Crystal structure of a αδ T-cell receptor specific for the human MHC class I homolog MICA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 6, 2011, Pages 2414-2419

  Xu, Bin ^a,b   Pizarro, Juan C ^a   Holmes, Margaret A ^a   McBeth, Christine ^a,c   Groh, Veronika ^a   Spies, Thomas ^a   Strong, Roland K ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Biacore; Crystallography

Indexed keywords

HLA A ANTIGEN; NATURAL KILLER CELL RECEPTOR NKG2D; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR GAMMA DELTA; UNCLASSIFIED DRUG; HLA ANTIGEN CLASS 1; KLRK1 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; MHC CLASS I RELATED CHAIN A; MHC CLASS I-RELATED CHAIN A; MICB ANTIGEN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K;

ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; CHEMISTRY; COMPLEMENTARITY DETERMINING REGION; IMMUNOLOGY; INNATE IMMUNITY; NEOPLASM; PROTEIN QUATERNARY STRUCTURE; T LYMPHOCYTE; VIRUS INFECTION; X RAY CRYSTALLOGRAPHY;

COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLOGRAPHY, X-RAY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNITY, INNATE; NEOPLASMS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES; VIRUS DISEASES;

EID: 79952304774     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1015433108     Document Type: Article

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