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Volumn 181, Issue 1, 2015, Pages 1-18

The T cell antigen receptor: The Swiss army knife of the immune system

Author keywords

CD1; MHC I; MHC Ib; MHC II; MR1; T cell; T cell receptor; TCR; TCR

Indexed keywords

LIPID; LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR; BUTYROPHILIN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; MEMBRANE PROTEIN;

EID: 84930416677     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12622     Document Type: Article
Times cited : (46)

References (122)
  • 1
    • 0016345568 scopus 로고
    • Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system
    • Zinkernagel RM, Doherty PC. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 1974; 248:701-2.
    • (1974) Nature , vol.248 , pp. 701-702
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 2
    • 0037434974 scopus 로고    scopus 로고
    • Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1
    • Treiner E, Duban L, Bahram S et al. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 2003; 422:164-9.
    • (2003) Nature , vol.422 , pp. 164-169
    • Treiner, E.1    Duban, L.2    Bahram, S.3
  • 3
    • 77954914800 scopus 로고    scopus 로고
    • Antimicrobial activity of mucosal-associated invariant T cells
    • Le Bourhis L, Martin E, Peguillet I et al. Antimicrobial activity of mucosal-associated invariant T cells. Nat Immunol 2010; 11:701-8.
    • (2010) Nat Immunol , vol.11 , pp. 701-708
    • Le Bourhis, L.1    Martin, E.2    Peguillet, I.3
  • 5
    • 84879377957 scopus 로고    scopus 로고
    • A conserved human T cell population targets mycobacterial antigens presented by CD1b
    • Van Rhijn I, Kasmar A, de Jong A et al. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat Immunol 2014; 14:706-13.
    • (2014) Nat Immunol , vol.14 , pp. 706-713
    • Van Rhijn, I.1    Kasmar, A.2    de Jong, A.3
  • 6
    • 0036582288 scopus 로고    scopus 로고
    • γδ T cells: functional plasticity and heterogeneity
    • Carding SR, Egan PJ. γδ T cells: functional plasticity and heterogeneity. Nat Rev Immunol 2002; 2:336-45.
    • (2002) Nat Rev Immunol , vol.2 , pp. 336-345
    • Carding, S.R.1    Egan, P.J.2
  • 7
    • 84930416297 scopus 로고    scopus 로고
    • The molecular bases of δ/αβ T cell-mediated antigen recognition
    • Pellicci DG, Uldrich AP, Le Nours J et al. The molecular bases of δ/αβ T cell-mediated antigen recognition. J Exp Med 2014; 211:2599-615.
    • (2014) J Exp Med , vol.211 , pp. 2599-2615
    • Pellicci, D.G.1    Uldrich, A.P.2    Le Nours, J.3
  • 8
    • 33646486087 scopus 로고    scopus 로고
    • TCR trans-rearrangements: biological significance in antigen recognition vs the role as lymphoma biomarker
    • Allam A, Kabelitz D. TCR trans-rearrangements: biological significance in antigen recognition vs the role as lymphoma biomarker. J Immunol 2006; 176:5707-12.
    • (2006) J Immunol , vol.176 , pp. 5707-5712
    • Allam, A.1    Kabelitz, D.2
  • 9
    • 84891066514 scopus 로고    scopus 로고
    • A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restriction
    • Bowen S, Sun P, Livak F, Sharrow S, Hodes RJ. A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restriction. J Immunol 2014; 192:169-77.
    • (2014) J Immunol , vol.192 , pp. 169-177
    • Bowen, S.1    Sun, P.2    Livak, F.3    Sharrow, S.4    Hodes, R.J.5
  • 10
    • 70350438026 scopus 로고    scopus 로고
    • Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor
    • Cole DK, Yuan F, Rizkallah PJ et al. Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. J Biol Chem 2009; 284:27281-9.
    • (2009) J Biol Chem , vol.284 , pp. 27281-27289
    • Cole, D.K.1    Yuan, F.2    Rizkallah, P.J.3
  • 12
    • 77954411152 scopus 로고    scopus 로고
    • Allelic polymorphism in the T cell receptor and its impact on immune responses
    • Gras S, Chen Z, Miles JJ et al. Allelic polymorphism in the T cell receptor and its impact on immune responses. J Exp Med 2010; 207:1555-67.
    • (2010) J Exp Med , vol.207 , pp. 1555-1567
    • Gras, S.1    Chen, Z.2    Miles, J.J.3
  • 13
    • 84866419166 scopus 로고    scopus 로고
    • Why must T cells be cross-reactive?
    • Sewell AK. Why must T cells be cross-reactive? Nat Rev Immunol 2012; 2:669-77.
    • (2012) Nat Rev Immunol , vol.2 , pp. 669-677
    • Sewell, A.K.1
  • 14
    • 0023720148 scopus 로고
    • T cell antigen receptor genes and T cell recognition
    • Davis MM, Bjorkmann PJ. T cell antigen receptor genes and T cell recognition. Nature 1988; 334:395-402.
    • (1988) Nature , vol.334 , pp. 395-402
    • Davis, M.M.1    Bjorkmann, P.J.2
  • 15
    • 0024502409 scopus 로고
    • The thymus selects the useful, neglects the useless and destroys the harmful
    • Van Boehmer H, Teh HS, Kisielow P. The thymus selects the useful, neglects the useless and destroys the harmful. Immunol Today 1989; 10:57-61.
    • (1989) Immunol Today , vol.10 , pp. 57-61
    • Van Boehmer, H.1    Teh, H.S.2    Kisielow, P.3
  • 16
    • 0028863822 scopus 로고    scopus 로고
    • Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes
    • Bendelac A. Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J Exp Med 182:2091-6.
    • J Exp Med , vol.182 , pp. 2091-2096
    • Bendelac, A.1
  • 17
    • 0034162512 scopus 로고    scopus 로고
    • NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells
    • Coles MC, Raulet DH. NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells. J Immunol 2000; 164:2412-8.
    • (2000) J Immunol , vol.164 , pp. 2412-2418
    • Coles, M.C.1    Raulet, D.H.2
  • 18
    • 22944442645 scopus 로고    scopus 로고
    • Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes
    • Wei DG, Lee H, Park HS et al. Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med 2005; 202:239-48.
    • (2005) J Exp Med , vol.202 , pp. 239-248
    • Wei, D.G.1    Lee, H.2    Park, H.S.3
  • 19
    • 84890395899 scopus 로고    scopus 로고
    • Double-positive thymocytes select mucosal-associated invariant T cells
    • Seach N, Guerri L, Le Bourhis L et al. Double-positive thymocytes select mucosal-associated invariant T cells. J Immunol 2013; 191:6002-9.
    • (2013) J Immunol , vol.191 , pp. 6002-6009
    • Seach, N.1    Guerri, L.2    Le Bourhis, L.3
  • 20
    • 0030019723 scopus 로고    scopus 로고
    • T cell receptor δ gene rearrangement and T early α (TEA) expression in immature αβ lineage thymocytes: implications for αβ/γδ lineage commitment
    • Wilson A, de Villartay JP, MacDonal HR. T cell receptor δ gene rearrangement and T early α (TEA) expression in immature αβ lineage thymocytes: implications for αβ/γδ lineage commitment. Immunity 1996; 4:37-45.
    • (1996) Immunity , vol.4 , pp. 37-45
    • Wilson, A.1    de Villartay, J.P.2    MacDonal, H.R.3
  • 21
    • 84893754754 scopus 로고    scopus 로고
    • The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification
    • Coffey F, Lee SY, Buus TB et al. The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification. J Exp Med 2014; 211:329-43.
    • (2014) J Exp Med , vol.211 , pp. 329-343
    • Coffey, F.1    Lee, S.Y.2    Buus, T.B.3
  • 22
    • 79960447248 scopus 로고    scopus 로고
    • Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells
    • Turchinovich G, Hayday AC. Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells. Immunity 2011; 35:59-68.
    • (2011) Immunity , vol.35 , pp. 59-68
    • Turchinovich, G.1    Hayday, A.C.2
  • 23
    • 46749113368 scopus 로고    scopus 로고
    • Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma
    • Jensen KD, Su X, Shin S et al. Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity 2008; 29:90-100.
    • (2008) Immunity , vol.29 , pp. 90-100
    • Jensen, K.D.1    Su, X.2    Shin, S.3
  • 25
    • 21244484755 scopus 로고    scopus 로고
    • High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance
    • Tynan FE, Borg NA, Miles JJ et al. High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance. J Biol Chem 2005; 280:23900-9.
    • (2005) J Biol Chem , vol.280 , pp. 23900-23909
    • Tynan, F.E.1    Borg, N.A.2    Miles, J.J.3
  • 26
    • 0036183981 scopus 로고    scopus 로고
    • Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1
    • Mullen MM, Haan KM, Longnecker R, Jardetzky TS. Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1. Mol Cell 2002; 9:375-85.
    • (2002) Mol Cell , vol.9 , pp. 375-385
    • Mullen, M.M.1    Haan, K.M.2    Longnecker, R.3    Jardetzky, T.S.4
  • 27
    • 84874098478 scopus 로고    scopus 로고
    • Peptide length determines the outcome of TCR/peptide-MHCI engagement
    • Ekeruche-Makinde J, Miles JJ, van den Berg HA et al. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 2013; 121:1112-23.
    • (2013) Blood , vol.121 , pp. 1112-1123
    • Ekeruche-Makinde, J.1    Miles, J.J.2    van den Berg, H.A.3
  • 28
    • 6344272484 scopus 로고    scopus 로고
    • Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501
    • Probst-Kepper M, Hecht HJ, Herrmann H et al. Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501. J Immunol 2004; 173:5610-6.
    • (2004) J Immunol , vol.173 , pp. 5610-5616
    • Probst-Kepper, M.1    Hecht, H.J.2    Herrmann, H.3
  • 29
    • 33750832289 scopus 로고    scopus 로고
    • TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope
    • Miles JJ, Borg NA, Brennan RM et al. TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope. J Immunol 2006; 177:6804-14.
    • (2006) J Immunol , vol.177 , pp. 6804-6814
    • Miles, J.J.1    Borg, N.A.2    Brennan, R.M.3
  • 30
    • 43249126282 scopus 로고    scopus 로고
    • Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
    • Wynn KK, Fulton Z, Cooper L et al. Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection. Blood 2008; 111:4283-92.
    • (2008) Blood , vol.111 , pp. 4283-4292
    • Wynn, K.K.1    Fulton, Z.2    Cooper, L.3
  • 31
    • 0029965954 scopus 로고    scopus 로고
    • An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501
    • Smith KJ, Reid SW, Stuart DI, McMichael AJ, Jones EY, Bell JI. An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501. Immunity 1996; 4:203-13.
    • (1996) Immunity , vol.4 , pp. 203-213
    • Smith, K.J.1    Reid, S.W.2    Stuart, D.I.3    McMichael, A.J.4    Jones, E.Y.5    Bell, J.I.6
  • 32
    • 0035884987 scopus 로고    scopus 로고
    • Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes
    • Sliz P, Michielin O, Cerottini JC et al. Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes. J Immunol 2001; 167:3276-84.
    • (2001) J Immunol , vol.167 , pp. 3276-3284
    • Sliz, P.1    Michielin, O.2    Cerottini, J.C.3
  • 33
    • 0027525106 scopus 로고
    • The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2
    • Madden DR, Garboczi DN, Wiley DC. The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. Cell 1993; 75:693-708.
    • (1993) Cell , vol.75 , pp. 693-708
    • Madden, D.R.1    Garboczi, D.N.2    Wiley, D.C.3
  • 34
    • 10744220502 scopus 로고    scopus 로고
    • Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy
    • Siebold C, Hansen BE, Wyer JR et al. Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. Proc Natl Acad Sci USA 2004; 101:1999-2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1999-2004
    • Siebold, C.1    Hansen, B.E.2    Wyer, J.R.3
  • 35
    • 0030701632 scopus 로고    scopus 로고
    • X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II
    • Dessen A, Lawrence CM, Cupo S, Zaller DM, Wiley DC. X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II. Immunity 1997; 7:473-81.
    • (1997) Immunity , vol.7 , pp. 473-481
    • Dessen, A.1    Lawrence, C.M.2    Cupo, S.3    Zaller, D.M.4    Wiley, D.C.5
  • 36
    • 34248530182 scopus 로고    scopus 로고
    • Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
    • Deng L, Langley RJ, Brown PH et al. Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor. Nat Immunol 2007; 8:398-408.
    • (2007) Nat Immunol , vol.8 , pp. 398-408
    • Deng, L.1    Langley, R.J.2    Brown, P.H.3
  • 38
    • 0025147562 scopus 로고
    • Positive Darwinian selection promotes charge profile diversity in the antigen-binding cleft of class I major-histocompatibility-complex molecules
    • Hughes AL, Ota T, Nei M. Positive Darwinian selection promotes charge profile diversity in the antigen-binding cleft of class I major-histocompatibility-complex molecules. Mol Biol Evol 1990; 7:515-24.
    • (1990) Mol Biol Evol , vol.7 , pp. 515-524
    • Hughes, A.L.1    Ota, T.2    Nei, M.3
  • 40
    • 79251518600 scopus 로고    scopus 로고
    • Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection
    • Miles JJ, Bulek AM, Cole DK et al. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLOS Pathog 2010; 6:e1001198.
    • (2010) PLOS Pathog , vol.6 , pp. e1001198
    • Miles, J.J.1    Bulek, A.M.2    Cole, D.K.3
  • 41
    • 79952750632 scopus 로고    scopus 로고
    • Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection
    • Yin Y, Li Y, Kerzic MC, Martin R, Mariuzza RA. Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection. EMBO J 2011; 30:1137-48.
    • (2011) EMBO J , vol.30 , pp. 1137-1148
    • Yin, Y.1    Li, Y.2    Kerzic, M.C.3    Martin, R.4    Mariuzza, R.A.5
  • 44
    • 58649114309 scopus 로고    scopus 로고
    • The molecular basis of TCR germline bias for MHC is surprisingly simple
    • Garcia KC, Adams JJ, Feng D, Ely LK. The molecular basis of TCR germline bias for MHC is surprisingly simple. Nat Immunol 2009; 10:143.
    • (2009) Nat Immunol , vol.10 , pp. 143
    • Garcia, K.C.1    Adams, J.J.2    Feng, D.3    Ely, L.K.4
  • 45
    • 84865281416 scopus 로고    scopus 로고
    • Reconciling views on T cell receptor germline bias for MHC
    • Garcia KC. Reconciling views on T cell receptor germline bias for MHC. Trends Immunol 2012; 33:429-36.
    • (2012) Trends Immunol , vol.33 , pp. 429-436
    • Garcia, K.C.1
  • 46
    • 34548128306 scopus 로고    scopus 로고
    • Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
    • Feng D, Bond CJ, Ely LK, Maynard J, Garcia KC. Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'. Nat Immunol 2007; 8:975-83.
    • (2007) Nat Immunol , vol.8 , pp. 975-983
    • Feng, D.1    Bond, C.J.2    Ely, L.K.3    Maynard, J.4    Garcia, K.C.5
  • 47
    • 81955161800 scopus 로고    scopus 로고
    • A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands
    • Stadinski BD, Trenh P, Smith RL et al. A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands. Immunity 2011; 35:694-704.
    • (2011) Immunity , vol.35 , pp. 694-704
    • Stadinski, B.D.1    Trenh, P.2    Smith, R.L.3
  • 48
    • 77953742968 scopus 로고    scopus 로고
    • Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
    • Burrows SR, Chen Z, Archbold JK et al. Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability. Proc Natl Acad Sci USA 2010; 107:10608-13.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10608-10613
    • Burrows, S.R.1    Chen, Z.2    Archbold, J.K.3
  • 49
    • 84868556955 scopus 로고    scopus 로고
    • The T-cell receptor is not hardwired to engage MHC ligands
    • Holland SJ, Bartok I, Attaf M et al. The T-cell receptor is not hardwired to engage MHC ligands. Proc Natl Acad Sci USA 2012; 109:E3111-8.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. E3111-E3118
    • Holland, S.J.1    Bartok, I.2    Attaf, M.3
  • 50
    • 84859470532 scopus 로고    scopus 로고
    • Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC
    • Yin Y, Wang XX, Mariuzza RA. Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC. Proc Natl Acad Sci USA 2012; 109:5405-10.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 5405-5410
    • Yin, Y.1    Wang, X.X.2    Mariuzza, R.A.3
  • 51
    • 84891939529 scopus 로고    scopus 로고
    • T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions
    • Cole DK, Miles KM, Madura Fet al. T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions. J Biol Chem 2013; 289:628-38.
    • (2013) J Biol Chem , vol.289 , pp. 628-638
    • Cole, D.K.1    Miles, K.M.2    Madura, F.3
  • 52
    • 0030926140 scopus 로고    scopus 로고
    • Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2
    • Gao GF, Tormo J, Gerth UC et al. Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2. Nature 1997; 387:630-4.
    • (1997) Nature , vol.387 , pp. 630-634
    • Gao, G.F.1    Tormo, J.2    Gerth, U.C.3
  • 53
    • 36048942337 scopus 로고    scopus 로고
    • Deletion of CD4 and CD8 coreceptors permits generation of αβT cells that recognize antigens independently of the MHC
    • Van Laethem F, Sarafova SD, Park JH et al. Deletion of CD4 and CD8 coreceptors permits generation of αβT cells that recognize antigens independently of the MHC. Immunity 2007; 27:735-50.
    • (2007) Immunity , vol.27 , pp. 735-750
    • Van Laethem, F.1    Sarafova, S.D.2    Park, J.H.3
  • 54
    • 84856291875 scopus 로고    scopus 로고
    • αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities
    • Tikhonova AN, Van Laethem F, Hanada K et al. αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities. Immunity 2012; 36:79-91.
    • (2012) Immunity , vol.36 , pp. 79-91
    • Tikhonova, A.N.1    Van Laethem, F.2    Hanada, K.3
  • 55
    • 84865282273 scopus 로고    scopus 로고
    • MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection
    • Van Laethem F, Tikhonova AN, Singer A. MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection. Trends Immunol 2012; 33:437-41.
    • (2012) Trends Immunol , vol.33 , pp. 437-441
    • Van Laethem, F.1    Tikhonova, A.N.2    Singer, A.3
  • 56
    • 84884248064 scopus 로고    scopus 로고
    • Lck availability during thymic selection determines the recognition specificity of the T cell repertoire
    • Van Laethem F, Tikhonova AN, Pobezinsky LA et al. Lck availability during thymic selection determines the recognition specificity of the T cell repertoire. Cell 2013; 154:1326-41.
    • (2013) Cell , vol.154 , pp. 1326-1341
    • Van Laethem, F.1    Tikhonova, A.N.2    Pobezinsky, L.A.3
  • 57
    • 0021214164 scopus 로고
    • Binding of antigen in the absence of histocompatibility proteins by arsonate-reactive T-cell clones
    • Rao A, Ko WW, Faas SJ, Cantor H. Binding of antigen in the absence of histocompatibility proteins by arsonate-reactive T-cell clones. Cell 1984; 36:879-88.
    • (1984) Cell , vol.36 , pp. 879-888
    • Rao, A.1    Ko, W.W.2    Faas, S.J.3    Cantor, H.4
  • 58
    • 0024454148 scopus 로고
    • Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells
    • Barnd DL, Lan MS, Metzgar RS, Finn OJ. Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells. Proc Natl Acad Sci USA 1989; 86:7159-63.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7159-7163
    • Barnd, D.L.1    Lan, M.S.2    Metzgar, R.S.3    Finn, O.J.4
  • 59
    • 79955969751 scopus 로고    scopus 로고
    • Molecular identification of an MHC-independent ligand recognized by a human α/β T-cell receptor
    • Hanada K, Wang QJ, Inozume T, Yang JC. Molecular identification of an MHC-independent ligand recognized by a human α/β T-cell receptor. Blood 2011; 117:4816-25.
    • (2011) Blood , vol.117 , pp. 4816-4825
    • Hanada, K.1    Wang, Q.J.2    Inozume, T.3    Yang, J.C.4
  • 60
    • 0032171644 scopus 로고    scopus 로고
    • A very high level of crossreactivity is an essential feature of the T-cell receptor
    • Mason D. A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today 1998; 19:395-404.
    • (1998) Immunol Today , vol.19 , pp. 395-404
    • Mason, D.1
  • 61
    • 84855497162 scopus 로고    scopus 로고
    • A single autoimmune T cell receptor recognizes more than a million different peptides
    • Wooldridge L, Ekeruche-Makinde J, van den Berg HA et al. A single autoimmune T cell receptor recognizes more than a million different peptides. J Biol Chem 2012; 287:1168-77.
    • (2012) J Biol Chem , vol.287 , pp. 1168-1177
    • Wooldridge, L.1    Ekeruche-Makinde, J.2    van den Berg, H.A.3
  • 62
    • 84857189975 scopus 로고    scopus 로고
    • Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes
    • Bulek AM, Cole DK, Skowera A et al. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nat Immunol 2012; 13:283-9.
    • (2012) Nat Immunol , vol.13 , pp. 283-289
    • Bulek, A.M.1    Cole, D.K.2    Skowera, A.3
  • 63
    • 84901295133 scopus 로고    scopus 로고
    • Deconstructing the peptide-MHC specificity of T cell recognition
    • Birnbaum ME, Mendoza JL, Sethi DK et al. Deconstructing the peptide-MHC specificity of T cell recognition. Cell 2014; 157:1073-87.
    • (2014) Cell , vol.157 , pp. 1073-1087
    • Birnbaum, M.E.1    Mendoza, J.L.2    Sethi, D.K.3
  • 64
    • 84923104148 scopus 로고    scopus 로고
    • Structural basis for ineffective T-cell responses to MHC anchor residue-improved 'heteroclitic' peptides
    • Madura F, Rizkallah PJ, Holland CJ et al. Structural basis for ineffective T-cell responses to MHC anchor residue-improved 'heteroclitic' peptides. Eur J Immunol 2015; 45:584-91.
    • (2015) Eur J Immunol , vol.45 , pp. 584-591
    • Madura, F.1    Rizkallah, P.J.2    Holland, C.J.3
  • 65
    • 77956914881 scopus 로고    scopus 로고
    • Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition
    • Cole DK, Edwards ES, Wynn KK et al. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. J Immunol 2010; 185:2600-10.
    • (2010) J Immunol , vol.185 , pp. 2600-2610
    • Cole, D.K.1    Edwards, E.S.2    Wynn, K.K.3
  • 69
    • 0036593039 scopus 로고    scopus 로고
    • No one is naive: the significance of heterologous T-cell immunity
    • Welsh RM, Selin LK. No one is naive: the significance of heterologous T-cell immunity. Nat Rev Immunol 2002; 2:417-26.
    • (2002) Nat Rev Immunol , vol.2 , pp. 417-426
    • Welsh, R.M.1    Selin, L.K.2
  • 70
    • 84874253445 scopus 로고    scopus 로고
    • Virus-specific CD4+ memory-phenotype T cells are abundant in unexposed adults
    • Su LF, Kidd BA, Han A, Kotzin JJ, Davis MM. Virus-specific CD4+ memory-phenotype T cells are abundant in unexposed adults. Immunity 2013; 38:373-83.
    • (2013) Immunity , vol.38 , pp. 373-383
    • Su, L.F.1    Kidd, B.A.2    Han, A.3    Kotzin, J.J.4    Davis, M.M.5
  • 71
    • 79953162407 scopus 로고    scopus 로고
    • T cell receptor recognition of self and foreign antigens in the induction of autoimmunity
    • Wucherpfennig KW, Sethi D. T cell receptor recognition of self and foreign antigens in the induction of autoimmunity. Semin Immunol 2011; 23:84-91.
    • (2011) Semin Immunol , vol.23 , pp. 84-91
    • Wucherpfennig, K.W.1    Sethi, D.2
  • 73
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: harnessing the T cell response
    • Restifo NP, Dudley ME, Rosenberg SA. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol 2012; 12:269-81.
    • (2012) Nat Rev Immunol , vol.12 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 74
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan RA, Dudley ME, Wunderlich JR et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006; 314:126-9.
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3
  • 75
    • 21444445173 scopus 로고    scopus 로고
    • Directed evolution of human T-cell receptors with picomolar affinities by phage display
    • Li Y, Moysey R, Molloy PE et al. Directed evolution of human T-cell receptors with picomolar affinities by phage display. Nat Biotechnol 2005; 23:349-54.
    • (2005) Nat Biotechnol , vol.23 , pp. 349-354
    • Li, Y.1    Moysey, R.2    Molloy, P.E.3
  • 77
    • 84862589122 scopus 로고    scopus 로고
    • Cutting edge: evidence for a dynamically driven T cell signaling mechanism
    • Hawse WF, Champion MM, Joyce MV et al. Cutting edge: evidence for a dynamically driven T cell signaling mechanism. J Immunol 2012; 188:5819-23.
    • (2012) J Immunol , vol.188 , pp. 5819-5823
    • Hawse, W.F.1    Champion, M.M.2    Joyce, M.V.3
  • 78
    • 84862636672 scopus 로고    scopus 로고
    • Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness
    • Irving M, Zoete V, Hebeisen M et al. Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness. J Biol Chem 287:23068-78.
    • J Biol Chem , vol.287 , pp. 23068-23078
    • Irving, M.1    Zoete, V.2    Hebeisen, M.3
  • 79
    • 57349118383 scopus 로고    scopus 로고
    • Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor
    • Varela-Rohena A, Molloy PE, Dunn SM et al. Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor. Nat Med 2008; 14:1390-5.
    • (2008) Nat Med , vol.14 , pp. 1390-1395
    • Varela-Rohena, A.1    Molloy, P.E.2    Dunn, S.M.3
  • 80
    • 84871338258 scopus 로고    scopus 로고
    • Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies
    • Aleksic M, Liddy N, Molloy PE et al. Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies. Eur J Immunol 42:3174-9.
    • Eur J Immunol , vol.42 , pp. 3174-3179
    • Aleksic, M.1    Liddy, N.2    Molloy, P.E.3
  • 81
    • 34247605947 scopus 로고    scopus 로고
    • Human TCR-binding affinity is governed by MHC class restriction
    • Cole DK, Pumphrey NJ, Boulter JM et al. Human TCR-binding affinity is governed by MHC class restriction. J Immunol 2007; 178:5727-34.
    • (2007) J Immunol , vol.178 , pp. 5727-5734
    • Cole, D.K.1    Pumphrey, N.J.2    Boulter, J.M.3
  • 82
    • 84930413355 scopus 로고    scopus 로고
    • TCR binding affinity governs the functional profile of cancer-specific CD8+ T cells
    • Clin Exp Immunol in press.
    • Tan MP, Gerry AB, Brewer JE et al. TCR binding affinity governs the functional profile of cancer-specific CD8+ T cells. Clin Exp Immunol in press 2014.
    • (2014)
    • Tan, M.P.1    Gerry, A.B.2    Brewer, J.E.3
  • 83
    • 84883866836 scopus 로고    scopus 로고
    • Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells
    • 197ra103
    • Cameron BJ, Gerry AB, Dukes J et al. Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells. Sci Transl Med 2013; 5:197ra103.
    • (2013) Sci Transl Med , vol.5
    • Cameron, B.J.1    Gerry, A.B.2    Dukes, J.3
  • 84
    • 84880730689 scopus 로고    scopus 로고
    • Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
    • Linette GP, Stadtmauer EA, Maus MV et al. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood 2013; 22:863-71.
    • (2013) Blood , vol.22 , pp. 863-871
    • Linette, G.P.1    Stadtmauer, E.A.2    Maus, M.V.3
  • 86
    • 84862025335 scopus 로고    scopus 로고
    • Monoclonal TCR-redirected tumor cell killing
    • Liddy N, Bossi G, Adams KJ et al. Monoclonal TCR-redirected tumor cell killing. Nat Med 2012; 18:980-7.
    • (2012) Nat Med , vol.18 , pp. 980-987
    • Liddy, N.1    Bossi, G.2    Adams, K.J.3
  • 87
    • 84908016492 scopus 로고    scopus 로고
    • Monoclonal T-cell receptor drugs pique pharma's interest
    • Sheridan C. Monoclonal T-cell receptor drugs pique pharma's interest. Nat Biotechnol 2013; 31:950-1.
    • (2013) Nat Biotechnol , vol.31 , pp. 950-951
    • Sheridan, C.1
  • 88
    • 84865369721 scopus 로고    scopus 로고
    • T cells specific for lipid antigens
    • Mori L, De Libero G. T cells specific for lipid antigens. Immunol Res 2012; 53:191-9.
    • (2012) Immunol Res , vol.53 , pp. 191-199
    • Mori, L.1    De Libero, G.2
  • 89
    • 84923575748 scopus 로고    scopus 로고
    • αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands
    • Birkinshaw RW, Pellicci DG, Cheng TY et al. αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat Immunol 2015; 16:258-66.
    • (2015) Nat Immunol , vol.16 , pp. 258-266
    • Birkinshaw, R.W.1    Pellicci, D.G.2    Cheng, T.Y.3
  • 90
    • 0035984523 scopus 로고    scopus 로고
    • Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains
    • Gadola SD, Zaccai NR, Harlos K et al. Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. Nat Immunol 2002; 3:721-6.
    • (2002) Nat Immunol , vol.3 , pp. 721-726
    • Gadola, S.D.1    Zaccai, N.R.2    Harlos, K.3
  • 91
    • 84908530415 scopus 로고    scopus 로고
    • Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by αβ T cells
    • Roy S, Ly D, Li NS et al. Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by αβ T cells. Proc Natl Acad Sci USA 2014; 11:E4648-57.
    • (2014) Proc Natl Acad Sci USA , vol.11 , pp. E4648-E4657
    • Roy, S.1    Ly, D.2    Li, N.S.3
  • 92
    • 84890207005 scopus 로고    scopus 로고
    • Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells
    • Luoma AM, Castro CD, Mayassi T et al. Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells. Immunity 39:1032-42.
    • Immunity , vol.39 , pp. 1032-1042
    • Luoma, A.M.1    Castro, C.D.2    Mayassi, T.3
  • 93
    • 34447131000 scopus 로고    scopus 로고
    • CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor
    • Borg NA, Wun KS, Kjer-Nielsen L et al CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 2007; 448:44-9.
    • (2007) Nature , vol.448 , pp. 44-49
    • Borg, N.A.1    Wun, K.S.2    Kjer-Nielsen, L.3
  • 94
    • 84869017389 scopus 로고    scopus 로고
    • Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex
    • Wun KS, Ross F, Patel O et al. Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex. J Biol Chem 2012; 287:39139-48.
    • (2012) J Biol Chem , vol.287 , pp. 39139-39148
    • Wun, K.S.1    Ross, F.2    Patel, O.3
  • 95
    • 84880288515 scopus 로고    scopus 로고
    • Recognition of vitamin B metabolites by mucosal-associated invariant T cells
    • Patel O, Kjer-Nielsen L, Le Nours J et al. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun 2013; 4:2142.
    • (2013) Nat Commun , vol.4 , pp. 2142
    • Patel, O.1    Kjer-Nielsen, L.2    Le Nours, J.3
  • 96
    • 16444362423 scopus 로고    scopus 로고
    • Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22
    • Adams EJ, Chien YH, Garcia KC. Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22. Science 2005; 308:227-31.
    • (2005) Science , vol.308 , pp. 227-231
    • Adams, E.J.1    Chien, Y.H.2    Garcia, K.C.3
  • 97
    • 84865414943 scopus 로고    scopus 로고
    • Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor
    • Patel O, Pellicci DG, Gras S et al. Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nat Immunol 2007; 13:857-63.
    • (2007) Nat Immunol , vol.13 , pp. 857-863
    • Patel, O.1    Pellicci, D.G.2    Gras, S.3
  • 98
    • 78650113430 scopus 로고    scopus 로고
    • The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation
    • Scharf L, Li NS, Hawk AJ et al. The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity 2010; 33:853-62.
    • (2010) Immunity , vol.33 , pp. 853-862
    • Scharf, L.1    Li, N.S.2    Hawk, A.J.3
  • 99
    • 84903754024 scopus 로고    scopus 로고
    • A novel self-lipid antigen targets human T cells against CD1c(+) leukemias
    • Lepore M, de Lalla C, Gundimeda SR et al. A novel self-lipid antigen targets human T cells against CD1c(+) leukemias. J Exp Med 2014; 211:1363-77.
    • (2014) J Exp Med , vol.211 , pp. 1363-1377
    • Lepore, M.1    de Lalla, C.2    Gundimeda, S.R.3
  • 100
    • 84870284140 scopus 로고    scopus 로고
    • MR1 presents microbial vitamin B metabolites to MAIT cells
    • Kjer-Nielsen L, Patel O, Corbett AJ et al. MR1 presents microbial vitamin B metabolites to MAIT cells. Nature 2012; 491:717-23.
    • (2012) Nature , vol.491 , pp. 717-723
    • Kjer-Nielsen, L.1    Patel, O.2    Corbett, A.J.3
  • 101
    • 84861754240 scopus 로고    scopus 로고
    • Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor
    • Reantragoon R, Kjer-Nielsen L, Patel O et al. Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor. J Exp Med 2012; 209:761-74.
    • (2012) J Exp Med , vol.209 , pp. 761-774
    • Reantragoon, R.1    Kjer-Nielsen, L.2    Patel, O.3
  • 103
    • 84905122431 scopus 로고    scopus 로고
    • A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
    • Eckle SB, Birkinshaw RW, Kostenko L et al. A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. J Exp Med 2014; 211:1585-600.
    • (2014) J Exp Med , vol.211 , pp. 1585-1600
    • Eckle, S.B.1    Birkinshaw, R.W.2    Kostenko, L.3
  • 104
    • 84900551126 scopus 로고    scopus 로고
    • T-cell activation by transitory neo-antigens derived from distinct microbial pathways
    • Corbett AJ, Eckle SB, Birkinshaw RW et al. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 2014; 509:361-5.
    • (2014) Nature , vol.509 , pp. 361-365
    • Corbett, A.J.1    Eckle, S.B.2    Birkinshaw, R.W.3
  • 105
    • 84924601466 scopus 로고    scopus 로고
    • The thymus medulla fosters generation of natural Treg cells, invariant γδ T Cells and invariant NKT cells: what we learn from intrathymic migration
    • Cowan JE, Jenkinson WE, Anderson . The thymus medulla fosters generation of natural Treg cells, invariant γδ T Cells and invariant NKT cells: what we learn from intrathymic migration. Eur J Immunol 2015; 45:652-60.
    • (2015) Eur J Immunol , vol.45 , pp. 652-660
    • Cowan, J.E.1    Jenkinson, W.E.2    Anderson3
  • 106
    • 84857332436 scopus 로고    scopus 로고
    • γδ T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion
    • Sandstrom A, Scharf L, McRae G, Hawk AJ, Meredith SC, Adams EJ. γδ T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion. J Biol Chem 2012; 287:6035-43
    • (2012) J Biol Chem , vol.287 , pp. 6035-6043
    • Sandstrom, A.1    Scharf, L.2    McRae, G.3    Hawk, A.J.4    Meredith, S.C.5    Adams, E.J.6
  • 107
    • 84865419573 scopus 로고    scopus 로고
    • Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor
    • Willcox CR, Pitard V, Netzer S et al. Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor. Nat Immunol 2012; 13:872-9.
    • (2012) Nat Immunol , vol.13 , pp. 872-879
    • Willcox, C.R.1    Pitard, V.2    Netzer, S.3
  • 108
    • 84886726570 scopus 로고    scopus 로고
    • CD1d-lipid antigen recognition by the γδ TCR
    • Uldrich AP, Le Nours J, Pellicci DG et al. CD1d-lipid antigen recognition by the γδ TCR. Nat Immunol 2013; 14:1137-45.
    • (2013) Nat Immunol , vol.14 , pp. 1137-1145
    • Uldrich, A.P.1    Le Nours, J.2    Pellicci, D.G.3
  • 109
    • 0037455013 scopus 로고    scopus 로고
    • Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells
    • Gober HJ, Kistowska M, Angman L, Jenö P, Mori L, De Libero G. Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells. J Exp Med 2003; 197:163-8.
    • (2003) J Exp Med , vol.197 , pp. 163-168
    • Gober, H.J.1    Kistowska, M.2    Angman, L.3    Jenö, P.4    Mori, L.5    De Libero, G.6
  • 110
    • 0028829424 scopus 로고
    • Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells
    • Morita CT, Beckman EM, Bukowski JF et al. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity 1995; 3:495-507.
    • (1995) Immunity , vol.3 , pp. 495-507
    • Morita, C.T.1    Beckman, E.M.2    Bukowski, J.F.3
  • 111
    • 0029073751 scopus 로고
    • Natural and synthetic non-peptide antigens recognized by human gamma delta T cells
    • Tanaka Y, Morita CT, Tanaka Y, Nieves E, Brenner MB, Bloom BR. Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature 1995; 375:155-8.
    • (1995) Nature , vol.375 , pp. 155-158
    • Tanaka, Y.1    Morita, C.T.2    Tanaka, Y.3    Nieves, E.4    Brenner, M.B.5    Bloom, B.R.6
  • 112
    • 84883147590 scopus 로고    scopus 로고
    • Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells
    • Vavassori S, Kumar A, Wan GS et al. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nat Immunol 2013; 14:908-16.
    • (2013) Nat Immunol , vol.14 , pp. 908-916
    • Vavassori, S.1    Kumar, A.2    Wan, G.S.3
  • 113
    • 84899121545 scopus 로고    scopus 로고
    • The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vγ9Vδ2 T cells
    • Sandstrom A, Peigné CM, Léger A et al. The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vγ9Vδ2 T cells. Immunity 2014; 40:490-500.
    • (2014) Immunity , vol.40 , pp. 490-500
    • Sandstrom, A.1    Peigné, C.M.2    Léger, A.3
  • 114
    • 0032513388 scopus 로고    scopus 로고
    • Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells
    • Groh V, Steinle A, Bauer S, Spies T. Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. Science 1998; 279:1737-40.
    • (1998) Science , vol.279 , pp. 1737-1740
    • Groh, V.1    Steinle, A.2    Bauer, S.3    Spies, T.4
  • 115
    • 45549096965 scopus 로고    scopus 로고
    • Identification of human T cell receptor gammadelta-recognized epitopes/proteins via CDR3delta peptide-based immunobiochemical strategy
    • Chen H, He X, Wang Z et al. Identification of human T cell receptor gammadelta-recognized epitopes/proteins via CDR3delta peptide-based immunobiochemical strategy. J Biol Chem 2008; 283:12528-37.
    • (2008) J Biol Chem , vol.283 , pp. 12528-12537
    • Chen, H.1    He, X.2    Wang, Z.3
  • 116
    • 84860851413 scopus 로고    scopus 로고
    • Ectopically expressed human tumor biomarker MutS homologue 2 is a novel endogenous ligand that is recognized by human γδ T cells to induce innate anti-tumor/virus immunity
    • Dai Y, Chen H, Mo C, Cui L, He W. Ectopically expressed human tumor biomarker MutS homologue 2 is a novel endogenous ligand that is recognized by human γδ T cells to induce innate anti-tumor/virus immunity. J Biol Chem 2012; 287:16812-9.
    • (2012) J Biol Chem , vol.287 , pp. 16812-16819
    • Dai, Y.1    Chen, H.2    Mo, C.3    Cui, L.4    He, W.5
  • 117
    • 84861728917 scopus 로고    scopus 로고
    • Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) signaling pathways
    • Mo C, Dai Y, Kang N, Cui L, He W. Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) signaling pathways. J Biol Chem 2012; 287:19242-54.
    • (2012) J Biol Chem , vol.287 , pp. 19242-19254
    • Mo, C.1    Dai, Y.2    Kang, N.3    Cui, L.4    He, W.5
  • 118
    • 84899024403 scopus 로고    scopus 로고
    • Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells
    • Lu J, Das M, Kanji S et al. Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells. Biochim Biophys Acta 2014; 1842:1071-9.
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 1071-1079
    • Lu, J.1    Das, M.2    Kanji, S.3
  • 119
    • 79952304774 scopus 로고    scopus 로고
    • Crystal structure of a gammadelta T-cell receptor specific for the human MHC class I homolog MICA
    • Xu B, Pizarro JC, Holmes MA et al. Crystal structure of a gammadelta T-cell receptor specific for the human MHC class I homolog MICA. Proc Natl Acad Sci USA 2011; 108:2414-9.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 2414-2419
    • Xu, B.1    Pizarro, J.C.2    Holmes, M.A.3
  • 120
    • 84862297455 scopus 로고    scopus 로고
    • Target specificity of an autoreactive pathogenic human γδ-T cell receptor in myositis
    • Bruder J, Siewert K, Obermeier B et al. Target specificity of an autoreactive pathogenic human γδ-T cell receptor in myositis. J Biol Chem 2012; 287:20986-95.
    • (2012) J Biol Chem , vol.287 , pp. 20986-20995
    • Bruder, J.1    Siewert, K.2    Obermeier, B.3
  • 121
    • 84900856985 scopus 로고    scopus 로고
    • γδ T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation
    • Aydintug MK, Zhang L, Wang C et al. γδ T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation. Mol Immunol 2014; 60:116-28.
    • (2014) Mol Immunol , vol.60 , pp. 116-128
    • Aydintug, M.K.1    Zhang, L.2    Wang, C.3
  • 122
    • 84925355715 scopus 로고    scopus 로고
    • Role of gamma-delta (γδ) T cells in autoimmunity
    • Paul S, Shilpi, Lal G. Role of gamma-delta (γδ) T cells in autoimmunity. J Leukoc Biol 2014; 97:259-71.
    • (2014) J Leukoc Biol , vol.97 , pp. 259-271
    • Paul, S.1    Shilpi2    Lal, G.3


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