Heterogeneous distribution of INa-L determines interregional differences in rate adaptation of repolarization

Heart Rhythm

Volumn 12, Issue 6, 2015, Pages 1295-1303

  Qi, Datun ^a,b   Yang, Zhen ^a   Robinson, Victoria M ^a   Li, Jing ^a   Gao, Chuanyu ^b   Guo, Donglin ^a   Kowey, Peter R ^a,c   Yan, Gan Xin ^a,c,d  

^a LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b ZHENGZHOU UNIVERSITY   (China)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d HUBEI UNIVERSITY OF ARTS AND SCIENCE   (China)

Author keywords

Action potential duration; Dispersion of repolarization; Late sodium current; Proarrhythmia; QT interval; Rate adaptation; Reverse use dependence

Indexed keywords

DOFETILIDE; MEXILETINE; SODIUM ION; SODIUM; VOLTAGE GATED SODIUM CHANNEL BLOCKING AGENT;

ACTION POTENTIAL DURATION; ANIMAL CELL; ARTICLE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART RATE; HEART REPOLARIZATION; HEART RIGHT VENTRICLE; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; RIGHT CORONARY ARTERY; SODIUM CURRENT; WHOLE CELL PATCH CLAMP; ACTION POTENTIAL; ADAPTATION; ANIMAL; HEART ATRIUM; HEART VENTRICLE; IN VITRO STUDY; MUSCLE CELL; PHYSIOLOGY; RABBIT;

ACTION POTENTIALS; ADAPTATION, PHYSIOLOGICAL; ANIMALS; HEART ATRIA; HEART RATE; HEART VENTRICLES; IN VITRO TECHNIQUES; MEXILETINE; MUSCLE CELLS; RABBITS; SODIUM; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

EID: 84930374825     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2015.02.013     Document Type: Article

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