Type 1 diabetes in biobreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire

Journal of Immunology

Volumn 185, Issue 4, 2010, Pages 2285-2294

  Van Den Brandt, Jens ^a,c   Fischer, Henrike J ^a   Walter, Lutz ^b   Hünig, Thomas ^c   Klöting, Ingrid ^d   Reichardt, Holger M ^a,c  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b GERMAN PRIMATE CENTER   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; GREEN FLUORESCENT PROTEIN; T LYMPHOCYTE RECEPTOR; GIMAP5 PROTEIN, RAT; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; LYMPHOCYTE ANTIGEN RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BIOBREEDING RAT; CELL ACTIVITY; CELL EXPANSION; CELL FUNCTION; CELL SELECTION; CELL TRANSFER; CONTROLLED STUDY; EFFECTOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GRAFT RECIPIENT; HAPLOTYPE; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RAT; REGULATORY T LYMPHOCYTE; SPECTRAL KARYOTYPING; TH17 CELL; TRANSGENIC RAT; ANIMAL; CELL LINE; GENETICS; HELPER CELL; HUMAN; IMMUNOLOGY; LYMPHOCYTE COUNT; LYMPHOCYTOPENIA; MALE; METABOLISM; MUTATION; PATHOLOGY; T LYMPHOCYTE; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; CELL LINE; DIABETES MELLITUS, TYPE 1; FEMALE; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEINS; HUMANS; INTERLEUKIN-17; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE COUNT; LYMPHOPENIA; MALE; MUTATION; RATS; RATS, INBRED BB; RATS, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

EID: 77956897470     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000462     Document Type: Article

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