Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways

Neuroscience Letters

Volumn 568, Issue , 2014, Pages 44-49

  Yang, Yi ^a,b,c   Zhang, Xiangjian ^a,b,c   Cui, Haiying ^a,b,c   Zhang, Cong ^a,b,c   Zhu, Chunhua ^a,b,c   Li, Litao ^d  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Hebei Collaborative Innovation Center for Cardio cerebrovascular Disease   (China)

^c Hebei Key Laboratory for Neurology   (China)

^d HEBEI GENERAL HOSPITAL   (China)

Author keywords

Apelin 13; Cerebral ischemia reperfusion; ERK1 2; PI3K Akt

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; APELIN; APELIN 13; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; UNCLASSIFIED DRUG; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; APELIN-13 PEPTIDE; CHROMONE DERIVATIVE; FLAVONOID; MORPHOLINE DERIVATIVE; NEUROPROTECTIVE AGENT; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; LATERAL BRAIN VENTRICLE; MALE; MOUSE; NEUROLOGIC DISEASE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; REPERFUSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; BRAIN INFARCTION; DRUG EFFECTS; GENE EXPRESSION REGULATION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION;

ANIMALS; APOPTOSIS; BRAIN; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; CASPASE 3; CHROMONES; ENZYME ACTIVATION; FLAVONOIDS; GENE EXPRESSION REGULATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE, INBRED ICR; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MORPHOLINES; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 84897953501     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.03.037     Document Type: Article

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