazemi-Bajestani SM, Patel VB, Wang W, Oudit GY (2012) Targeting the ACE2 and apelin pathways are novel therapies for heart failure: opportunities and challenges. Cardiol Res Pract 2012:823193. doi:10.1155/2012/823193
-
(2012)
Cardiol Res Pract
, vol.2012
, pp. 823193
-
-
Kazemi-Bajestani, S.M.1
Patel, V.B.2
Wang, W.3
Oudit, G.Y.4
-
30
-
-
84890090677
-
Apelin is a positive regulator of ACE2 in failing hearts
-
COI: 1:CAS:528:DC%2BC3sXhvFSqurzI, PID: 24177423
-
Sato T, Suzuki T, Watanabe H, Kadowaki A, Fukamizu A, Liu PP, Kimura A, Ito H, Penninger JM, Imai Y, Kuba K (2013) Apelin is a positive regulator of ACE2 in failing hearts. J Clin Invest 123(12):5203–5211. doi:10.1172/JCI69608
-
(2013)
J Clin Invest
, vol.123
, Issue.12
, pp. 5203-5211
-
-
Sato, T.1
Suzuki, T.2
Watanabe, H.3
Kadowaki, A.4
Fukamizu, A.5
Liu, P.P.6
Kimura, A.7
Ito, H.8
Penninger, J.M.9
Imai, Y.10
Kuba, K.11
-
32
-
-
55849094397
-
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
-
COI: 1:CAS:528:DC%2BD1cXht1ChsrrI, PID: 18769630
-
Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T (2008) Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest 118(10):3343–3354. doi:10.1172/JCI34871
-
(2008)
J Clin Invest
, vol.118
, Issue.10
, pp. 3343-3354
-
-
Chun, H.J.1
Ali, Z.A.2
Kojima, Y.3
Kundu, R.K.4
Sheikh, A.Y.5
Agrawal, R.6
Zheng, L.7
Leeper, N.J.8
Pearl, N.E.9
Patterson, A.J.10
Anderson, J.P.11
Tsao, P.S.12
Lenardo, M.J.13
Ashley, E.A.14
Quertermous, T.15
-
33
-
-
79958129079
-
Non-activated APJ suppresses the angiotensin II type 1 receptor, whereas apelin-activated APJ acts conversely
-
COI: 1:CAS:528:DC%2BC3MXntVyjt7k%3D, PID: 21412239
-
Sun X, Iida S, Yoshikawa A, Senbonmatsu R, Imanaka K, Maruyama K, Nishimura S, Inagami T, Senbonmatsu T (2011) Non-activated APJ suppresses the angiotensin II type 1 receptor, whereas apelin-activated APJ acts conversely. Hypertens Res 34(6):701–706. doi:10.1038/hr.2011.19
-
(2011)
Hypertens Res
, vol.34
, Issue.6
, pp. 701-706
-
-
Sun, X.1
Iida, S.2
Yoshikawa, A.3
Senbonmatsu, R.4
Imanaka, K.5
Maruyama, K.6
Nishimura, S.7
Inagami, T.8
Senbonmatsu, T.9
-
34
-
-
77955981900
-
Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction
-
COI: 1:CAS:528:DC%2BC3cXhtVeksbrJ, PID: 20679547, 718 p following 728
-
Zhong J, Basu R, Guo D, Chow FL, Byrns S, Schuster M, Loibner H, Wang XH, Penninger JM, Kassiri Z, Oudit GY (2010) Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction. Circulation 122(7):717–728. doi:10.1161/CIRCULATIONAHA.110.955369 718 p following 728
-
(2010)
Circulation
, vol.122
, Issue.7
, pp. 717-728
-
-
Zhong, J.1
Basu, R.2
Guo, D.3
Chow, F.L.4
Byrns, S.5
Schuster, M.6
Loibner, H.7
Wang, X.H.8
Penninger, J.M.9
Kassiri, Z.10
Oudit, G.Y.11
-
35
-
-
84875214685
-
Prolonged treatment with angiotensin 1–7 improves endothelial function in diet-induced obesity
-
COI: 1:CAS:528:DC%2BC3sXjsVKgurw%3D, PID: 23425706
-
Beyer AM, Guo DF, Rahmouni K (2013) Prolonged treatment with angiotensin 1–7 improves endothelial function in diet-induced obesity. J Hypertens 31(4):730–738. doi:10.1097/HJH.0b013e32835ecbe5
-
(2013)
J Hypertens
, vol.31
, Issue.4
, pp. 730-738
-
-
Beyer, A.M.1
Guo, D.F.2
Rahmouni, K.3
-
36
-
-
0038053724
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1–9
-
COI: 1:CAS:528:DC%2BD3MXhslOisr8%3D, PID: 10969042
-
Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robison K, Jeyaseelan R, Breitbart RE, Acton S (2000) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1–9. Circ Res 87(5):E1–E9
-
(2000)
Circ Res
, vol.87
, Issue.5
, pp. 1-9
-
-
Donoghue, M.1
Hsieh, F.2
Baronas, E.3
Godbout, K.4
Gosselin, M.5
Stagliano, N.6
Donovan, M.7
Woolf, B.8
Robison, K.9
Jeyaseelan, R.10
Breitbart, R.E.11
Acton, S.12
-
37
-
-
84895138619
-
Angiotensin-(1–7) and angiotensin-(1–9): function in cardiac and vascular remodelling
-
COI: 1:CAS:528:DC%2BC2cXktVSgsbw%3D, PID: 24593683
-
McKinney CA, Fattah C, Loughrey CM, Milligan G, Nicklin SA (2014) Angiotensin-(1–7) and angiotensin-(1–9): function in cardiac and vascular remodelling. Clin Sci 126(12):815–827. doi:10.1042/CS20130436
-
(2014)
Clin Sci
, vol.126
, Issue.12
, pp. 815-827
-
-
McKinney, C.A.1
Fattah, C.2
Loughrey, C.M.3
Milligan, G.4
Nicklin, S.A.5
-
38
-
-
84896315328
-
Angiotensin-(1–9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis
-
COI: 1:CAS:528:DC%2BC2cXjs1Gqsb8%3D, PID: 24463937
-
Ocaranza MP, Moya J, Barrientos V, Alzamora R, Hevia D, Morales C, Pinto M, Escudero N, Garcia L, Novoa U, Ayala P, Diaz-Araya G, Godoy I, Chiong M, Lavandero S, Jalil JE, Michea L (2014) Angiotensin-(1–9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis. J Hypertens 32(4):771–783. doi:10.1097/HJH.0000000000000094
-
(2014)
J Hypertens
, vol.32
, Issue.4
, pp. 771-783
-
-
Ocaranza, M.P.1
Moya, J.2
Barrientos, V.3
Alzamora, R.4
Hevia, D.5
Morales, C.6
Pinto, M.7
Escudero, N.8
Garcia, L.9
Novoa, U.10
Ayala, P.11
Diaz-Araya, G.12
Godoy, I.13
Chiong, M.14
Lavandero, S.15
Jalil, J.E.16
Michea, L.17
-
39
-
-
84856257062
-
Angiotensin-(1–9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor
-
COI: 1:CAS:528:DC%2BC38XotVeksg%3D%3D, PID: 22184331
-
Flores-Munoz M, Work LM, Douglas K, Denby L, Dominiczak AF, Graham D, Nicklin SA (2012) Angiotensin-(1–9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension 59(2):300–307. doi:10.1161/HYPERTENSIONAHA.111.177485
-
(2012)
Hypertension
, vol.59
, Issue.2
, pp. 300-307
-
-
Flores-Munoz, M.1
Work, L.M.2
Douglas, K.3
Denby, L.4
Dominiczak, A.F.5
Graham, D.6
Nicklin, S.A.7
-
40
-
-
18544378161
-
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
-
COI: 1:CAS:528:DC%2BD38XjslSgsbo%3D, PID: 11815627
-
Vickers C, Hales P, Kaushik V, Dick L, Gavin J, Tang J, Godbout K, Parsons T, Baronas E, Hsieh F, Acton S, Patane M, Nichols A, Tummino P (2002) Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 277(17):14838–14843. doi:10.1074/jbc.M200581200
-
(2002)
J Biol Chem
, vol.277
, Issue.17
, pp. 14838-14843
-
-
Vickers, C.1
Hales, P.2
Kaushik, V.3
Dick, L.4
Gavin, J.5
Tang, J.6
Godbout, K.7
Parsons, T.8
Baronas, E.9
Hsieh, F.10
Acton, S.11
Patane, M.12
Nichols, A.13
Tummino, P.14
-
41
-
-
79958049167
-
Apelin-13 limits infarct size and improves cardiac postischemic mechanical recovery only if given after ischemia
-
COI: 1:CAS:528:DC%2BC3MXot1Grsrc%3D, PID: 21378145
-
Rastaldo R, Cappello S, Folino A, Berta GN, Sprio AE, Losano G, Samaja M, Pagliaro P (2011) Apelin-13 limits infarct size and improves cardiac postischemic mechanical recovery only if given after ischemia. Am J Physiol Heart Circ Physiol 300(6):H2308–H2315. doi:10.1152/ajpheart.01177.2010
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, Issue.6
, pp. 2308-2315
-
-
Rastaldo, R.1
Cappello, S.2
Folino, A.3
Berta, G.N.4
Sprio, A.E.5
Losano, G.6
Samaja, M.7
Pagliaro, P.8
-
42
-
-
33748800495
-
Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis
-
COI: 1:CAS:528:DC%2BD28XpvFeksLs%3D, PID: 16876154
-
Inui M, Fukui A, Ito Y, Asashima M (2006) Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis. Dev Biol 298(1):188–200. doi:10.1016/j.ydbio.2006.06.028
-
(2006)
Dev Biol
, vol.298
, Issue.1
, pp. 188-200
-
-
Inui, M.1
Fukui, A.2
Ito, Y.3
Asashima, M.4
-
43
-
-
84861726051
-
Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells
-
COI: 1:CAS:528:DC%2BC38XosVektr0%3D, PID: 22675543
-
Wang IN, Wang X, Ge X, Anderson J, Ho M, Ashley E, Liu J, Butte MJ, Yazawa M, Dolmetsch RE, Quertermous T, Yang PC (2012) Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells. PLoS One 7(6):e38328. doi:10.1371/journal.pone.0038328
-
(2012)
PLoS One
, vol.7
, Issue.6
, pp. 38328
-
-
Wang, I.N.1
Wang, X.2
Ge, X.3
Anderson, J.4
Ho, M.5
Ashley, E.6
Liu, J.7
Butte, M.J.8
Yazawa, M.9
Dolmetsch, R.E.10
Quertermous, T.11
Yang, P.C.12
-
44
-
-
84880299608
-
Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development
-
COI: 1:CAS:528:DC%2BC3sXpvVyiurs%3D, PID: 23603510
-
Kang Y, Kim J, Anderson JP, Wu J, Gleim SR, Kundu RK, McLean DL, Kim JD, Park H, Jin SW, Hwa J, Quertermous T, Chun HJ (2013) Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development. Circ Res 113(1):22–31. doi:10.1161/CIRCRESAHA.113.301324
-
(2013)
Circ Res
, vol.113
, Issue.1
, pp. 22-31
-
-
Kang, Y.1
Kim, J.2
Anderson, J.P.3
Wu, J.4
Gleim, S.R.5
Kundu, R.K.6
McLean, D.L.7
Kim, J.D.8
Park, H.9
Jin, S.W.10
Hwa, J.11
Quertermous, T.12
Chun, H.J.13
-
45
-
-
0035668442
-
Expression of the murine msr/apj receptor and its ligand apelin is upregulated during formation of the retinal vessels
-
COI: 1:CAS:528:DC%2BD3MXovF2ht74%3D, PID: 11744380
-
Saint-Geniez M, Masri B, Malecaze F, Knibiehler B, Audigier Y (2002) Expression of the murine msr/apj receptor and its ligand apelin is upregulated during formation of the retinal vessels. Mech Dev 110(1–2):183–186
-
(2002)
Mech Dev
, vol.110
, Issue.1-2
, pp. 183-186
-
-
Saint-Geniez, M.1
Masri, B.2
Malecaze, F.3
Knibiehler, B.4
Audigier, Y.5
-
46
-
-
0032811273
-
Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ
-
COI: 1:CAS:528:DyaK1MXjs1Shurs%3D, PID: 10473142
-
Devic E, Rizzoti K, Bodin S, Knibiehler B, Audigier Y (1999) Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ. Mech Dev 84(1–2):199–203
-
(1999)
Mech Dev
, vol.84
, Issue.1-2
, pp. 199-203
-
-
Devic, E.1
Rizzoti, K.2
Bodin, S.3
Knibiehler, B.4
Audigier, Y.5
-
47
-
-
0030273124
-
Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis
-
COI: 1:CAS:528:DyaK28XmsVymtbs%3D, PID: 8951791
-
Devic E, Paquereau L, Vernier P, Knibiehler B, Audigier Y (1996) Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis. Mech Dev 59(2):129–140
-
(1996)
Mech Dev
, vol.59
, Issue.2
, pp. 129-140
-
-
Devic, E.1
Paquereau, L.2
Vernier, P.3
Knibiehler, B.4
Audigier, Y.5
-
48
-
-
33745947584
-
Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo
-
COI: 1:CAS:528:DC%2BD28XntV2mu7s%3D, PID: 16750822
-
Cox CM, D’Agostino SL, Miller MK, Heimark RL, Krieg PA (2006) Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo. Dev Biol 296(1):177–189. doi:10.1016/j.ydbio.2006.04.452
-
(2006)
Dev Biol
, vol.296
, Issue.1
, pp. 177-189
-
-
Cox, C.M.1
D’Agostino, S.L.2
Miller, M.K.3
Heimark, R.L.4
Krieg, P.A.5
-
49
-
-
0041696762
-
The msr/apj gene encoding the apelin receptor is an early and specific marker of the venous phenotype in the retinal vasculature
-
COI: 1:CAS:528:DC%2BD3sXmt1WktrY%3D
-
Saint-Geniez M, Argence CB, Knibiehler B, Audigier Y (2003) The msr/apj gene encoding the apelin receptor is an early and specific marker of the venous phenotype in the retinal vasculature. Gene Expr Patterns GEP 3(4):467–472
-
(2003)
Gene Expr Patterns GEP
, vol.3
, Issue.4
, pp. 467-472
-
-
Saint-Geniez, M.1
Argence, C.B.2
Knibiehler, B.3
Audigier, Y.4
-
50
-
-
53449098424
-
Apelin-APJ signaling in retinal angiogenesis
-
COI: 1:CAS:528:DC%2BD1cXht1WrsrvE, PID: 18799795
-
Kojima Y, Quertermous T (2008) Apelin-APJ signaling in retinal angiogenesis. Arterioscler Thromb Vasc Biol 28(10):1687–1688. doi:10.1161/ATVBAHA.108.174847
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, Issue.10
, pp. 1687-1688
-
-
Kojima, Y.1
Quertermous, T.2
-
51
-
-
7644230704
-
Apelin is a novel angiogenic factor in retinal endothelial cells
-
COI: 1:CAS:528:DC%2BD2cXpsVOlsr0%3D, PID: 15530405
-
Kasai A, Shintani N, Oda M, Kakuda M, Hashimoto H, Matsuda T, Hinuma S, Baba A (2004) Apelin is a novel angiogenic factor in retinal endothelial cells. Biochem Biophys Res Commun 325(2):395–400. doi:10.1016/j.bbrc.2004.10.042
-
(2004)
Biochem Biophys Res Commun
, vol.325
, Issue.2
, pp. 395-400
-
-
Kasai, A.1
Shintani, N.2
Oda, M.3
Kakuda, M.4
Hashimoto, H.5
Matsuda, T.6
Hinuma, S.7
Baba, A.8
-
52
-
-
84899544045
-
Apelin-13 stimulates angiogenesis by promoting crosstalk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells
-
COI: 1:CAS:528:DC%2BC2cXhtVeltLvN
-
Yang X, Zhu W, Zhang P, Chen K, Zhao L, Li J, Wei M, Liu M (2014) Apelin-13 stimulates angiogenesis by promoting crosstalk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells. Molecular Med Rep 9(5):1590–1596. doi:10.3892/mmr.2014.1984
-
(2014)
Molecular Med Rep
, vol.9
, Issue.5
, pp. 1590-1596
-
-
Yang, X.1
Zhu, W.2
Zhang, P.3
Chen, K.4
Zhao, L.5
Li, J.6
Wei, M.7
Liu, M.8
-
53
-
-
77951078472
-
Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia
-
COI: 1:CAS:528:DC%2BC3cXltlWqsrY%3D, PID: 20185589
-
Kidoya H, Naito H, Takakura N (2010) Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia. Blood 115(15):3166–3174. doi:10.1182/blood-2009-07-232306
-
(2010)
Blood
, vol.115
, Issue.15
, pp. 3166-3174
-
-
Kidoya, H.1
Naito, H.2
Takakura, N.3
-
54
-
-
84887527968
-
Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia–reperfusion injury: therapeutic potential of synthetic Apelin analogues
-
PID: 23817469
-
Wang W, McKinnie SM, Patel VB, Haddad G, Wang Z, Zhabyeyev P, Das SK, Basu R, McLean B, Kandalam V, Penninger JM, Kassiri Z, Vederas JC, Murray AG, Oudit GY (2013) Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia–reperfusion injury: therapeutic potential of synthetic Apelin analogues. J Am Heart Assoc 2(4):e000249. doi:10.1161/JAHA.113.000249
-
(2013)
J Am Heart Assoc
, vol.2
, Issue.4
, pp. 000249
-
-
Wang, W.1
McKinnie, S.M.2
Patel, V.B.3
Haddad, G.4
Wang, Z.5
Zhabyeyev, P.6
Das, S.K.7
Basu, R.8
McLean, B.9
Kandalam, V.10
Penninger, J.M.11
Kassiri, Z.12
Vederas, J.C.13
Murray, A.G.14
Oudit, G.Y.15
-
55
-
-
0030911475
-
Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C
-
COI: 1:CAS:528:DyaK2sXjsFKqtb4%3D, PID: 9162005
-
Lin Q, Schwarz J, Bucana C, Olson EN (1997) Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 276(5317):1404–1407
-
(1997)
Science
, vol.276
, Issue.5317
, pp. 1404-1407
-
-
Lin, Q.1
Schwarz, J.2
Bucana, C.3
Olson, E.N.4
-
56
-
-
0036851837
-
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor
-
COI: 1:CAS:528:DC%2BD38XotlWlsrk%3D, PID: 12379849
-
Naya FJ, Black BL, Wu H, Bassel-Duby R, Richardson JA, Hill JA, Olson EN (2002) Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat Med 8(11):1303–1309. doi:10.1038/nm789
-
(2002)
Nat Med
, vol.8
, Issue.11
, pp. 1303-1309
-
-
Naya, F.J.1
Black, B.L.2
Wu, H.3
Bassel-Duby, R.4
Richardson, J.A.5
Hill, J.A.6
Olson, E.N.7
-
57
-
-
0037035480
-
Angiostatin inhibits coronary angiogenesis during impaired production of nitric oxide
-
COI: 1:CAS:528:DC%2BD38XktlOku7o%3D, PID: 11994253
-
Matsunaga T, Weihrauch DW, Moniz MC, Tessmer J, Warltier DC, Chilian WM (2002) Angiostatin inhibits coronary angiogenesis during impaired production of nitric oxide. Circulation 105(18):2185–2191
-
(2002)
Circulation
, vol.105
, Issue.18
, pp. 2185-2191
-
-
Matsunaga, T.1
Weihrauch, D.W.2
Moniz, M.C.3
Tessmer, J.4
Warltier, D.C.5
Chilian, W.M.6
-
58
-
-
0037035443
-
Nitric oxide and angiogenesis
-
PID: 11994243
-
Cooke JP, Losordo DW (2002) Nitric oxide and angiogenesis. Circulation 105(18):2133–2135
-
(2002)
Circulation
, vol.105
, Issue.18
, pp. 2133-2135
-
-
Cooke, J.P.1
Losordo, D.W.2
-
59
-
-
38949194007
-
Spatial and temporal role of the apelin/APJ system in the caliber size regulation of blood vessels during angiogenesis
-
COI: 1:CAS:528:DC%2BD1cXhs1KgtL0%3D, PID: 18200044
-
Kidoya H, Ueno M, Yamada Y, Mochizuki N, Nakata M, Yano T, Fujii R, Takakura N (2008) Spatial and temporal role of the apelin/APJ system in the caliber size regulation of blood vessels during angiogenesis. EMBO J 27(3):522–534. doi:10.1038/sj.emboj.7601982
-
(2008)
EMBO J
, vol.27
, Issue.3
, pp. 522-534
-
-
Kidoya, H.1
Ueno, M.2
Yamada, Y.3
Mochizuki, N.4
Nakata, M.5
Yano, T.6
Fujii, R.7
Takakura, N.8
-
60
-
-
2942711581
-
Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo
-
COI: 1:CAS:528:DC%2BD2cXkvVWgs7s%3D, PID: 15087458
-
Ishida J, Hashimoto T, Hashimoto Y, Nishiwaki S, Iguchi T, Harada S, Sugaya T, Matsuzaki H, Yamamoto R, Shiota N, Okunishi H, Kihara M, Umemura S, Sugiyama F, Yagami K, Kasuya Y, Mochizuki N, Fukamizu A (2004) Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo. J Biol Chem 279(25):26274–26279. doi:10.1074/jbc.M404149200
-
(2004)
J Biol Chem
, vol.279
, Issue.25
, pp. 26274-26279
-
-
Ishida, J.1
Hashimoto, T.2
Hashimoto, Y.3
Nishiwaki, S.4
Iguchi, T.5
Harada, S.6
Sugaya, T.7
Matsuzaki, H.8
Yamamoto, R.9
Shiota, N.10
Okunishi, H.11
Kihara, M.12
Umemura, S.13
Sugiyama, F.14
Yagami, K.15
Kasuya, Y.16
Mochizuki, N.17
Fukamizu, A.18
-
61
-
-
77955655868
-
Hemodynamic effect of apelin in a canine model of acute pulmonary thromboembolism
-
COI: 1:CAS:528:DC%2BC3cXhtVaqurvO, PID: 20561551
-
Feng JH, Li WM, Wu XP, Tan XY, Gao YH, Han CL, Li SQ, Xie HN (2010) Hemodynamic effect of apelin in a canine model of acute pulmonary thromboembolism. Peptides 31(9):1772–1778. doi:10.1016/j.peptides.2010.06.004
-
(2010)
Peptides
, vol.31
, Issue.9
, pp. 1772-1778
-
-
Feng, J.H.1
Li, W.M.2
Wu, X.P.3
Tan, X.Y.4
Gao, Y.H.5
Han, C.L.6
Li, S.Q.7
Xie, H.N.8
-
62
-
-
9944257926
-
Central and peripheral cardiovascular actions of apelin in conscious rats
-
COI: 1:CAS:528:DC%2BD2cXhtVCltrfJ, PID: 15582714
-
Kagiyama S, Fukuhara M, Matsumura K, Lin Y, Fujii K, Iida M (2005) Central and peripheral cardiovascular actions of apelin in conscious rats. Regul Pept 125(1–3):55–59. doi:10.1016/j.regpep.2004.07.033
-
(2005)
Regul Pept
, vol.125
, Issue.1-3
, pp. 55-59
-
-
Kagiyama, S.1
Fukuhara, M.2
Matsumura, K.3
Lin, Y.4
Fujii, K.5
Iida, M.6
-
63
-
-
0035084443
-
[(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man
-
COI: 1:CAS:528:DC%2BD3MXisFWit7s%3D, PID: 11250876
-
Katugampola SD, Maguire JJ, Matthewson SR, Davenport AP (2001) [(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man. Br J Pharmacol 132(6):1255–1260. doi:10.1038/sj.bjp.0703939
-
(2001)
Br J Pharmacol
, vol.132
, Issue.6
, pp. 1255-1260
-
-
Katugampola, S.D.1
Maguire, J.J.2
Matthewson, S.R.3
Davenport, A.P.4
-
64
-
-
84875984219
-
Apelin elevates blood pressure in ICR mice with LNAME induced endothelial dysfunction
-
COI: 1:CAS:528:DC%2BC3sXntFWkurk%3D, PID: 23525196
-
Nagano K, Ishida J, Unno M, Matsukura T, Fukamizu A (2013) Apelin elevates blood pressure in ICR mice with LNAME induced endothelial dysfunction. Mol Med Rep 7(5):1371–1375. doi:10.3892/mmr.2013.1378
-
(2013)
Mol Med Rep
, vol.7
, Issue.5
, pp. 1371-1375
-
-
Nagano, K.1
Ishida, J.2
Unno, M.3
Matsukura, T.4
Fukamizu, A.5
-
65
-
-
84883297234
-
Apelin-13 deteriorates hypertension in rats after damage of the vascular endothelium by ADMA
-
COI: 1:CAS:528:DC%2BC3sXht12it7jM, PID: 23984675
-
Han X, Zhang DL, Yin DX, Zhang QD, Liu WH (2013) Apelin-13 deteriorates hypertension in rats after damage of the vascular endothelium by ADMA. Can J Physiol Pharmacol 91(9):708–714. doi:10.1139/cjpp-2013-0046
-
(2013)
Can J Physiol Pharmacol
, vol.91
, Issue.9
, pp. 708-714
-
-
Han, X.1
Zhang, D.L.2
Yin, D.X.3
Zhang, Q.D.4
Liu, W.H.5
-
66
-
-
33847752255
-
Interactions between apelin and angiotensin II on rat portal vein
-
COI: 1:CAS:528:DC%2BD2sXjs1WltL8%3D
-
Gurzu B, Petrescu BC, Costuleanu M, Petrescu G (2006) Interactions between apelin and angiotensin II on rat portal vein. J Renin Angiotensin Aldosterone Syst JRAAS 7(4):212–216. doi:10.3317/jraas.2006.040
-
(2006)
J Renin Angiotensin Aldosterone Syst JRAAS
, vol.7
, Issue.4
, pp. 212-216
-
-
Gurzu, B.1
Petrescu, B.C.2
Costuleanu, M.3
Petrescu, G.4
-
67
-
-
77954336925
-
Modulation of the apelin/APJ system in heart failure and atherosclerosis in man
-
COI: 1:CAS:528:DC%2BC3cXhtlSju7rF, PID: 20649580
-
Pitkin SL, Maguire JJ, Kuc RE, Davenport AP (2010) Modulation of the apelin/APJ system in heart failure and atherosclerosis in man. Br J Pharmacol 160(7):1785–1795. doi:10.1111/j.1476-5381.2010.00821.x
-
(2010)
Br J Pharmacol
, vol.160
, Issue.7
, pp. 1785-1795
-
-
Pitkin, S.L.1
Maguire, J.J.2
Kuc, R.E.3
Davenport, A.P.4
-
68
-
-
34247876193
-
Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice
-
COI: 1:CAS:528:DC%2BD2sXlt1Cjtb4%3D, PID: 17359956
-
Zhong JC, Yu XY, Huang Y, Yung LM, Lau CW, Lin SG (2007) Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice. Cardiovasc Res 74(3):388–395. doi:10.1016/j.cardiores.2007.02.002
-
(2007)
Cardiovasc Res
, vol.74
, Issue.3
, pp. 388-395
-
-
Zhong, J.C.1
Yu, X.Y.2
Huang, Y.3
Yung, L.M.4
Lau, C.W.5
Lin, S.G.6
-
69
-
-
79551659095
-
Effect of apelin–apelin receptor system in postischaemic myocardial protection: a pharmacological postconditioning tool?
-
COI: 1:CAS:528:DC%2BC3MXht1yktrs%3D, PID: 20615122
-
Rastaldo R, Cappello S, Folino A, Losano G (2011) Effect of apelin–apelin receptor system in postischaemic myocardial protection: a pharmacological postconditioning tool? Antioxid Redox Signal 14(5):909–922. doi:10.1089/ars.2010.3355
-
(2011)
Antioxid Redox Signal
, vol.14
, Issue.5
, pp. 909-922
-
-
Rastaldo, R.1
Cappello, S.2
Folino, A.3
Losano, G.4
-
70
-
-
42649096311
-
The apelin-APJ system in heart failure: pathophysiologic relevance and therapeutic potential
-
COI: 1:CAS:528:DC%2BD1cXlsFOmsr4%3D, PID: 18272138
-
Japp AG, Newby DE (2008) The apelin-APJ system in heart failure: pathophysiologic relevance and therapeutic potential. Biochem Pharmacol 75(10):1882–1892. doi:10.1016/j.bcp.2007.12.015
-
(2008)
Biochem Pharmacol
, vol.75
, Issue.10
, pp. 1882-1892
-
-
Japp, A.G.1
Newby, D.E.2
-
71
-
-
44849144176
-
The apelinergic system: the role played in human physiology and pathology and potential therapeutic applications
-
PID: 18516406
-
Ladeiras-Lopes R, Ferreira-Martins J, Leite-Moreira AF (2008) The apelinergic system: the role played in human physiology and pathology and potential therapeutic applications. Arq Bras Cardiol 90(5):343–349
-
(2008)
Arq Bras Cardiol
, vol.90
, Issue.5
, pp. 343-349
-
-
Ladeiras-Lopes, R.1
Ferreira-Martins, J.2
Leite-Moreira, A.F.3
-
72
-
-
33745048094
-
Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells
-
COI: 1:CAS:528:DC%2BD28XksVGlsrk%3D, PID: 16556853
-
Hashimoto T, Kihara M, Ishida J, Imai N, Yoshida S, Toya Y, Fukamizu A, Kitamura H, Umemura S (2006) Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 26(6):1267–1272. doi:10.1161/01.ATV.0000218841.39828.91
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, Issue.6
, pp. 1267-1272
-
-
Hashimoto, T.1
Kihara, M.2
Ishida, J.3
Imai, N.4
Yoshida, S.5
Toya, Y.6
Fukamizu, A.7
Kitamura, H.8
Umemura, S.9
-
73
-
-
84891315119
-
+ channels in cerebral artery smooth muscle cells via a PI3-kinase dependent mechanism
-
PID: 24386141
-
+ channels in cerebral artery smooth muscle cells via a PI3-kinase dependent mechanism. PLoS One 8(12):e83051. doi:10.1371/journal.pone.0083051
-
(2013)
PLoS One
, vol.8
, Issue.12
, pp. 83051
-
-
Modgil, A.1
Guo, L.2
O’Rourke, S.T.3
Sun, C.4
-
74
-
-
0037032005
-
Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility
-
COI: 1:CAS:528:DC%2BD38XntVKktL0%3D, PID: 12215493
-
Szokodi I, Tavi P, Foldes G, Voutilainen-Myllyla S, Ilves M, Tokola H, Pikkarainen S, Piuhola J, Rysa J, Toth M, Ruskoaho H (2002) Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. Circ Res 91(5):434–440
-
(2002)
Circ Res
, vol.91
, Issue.5
, pp. 434-440
-
-
Szokodi, I.1
Tavi, P.2
Foldes, G.3
Voutilainen-Myllyla, S.4
Ilves, M.5
Tokola, H.6
Pikkarainen, S.7
Piuhola, J.8
Rysa, J.9
Toth, M.10
Ruskoaho, H.11
-
75
-
-
84898847077
-
Apelin increases cardiac contractility via protein kinase C epsilon- and extracellular signal-regulated kinase-dependent mechanisms
-
PID: 24695532
-
Perjes A, Skoumal R, Tenhunen O, Konyi A, Simon M, Horvath IG, Kerkela R, Ruskoaho H, Szokodi I (2014) Apelin increases cardiac contractility via protein kinase C epsilon- and extracellular signal-regulated kinase-dependent mechanisms. PLoS One 9(4):e93473. doi:10.1371/journal.pone.0093473
-
(2014)
PLoS One
, vol.9
, Issue.4
, pp. 93473
-
-
Perjes, A.1
Skoumal, R.2
Tenhunen, O.3
Konyi, A.4
Simon, M.5
Horvath, I.G.6
Kerkela, R.7
Ruskoaho, H.8
Szokodi, I.9
-
76
-
-
34249800363
-
Hypoxia inducible factor regulates the cardiac expression and secretion of apelin
-
COI: 1:CAS:528:DC%2BD2sXmsVWksrY%3D, PID: 17341685
-
Ronkainen VP, Ronkainen JJ, Hanninen SL, Leskinen H, Ruas JL, Pereira T, Poellinger L, Vuolteenaho O, Tavi P (2007) Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB J 21(8):1821–1830. doi:10.1096/fj.06-7294com
-
(2007)
FASEB J
, vol.21
, Issue.8
, pp. 1821-1830
-
-
Ronkainen, V.P.1
Ronkainen, J.J.2
Hanninen, S.L.3
Leskinen, H.4
Ruas, J.L.5
Pereira, T.6
Poellinger, L.7
Vuolteenaho, O.8
Tavi, P.9
-
77
-
-
33744816839
-
Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure
-
COI: 1:CAS:528:DC%2BD28Xls1eiu78%3D, PID: 16464638
-
Chong KS, Gardner RS, Morton JJ, Ashley EA, McDonagh TA (2006) Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure. Eur J Heart Fail 8(4):355–360. doi:10.1016/j.ejheart.2005.10.007
-
(2006)
Eur J Heart Fail
, vol.8
, Issue.4
, pp. 355-360
-
-
Chong, K.S.1
Gardner, R.S.2
Morton, J.J.3
Ashley, E.A.4
McDonagh, T.A.5
-
78
-
-
84887553992
-
Effects of acute intravenous infusion of apelin on left ventricular function in dogs with advanced heart failure
-
COI: 1:CAS:528:DC%2BC3sXhtVOrsLvJ
-
Wang M, Gupta RC, Rastogi S, Kohli S, Sabbah MS, Zhang K, Mohyi P, Hogie M, Fischer Y, Sabbah HN (2013) Effects of acute intravenous infusion of apelin on left ventricular function in dogs with advanced heart failure. J Cardiac Fail 19(7):509–516. doi:10.1016/j.cardfail.2013.05.004
-
(2013)
J Cardiac Fail
, vol.19
, Issue.7
, pp. 509-516
-
-
Wang, M.1
Gupta, R.C.2
Rastogi, S.3
Kohli, S.4
Sabbah, M.S.5
Zhang, K.6
Mohyi, P.7
Hogie, M.8
Fischer, Y.9
Sabbah, H.N.10
-
79
-
-
33751160364
-
Apelin increases contractility in failing cardiac muscle
-
COI: 1:CAS:528:DC%2BD28Xht1Ciu7bF, PID: 17055480
-
Dai T, Ramirez-Correa G, Gao WD (2006) Apelin increases contractility in failing cardiac muscle. Eur J Pharmacol 553(1–3):222–228. doi:10.1016/j.ejphar.2006.09.034
-
(2006)
Eur J Pharmacol
, vol.553
, Issue.1-3
, pp. 222-228
-
-
Dai, T.1
Ramirez-Correa, G.2
Gao, W.D.3
-
80
-
-
84897108860
-
Increased beta-adrenergic inotropy in ventricular myocardium from Trpm4−/− mice
-
COI: 1:CAS:528:DC%2BC2cXhvVSktbw%3D, PID: 24226423
-
Mathar I, Kecskes M, Van der Mieren G, Jacobs G, Camacho Londono JE, Uhl S, Flockerzi V, Voets T, Freichel M, Nilius B, Herijgers P, Vennekens R (2014) Increased beta-adrenergic inotropy in ventricular myocardium from Trpm4−/− mice. Circ Res 114(2):283–294. doi:10.1161/CIRCRESAHA.114.302835
-
(2014)
Circ Res
, vol.114
, Issue.2
, pp. 283-294
-
-
Mathar, I.1
Kecskes, M.2
Van der Mieren, G.3
Jacobs, G.4
Camacho Londono, J.E.5
Uhl, S.6
Flockerzi, V.7
Voets, T.8
Freichel, M.9
Nilius, B.10
Herijgers, P.11
Vennekens, R.12
-
81
-
-
0037049977
-
Cardiac excitation-contraction coupling
-
COI: 1:CAS:528:DC%2BD38Xms1Whsg%3D%3D, PID: 11805843
-
Bers DM (2002) Cardiac excitation-contraction coupling. Nature 415(6868):198–205. doi:10.1038/415198a
-
(2002)
Nature
, vol.415
, Issue.6868
, pp. 198-205
-
-
Bers, D.M.1
-
82
-
-
0034649268
-
Regulation of cardiac contraction and relaxation
-
COI: 1:STN:280:DC%2BD3M%2FkvVeitw%3D%3D, PID: 11080134
-
Katz AM, Lorell BH (2000) Regulation of cardiac contraction and relaxation. Circulation 102(20 Suppl 4):IV69–IV74
-
(2000)
Circulation
, vol.102
, pp. 69-74
-
-
Katz, A.M.1
Lorell, B.H.2
-
83
-
-
77955612761
-
Adrenergic signaling polymorphisms and their impact on cardiovascular disease
-
COI: 1:CAS:528:DC%2BC3cXhtVyku7rP, PID: 20664078
-
Dorn GW 2nd (2010) Adrenergic signaling polymorphisms and their impact on cardiovascular disease. Physiol Rev 90(3):1013–1062. doi:10.1152/physrev.00001.2010
-
(2010)
Physiol Rev
, vol.90
, Issue.3
, pp. 1013-1062
-
-
Dorn, G.W.1
-
84
-
-
49249099335
-
2+]i transient and contractions during twitches in isolated rat cardiac myocytes
-
COI: 1:CAS:528:DC%2BD1cXnsVaktr4%3D, PID: 18424641
-
2+]i transient and contractions during twitches in isolated rat cardiac myocytes. Am J Physiol Heart Circ Physiol 294(6):H2540–H2546. doi:10.1152/ajpheart.00046.2008
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
, Issue.6
, pp. 2540-2546
-
-
Wang, C.1
Du, J.F.2
Wu, F.3
Wang, H.C.4
-
85
-
-
0032749318
-
The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease
-
COI: 1:CAS:528:DyaK1MXntV2lt7c%3D, PID: 10532945
-
Karmazyn M, Gan XT, Humphreys RA, Yoshida H, Kusumoto K (1999) The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease. Circ Res 85(9):777–786
-
(1999)
Circ Res
, vol.85
, Issue.9
, pp. 777-786
-
-
Karmazyn, M.1
Gan, X.T.2
Humphreys, R.A.3
Yoshida, H.4
Kusumoto, K.5
-
86
-
-
0030051387
-
Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes
-
COI: 1:CAS:528:DyaK28XltVOh, PID: 8603511
-
Kojda G, Kottenberg K, Nix P, Schluter KD, Piper HM, Noack E (1996) Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes. Circ Res 78(1):91–101
-
(1996)
Circ Res
, vol.78
, Issue.1
, pp. 91-101
-
-
Kojda, G.1
Kottenberg, K.2
Nix, P.3
Schluter, K.D.4
Piper, H.M.5
Noack, E.6
-
87
-
-
34548247143
-
Nitric oxide and cardiac function
-
COI: 1:CAS:528:DC%2BD2sXpvFKmtLw%3D, PID: 17707439
-
Rastaldo R, Pagliaro P, Cappello S, Penna C, Mancardi D, Westerhof N, Losano G (2007) Nitric oxide and cardiac function. Life Sci 81(10):779–793. doi:10.1016/j.lfs.2007.07.019
-
(2007)
Life Sci
, vol.81
, Issue.10
, pp. 779-793
-
-
Rastaldo, R.1
Pagliaro, P.2
Cappello, S.3
Penna, C.4
Mancardi, D.5
Westerhof, N.6
Losano, G.7
-
88
-
-
29244481551
-
Apelin protects myocardial injury induced by isoproterenol in rats
-
COI: 1:CAS:528:DC%2BD2MXhtlCqtL3M, PID: 16278022
-
Jia YX, Pan CS, Zhang J, Geng B, Zhao J, Gerns H, Yang J, Chang JK, Tang CS, Qi YF (2006) Apelin protects myocardial injury induced by isoproterenol in rats. Regul Pept 133(1–3):147–154. doi:10.1016/j.regpep.2005.09.033
-
(2006)
Regul Pept
, vol.133
, Issue.1-3
, pp. 147-154
-
-
Jia, Y.X.1
Pan, C.S.2
Zhang, J.3
Geng, B.4
Zhao, J.5
Gerns, H.6
Yang, J.7
Chang, J.K.8
Tang, C.S.9
Qi, Y.F.10
-
90
-
-
1142297590
-
The first minutes of reperfusion: a window of opportunity for cardioprotection
-
COI: 1:CAS:528:DC%2BD2cXhtFWms7o%3D, PID: 14962469
-
Piper HM, Abdallah Y, Schafer C (2004) The first minutes of reperfusion: a window of opportunity for cardioprotection. Cardiovasc Res 61(3):365–371. doi:10.1016/j.cardiores.2003.12.012
-
(2004)
Cardiovasc Res
, vol.61
, Issue.3
, pp. 365-371
-
-
Piper, H.M.1
Abdallah, Y.2
Schafer, C.3
-
91
-
-
0023507184
-
Recombinant superoxide dismutase reduces oxygen free radical concentrations in reperfused myocardium
-
COI: 1:CAS:528:DyaL1cXkvFShsA%3D%3D, PID: 3680525
-
Zweier J, Rayburn B, Flaherty J, Weisfeldt M (1987) Recombinant superoxide dismutase reduces oxygen free radical concentrations in reperfused myocardium. J Clin Invest 80:1728–1734
-
(1987)
J Clin Invest
, vol.80
, pp. 1728-1734
-
-
Zweier, J.1
Rayburn, B.2
Flaherty, J.3
Weisfeldt, M.4
-
92
-
-
80053279944
-
Apelin-13 protects the heart against ischemia–reperfusion injury through inhibition of ER-dependent apoptotic pathways in a time-dependent fashion
-
COI: 1:CAS:528:DC%2BC3MXhtlertr%2FE, PID: 21803944
-
Tao J, Zhu W, Li Y, Xin P, Li J, Liu M, Li J, Redington AN, Wei M (2011) Apelin-13 protects the heart against ischemia–reperfusion injury through inhibition of ER-dependent apoptotic pathways in a time-dependent fashion. Am J Physiol Heart Circ Physiol 301(4):H1471–H1486. doi:10.1152/ajpheart.00097.2011
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, Issue.4
, pp. 1471-1486
-
-
Tao, J.1
Zhu, W.2
Li, Y.3
Xin, P.4
Li, J.5
Liu, M.6
Li, J.7
Redington, A.N.8
Wei, M.9
-
93
-
-
38349174739
-
Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase
-
COI: 1:CAS:528:DC%2BD1cXosFKntw%3D%3D, PID: 18022257
-
Kleinz MJ, Baxter GF (2008) Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase. Regul Pept 146(1–3):271–277. doi:10.1016/j.regpep.2007.10.002
-
(2008)
Regul Pept
, vol.146
, Issue.1-3
, pp. 271-277
-
-
Kleinz, M.J.1
Baxter, G.F.2
-
94
-
-
84900800981
-
Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion
-
COI: 1:CAS:528:DC%2BC2cXjsFyqu70%3D, PID: 24599747
-
Pisarenko OI, Lankin VZ, Konovalova GG, Serebryakova LI, Shulzhenko VS, Timoshin AA, Tskitishvili OV, Pelogeykina YA, Studneva IM (2014) Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion. Mol Cell Biochem 391(1–2):241–250. doi:10.1007/s11010-014-2008-4
-
(2014)
Mol Cell Biochem
, vol.391
, Issue.1-2
, pp. 241-250
-
-
Pisarenko, O.I.1
Lankin, V.Z.2
Konovalova, G.G.3
Serebryakova, L.I.4
Shulzhenko, V.S.5
Timoshin, A.A.6
Tskitishvili, O.V.7
Pelogeykina, Y.A.8
Studneva, I.M.9
-
95
-
-
67349152630
-
Apelin protects heart against ischemia/reperfusion injury in rat
-
COI: 1:CAS:528:DC%2BD1MXmsVSgt70%3D, PID: 19463748
-
Zeng XJ, Zhang LK, Wang HX, Lu LQ, Ma LQ, Tang CS (2009) Apelin protects heart against ischemia/reperfusion injury in rat. Peptides 30(6):1144–1152. doi:10.1016/j.peptides.2009.02.010
-
(2009)
Peptides
, vol.30
, Issue.6
, pp. 1144-1152
-
-
Zeng, X.J.1
Zhang, L.K.2
Wang, H.X.3
Lu, L.Q.4
Ma, L.Q.5
Tang, C.S.6
-
96
-
-
36849016827
-
Temporal changes in myocardial salvage kinases during reperfusion following ischemia: studies involving the cardioprotective adipocytokine apelin
-
COI: 1:CAS:528:DC%2BD2sXhtl2ks7zJ, PID: 17924178
-
Smith CC, Mocanu MM, Bowen J, Wynne AM, Simpkin JC, Dixon RA, Cooper MB, Yellon DM (2007) Temporal changes in myocardial salvage kinases during reperfusion following ischemia: studies involving the cardioprotective adipocytokine apelin. Cardiovasc Drugs Ther 21(6):409–414. doi:10.1007/s10557-007-6054-y
-
(2007)
Cardiovasc Drugs Ther
, vol.21
, Issue.6
, pp. 409-414
-
-
Smith, C.C.1
Mocanu, M.M.2
Bowen, J.3
Wynne, A.M.4
Simpkin, J.C.5
Dixon, R.A.6
Cooper, M.B.7
Yellon, D.M.8
-
97
-
-
34548044947
-
Preconditioning and postconditioning: united at reperfusion
-
COI: 1:CAS:528:DC%2BD2sXhtFSltLvI, PID: 17681609
-
Hausenloy DJ, Yellon DM (2007) Preconditioning and postconditioning: united at reperfusion. Pharmacol Ther 116(2):173–191. doi:10.1016/j.pharmthera.2007.06.005
-
(2007)
Pharmacol Ther
, vol.116
, Issue.2
, pp. 173-191
-
-
Hausenloy, D.J.1
Yellon, D.M.2
-
98
-
-
4444302049
-
Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice
-
COI: 1:CAS:528:DC%2BD2cXnslCrsLw%3D, PID: 15340063
-
Hamada H, Suzuki M, Yuasa S, Mimura N, Shinozuka N, Takada Y, Suzuki M, Nishino T, Nakaya H, Koseki H, Aoe T (2004) Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice. Mol Cell Biol 24(18):8007–8017. doi:10.1128/MCB.24.18.8007-8017.2004
-
(2004)
Mol Cell Biol
, vol.24
, Issue.18
, pp. 8007-8017
-
-
Hamada, H.1
Suzuki, M.2
Yuasa, S.3
Mimura, N.4
Shinozuka, N.5
Takada, Y.6
Suzuki, M.7
Nishino, T.8
Nakaya, H.9
Koseki, H.10
Aoe, T.11
-
99
-
-
33846805814
-
Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3-E1 via JNK and PI3-K/Akt signaling pathways
-
COI: 1:CAS:528:DC%2BD2sXhs1Cjtrg%3D, PID: 17109997
-
Tang SY, Xie H, Yuan LQ, Luo XH, Huang J, Cui RR, Zhou HD, Wu XP, Liao EY (2007) Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3-E1 via JNK and PI3-K/Akt signaling pathways. Peptides 28(3):708–718. doi:10.1016/j.peptides.2006.10.005
-
(2007)
Peptides
, vol.28
, Issue.3
, pp. 708-718
-
-
Tang, S.Y.1
Xie, H.2
Yuan, L.Q.3
Luo, X.H.4
Huang, J.5
Cui, R.R.6
Zhou, H.D.7
Wu, X.P.8
Liao, E.Y.9
-
100
-
-
84870507872
-
Apelin and pulmonary hypertension
-
COI: 1:CAS:528:DC%2BC3MXhs1Smt7rP, PID: 22140623
-
Andersen CU, Hilberg O, Mellemkjaer S, Nielsen-Kudsk JE, Simonsen U (2011) Apelin and pulmonary hypertension. Pulm Circ 1(3):334–346. doi:10.4103/2045-8932.87299
-
(2011)
Pulm Circ
, vol.1
, Issue.3
, pp. 334-346
-
-
Andersen, C.U.1
Hilberg, O.2
Mellemkjaer, S.3
Nielsen-Kudsk, J.E.4
Simonsen, U.5
-
101
-
-
80052348254
-
Disruption of PPARgamma/beta-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival
-
COI: 1:CAS:528:DC%2BC3MXhtFOhtr7P, PID: 21821917
-
Alastalo TP, Li M, de Jesus Perez V, Pham D, Sawada H, Wang JK, Koskenvuo M, Wang L, Freeman BA, Chang HY, Rabinovitch M (2011) Disruption of PPARgamma/beta-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival. J Clin Invest 121(9):3735–3746. doi:10.1172/JCI43382
-
(2011)
J Clin Invest
, vol.121
, Issue.9
, pp. 3735-3746
-
-
Alastalo, T.P.1
Li, M.2
de Jesus Perez, V.3
Pham, D.4
Sawada, H.5
Wang, J.K.6
Koskenvuo, M.7
Wang, L.8
Freeman, B.A.9
Chang, H.Y.10
Rabinovitch, M.11
-
102
-
-
78449303542
-
Apelin suppresses apoptosis of human vascular smooth muscle cells via APJ/PI3-K/Akt signaling pathways
-
COI: 1:CAS:528:DC%2BC3cXhtlaqtb7K, PID: 20495838
-
Cui RR, Mao DA, Yi L, Wang C, Zhang XX, Xie H, Wu XP, Liao XB, Zhou H, Meng JC, Yuan LQ, Liao EY (2010) Apelin suppresses apoptosis of human vascular smooth muscle cells via APJ/PI3-K/Akt signaling pathways. Amino Acids 39(5):1193–1200. doi:10.1007/s00726-010-0555-x
-
(2010)
Amino Acids
, vol.39
, Issue.5
, pp. 1193-1200
-
-
Cui, R.R.1
Mao, D.A.2
Yi, L.3
Wang, C.4
Zhang, X.X.5
Xie, H.6
Wu, X.P.7
Liao, X.B.8
Zhou, H.9
Meng, J.C.10
Yuan, L.Q.11
Liao, E.Y.12
-
103
-
-
84856202713
-
Protective effect of apelin on cultured rat bone marrow mesenchymal stem cells against apoptosis
-
COI: 1:CAS:528:DC%2BC38XltVagtbw%3D, PID: 22289418
-
Zeng X, Yu SP, Taylor T, Ogle M, Wei L (2012) Protective effect of apelin on cultured rat bone marrow mesenchymal stem cells against apoptosis. Stem cell Res 8(3):357–367. doi:10.1016/j.scr.2011.12.004
-
(2012)
Stem cell Res
, vol.8
, Issue.3
, pp. 357-367
-
-
Zeng, X.1
Yu, S.P.2
Taylor, T.3
Ogle, M.4
Wei, L.5
-
104
-
-
84865120187
-
Apelin-13 protects the brain against ischemic reperfusion injury and cerebral edema in a transient model of focal cerebral ischemia
-
COI: 1:CAS:528:DC%2BC38XhtFGhsLvO, PID: 22638858
-
Khaksari M, Aboutaleb N, Nasirinezhad F, Vakili A, Madjd Z (2012) Apelin-13 protects the brain against ischemic reperfusion injury and cerebral edema in a transient model of focal cerebral ischemia. J Mol Neurosci 48(1):201–208. doi:10.1007/s12031-012-9808-3
-
(2012)
J Mol Neurosci
, vol.48
, Issue.1
, pp. 201-208
-
-
Khaksari, M.1
Aboutaleb, N.2
Nasirinezhad, F.3
Vakili, A.4
Madjd, Z.5
-
105
-
-
84897953501
-
Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways
-
COI: 1:CAS:528:DC%2BC2cXmvVahtLc%3D, PID: 24686182
-
Yang Y, Zhang X, Cui H, Zhang C, Zhu C, Li L (2014) Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways. Neurosci Lett 568:44–49. doi:10.1016/j.neulet.2014.03.037
-
(2014)
Neurosci Lett
, vol.568
, pp. 44-49
-
-
Yang, Y.1
Zhang, X.2
Cui, H.3
Zhang, C.4
Zhu, C.5
Li, L.6
-
106
-
-
84885365424
-
Apelin-36, a potent peptide, protects against ischemic brain injury by activating the PI3K/Akt pathway
-
COI: 1:CAS:528:DC%2BC3sXhs12lt7vE, PID: 24083989
-
Gu Q, Zhai L, Feng X, Chen J, Miao Z, Ren L, Qian X, Yu J, Li Y, Xu X, Liu CF (2013) Apelin-36, a potent peptide, protects against ischemic brain injury by activating the PI3K/Akt pathway. Neurochem Int 63(6):535–540. doi:10.1016/j.neuint.2013.09.017
-
(2013)
Neurochem Int
, vol.63
, Issue.6
, pp. 535-540
-
-
Gu, Q.1
Zhai, L.2
Feng, X.3
Chen, J.4
Miao, Z.5
Ren, L.6
Qian, X.7
Yu, J.8
Li, Y.9
Xu, X.10
Liu, C.F.11
-
107
-
-
84884959084
-
Influence of fundectomy and intraperitoneal or intragastric administration of apelin on apoptosis, mitosis, and DNA repair enzyme OGG1,2 expression in adult rats gastrointestinal tract and pancreas
-
COI: 1:CAS:528:DC%2BC3sXhvVSms7rI, PID: 24101388
-
Antushevich H, Pawlina B, Kapica M, Krawczynska A, Herman AP, Kuwahara A, Kato I, Zabielski R (2013) Influence of fundectomy and intraperitoneal or intragastric administration of apelin on apoptosis, mitosis, and DNA repair enzyme OGG1,2 expression in adult rats gastrointestinal tract and pancreas. J Physiol Pharmacol 64(4):423–428
-
(2013)
J Physiol Pharmacol
, vol.64
, Issue.4
, pp. 423-428
-
-
Antushevich, H.1
Pawlina, B.2
Kapica, M.3
Krawczynska, A.4
Herman, A.P.5
Kuwahara, A.6
Kato, I.7
Zabielski, R.8
-
108
-
-
33845753359
-
Apelin suppresses apoptosis of human osteoblasts
-
COI: 1:CAS:528:DC%2BD28Xhtlalur3F, PID: 17136493
-
Xie H, Yuan LQ, Luo XH, Huang J, Cui RR, Guo LJ, Zhou HD, Wu XP, Liao EY (2007) Apelin suppresses apoptosis of human osteoblasts. Apoptosis 12(1):247–254. doi:10.1007/s10495-006-0489-7
-
(2007)
Apoptosis
, vol.12
, Issue.1
, pp. 247-254
-
-
Xie, H.1
Yuan, L.Q.2
Luo, X.H.3
Huang, J.4
Cui, R.R.5
Guo, L.J.6
Zhou, H.D.7
Wu, X.P.8
Liao, E.Y.9
-
109
-
-
70350608068
-
Apelin protects against cardiomyocyte apoptosis induced by glucose deprivation
-
COI: 1:CAS:528:DC%2BD1MXhsVWgsb%2FI, PID: 20079140
-
Zhang Z, Yu B, Tao GZ (2009) Apelin protects against cardiomyocyte apoptosis induced by glucose deprivation. Chin Med J 122(19):2360–2365
-
(2009)
Chin Med J
, vol.122
, Issue.19
, pp. 2360-2365
-
-
Zhang, Z.1
Yu, B.2
Tao, G.Z.3
-
110
-
-
84866426382
-
Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1
-
COI: 1:CAS:528:DC%2BC38XhtlygurvN, PID: 22028387
-
Pchejetski D, Foussal C, Alfarano C, Lairez O, Calise D, Guilbeau-Frugier C, Schaak S, Seguelas MH, Wanecq E, Valet P, Parini A, Kunduzova O (2012) Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1. Eur Heart J 33(18):2360–2369. doi:10.1093/eurheartj/ehr389
-
(2012)
Eur Heart J
, vol.33
, Issue.18
, pp. 2360-2369
-
-
Pchejetski, D.1
Foussal, C.2
Alfarano, C.3
Lairez, O.4
Calise, D.5
Guilbeau-Frugier, C.6
Schaak, S.7
Seguelas, M.H.8
Wanecq, E.9
Valet, P.10
Parini, A.11
Kunduzova, O.12
-
111
-
-
84255172428
-
Cardioprotective effect of apelin-13 on cardiac performance and remodeling in end-stage heart failure
-
COI: 1:CAS:528:DC%2BC38XhsV2jt7w%3D, PID: 22082814
-
Koguchi W, Kobayashi N, Takeshima H, Ishikawa M, Sugiyama F, Ishimitsu T (2012) Cardioprotective effect of apelin-13 on cardiac performance and remodeling in end-stage heart failure. Circ J 76(1):137–144
-
(2012)
Circ J
, vol.76
, Issue.1
, pp. 137-144
-
-
Koguchi, W.1
Kobayashi, N.2
Takeshima, H.3
Ishikawa, M.4
Sugiyama, F.5
Ishimitsu, T.6
-
112
-
-
0034705240
-
Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro
-
COI: 1:CAS:528:DC%2BD3cXks1Kmt74%3D, PID: 10864917
-
Siwik DA, Chang DL, Colucci WS (2000) Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro. Circ Res 86(12):1259–1265
-
(2000)
Circ Res
, vol.86
, Issue.12
, pp. 1259-1265
-
-
Siwik, D.A.1
Chang, D.L.2
Colucci, W.S.3
-
113
-
-
0034100147
-
Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases
-
COI: 1:CAS:528:DC%2BD3cXjvVWgtb4%3D, PID: 10699153
-
Kim S, Iwao H (2000) Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol Rev 52(1):11–34
-
(2000)
Pharmacol Rev
, vol.52
, Issue.1
, pp. 11-34
-
-
Kim, S.1
Iwao, H.2
-
114
-
-
79953208108
-
Myocardial fibrosis in response to Angiotensin II is preceded by the recruitment of mesenchymal progenitor cells
-
COI: 1:CAS:528:DC%2BC3MXjvFKgtb4%3D, PID: 21116240
-
Sopel MJ, Rosin NL, Lee TD, Legare JF (2011) Myocardial fibrosis in response to Angiotensin II is preceded by the recruitment of mesenchymal progenitor cells. Lab Invest 91(4):565–578. doi:10.1038/labinvest.2010.190
-
(2011)
Lab Invest
, vol.91
, Issue.4
, pp. 565-578
-
-
Sopel, M.J.1
Rosin, N.L.2
Lee, T.D.3
Legare, J.F.4
-
115
-
-
79955605472
-
Multiple facets of NF-kappaB in the heart: to be or not to NF-kappaB
-
COI: 1:CAS:528:DC%2BC3MXltl2gsrY%3D, PID: 21527742
-
Gordon JW, Shaw JA, Kirshenbaum LA (2011) Multiple facets of NF-kappaB in the heart: to be or not to NF-kappaB. Circ Res 108(9):1122–1132. doi:10.1161/CIRCRESAHA.110.226928
-
(2011)
Circ Res
, vol.108
, Issue.9
, pp. 1122-1132
-
-
Gordon, J.W.1
Shaw, J.A.2
Kirshenbaum, L.A.3
-
116
-
-
84879237561
-
Sustained cardiovascular actions of APJ agonism during renin-angiotensin system activation and in patients with heart failure
-
COI: 1:CAS:528:DC%2BC3sXhtFSntbvM, PID: 23519586
-
Barnes GD, Alam S, Carter G, Pedersen CM, Lee KM, Hubbard TJ, Veitch S, Jeong H, White A, Cruden NL, Huson L, Japp AG, Newby DE (2013) Sustained cardiovascular actions of APJ agonism during renin-angiotensin system activation and in patients with heart failure. Circ Heart Fail 6(3):482–491. doi:10.1161/CIRCHEARTFAILURE.111.000077
-
(2013)
Circ Heart Fail
, vol.6
, Issue.3
, pp. 482-491
-
-
Barnes, G.D.1
Alam, S.2
Carter, G.3
Pedersen, C.M.4
Lee, K.M.5
Hubbard, T.J.6
Veitch, S.7
Jeong, H.8
White, A.9
Cruden, N.L.10
Huson, L.11
Japp, A.G.12
Newby, D.E.13
-
117
-
-
36849008270
-
Apelin is a potent activator of tumour neoangiogenesis
-
COI: 1:CAS:528:DC%2BD2sXhtl2gur%2FN, PID: 17563744
-
Sorli SC, Le Gonidec S, Knibiehler B, Audigier Y (2007) Apelin is a potent activator of tumour neoangiogenesis. Oncogene 26(55):7692–7699. doi:10.1038/sj.onc.1210573
-
(2007)
Oncogene
, vol.26
, Issue.55
, pp. 7692-7699
-
-
Sorli, S.C.1
Le Gonidec, S.2
Knibiehler, B.3
Audigier, Y.4
-
118
-
-
84893275602
-
ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13
-
PID: 24374773
-
Yang L, Su T, Lv D, Xie F, Liu W, Cao J, Sheikh IA, Qin X, Li L, Chen L (2014) ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13. Acta Biochim Biophys Sin 46(2):100–111. doi:10.1093/abbs/gmt140
-
(2014)
Acta Biochim Biophys Sin
, vol.46
, Issue.2
, pp. 100-111
-
-
Yang, L.1
Su, T.2
Lv, D.3
Xie, F.4
Liu, W.5
Cao, J.6
Sheikh, I.A.7
Qin, X.8
Li, L.9
Chen, L.10
|