-
2
-
-
0035908493
-
Blocking oncogenic Ras signaling for cancer therapy
-
Adjei AA. Blocking oncogenic Ras signaling for cancer therapy. J Natl Cancer Inst 2001; 93: 1062-74.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1062-1074
-
-
Adjei, A.A.1
-
3
-
-
0032975370
-
Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer
-
Graziano SL, Gamble GP, Newman NB, Abbott LZ, Rooney M, Mookherjee S, Lamb ML, Kohman LJ, Poiesz BJ. Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer. J Clin Oncol 1999; 17: 668-75.
-
(1999)
J Clin Oncol
, vol.17
, pp. 668-675
-
-
Graziano, S.L.1
Gamble, G.P.2
Newman, N.B.3
Abbott, L.Z.4
Rooney, M.5
Mookherjee, S.6
Lamb, M.L.7
Kohman, L.J.8
Poiesz, B.J.9
-
4
-
-
0033841640
-
Co-expression of epidermal growth factor receptor and transforming growth factor-α is independent of ras mutations in lung adenocarcinoma
-
Hsieh ET, Shepherd FA, Tsao MS. Co-expression of epidermal growth factor receptor and transforming growth factor-α is independent of ras mutations in lung adenocarcinoma. Lung Cancer 2000; 29: 151-7.
-
(2000)
Lung Cancer
, vol.29
, pp. 151-157
-
-
Hsieh, E.T.1
Shepherd, F.A.2
Tsao, M.S.3
-
5
-
-
18744434862
-
Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression
-
Ohsaki Y, Tanno S, Fujita Y, Toyoshima E, Fujiuchi S, Nishigaki Y, Ishida S, Nagase A, Miyokawa N, Hirata S, et al. Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression. Oncol Rep 2000; 7: 603-7.
-
(2000)
Oncol Rep
, vol.7
, pp. 603-607
-
-
Ohsaki, Y.1
Tanno, S.2
Fujita, Y.3
Toyoshima, E.4
Fujiuchi, S.5
Nishigaki, Y.6
Ishida, S.7
Nagase, A.8
Miyokawa, N.9
Hirata, S.10
-
6
-
-
0032547380
-
Progress in understanding the molecular pathogenesis of human lung cancer
-
Sekido Y, Fong KM, Minna JD. Progress in understanding the molecular pathogenesis of human lung cancer. Biochim Biophys Acta 1998; 1378: F21-59.
-
(1998)
Biochim Biophys Acta
, vol.1378
, pp. F21-F59
-
-
Sekido, Y.1
Fong, K.M.2
Minna, J.D.3
-
7
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14: 1837-51.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
9
-
-
0037130449
-
Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
-
Taniguchi K, Roberts LR, Aderca IN, Dong X, Qian C, Murphy LM, Nagorney DM, Burgart LJ, Roche PC, Smith DI, et al. Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002; 21: 4863-71.
-
(2002)
Oncogene
, vol.21
, pp. 4863-4871
-
-
Taniguchi, K.1
Roberts, L.R.2
Aderca, I.N.3
Dong, X.4
Qian, C.5
Murphy, L.M.6
Nagorney, D.M.7
Burgart, L.J.8
Roche, P.C.9
Smith, D.I.10
-
10
-
-
3142590865
-
Wnt signaling and breast cancer
-
Howe LR, Brown AM. Wnt signaling and breast cancer. Cancer Biol Ther 2004; 3: 36-41.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 36-41
-
-
Howe, L.R.1
Brown, A.M.2
-
11
-
-
0032529234
-
Beta-catenin mutation in carcinoma of the uterine endometrium
-
Fukuchi T, Sakamoto M, Tsuda H, Maruyama K, Nozawa S, Hirohashi S. Beta-catenin mutation in carcinoma of the uterine endometrium. Cancer Res 1998; 58: 3526-8.
-
(1998)
Cancer Res
, vol.58
, pp. 3526-3528
-
-
Fukuchi, T.1
Sakamoto, M.2
Tsuda, H.3
Maruyama, K.4
Nozawa, S.5
Hirohashi, S.6
-
12
-
-
0033731796
-
Altered HOX and WNT7A expression in human lung cancer
-
Calvo R, West J, Franklin W, Erickson P, Bemis L, Li E, Helfrich B, Bunn P, Roche J, Brambilla E, et al. Altered HOX and WNT7A expression in human lung cancer. Proc Natl Acad Sci U S A 2000; 97: 12776-81.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12776-12781
-
-
Calvo, R.1
West, J.2
Franklin, W.3
Erickson, P.4
Bemis, L.5
Li, E.6
Helfrich, B.7
Bunn, P.8
Roche, J.9
Brambilla, E.10
-
13
-
-
21244440303
-
Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation
-
Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, Hammond M, Van Scoyk M, Acosta H, Mirus J, Barry N, et al. Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation. J Biol Chem 2005; 280: 19625-34.
-
(2005)
J Biol Chem
, vol.280
, pp. 19625-19634
-
-
Winn, R.A.1
Marek, L.2
Han, S.Y.3
Rodriguez, K.4
Rodriguez, N.5
Hammond, M.6
Van Scoyk, M.7
Acosta, H.8
Mirus, J.9
Barry, N.10
-
14
-
-
33748754006
-
Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gamma
-
Winn RA, Van Scoyk M, Hammond M, Rodriguez K, Crossno JT Jr, Heasley LE, Nemenoff RA. Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gamma. J Biol Chem 2006; 281: 26943-50.
-
(2006)
J Biol Chem
, vol.281
, pp. 26943-26950
-
-
Winn, R.A.1
Van Scoyk, M.2
Hammond, M.3
Rodriguez, K.4
Crossno, J.T.5
Heasley, L.E.6
Nemenoff, R.A.7
-
15
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002; 3: 415-28.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
16
-
-
0029843950
-
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myöhänen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996; 93: 9821-6.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myöhänen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
17
-
-
0037742210
-
Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays
-
Sato N, Fukushima N, Maitra A, Matsubayashi H, Yeo CJ, Cameron JL, Hruban RH, Goggins M. Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. Cancer Res 2003; 63: 3735-42.
-
(2003)
Cancer Res
, vol.63
, pp. 3735-3742
-
-
Sato, N.1
Fukushima, N.2
Maitra, A.3
Matsubayashi, H.4
Yeo, C.J.5
Cameron, J.L.6
Hruban, R.H.7
Goggins, M.8
-
18
-
-
33845667580
-
Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours
-
Lindberg D, Akerström G, Westin G. Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours. Clin Endocrinol (Oxf) 2007; 66: 110-4.
-
(2007)
Clin Endocrinol (Oxf)
, vol.66
, pp. 110-114
-
-
Lindberg, D.1
Akerström, G.2
Westin, G.3
-
19
-
-
0036186078
-
Pathology of lung cancer
-
Travis WD. Pathology of lung cancer. Clin Chest Med 2002; 23: 65-81, viii.
-
(2002)
Clin Chest Med
, vol.23
-
-
Travis, W.D.1
-
20
-
-
0033079605
-
The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
-
Christofori G, Semb H. The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene. Trends Biochem Sci 1999; 24: 73-6.
-
(1999)
Trends Biochem Sci
, vol.24
, pp. 73-76
-
-
Christofori, G.1
Semb, H.2
-
21
-
-
0037093230
-
High-throughput tissue microarray analysis used to evaluate biology and prognostic significance of the E-cadherin pathway in non-small-cell lung cancer
-
Bremnes RM, Veve R, Gabrielson E, Hirsch FR, Baron A, Bemis L, Gemmill RM, Drabkin HA, Franklin WA. High-throughput tissue microarray analysis used to evaluate biology and prognostic significance of the E-cadherin pathway in non-small-cell lung cancer. J Clin Oncol 2002; 20: 2417-28.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2417-2428
-
-
Bremnes, R.M.1
Veve, R.2
Gabrielson, E.3
Hirsch, F.R.4
Baron, A.5
Bemis, L.6
Gemmill, R.M.7
Drabkin, H.A.8
Franklin, W.A.9
-
22
-
-
0032466624
-
Influence of E-cadherin dysfunction upon local invasion and metastasis in non-small cell lung cancer
-
Shibanuma H, Hirano T, Tsuji K, Wu Q, Shrestha B, Konaka C, Ebihara Y, Kato H. Influence of E-cadherin dysfunction upon local invasion and metastasis in non-small cell lung cancer. Lung Cancer 1998; 22: 85-95.
-
(1998)
Lung Cancer
, vol.22
, pp. 85-95
-
-
Shibanuma, H.1
Hirano, T.2
Tsuji, K.3
Wu, Q.4
Shrestha, B.5
Konaka, C.6
Ebihara, Y.7
Kato, H.8
-
23
-
-
0031968330
-
Reduced E-cadherin expression is associated with increased lymph node metastasis and unfavorable prognosis in non-small cell lung cancer
-
Sulzer MA, Leers MP, van Noord JA, Bollen EC, Theunissen PH. Reduced E-cadherin expression is associated with increased lymph node metastasis and unfavorable prognosis in non-small cell lung cancer. Am J Respir Crit Care Med 1998; 157: 1319-23.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1319-1323
-
-
Sulzer, M.A.1
Leers, M.P.2
van Noord, J.A.3
Bollen, E.C.4
Theunissen, P.H.5
-
24
-
-
0032431279
-
The expression of beta-catenin in non-small-cell lung cancer: a clinicopathological study
-
Retera JM, Leers MP, Sulzer MA, Theunissen PH. The expression of beta-catenin in non-small-cell lung cancer: a clinicopathological study. J Clin Pathol 1998; 51: 891-4.
-
(1998)
J Clin Pathol
, vol.51
, pp. 891-894
-
-
Retera, J.M.1
Leers, M.P.2
Sulzer, M.A.3
Theunissen, P.H.4
-
25
-
-
0031950315
-
Reduced expression of plakoglobin indicates an unfavorable prognosis in subsets of patients with non-small-cell lung cancer
-
Pantel K, Passlick B, Vogt J, Stosiek P, Angstwurm M, Seen-Hibler R, Häussinger K, Thetter O, Izbicki JR, Riethmüller G. Reduced expression of plakoglobin indicates an unfavorable prognosis in subsets of patients with non-small-cell lung cancer. J Clin Oncol 1998; 16: 1407-13.
-
(1998)
J Clin Oncol
, vol.16
, pp. 1407-1413
-
-
Pantel, K.1
Passlick, B.2
Vogt, J.3
Stosiek, P.4
Angstwurm, M.5
Seen-Hibler, R.6
Häussinger, K.7
Thetter, O.8
Izbicki, J.R.9
Riethmüller, G.10
-
26
-
-
0032990566
-
Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer
-
Smythe WR, Williams JP, Wheelock MJ, Johnson KR, Kaiser LR, Albelda SM. Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer. Lung Cancer 1999; 24: 157-68.
-
(1999)
Lung Cancer
, vol.24
, pp. 157-168
-
-
Smythe, W.R.1
Williams, J.P.2
Wheelock, M.J.3
Johnson, K.R.4
Kaiser, L.R.5
Albelda, S.M.6
-
27
-
-
0034996556
-
Reduced expression of α-catenin, β-catenin, and γ-catenin is associated with high cell proliferative activity and poor differentiation in non-small cell lung cancer
-
Pirinen RT, Hirvikoski P, Johansson RT, Hollmén S, Kosma VM. Reduced expression of α-catenin, β-catenin, and γ-catenin is associated with high cell proliferative activity and poor differentiation in non-small cell lung cancer. J Clin Pathol 2001; 54: 391-5.
-
(2001)
J Clin Pathol
, vol.54
, pp. 391-395
-
-
Pirinen, R.T.1
Hirvikoski, P.2
Johansson, R.T.3
Hollmén, S.4
Kosma, V.M.5
-
28
-
-
0033083047
-
Reduced expression of the cell cycle inhibitor p27Kip1 in non-small cell lung carcinoma: a prognostic factor independent of Ras
-
Catzavelos C, Tsao MS, DeBoer G, Bhattacharya N, Shepherd FA, Slingerland JM. Reduced expression of the cell cycle inhibitor p27Kip1 in non-small cell lung carcinoma: a prognostic factor independent of Ras. Cancer Res 1999; 59: 684-8.
-
(1999)
Cancer Res
, vol.59
, pp. 684-688
-
-
Catzavelos, C.1
Tsao, M.S.2
DeBoer, G.3
Bhattacharya, N.4
Shepherd, F.A.5
Slingerland, J.M.6
-
29
-
-
0032832873
-
Prognostic value of nucleolar protein p120 in patients with resected lung adenocarcinoma
-
Sato G, Saijo Y, Uchiyama B, Kumano N, Sugawara S, Fujimura S, Sato M, Sagawa M, Ohkuda K, Koike K, et al. Prognostic value of nucleolar protein p120 in patients with resected lung adenocarcinoma. J Clin Oncol 1999; 17: 2721-7.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2721-2727
-
-
Sato, G.1
Saijo, Y.2
Uchiyama, B.3
Kumano, N.4
Sugawara, S.5
Fujimura, S.6
Sato, M.7
Sagawa, M.8
Ohkuda, K.9
Koike, K.10
-
30
-
-
0032510494
-
A causal role for E-cadherin in the transition from adenoma to carcinoma
-
Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998; 392: 190-3.
-
(1998)
Nature
, vol.392
, pp. 190-193
-
-
Perl, A.K.1
Wilgenbus, P.2
Dahl, U.3
Semb, H.4
Christofori, G.5
-
31
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2: 442-54.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
32
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, Pérez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG, Portillo F, Nieto MA. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000; 2: 76-83.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
Pérez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
del Barrio, M.G.6
Portillo, F.7
Nieto, M.A.8
-
33
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A, Weinberg RA. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004; 117: 927-39.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
34
-
-
0030771851
-
Accumulation of Armadillo induced by Wingless, Dishevelled, and dominant-negative Zeste-White 3 leads to elevated DE-cadherin in Drosophila clone 8 wing disc cells
-
Yanagawa S, Lee JS, Haruna T, Oda H, Uemura T, Takeichi M, Ishimoto A. Accumulation of Armadillo induced by Wingless, Dishevelled, and dominant-negative Zeste-White 3 leads to elevated DE-cadherin in Drosophila clone 8 wing disc cells. J Biol Chem 1997; 272: 25243-51.
-
(1997)
J Biol Chem
, vol.272
, pp. 25243-25251
-
-
Yanagawa, S.1
Lee, J.S.2
Haruna, T.3
Oda, H.4
Uemura, T.5
Takeichi, M.6
Ishimoto, A.7
-
35
-
-
0345343608
-
Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
-
Huber O, Korn R, McLaughlin J, Ohsugi M, Herrmann BG, Kemler R. Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech Dev 1996; 59: 3-10.
-
(1996)
Mech Dev
, vol.59
, pp. 3-10
-
-
Huber, O.1
Korn, R.2
McLaughlin, J.3
Ohsugi, M.4
Herrmann, B.G.5
Kemler, R.6
-
36
-
-
0032033344
-
Xenopus cadherin-11 (Xcadherin-11) expression requires the Wg/Wnt signal
-
Hadeball B, Borchers A, Wedlich D. Xenopus cadherin-11 (Xcadherin-11) expression requires the Wg/Wnt signal. Mech Dev 1998; 72: 101-13.
-
(1998)
Mech Dev
, vol.72
, pp. 101-113
-
-
Hadeball, B.1
Borchers, A.2
Wedlich, D.3
-
37
-
-
0042337389
-
WNT7a induces E-cadherin in lung cancer cells
-
Ohira T, Gemmill RM, Ferguson K, Kusy S, Roche J, Brambilla E, Zeng C, Baron A, Bemis L, Erickson P, et al. WNT7a induces E-cadherin in lung cancer cells. Proc Natl Acad Sci U S A 2003; 100: 10429-34.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10429-10434
-
-
Ohira, T.1
Gemmill, R.M.2
Ferguson, K.3
Kusy, S.4
Roche, J.5
Brambilla, E.6
Zeng, C.7
Baron, A.8
Bemis, L.9
Erickson, P.10
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