SOX7 interferes with β-catenin activity to promote neuronal apoptosis

European Journal of Neuroscience

Volumn 41, Issue 11, 2015, Pages 1430-1437

  Wang, Chong ^a   Qin, Lina ^b   Min, Zhiqun ^c   Zhao, Yiwei ^a   Zhu, Lin ^a   Zhu, Jing ^a   Yu, Shaojun ^a  

^a XIAMEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Neuronal apoptosis; Rat; SOX7; catenin

Indexed keywords

BETA CATENIN; MESSENGER RNA; POTASSIUM; TRANSCRIPTION FACTOR SOX7; TRANSCRIPTION FACTOR SOX;

ANIMAL CELL; APOPTOSIS; ARTICLE; CEREBELLUM GRANULAR LAYER; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL CULTURE; CEREBELLUM; METABOLISM; NERVE CELL; POTASSIUM DEFICIENCY; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BETA CATENIN; CELLS, CULTURED; CEREBELLUM; NEURONS; POTASSIUM DEFICIENCY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SOXF TRANSCRIPTION FACTORS;

EID: 84930484431     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/ejn.12910     Document Type: Article

References (41)

1. Akiyama, H., Lyons, J.P., Mori-Akiyama, Y., Yang, X., Zhang, R., Zhang, Z., Deng, J.M., Taketo, M.M., Nakamura, T., Behringer, R.R., McCrea, P.D. & de Crombrugghe, B. (2004) Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Gene. Dev., 18, 1072-1087.
2. Brewster, J.L., Linseman, D.A., Bouchard, R.J., Loucks, F.A., Precht, T.A., Esch, E.A. & Heidenreich, K.A. (2006) Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons. Mol. Cell. Neurosci., 32, 242-253.
3. Clevers, H. & Nusse, R. (2012) Wnt/beta-catenin signaling and disease. Cell, 149, 1192-1205.
4. D'Mello, S.R., Galli, C., Ciotti, T. & Calissano, P. (1993) Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. Proc. Natl. Acad. Sci. USA, 90, 10989-10993.
5. Elmore, S. (2007) Apoptosis: a review of programmed cell death. Toxicol. Pathol., 35, 495-516.
6. Ferri, A.L., Cavallaro, M., Braida, D., Di Cristofano, A., Canta, A., Vezzani, A., Ottolenghi, S., Pandolfi, P.P., Sala, M., DeBiasi, S. & Nicolis, S.K. (2004) Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development, 131, 3805-3819.
7. Flentke, G.R., Garic, A., Hernandez, M. & Smith, S.M. (2014) CaMKII represses transcriptionally active beta-catenin to mediate acute ethanol neurodegeneration and can phosphorylate beta-catenin. J. Neurochem., 128, 523-535.
8. Gould, T.D., Einat, H., O'Donnell, K.C., Picchini, A.M., Schloesser, R.J. & Manji, H.K. (2007) Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors. Neuropsychopharmacology, 32, 2173-2183.
9. Gray, J.J., Zommer, A.E., Bouchard, R.J., Duval, N., Blackstone, C. & Linseman, D.A. (2013) N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress. Brain Res., 1494, 28-43.
10. Guger, K.A. & Gumbiner, B.M. (2000) A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels. Dev. Biol., 223, 441-448.
11. Guo, L., Zhong, D., Lau, S., Liu, X., Dong, X.Y., Sun, X., Yang, V.W., Vertino, P.M., Moreno, C.S., Varma, V., Dong, J.T. & Zhou, W. (2008) Sox7 is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Mol. Cancer Res., 6, 1421-1430.
12. Hino, S., Tanji, C., Nakayama, K.I. & Kikuchi, A. (2005) Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination. Mol. Cell. Biol., 25, 9063-9072.
13. Iguchi, H., Urashima, Y., Inagaki, Y., Ikeda, Y., Okamura, M., Tanaka, T., Uchida, A., Yamamoto, T.T., Kodama, T. & Sakai, J. (2007) SOX6 suppresses cyclin D1 promoter activity by interacting with beta-catenin and histone deacetylase 1, and its down-regulation induces pancreatic beta-cell proliferation. J. Biol. Chem., 282, 19052-19061.
14. Jankowski, M.P., Cornuet, P.K., McIlwrath, S., Koerber, H.R. & Albers, K.M. (2006) SRY-box containing gene 11 (Sox11) transcription factor is required for neuron survival and neurite growth. Neuroscience, 143, 501-514.
15. Kim, K., Pang, K.M., Evans, M. & Hay, E.D. (2000) Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators. Mol. Biol. Cell, 11, 3509-3523.
16. L'Episcopo, F., Serapide, M.F., Tirolo, C., Testa, N., Caniglia, S., Morale, M.C., Pluchino, S. & Marchetti, B. (2011) A Wnt1 regulated Frizzled-1/beta-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: therapeutical relevance for neuron survival and neuroprotection. Mol. Neurodegener., 6, 49.
17. Li, W., Tong, H., Huang, X., Wang, W., Wu, H. & Lin, S. (2012) High levels of beta-catenin promote IFNgamma-induced apoptosis in hepatocellular carcinoma cells. Oncol. Lett., 4, 1092-1096.
18. Lu, W., Jia, G., Meng, X., Zhao, C., Zhang, L., Ren, Y., Pan, H. & Ni, Y. (2012) Beta-catenin mediates the apoptosis induction effect of celastrol in HT29 cells. Life Sci., 91, 279-283.
19. MacDonald, B.T., Tamai, K. & He, X. (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell, 17, 9-26.
20. Monga, S.P., Mars, W.M., Pediaditakis, P., Bell, A., Mule, K., Bowen, W.C., Wang, X., Zarnegar, R. & Michalopoulos, G.K. (2002) Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes. Cancer Res., 62, 2064-2071.
21. Pevny, L.H. & Nicolis, S.K. (2010) Sox2 roles in neural stem cells. Int. J. Biochem. Cell B., 42, 421-424.
22. Quintanilla, R.A., Munoz, F.J., Metcalfe, M.J., Hitschfeld, M., Olivares, G., Godoy, J.A. & Inestrosa, N.C. (2005) Trolox and 17beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway. J. Biol. Chem., 280, 11615-11625.
23. de la Rocha, A.M., Sampron, N., Alonso, M.M. & Matheu, A. (2014) Role of SOX family of transcription factors in central nervous system tumors. Am. J. Cancer Res., 4, 312-324.
24. Sastry, P.S. & Rao, K.S. (2000) Apoptosis and the nervous system. J. Neurochem., 74, 1-20.
25. Scott, C.E., Wynn, S.L., Sesay, A., Cruz, C., Cheung, M., Gomez Gaviro, M.V., Booth, S., Gao, B., Cheah, K.S., Lovell-Badge, R. & Briscoe, J. (2010) SOX9 induces and maintains neural stem cells. Nat. Neurosci., 13, 1181-1189.
26. Shibamoto, S., Hayakawa, M., Takeuchi, K., Hori, T., Oku, N., Miyazawa, K., Kitamura, N., Takeichi, M. & Ito, F. (1994) Tyrosine phosphorylation of beta-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhes. Commun., 1, 295-305.
27. Sinner, D., Kordich, J.J., Spence, J.R., Opoka, R., Rankin, S., Lin, S.C., Jonatan, D., Zorn, A.M. & Wells, J.M. (2007) Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol. Cell. Biol., 27, 7802-7815.
28. Song, B., Xie, B., Wang, C. & Li, M. (2011) Caspase-3 is a target gene of c-Jun:ATF2 heterodimers during apoptosis induced by activity deprivation in cerebellar granule neurons. Neurosci. Lett., 505, 76-81.
29. Stovall, D.B., Cao, P. & Sui, G. (2014) SOX7: from a developmental regulator to an emerging tumor suppressor. Histol. Histopathol., 29, 439-445.
30. Takash, W., Canizares, J., Bonneaud, N., Poulat, F., Mattei, M.G., Jay, P. & Berta, P. (2001) SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signalling. Nucleic Acids Res., 29, 4274-4283.
31. Taurin, S., Sandbo, N., Qin, Y., Browning, D. & Dulin, N.O. (2006) Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase. J. Biol. Chem., 281, 9971-9976.
32. Valenta, T., Hausmann, G. & Basler, K. (2012) The many faces and functions of beta-catenin. EMBO J., 31, 2714-2736.
33. Wang, C., Guo, Y., Wang, J. & Min, Z. (2014) The suppressive role of SOX7 in hepatocarcinogenesis. PLoS One, 9, e97433.
34. Wegner, M. (1999) From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res., 27, 1409-1420.
35. Wei, L., Sun, C., Lei, M., Li, G., Yi, L., Luo, F., Li, Y., Ding, L., Liu, Z., Li, S. & Xu, P. (2013) Activation of Wnt/beta-catenin pathway by exogenous Wnt1 protects SH-SY5Y cells against 6-hydroxydopamine toxicity. J. Mol. Neurosci., 49, 105-115.
36. Wisniewska, M.B. (2013) Physiological role of beta-catenin/TCF signaling in neurons of the adult brain. Neurochem. Res., 38, 1144-1155.
37. Xie, B., Wang, C., Zheng, Z., Song, B., Ma, C., Thiel, G. & Li, M. (2011) Egr-1 transactivates Bim gene expression to promote neuronal apoptosis. J. Neurosci., 31, 5032-5044.
38. Yuan, J. & Yankner, B.A. (2000) Apoptosis in the nervous system. Nature, 407, 802-809.
39. Zhang, Z., Hartmann, H., Do, V.M., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., van de Wetering, M., Clevers, H., Saftig, P., De Strooper, B., He, X. & Yankner, B.A. (1998) Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature, 395, 698-702.
40. Zhang, Y., Huang, S., Dong, W., Li, L., Feng, Y., Pan, L., Han, Z., Wang, X., Ren, G., Su, D., Huang, B. & Lu, J. (2009) SOX7, down-regulated in colorectal cancer, induces apoptosis and inhibits proliferation of colorectal cancer cells. Cancer Lett., 277, 29-37.
41. Zorn, A.M., Barish, G.D., Williams, B.O., Lavender, P., Klymkowsky, M.W. & Varmus, H.E. (1999) Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin. Mol. Cell, 4, 487-498.