Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway

Molecular and Cellular Biochemistry

Volumn 373, Issue 1-2, 2013, Pages 217-227

  Li, Shih Hui ^a   Fu, Junsheng ^a   Watkins, Dara Nall ^a   Srivastava, Rakesh K ^a   Shankar, Sharmila ^a  

^a UNIVERSITY OF KANSAS CANCER CENTER   (United States)

Author keywords

Cancer stem cells; Epithelial mesenchymal transition; Pancreatic cancer; Pluripotency maintaining factors; Sonic hedgehog pathway; Sulforaphane

Indexed keywords

PROTEIN BCL 2; SONIC HEDGEHOG PROTEIN; SULFORAPHANE; UVOMORULIN; VASCULOTROPIN;

APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER STEM CELL; CARCINOGENESIS; CELL ISOLATION; CONTROLLED STUDY; DISEASE MARKER; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; PANCREAS CANCER; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASTIC STEM CELLS; NEOVASCULARIZATION, PATHOLOGIC; NUCLEAR PROTEINS; OCTAMER TRANSCRIPTION FACTOR-3; PANCREATIC NEOPLASMS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SIGNAL TRANSDUCTION; THIOCYANATES; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ERINACEIDAE; MUS;

EID: 84871805095     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1493-6     Document Type: Article

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