Molecular modeling and spectroscopic studies of semustine binding with DNA and its comparison with lomustine-DNA adduct formation

Journal of Biomolecular Structure and Dynamics

Volumn 33, Issue 8, 2015, Pages 1653-1668

  Agarwal, Shweta ^a   Chadha, Deepti ^a   Mehrotra, Ranjana ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

CD spectroscopy; Drug DNA interaction; FTIR spectroscopy; lomustine; molecular modeling; semustine

Indexed keywords

LOMUSTINE; SEMUSTINE; ALKYLATING AGENT; DNA; DNA ADDUCT;

ABSORPTION SPECTROSCOPY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA ALKYLATION; DRUG BINDING SITE; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG DNA INTERACTION; DRUG STABILITY; DRUG STRUCTURE; INCUBATION TIME; INFRARED SPECTROSCOPY; MOLECULAR DOCKING; MOLECULAR MODEL; PRIORITY JOURNAL; ALGORITHM; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DNA ADDUCT; METABOLISM; MOLECULAR DYNAMICS;

ALGORITHMS; ANTINEOPLASTIC AGENTS, ALKYLATING; CIRCULAR DICHROISM; DNA; DNA ADDUCTS; LOMUSTINE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; SEMUSTINE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84930571766     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2014.968874     Document Type: Article

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