-
1
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
Tanzi, R.E.; Bertram, L. Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective. Cell 2005, 120, 545-555.
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
2
-
-
0038308843
-
The magnitude of dementia occurrence in the world
-
Wimo, A.; Winblad, B.; Aguero-Torres, H.; von Strauss, E. The magnitude of dementia occurrence in the world. Alzheimer Dis. Assoc. Disord. 2003, 17, 63-67.
-
(2003)
Alzheimer Dis. Assoc. Disord
, vol.17
, pp. 63-67
-
-
Wimo, A.1
Winblad, B.2
Aguero-Torres, H.3
von Strauss, E.4
-
3
-
-
84865401658
-
Genetics and epigenetics of Alzheimer's disease
-
Alagiakrishnan, K.; Gill, S.S.; Fagarasanu, A. Genetics and epigenetics of Alzheimer's disease. Postgrad. Med. J. 2012, 88, 522-529.
-
(2012)
Postgrad. Med. J
, vol.88
, pp. 522-529
-
-
Alagiakrishnan, K.1
Gill, S.S.2
Fagarasanu, A.3
-
4
-
-
33746310315
-
Alzheimer's disease
-
Blennow, K.; de Leon, M.J.; Zetterberg, H. Alzheimer's disease. Lancet 2006, 368, 387-403.
-
(2006)
Lancet
, vol.368
, pp. 387-403
-
-
Blennow, K.1
de Leon, M.J.2
Zetterberg, H.3
-
5
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy, J.; Selkoe, D.J. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 2002, 297, 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
6
-
-
0032910197
-
The cholinergic hypothesis of Alzheimer's disease: A review of progress
-
Francis, P.T.; Palmer A.M.; Snape, M.; Wilcock, G.K. The cholinergic hypothesis of Alzheimer's disease: A review of progress. J. Neurol. Neurosurg. 1999, 66, 137-147.
-
(1999)
J. Neurol. Neurosurg
, vol.66
, pp. 137-147
-
-
Francis, P.T.1
Palmer, A.M.2
Snape, M.3
Wilcock, G.K.4
-
7
-
-
12344254945
-
Evaluation of cholinergic markers in Alzheimer's disease and in a model of cholinergic deficit
-
Gil-Bea, F.J.; García-Alloza, M.; Domínguez, J.; Marcos, B.; Ramírez, M.J. Evaluation of cholinergic markers in Alzheimer's disease and in a model of cholinergic deficit. Neurosci. Lett. 2005, 375, 37-41.
-
(2005)
Neurosci. Lett
, vol.375
, pp. 37-41
-
-
Gil-Bea, F.J.1
García-Alloza, M.2
Domínguez, J.3
Marcos, B.4
Ramírez, M.J.5
-
8
-
-
44049102976
-
Current and future therapy in Alzheimer's disease
-
Van Marum, R.J. Current and future therapy in Alzheimer's disease. Fundam. Clin. Pharmacol. 2008, 22, 265-274.
-
(2008)
Fundam. Clin. Pharmacol
, vol.22
, pp. 265-274
-
-
van Marum, R.J.1
-
9
-
-
31144450053
-
Current pharmacotherapy for Alzheimer's disease
-
Lleó, A; Greenberg, S.M.; Growdon, J.H. Current pharmacotherapy for Alzheimer's disease. Annu. Rev. Med. 2006, 57, 513-533.
-
(2006)
Annu. Rev. Med
, vol.57
, pp. 513-533
-
-
Lleó, A.1
Greenberg, S.M.2
Growdon, J.H.3
-
10
-
-
79958274796
-
The role of phytochemicals in the treatment and prevention of dementia
-
Howes, M.J.; Perry, E. The role of phytochemicals in the treatment and prevention of dementia. Drugs Aging 2011, 28, 439-468.
-
(2011)
Drugs Aging
, vol.28
, pp. 439-468
-
-
Howes, M.J.1
Perry, E.2
-
11
-
-
84880262652
-
Attenuation of β-amyloid-induced oxidative cell death by sulforaphane via activation of NF-E2-related factor 2
-
doi:10.1155/2013/313510
-
Lee, C.; Park, G.H.; Lee, S.R.; Jang, J.H. Attenuation of β-amyloid-induced oxidative cell death by sulforaphane via activation of NF-E2-related factor 2. Oxid. Med. Cell. Longev. 2013, doi:10.1155/2013/313510.
-
(2013)
Oxid. Med. Cell. Longev
-
-
Lee, C.1
Park, G.H.2
Lee, S.R.3
Jang, J.H.4
-
12
-
-
84874159254
-
Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model
-
Kim, H.V.; Kim, H.Y.; Ehrlich, H.Y.; Choi, S.Y.; Kim, D.J.; Kim, Y. Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model. Amyloid 2013, 20, 7-12.
-
(2013)
Amyloid
, vol.20
, pp. 7-12
-
-
Kim, H.V.1
Kim, H.Y.2
Ehrlich, H.Y.3
Choi, S.Y.4
Kim, D.J.5
Kim, Y.6
-
13
-
-
79960692625
-
Combined administration of D-galactose and aluminium induces Alzheimer-like lesions in brain
-
Xiao, F.; Li, X.G.; Zhang, X.Y.; Hou, J.D.; Lin, L.F.; Gao, Q.; Luo, H.M. Combined administration of D-galactose and aluminium induces Alzheimer-like lesions in brain. Neurosci. Bull. 2011, 27, 143-155.
-
(2011)
Neurosci. Bull
, vol.27
, pp. 143-155
-
-
Xiao, F.1
Li, X.G.2
Zhang, X.Y.3
Hou, J.D.4
Lin, L.F.5
Gao, Q.6
Luo, H.M.7
-
14
-
-
84925623527
-
Sulforaphane ameliorates neurobehavioral deficits and protects the brain from amyloid β deposits and peroxidation in mice with Alzheimer-like lesions
-
doi:10.1177/1533317514542645
-
Zhang, R.; Miao, Q.W.; Zhu, C.X.; Zhao, Y.; Liu, L.; Yang, J.; An, L. Sulforaphane ameliorates neurobehavioral deficits and protects the brain from amyloid β deposits and peroxidation in mice with Alzheimer-like lesions. Am. J. Alzheimer's Dis. Other Demen. 2014, doi:10.1177/1533317514542645.
-
(2014)
Am. J. Alzheimer's Dis. Other Demen
-
-
Zhang, R.1
Miao, Q.W.2
Zhu, C.X.3
Zhao, Y.4
Liu, L.5
Yang, J.6
An, L.7
-
15
-
-
84867610248
-
Behavioral effects of Rho GTPase modulation in a model of Alzheimer's disease
-
Musilli, M.; Nicolia, V.; Borrelli, S.; Scarpa, S.; Diana, G. Behavioral effects of Rho GTPase modulation in a model of Alzheimer's disease. Behav. Brain Res. 2013, 237, 223-229.
-
(2013)
Behav. Brain Res
, vol.237
, pp. 223-229
-
-
Musilli, M.1
Nicolia, V.2
Borrelli, S.3
Scarpa, S.4
Diana, G.5
-
16
-
-
0020072221
-
Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain
-
Whitehouse, P.J.; Price, D.L.; Struble, R.G.; Clark, A.W.; Coyle, J.T.; Delon, M.R. Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain. Science 1982, 215, 1237-1239.
-
(1982)
Science
, vol.215
, pp. 1237-1239
-
-
Whitehouse, P.J.1
Price, D.L.2
Struble, R.G.3
Clark, A.W.4
Coyle, J.T.5
Delon, M.R.6
-
17
-
-
0029984778
-
Cholinergic-dependent plateau potential in hippocampal CA1 pyramidal neurons
-
Fraser, D.D.; MacVicar, B.A. Cholinergic-dependent plateau potential in hippocampal CA1 pyramidal neurons. J. Neurosci. 1996, 16, 4113-4128.
-
(1996)
J. Neurosci
, vol.16
, pp. 4113-4128
-
-
Fraser, D.D.1
Macvicar, B.A.2
-
18
-
-
61849127257
-
Recombinant human NGF-loaded microspheres promote survival of basal forebrain cholinergic neurons and improve memory impairments of spatial learning in the rat model of Alzheimer's disease with fimbria-fornix lesion
-
Gu, H.; Long, D.; Song, C.; Li, X. Recombinant human NGF-loaded microspheres promote survival of basal forebrain cholinergic neurons and improve memory impairments of spatial learning in the rat model of Alzheimer's disease with fimbria-fornix lesion. Neurosci. Lett. 2009, 453, 204-209.
-
(2009)
Neurosci. Lett
, vol.453
, pp. 204-209
-
-
Gu, H.1
Long, D.2
Song, C.3
Li, X.4
-
19
-
-
84868568082
-
Expression of APP, BACE1, AChE and ChAT in an AD model in rats and the effect of donepezil hydrochloride treatment
-
Li, Q.; Chen, M.; Liu, H.; Yang, L.; Yang, G. Expression of APP, BACE1, AChE and ChAT in an AD model in rats and the effect of donepezil hydrochloride treatment. Mol. Med. Rep. 2012, 6, 1450-1455.
-
(2012)
Mol. Med. Rep
, vol.6
, pp. 1450-1455
-
-
Li, Q.1
Chen, M.2
Liu, H.3
Yang, L.4
Yang, G.5
-
20
-
-
0037430760
-
The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo
-
Scali, C.; Giovannini, M.G.; Prosperi, C.; Bellucci, A.; Pepeu, G.; Casamenti, F. The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo. Neuroscience 2003, 117, 909-919.
-
(2003)
Neuroscience
, vol.117
, pp. 909-919
-
-
Scali, C.1
Giovannini, M.G.2
Prosperi, C.3
Bellucci, A.4
Pepeu, G.5
Casamenti, F.6
-
21
-
-
84940286956
-
The impact of Boschiakia Rossica extract on the Ach, ChAT and AChE of AD rats
-
(In Chinese)
-
Zhou, L.; Zhu, S.; Wang L. The impact of Boschiakia Rossica extract on the Ach, ChAT and AChE of AD rats. Chin. Arch. Trad. Chin. Med. 2009, 27, 1874-1876. (In Chinese)
-
(2009)
Chin. Arch. Trad. Chin. Med
, vol.27
, pp. 1874-1876
-
-
Zhou, L.1
Zhu, S.2
Wang, L.3
-
22
-
-
0141818332
-
Cholinergic function and Alzheimer's disease
-
Giacobini, E. Cholinergic function and Alzheimer's disease. Int. J. Geriatr. Psychiatry 2003, 18, S1-S5.
-
(2003)
Int. J. Geriatr. Psychiatry
, vol.18
-
-
Giacobini, E.1
-
23
-
-
0036156958
-
Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment
-
DeKosky, S.T.; Ikonomovic, M.D.; Styren, S.D.; Beckett, L.; Wisniewski, S.; Bennett, D.A.; Cochran, E.J.; Kordower, J.H.; Mufson, E.J. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann. Neurol. 2002, 51, 145-155.
-
(2002)
Ann. Neurol
, vol.51
, pp. 145-155
-
-
Dekosky, S.T.1
Ikonomovic, M.D.2
Styren, S.D.3
Beckett, L.4
Wisniewski, S.5
Bennett, D.A.6
Cochran, E.J.7
Kordower, J.H.8
Mufson, E.J.9
-
24
-
-
84887612717
-
Sulforaphane: Translational research from laboratory bench to clinic
-
Houghton, C.A.; Fassett, R.G.; Coombes, J.S. Sulforaphane: Translational research from laboratory bench to clinic. Nutr. Rev. 2013, 71, 709-726.
-
(2013)
Nutr. Rev
, vol.71
, pp. 709-726
-
-
Houghton, C.A.1
Fassett, R.G.2
Coombes, J.S.3
-
25
-
-
84884493497
-
Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke
-
Alfieri, A.; Srivastava, S.; Siow, R.C.; Cash, D.; Modo, M.; Duchen, M.R.; Fraser, P.A.; Williams, S.C.; Mann, G.E. Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke. Free Radic. Biol. Med. 2013, 65, 1012-1022.
-
(2013)
Free Radic. Biol. Med
, vol.65
, pp. 1012-1022
-
-
Alfieri, A.1
Srivastava, S.2
Siow, R.C.3
Cash, D.4
Modo, M.5
Duchen, M.R.6
Fraser, P.A.7
Williams, S.C.8
Mann, G.E.9
-
26
-
-
66949123850
-
Sulforaphane improves cognitive function administered following traumatic brain injury
-
Dash, P.K.; Zhao, J.; Orsi, S.A.; Zhang, M.; Moore, A.N. Sulforaphane improves cognitive function administered following traumatic brain injury. Neurosci. Lett. 2009, 460, 103-107.
-
(2009)
Neurosci. Lett
, vol.460
, pp. 103-107
-
-
Dash, P.K.1
Zhao, J.2
Orsi, S.A.3
Zhang, M.4
Moore, A.N.5
-
27
-
-
84876376158
-
Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease
-
Morroni, F.; Tarozzi, A.; Sita, G.; Bolondi, C.; Zolezzi-Moraga, J.M.; Cantelli-Forti, G.; Hrelia, P. Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease. Neurotoxicology 2013, 36, 63-71.
-
(2013)
Neurotoxicology
, vol.36
, pp. 63-71
-
-
Morroni, F.1
Tarozzi, A.2
Sita, G.3
Bolondi, C.4
Zolezzi-Moraga, J.M.5
Cantelli-Forti, G.6
Hrelia, P.7
-
28
-
-
84871442704
-
Sulforaphane protects primary cultures of cortical neurons against injury induced by oxygen-glucose deprivation/reoxygenation via antiapoptosis
-
Wu, X.; Zhao, J.; Yu, S.; Chen, Y.; Wu, J.; Zhao, Y. Sulforaphane protects primary cultures of cortical neurons against injury induced by oxygen-glucose deprivation/reoxygenation via antiapoptosis. Neurosci. Bull. 2012, 28, 509-516.
-
(2012)
Neurosci. Bull
, vol.28
, pp. 509-516
-
-
Wu, X.1
Zhao, J.2
Yu, S.3
Chen, Y.4
Wu, J.5
Zhao, Y.6
-
29
-
-
84863338153
-
Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury
-
Wang, X.; de Rivero Vaccari, J.P.; Wang, H.; Diaz, P.; German, R.; Marcillo, A.E.; Keane, R.W. Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury. J. Neurotrauma 2012, 29, 936-945.
-
(2012)
J. Neurotrauma
, vol.29
, pp. 936-945
-
-
Wang, X.1
de Rivero Vaccari, J.P.2
Wang, H.3
Diaz, P.4
German, R.5
Marcillo, A.E.6
Keane, R.W.7
-
30
-
-
0242317367
-
Glia as neural progenitor cells
-
Goldman, S. Glia as neural progenitor cells. Trends Neurosci. 2003, 26, 590-596.
-
(2003)
Trends Neurosci
, vol.26
, pp. 590-596
-
-
Goldman, S.1
-
31
-
-
0035320035
-
A unified hypothesis on the lineage of neural stem cells
-
Alvarez-Buylla, A.; García-Verdugo, J.M.; Tramontin, A.D. A unified hypothesis on the lineage of neural stem cells. Nat. Rev. Neurosci. 2001, 2, 287-293.
-
(2001)
Nat. Rev. Neurosci
, vol.2
, pp. 287-293
-
-
Alvarez-Buylla, A.1
García-Verdugo, J.M.2
Tramontin, A.D.3
-
32
-
-
84455193353
-
Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AβPP transgenic mice
-
Rockenstein, E.; Ubhi, K.; Doppler, E.; Novak, P.; Moessler, H.; Li, B.; Blanchard, J.; Grundke-Iqbal, I.; Iqbal, K.; Mante, M. et al. Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AβPP transgenic mice. J. Alzheimer's Dis. 2011, 27, 743-752.
-
(2011)
J. Alzheimer's Dis
, vol.27
, pp. 743-752
-
-
Rockenstein, E.1
Ubhi, K.2
Doppler, E.3
Novak, P.4
Moessler, H.5
Li, B.6
Blanchard, J.7
Grundke-Iqbal, I.8
Iqbal, K.9
Mante, M.10
-
33
-
-
84875030047
-
Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels
-
doi:10.1371/ journal.pone.0058752
-
Lilja, A.M.; Röjdner, J.; Mustafiz, T.; Thomé, C.M.; Storelli, E.; Gonzalez, D.; Unger-Lithner, C.; Greig, N.H.; Nordberg, A.; Marutle, A. Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels. PLoS One 2013, 8, doi:10.1371/ journal.pone.0058752.
-
(2013)
PLoS One
, pp. 8
-
-
Lilja, A.M.1
Röjdner, J.2
Mustafiz, T.3
Thomé, C.M.4
Storelli, E.5
Gonzalez, D.6
Unger-Lithner, C.7
Greig, N.H.8
Nordberg, A.9
Marutle, A.10
-
34
-
-
84880402064
-
Coenzyme Q10 restores amyloid beta-inhibited proliferation of neural stem cells by activating the PI3K pathway
-
Choi, H.; Park, H.H.; Lee, K.Y.; Choi, N.Y.; Yu, H.J.; Lee, Y.J.; Park, J. Huh, Y.M.; Lee, S.H.; Koh, S.H. Coenzyme Q10 restores amyloid beta-inhibited proliferation of neural stem cells by activating the PI3K pathway. Stem Cells Dev. 2013, 22, 2112-2120.
-
(2013)
Stem Cells Dev
, vol.22
, pp. 2112-2120
-
-
Choi, H.1
Park, H.H.2
Lee, K.Y.3
Choi, N.Y.4
Yu, H.J.5
Lee, Y.J.6
Park, J.7
Huh, Y.M.8
Lee, S.H.9
Koh, S.H.10
-
35
-
-
77953506502
-
Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 mice
-
Hu, Y.S.; Xu, P.; Pigino, G.; Brady, S.T.; Larson, J.; Lazarov, O. Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 mice. FASEB J. 2010, 24, 1667-1681.
-
(2010)
FASEB J
, vol.24
, pp. 1667-1681
-
-
Hu, Y.S.1
Xu, P.2
Pigino, G.3
Brady, S.T.4
Larson, J.5
Lazarov, O.6
-
36
-
-
84856715245
-
Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model
-
Kamphuis, W.; Orre, M.; Kooijman, L.; Dahmen, M.; Hol, E.M. Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model. Glia 2012, 60, 615-629.
-
(2012)
Glia
, vol.60
, pp. 615-629
-
-
Kamphuis, W.1
Orre, M.2
Kooijman, L.3
Dahmen, M.4
Hol, E.M.5
-
37
-
-
84881550803
-
Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice
-
Díaz-Moreno, M.; Hortigüela, R.; Gonçalves, A.; García-Carpio, I.; Manich, G.; García-Bermúdez, E.; Moreno-Estellés, M.; Eguiluz, C.; Vilaplana, J.; Pelegrí, C. et al. Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice. Neurobiol. Aging 2013, 34, 2623-2638.
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 2623-2638
-
-
Díaz-Moreno, M.1
Hortigüela, R.2
Gonçalves, A.3
García-Carpio, I.4
Manich, G.5
García-Bermúdez, E.6
Moreno-Estellés, M.7
Eguiluz, C.8
Vilaplana, J.9
Pelegrí, C.10
-
38
-
-
79959962141
-
Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice
-
Kanematsu, S.; Yoshizawa, K.; Uehara, N.; Miki, H.; Sasaki, T.; Kuro, M.; Lai, Y.C.; Kimura, A.; Yuri, T.; Tsubura, A. Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice. Oncol. Rep. 2011, 26, 603-608.
-
(2011)
Oncol. Rep
, vol.26
, pp. 603-608
-
-
Kanematsu, S.1
Yoshizawa, K.2
Uehara, N.3
Miki, H.4
Sasaki, T.5
Kuro, M.6
Lai, Y.C.7
Kimura, A.8
Yuri, T.9
Tsubura, A.10
-
39
-
-
84871805095
-
Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway
-
Li, S.H.; Fu, J.; Watkins, D.N.; Srivastava, R.K.; Shankar, S. Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway. Mol. Cell. Biochem. 2013, 373, 217-227.
-
(2013)
Mol. Cell. Biochem
, vol.373
, pp. 217-227
-
-
Li, S.H.1
Fu, J.2
Watkins, D.N.3
Srivastava, R.K.4
Shankar, S.5
-
40
-
-
84873992343
-
Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation
-
Chen, H.; Landen, C.N.; Li, Y. Alvarez, R.D.; Tollefsbol, T.O. Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation. Exp. Cell Res. 2013, 319, 697-706.
-
(2013)
Exp. Cell Res
, vol.319
, pp. 697-706
-
-
Chen, H.1
Landen, C.N.2
Li, Y.3
Alvarez, R.D.4
Tollefsbol, T.O.5
-
41
-
-
84857919108
-
Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect
-
Zanichelli, F.; Capasso, S.; Cipollaro, M.; Pagnotta, E.; Cartenì, M.; Casale, F.; Iori, R.; Galderisi, U. Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect. Age 2012, 34, 281-293.
-
(2012)
Age
, vol.34
, pp. 281-293
-
-
Zanichelli, F.1
Capasso, S.2
Cipollaro, M.3
Pagnotta, E.4
Cartenì, M.5
Casale, F.6
Iori, R.7
Galderisi, U.8
-
42
-
-
84862689618
-
Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation ofNrf2 in primary rat hepatocytes
-
La Marca, M.; Beffy, P.; Della Croce, C.; Gervasi, P.G.; Iori, R.; Puccinelli, E.; Longo, V. Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation ofNrf2 in primary rat hepatocytes. Food Chem. Toxicol. 2012, 50, 2822-2830.
-
(2012)
Food Chem. Toxicol
, vol.50
, pp. 2822-2830
-
-
la Marca, M.1
Beffy, P.2
della Croce, C.3
Gervasi, P.G.4
Iori, R.5
Puccinelli, E.6
Longo, V.7
-
43
-
-
67649197558
-
Modulation of phase II enzymes by sulforaphane: Implications for its cardioprotective potential
-
Angeloni, C.; Leoncini, E.; Malaguti, M.; Angelini, S.; Hrelia, P.; Hrelia, S. Modulation of phase II enzymes by sulforaphane: Implications for its cardioprotective potential. J. Agric. Food Chem. 2009, 57, 5615-5622.
-
(2009)
J. Agric. Food Chem
, vol.57
, pp. 5615-5622
-
-
Angeloni, C.1
Leoncini, E.2
Malaguti, M.3
Angelini, S.4
Hrelia, P.5
Hrelia, S.6
-
44
-
-
84860488891
-
Dementia from Alzheimer disease and mixed pathologies in the oldest old
-
James, B.D.; Bennett, D.A.; Boyle, P.A.; Leurgans, S.; Schneider, J.A. Dementia from Alzheimer disease and mixed pathologies in the oldest old. JAMA 2012, 307, 1798-1800.
-
(2012)
JAMA
, vol.307
, pp. 1798-1800
-
-
James, B.D.1
Bennett, D.A.2
Boyle, P.A.3
Leurgans, S.4
Schneider, J.A.5
-
45
-
-
84870932482
-
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline
-
Vom Berg, J.; Prokop, S.; Miller, K.R.; Obst, J.; Kälin, R.E.; Lopategui-Cabezas, I.; Wegner, A.; Mair, F.; Schipke, C.G.; Peters, O. et al. Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline. Nat. Med. 2012, 18, 1812-1819.
-
(2012)
Nat. Med
, vol.18
, pp. 1812-1819
-
-
Vom Berg, J.1
Prokop, S.2
Miller, K.R.3
Obst, J.4
Kälin, R.E.5
Lopategui-Cabezas, I.6
Wegner, A.7
Mair, F.8
Schipke, C.G.9
Peters, O.10
-
46
-
-
84905905334
-
Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent notch signaling
-
doi:10.1016/j.stem.2014.05.009
-
Paul, M.K.; Bisht, B.; Darmawan, D.O.; Chiou, R.; Ha, V.L.; Wallace, W.D.; Chon, A.T.; Hegab, A.E.; Grogan, T.; Elashoff, D.A. et al. Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent notch signaling. Cell Stem Cell 2014, doi:10.1016/j.stem.2014.05.009.
-
(2014)
Cell Stem Cell
-
-
Paul, M.K.1
Bisht, B.2
Darmawan, D.O.3
Chiou, R.4
Ha, V.L.5
Wallace, W.D.6
Chon, A.T.7
Hegab, A.E.8
Grogan, T.9
Elashoff, D.A.10
-
47
-
-
84855548457
-
ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression
-
Hoetzenecker, W.; Echtenacher, B.; Guenova, E.; Hoetzenecker, K.; Woelbing, F.; Brück, J.; Teske, A.; Valtcheva, N.; Fuchs, K.; Kneilling, M. et al. ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression. Nat. Med. 2011, 18, 128-134.
-
(2011)
Nat. Med
, vol.18
, pp. 128-134
-
-
Hoetzenecker, W.1
Echtenacher, B.2
Guenova, E.3
Hoetzenecker, K.4
Woelbing, F.5
Brück, J.6
Teske, A.7
Valtcheva, N.8
Fuchs, K.9
Kneilling, M.10
-
48
-
-
0035817443
-
Endomorphins 1 and 2, endogenous mu-opioid receptor agonists, impair passive avoidance learning in mice
-
Ukai, M.; Watanabe, Y.; Kameyama, T. Endomorphins 1 and 2, endogenous mu-opioid receptor agonists, impair passive avoidance learning in mice. Eur. J. Pharmacol. 2001, 421, 115-119.
-
(2001)
Eur. J. Pharmacol
, vol.421
, pp. 115-119
-
-
Ukai, M.1
Watanabe, Y.2
Kameyama, T.3
-
49
-
-
29844442213
-
Effects of systemic administration of beta-casomorphin-5 on learning and memory in mice
-
Sakaguchi, M.; Koseki, M.; Wakamatsu, M.; Matsumura, E. Effects of systemic administration of beta-casomorphin-5 on learning and memory in mice. Eur. J. Pharmacol. 2006, 530, 81-87.
-
(2006)
Eur. J. Pharmacol
, vol.530
, pp. 81-87
-
-
Sakaguchi, M.1
Koseki, M.2
Wakamatsu, M.3
Matsumura, E.4
|