Engineering strategies for the fermentative production of plant alkaloids in yeast

Metabolic Engineering

Volumn 30, Issue , 2015, Pages 96-104

  Trenchard, Isis J ^a   Smolke, Christina D ^a  

^a Stanford University   (United States)

Author keywords

Cytochrome P450; Plant natural products; Synthetic biology; Yeast

Indexed keywords

ALKALOIDS; BIOCHEMISTRY; BIOSYNTHESIS; CHEMICAL COMPOUNDS; ENZYMES; METABOLISM; METABOLITES; NITROGEN COMPOUNDS; PLANTS (BOTANY); PRODUCTION PLATFORMS;

BENZYLISOQUINOLINE ALKALOIDS; CULTURE OPTIMIZATIONS; CYTOCHROME P450; CYTOCHROME P450 ENZYMES; FERMENTATIVE PRODUCTION; MICROBIAL BIOSYNTHESIS; NATURAL PRODUCTS; SYNTHETIC BIOLOGY;

YEAST;

BENZOPHENANTHRIDINE DERIVATIVE; CHEILANTHIFOLINE; CIS N METHYLSTYLOPINE; CYTOCHROME P450; PROTOBERBERINE; PROTOPINE; SANGUINARINE; STYLOPINE; UNCLASSIFIED DRUG; ALKALOID; PLANT PROTEIN;

ARTICLE; BIOENGINEERING; CARBON SOURCE; CELLULAR DISTRIBUTION; CULTURE OPTIMIZATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME LOCALIZATION; FERMENTATION; FUNGAL STRAIN; HETEROLOGOUS EXPRESSION; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; SUBSTRATE CONCENTRATION; BIOSYNTHESIS; GENETICS; METABOLIC ENGINEERING; METABOLISM; PROCEDURES;

SACCHAROMYCES CEREVISIAE;

ALKALOIDS; CYTOCHROME P-450 ENZYME SYSTEM; METABOLIC ENGINEERING; PLANT PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 84930615040     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.05.001     Document Type: Article

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