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Volumn 211, Issue 2, 2014, Pages 329-343

The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification

Author keywords

[No Author keywords available]

Indexed keywords

5'-NUCLEOTIDASE; ANIMALS; CELL LINEAGE; LIGANDS; LYMPHOPOIESIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MODELS, IMMUNOLOGICAL; PRECURSOR CELLS, T-LYMPHOID; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS;

EID: 84893754754     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131540     Document Type: Article
Times cited : (71)

References (56)
  • 1
    • 45549106387 scopus 로고    scopus 로고
    • An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells
    • Adams, E.J., P. Strop, S. Shin, Y.H. Chien, and K.C. Garcia. 2008. An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells. Nat. Immunol. 9:777-784. http://dx.doi.org/10.1038/ni.1620
    • (2008) Nat. Immunol. , vol.9 , pp. 777-784
    • Adams, E.J.1    Strop, P.2    Shin, S.3    Chien, Y.H.4    Garcia, K.C.5
  • 4
    • 77954143558 scopus 로고    scopus 로고
    • Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity
    • Bonneville, M., R.L. O'Brien, and W.K. Born. 2010. Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 10:467-478. http://dx.doi.org/10.1038/nri2781
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 467-478
    • Bonneville, M.1    O'Brien, R.L.2    Born, W.K.3
  • 5
    • 30044437014 scopus 로고    scopus 로고
    • The function of gammadelta T cells in innate immunity
    • Born, W.K., C.L. Reardon, and R.L. O'Brien. 2006. The function of gammadelta T cells in innate immunity. Curr. Opin. Immunol. 18:31-38. http://dx.doi.org/10.1016/j.coi.2005.11.007
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 31-38
    • Born, W.K.1    Reardon, C.L.2    O'Brien, R.L.3
  • 6
    • 42649092113 scopus 로고    scopus 로고
    • Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells
    • Boyden, L.M., J.M. Lewis, S.D. Barbee, A. Bas, M. Girardi, A.C. Hayday, R.E. Tigelaar, and R.P. Lifton. 2008. Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells. Nat. Genet. 40:656-662. http://dx.doi .org/10.1038/ng.108
    • (2008) Nat. Genet. , vol.40 , pp. 656-662
    • Boyden, L.M.1    Lewis, J.M.2    Barbee, S.D.3    Bas, A.4    Girardi, M.5    Hayday, A.C.6    Tigelaar, R.E.7    Lifton, R.P.8
  • 7
    • 0030273082 scopus 로고    scopus 로고
    • The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells
    • Bruno, L., H.J. Fehling, and H. von Boehmer. 1996. The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells. Immunity. 5:343-352. http://dx.doi.org/10 .1016/S1074-7613(00)80260-5
    • (1996) Immunity. , vol.5 , pp. 343-352
    • Bruno, L.1    Fehling, H.J.2    von Boehmer, H.3
  • 8
    • 0036582288 scopus 로고    scopus 로고
    • Gammadelta T cells: functional plasticity and heterogeneity
    • Carding, S.R., and P.J. Egan. 2002. Gammadelta T cells: functional plasticity and heterogeneity. Nat. Rev. Immunol. 2:336-345. http://dx.doi .org/10.1038/nri797
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 336-345
    • Carding, S.R.1    Egan, P.J.2
  • 9
    • 84858795377 scopus 로고    scopus 로고
    • Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression
    • Chalmin, F., G. Mignot, M. Bruchard, A. Chevriaux, F. Végran, A. Hichami, S. Ladoire, V. Derangère, J. Vincent, D. Masson, et al. 2012. Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. Immunity. 36:362-373. http:// dx.doi.org/10.1016/j.immuni.2011.12.019
    • (2012) Immunity. , vol.36 , pp. 362-373
    • Chalmin, F.1    Mignot, G.2    Bruchard, M.3    Chevriaux, A.4    Végran, F.5    Hichami, A.6    Ladoire, S.7    Derangère, V.8    Vincent, J.9    Masson, D.10
  • 10
    • 33745014890 scopus 로고    scopus 로고
    • Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation
    • Ciofani, M., G.C. Knowles, D.L. Wiest, H. von Boehmer, and J.C. Zúñiga-Pflücker. 2006. Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation. Immunity. 25:105-116. http://dx.doi.org/10.1016/j.immuni.2006.05.010
    • (2006) Immunity. , vol.25 , pp. 105-116
    • Ciofani, M.1    Knowles, G.C.2    Wiest, D.L.3    von Boehmer, H.4    Zúñiga-Pflücker, J.C.5
  • 11
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio, S., K.M. Dwyer, W. Gao, D. Friedman, A. Usheva, A. Erat, J.F. Chen, K. Enjyoji, J. Linden, M. Oukka, et al. 2007. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J. Exp. Med. 204:1257-1265. http://dx.doi .org/10.1084/jem.20062512
    • (2007) J. Exp. Med. , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6    Chen, J.F.7    Enjyoji, K.8    Linden, J.9    Oukka, M.10
  • 13
    • 0029311234 scopus 로고
    • Alpha beta and gamma delta T cells can share a late common precursor
    • Dudley, E.C., M. Girardi, M.J. Owen, and A.C. Hayday. 1995. Alpha beta and gamma delta T cells can share a late common precursor. Curr. Biol. 5:659-669. http://dx.doi.org/10.1016/S0960-9822(95)00131-X
    • (1995) Curr. Biol. , vol.5 , pp. 659-669
    • Dudley, E.C.1    Girardi, M.2    Owen, M.J.3    Hayday, A.C.4
  • 14
    • 33750341981 scopus 로고    scopus 로고
    • TCRgamma silencing during alphabeta T cell development depends upon pre-TCR-induced proliferation
    • Ferrero, I., S.J. Mancini, F. Grosjean, A. Wilson, L. Otten, and H.R. MacDonald. 2006. TCRgamma silencing during alphabeta T cell development depends upon pre-TCR-induced proliferation. J. Immunol. 177:6038-6043.
    • (2006) J. Immunol. , vol.177 , pp. 6038-6043
    • Ferrero, I.1    Mancini, S.J.2    Grosjean, F.3    Wilson, A.4    Otten, L.5    MacDonald, H.R.6
  • 15
    • 84878257398 scopus 로고    scopus 로고
    • Deficiency in IL-17-committed Vγ4(+) γδ T cells in a spontaneous Sox13-mutant CD45.1(+) congenic mouse substrain provides protection from dermatitis
    • Gray, E.E., F. Ramírez-Valle, Y. Xu, S. Wu, Z. Wu, K.E. Karjalainen, and J.G. Cyster. 2013. Deficiency in IL-17-committed Vγ4(+) γδ T cells in a spontaneous Sox13-mutant CD45.1(+) congenic mouse substrain provides protection from dermatitis. Nat. Immunol. 14:584-592. http:// dx.doi.org/10.1038/ni.2585
    • (2013) Nat. Immunol. , vol.14 , pp. 584-592
    • Gray, E.E.1    Ramírez-Valle, F.2    Xu, Y.3    Wu, S.4    Wu, Z.5    Karjalainen, K.E.6    Cyster, J.G.7
  • 17
    • 19344367940 scopus 로고    scopus 로고
    • Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage
    • Haks, M.C., J.M. Lefebvre, J.P. Lauritsen, M. Carleton, M. Rhodes, T. Miyazaki, D.J. Kappes, and D.L. Wiest. 2005. Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage. Immunity. 22:595-606. http://dx.doi.org/10.1016/j.immuni.2005.04.003
    • (2005) Immunity. , vol.22 , pp. 595-606
    • Haks, M.C.1    Lefebvre, J.M.2    Lauritsen, J.P.3    Carleton, M.4    Rhodes, M.5    Miyazaki, T.6    Kappes, D.J.7    Wiest, D.L.8
  • 18
    • 0023690608 scopus 로고
    • Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors
    • Havran, W.L., and J.P. Allison. 1988. Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors. Nature. 335:443-445. http://dx.doi.org/10.1038/335443a0
    • (1988) Nature. , vol.335 , pp. 443-445
    • Havran, W.L.1    Allison, J.P.2
  • 19
    • 0034091286 scopus 로고    scopus 로고
    • [gamma][delta] cells: a right time and a right place for a conserved third way of protection
    • Hayday, A.C. 2000. [gamma][delta] cells: a right time and a right place for a conserved third way of protection. Annu. Rev. Immunol. 18:975-1026. http://dx.doi.org/10.1146/annurev.immunol.18.1.975
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 975-1026
    • Hayday, A.C.1
  • 20
    • 33645074677 scopus 로고    scopus 로고
    • Strength of signal: a fundamental mechanism for cell fate specification
    • Hayes, S.M., and P.E. Love. 2006. Strength of signal: a fundamental mechanism for cell fate specification. Immunol. Rev. 209:170-175. http://dx.doi .org/10.1111/j.0105-2896.2006.00356.x
    • (2006) Immunol. Rev. , vol.209 , pp. 170-175
    • Hayes, S.M.1    Love, P.E.2
  • 21
    • 19344369077 scopus 로고    scopus 로고
    • TCR signal strength influences alphabeta/ gammadelta lineage fate
    • Hayes, S.M., L. Li, and P.E. Love. 2005. TCR signal strength influences alphabeta/ gammadelta lineage fate. Immunity. 22:583-593. http://dx.doi .org/10.1016/j.immuni.2005.03.014
    • (2005) Immunity. , vol.22 , pp. 583-593
    • Hayes, S.M.1    Li, L.2    Love, P.E.3
  • 22
    • 0025212263 scopus 로고
    • T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells
    • Ishida, I., S. Verbeek, M. Bonneville, S. Itohara, A. Berns, and S. Tonegawa. 1990. T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells. Proc. Natl. Acad. Sci. USA. 87:3067-3071. http://dx.doi.org/10.1073/ pnas.87.8.3067
    • (1990) Proc. Natl. Acad. Sci. USA. , vol.87 , pp. 3067-3071
    • Ishida, I.1    Verbeek, S.2    Bonneville, M.3    Itohara, S.4    Berns, A.5    Tonegawa, S.6
  • 23
    • 0025005607 scopus 로고
    • Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor
    • Ito, K., L. Van Kaer, M. Bonneville, S. Hsu, D.B. Murphy, and S. Tonegawa. 1990. Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor. Cell. 62:549-561. http:// dx.doi.org/10.1016/0092-8674(90)90019-B
    • (1990) Cell. , vol.62 , pp. 549-561
    • Ito, K.1    Van Kaer, L.2    Bonneville, M.3    Hsu, S.4    Murphy, D.B.5    Tonegawa, S.6
  • 24
    • 46749113368 scopus 로고    scopus 로고
    • Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma
    • Jensen, K.D., X. Su, S. Shin, L. Li, S. Youssef, S. Yamasaki, L. Steinman, T. Saito, R.M. Locksley, M.M. Davis, et al. 2008. Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity. 29:90-100. http://dx.doi.org/10.1016/j.immuni.2008.04.022
    • (2008) Immunity. , vol.29 , pp. 90-100
    • Jensen, K.D.1    Su, X.2    Shin, S.3    Li, L.4    Youssef, S.5    Yamasaki, S.6    Steinman, L.7    Saito, T.8    Locksley, R.M.9    Davis, M.M.10
  • 25
    • 77955689094 scopus 로고    scopus 로고
    • gammadeltaTCR ligands and lineage commitment
    • Kreslavsky, T., and H. von Boehmer. 2010. gammadeltaTCR ligands and lineage commitment. Semin. Immunol. 22:214-221. http://dx.doi.org/10.1016/ j.smim.2010.04.001
    • (2010) Semin. Immunol. , vol.22 , pp. 214-221
    • Kreslavsky, T.1    von Boehmer, H.2
  • 26
    • 43549085301 scopus 로고    scopus 로고
    • T cell receptor-instructed αβ versus γδ lineage commitment revealed by single-cell analysis
    • Kreslavsky, T., A.I. Garbe, A. Krueger, and H. von Boehmer. 2008. T cell receptor-instructed γδ versus γδ lineage commitment revealed by single-cell analysis. J. Exp. Med. 205:1173-1186. http://dx.doi.org/10 .1084/jem.20072425
    • (2008) J. Exp. Med. , vol.205 , pp. 1173-1186
    • Kreslavsky, T.1    Garbe, A.I.2    Krueger, A.3    von Boehmer, H.4
  • 27
  • 28
    • 77951238393 scopus 로고    scopus 로고
    • Alphabeta versus gammadelta lineage choice at the first TCR-controlled checkpoint
    • Kreslavsky, T., M. Gleimer, and H. von Boehmer. 2010. Alphabeta versus gammadelta lineage choice at the first TCR-controlled checkpoint. Curr. Opin. Immunol. 22:185-192. http://dx.doi.org/10.1016/j.coi.2009.12.006
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 185-192
    • Kreslavsky, T.1    Gleimer, M.2    von Boehmer, H.3
  • 29
    • 0035284865 scopus 로고    scopus 로고
    • Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development
    • Lacorazza, H.D., C. Tucek-Szabo, L.V. Vasovic, K. Remus, and J. Nikolich-Zugich. 2001. Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development. J. Immunol. 166:3184-3193.
    • (2001) J. Immunol. , vol.166 , pp. 3184-3193
    • Lacorazza, H.D.1    Tucek-Szabo, C.2    Vasovic, L.V.3    Remus, K.4    Nikolich-Zugich, J.5
  • 30
    • 70349741015 scopus 로고    scopus 로고
    • Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent
    • Lauritsen, J.P., G.W. Wong, S.Y. Lee, J.M. Lefebvre, M. Ciofani, M. Rhodes, D.J. Kappes, J.C. Zúñiga-Pflücker, and D.L. Wiest. 2009. Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. Immunity. 31:565-575. http://dx.doi.org/10.1016/j.immuni.2009.07.010
    • (2009) Immunity. , vol.31 , pp. 565-575
    • Lauritsen, J.P.1    Wong, G.W.2    Lee, S.Y.3    Lefebvre, J.M.4    Ciofani, M.5    Rhodes, M.6    Kappes, D.J.7    Zúñiga-Pflücker, J.C.8    Wiest, D.L.9
  • 31
    • 77954656254 scopus 로고    scopus 로고
    • Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice
    • Lee, S.Y., J. Stadanlick, D.J. Kappes, and D.L. Wiest. 2010. Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice. Semin. Immunol. 22:237-246. http://dx.doi .org/10.1016/j.smim.2010.04.008
    • (2010) Semin. Immunol. , vol.22 , pp. 237-246
    • Lee, S.Y.1    Stadanlick, J.2    Kappes, D.J.3    Wiest, D.L.4
  • 32
    • 33746178062 scopus 로고    scopus 로고
    • Selection of the cutaneous intraepithelial gammadelta+ T cell repertoire by a thymic stromal determinant
    • Lewis, J.M., M. Girardi, S.J. Roberts, S.D. Barbee, A.C. Hayday, and R.E. Tigelaar. 2006. Selection of the cutaneous intraepithelial gammadelta+ T cell repertoire by a thymic stromal determinant. Nat. Immunol. 7:843-850. http://dx.doi.org/10.1038/ni1363
    • (2006) Nat. Immunol. , vol.7 , pp. 843-850
    • Lewis, J.M.1    Girardi, M.2    Roberts, S.J.3    Barbee, S.D.4    Hayday, A.C.5    Tigelaar, R.E.6
  • 33
  • 34
    • 84876780175 scopus 로고    scopus 로고
    • A network of high-mobility group box transcription factors programs innate interleukin-17 production
    • Immunological Genome Project Consortium,
    • Malhotra, N., K. Narayan, O.H. Cho, K.E. Sylvia, C. Yin, H. Melichar, M. Rashighi, V. Lefebvre, J.E. Harris, L.J. Berg, and J. Kang; Immunological Genome Project Consortium. 2013. A network of high-mobility group box transcription factors programs innate interleukin-17 production. Immunity. 38:681-693. http://dx.doi.org/10.1016/j.immuni.2013.01.010
    • (2013) Immunity. , vol.38 , pp. 681-693
    • Malhotra, N.1    Narayan, K.2    Cho, O.H.3    Sylvia, K.E.4    Yin, C.5    Melichar, H.6    Rashighi, M.7    Lefebvre, V.8    Harris, J.E.9    Berg, L.J.10    Kang, J.11
  • 35
    • 33846487941 scopus 로고    scopus 로고
    • Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13
    • Melichar, H.J., K. Narayan, S.D. Der, Y. Hiraoka, N. Gardiol, G. Jeannet, W. Held, C.A. Chambers, and J. Kang. 2007. Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13. Science. 315:230-233. http://dx.doi.org/10.1126/science.1135344
    • (2007) Science. , vol.315 , pp. 230-233
    • Melichar, H.J.1    Narayan, K.2    Der, S.D.3    Hiraoka, Y.4    Gardiol, N.5    Jeannet, G.6    Held, W.7    Chambers, C.A.8    Kang, J.9
  • 36
    • 77954659483 scopus 로고    scopus 로고
    • Ligand recognition during thymic development and gammadelta T cell function specification
    • Meyer, C., X. Zeng, and Y.H. Chien. 2010. Ligand recognition during thymic development and gammadelta T cell function specification. Semin. Immunol. 22:207-213. http://dx.doi.org/10.1016/j.smim.2010.04.002
    • (2010) Semin. Immunol. , vol.22 , pp. 207-213
    • Meyer, C.1    Zeng, X.2    Chien, Y.H.3
  • 37
    • 77954656376 scopus 로고    scopus 로고
    • Disorderly conduct in gammadelta versus alphabeta T cell lineage commitment
    • Narayan, K., and J. Kang. 2010. Disorderly conduct in gammadelta versus alphabeta T cell lineage commitment. Semin. Immunol. 22:222-227. http://dx.doi.org/10.1016/j.smim.2010.04.003
    • (2010) Semin. Immunol. , vol.22 , pp. 222-227
    • Narayan, K.1    Kang, J.2
  • 38
    • 84859890898 scopus 로고    scopus 로고
    • Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes
    • Immunological Genome Project Consortium.
    • Narayan, K., K.E. Sylvia, N. Malhotra, C.C. Yin, G. Martens, T. Vallerskog, H. Kornfeld, N. Xiong, N.R. Cohen, M.B. Brenner, et al. Immunological Genome Project Consortium. 2012. Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes. Nat. Immunol. 13:511-518. http://dx.doi.org/10.1038/ni.2247
    • (2012) Nat. Immunol. , vol.13 , pp. 511-518
    • Narayan, K.1    Sylvia, K.E.2    Malhotra, N.3    Yin, C.C.4    Martens, G.5    Vallerskog, T.6    Kornfeld, H.7    Xiong, N.8    Cohen, N.R.9    Brenner, M.B.10
  • 39
    • 77954657540 scopus 로고    scopus 로고
    • gammadelta T cell subsets: a link between TCR and function
    • O'Brien, R.L., and W.K. Born. 2010. gammadelta T cell subsets: a link between TCR and function. Semin. Immunol. 22:193-198. http://dx.doi .org/10.1016/j.smim.2010.03.006
    • (2010) Semin. Immunol. , vol.22 , pp. 193-198
    • O'Brien, R.L.1    Born, W.K.2
  • 40
    • 77955508266 scopus 로고    scopus 로고
    • Ecto-5γ-nucleotidase (CD73) attenuates allograft airway rejection through adenosine 2A receptor stimulation
    • Ohtsuka, T., P.S. Changelian, D. Bouïs, K. Noon, H. Harada, V.N. Lama, and D.J. Pinsky. 2010. Ecto-5γ-nucleotidase (CD73) attenuates allograft airway rejection through adenosine 2A receptor stimulation. J. Immunol. 185:1321-1329. http://dx.doi.org/10.4049/jimmunol.0901847
    • (2010) J. Immunol. , vol.185 , pp. 1321-1329
    • Ohtsuka, T.1    Changelian, P.S.2    Bouïs, D.3    Noon, K.4    Harada, H.5    Lama, V.N.6    Pinsky, D.J.7
  • 43
    • 14844334134 scopus 로고    scopus 로고
    • Gammadelta T cell development-having the strength to get there
    • Pennington, D.J., B. Silva-Santos, and A.C. Hayday. 2005. Gammadelta T cell development-having the strength to get there. Curr. Opin. Immunol. 17:108-115. http://dx.doi.org/10.1016/j.coi.2005.01.009
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 108-115
    • Pennington, D.J.1    Silva-Santos, B.2    Hayday, A.C.3
  • 44
    • 0026507498 scopus 로고
    • Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice
    • Pereira, P., M. Zijlstra, J. McMaster, J.M. Loring, R. Jaenisch, and S. Tonegawa. 1992. Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice. EMBO J. 11:25-31.
    • (1992) EMBO J. , vol.11 , pp. 25-31
    • Pereira, P.1    Zijlstra, M.2    McMaster, J.3    Loring, J.M.4    Jaenisch, R.5    Tonegawa, S.6
  • 45
    • 0026633291 scopus 로고
    • Commitment to the T cell receptor-alpha beta or-gamma delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes
    • Petri, H.T., R. Scollay, and K. Shortman. 1992. Commitment to the T cell receptor-alpha beta or-gamma delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes. Eur. J. Immunol. 22:2185-2188. http://dx.doi.org/10.1002/eji.1830220836
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2185-2188
    • Petri, H.T.1    Scollay, R.2    Shortman, K.3
  • 47
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
    • Schmitt, T.M., and J.C. Zúñiga-Pflücker. 2002. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity. 17:749-756. http://dx.doi.org/10.1016/S1074-7613(02)00474-0
    • (2002) Immunity. , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zúñiga-Pflücker, J.C.2
  • 48
    • 13644251707 scopus 로고    scopus 로고
    • Lymphotoxinmediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors
    • Silva-Santos, B., D.J. Pennington, and A.C. Hayday. 2005. Lymphotoxinmediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors. Science. 307:925-928. http://dx.doi.org/10.1126/science .1103978
    • (2005) Science. , vol.307 , pp. 925-928
    • Silva-Santos, B.1    Pennington, D.J.2    Hayday, A.C.3
  • 49
    • 80051893666 scopus 로고    scopus 로고
    • The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers
    • Tani-ichi, S., M. Satake, and K. Ikuta. 2011. The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers. Int. Immunol. 23:553-563. http://dx.doi.org/10.1093/intimm/dxr055
    • (2011) Int. Immunol. , vol.23 , pp. 553-563
    • Tani-ichi, S.1    Satake, M.2    Ikuta, K.3
  • 50
    • 0034698734 scopus 로고    scopus 로고
    • Premature expression of T cell receptor (TCR)γδ suppresses TCRγδ gene rearrangement but permits development of γδ lineage T cells
    • Terrence, K., C.P. Pavlovich, E.O. Matechak, and B.J. Fowlkes. 2000. Premature expression of T cell receptor (TCR)γδ suppresses TCRγδ gene rearrangement but permits development of γδ lineage T cells. J. Exp. Med. 192:537-548. http://dx.doi.org/10.1084/jem.192.4.537
    • (2000) J. Exp. Med. , vol.192 , pp. 537-548
    • Terrence, K.1    Pavlovich, C.P.2    Matechak, E.O.3    Fowlkes, B.J.4
  • 52
    • 79960447248 scopus 로고    scopus 로고
    • Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells
    • Turchinovich, G., and A.C. Hayday. 2011. Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells. Immunity. 35:59-68. http://dx.doi .org/10.1016/j.immuni.2011.04.018
    • (2011) Immunity. , vol.35 , pp. 59-68
    • Turchinovich, G.1    Hayday, A.C.2
  • 53
    • 84872930787 scopus 로고    scopus 로고
    • Six-of-the-best: unique contributions of γδ T cells to immunology
    • Vantourout, P., and A. Hayday. 2013. Six-of-the-best: unique contributions of γδ T cells to immunology. Nat. Rev. Immunol. 13:88-100. http:// dx.doi.org/10.1038/nri3384
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 88-100
    • Vantourout, P.1    Hayday, A.2
  • 54
    • 79957788310 scopus 로고    scopus 로고
    • Molecular aspects of epithelial γδ T cell regulation
    • Witherden, D.A., and W.L. Havran. 2011. Molecular aspects of epithelial γδ T cell regulation. Trends Immunol. 32:265-271. http://dx.doi .org/10.1016/j.it.2011.03.005
    • (2011) Trends Immunol. , vol.32 , pp. 265-271
    • Witherden, D.A.1    Havran, W.L.2
  • 55
    • 77954661064 scopus 로고    scopus 로고
    • gammadelta and alphabeta T cell lineage choice: resolution by a stronger sense of being
    • Wong, G.W., and J.C. Zúñiga-Pflücker. 2010. gammadelta and alphabeta T cell lineage choice: resolution by a stronger sense of being. Semin. Immunol. 22:228-236. http://dx.doi.org/10.1016/j.smim.2010.04.005
    • (2010) Semin. Immunol. , vol.22 , pp. 228-236
    • Wong, G.W.1    Zúñiga-Pflücker, J.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.