Depletion of Foxp3+ Regulatory T Cells Promotes Profibrogenic Milieu of Cholestasis-Induced Liver Injury

Digestive Diseases and Sciences

Volumn 60, Issue 7, 2015, Pages 2009-2018

  Roh, Yoon Seok ^a,b,c   Park, Surim ^a,c   Lim, Chae Woong ^a,c   Kim, Bumseok ^a,c  

^a Chonbuk National University   (South Korea)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c Department of Veterinary Physiology   (South Korea)

Author keywords

Cholestasis; DEREG; Foxp3; Liver fibrosis; Treg

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CD8 ANTIGEN; CD9 ANTIGEN; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CD25+ T LYMPHOCYTE; CHOLESTASIS; CLINICAL ASSESSMENT; CONTROLLED STUDY; CYTOKINE PRODUCTION; FIBROGENESIS; GENE DELETION; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOCOMPETENT CELL; IN VIVO STUDY; LIVER FIBROSIS; LIVER INJURY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROFIBROGENIC MILIEU; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; T CELL DEPLETION; T LYMPHOCYTE; TH17 CELL; ANIMAL; BILE DUCT; C57BL MOUSE; CD8+ T LYMPHOCYTE; GENETICS; LIGATION; LIVER; LIVER CIRRHOSIS; METABOLISM; MUTATION; PATHOLOGY; PHYSIOLOGY; SURGERY;

ANIMALS; BILE DUCTS; CD8-POSITIVE T-LYMPHOCYTES; CHOLESTASIS; FORKHEAD TRANSCRIPTION FACTORS; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LIGATION; LIVER; LIVER CIRRHOSIS; MICE; MICE, INBRED C57BL; MUTATION; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84930821764     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-014-3438-2     Document Type: Article

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