-
1
-
-
0032871348
-
The M cell: Its contribution to the ECG and to normal and abnormal electrical function in the heart
-
Antzelevitch C, Shimizu W, Yan G-X, Sicouri S, Weissenburger J, Nesterenko VV, Burashnikov A, Di Diego J, Saffitz J, and Thomas GP (1999) The M cell: its contribution to the ECG and to normal and abnormal electrical function in the heart. J Cardiovasc Electrophysiol 10:1124-1152.
-
(1999)
J Cardiovasc Electrophysiol
, vol.10
, pp. 1124-1152
-
-
Antzelevitch, C.1
Shimizu, W.2
Yan, G.-X.3
Sicouri, S.4
Weissenburger, J.5
Nesterenko, V.V.6
Burashnikov, A.7
Di Diego, J.8
Saffitz, J.9
Thomas, G.P.10
-
2
-
-
0029952101
-
K(V)LQT1 and IsK (minK) proteins associate to form the I(Ks) cardiac potassium current
-
Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, and Romey G (1996) K(V)LQT1 and IsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature (Lond) 384:78-80.
-
(1996)
Nature (Lond)
, vol.384
, pp. 78-80
-
-
Barhanin, J.1
Lesage, F.2
Guillemare, E.3
Fink, M.4
Lazdunski, M.5
Romey, G.6
-
5
-
-
0348129532
-
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina
-
Chaitman BR, Pepine CJ, Parker JO, Skopal J, Chumakova G, Kuch J, Wang W, Skettino SL, and Wolff AA (2004) Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina. J Am Med Assoc 291:309-316.
-
(2004)
J Am Med Assoc
, vol.291
, pp. 309-316
-
-
Chaitman, B.R.1
Pepine, C.J.2
Parker, J.O.3
Skopal, J.4
Chumakova, G.5
Kuch, J.6
Wang, W.7
Skettino, S.L.8
Wolff, A.A.9
-
6
-
-
0028914969
-
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
-
Curran ME, Splawski I, Timothy KW, Vincent GM, Green ED, and Keating MT (1995) A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell 80:795-803.
-
(1995)
Cell
, vol.80
, pp. 795-803
-
-
Curran, M.E.1
Splawski, I.2
Timothy, K.W.3
Vincent, G.M.4
Green, E.D.5
Keating, M.T.6
-
7
-
-
0001440335
-
Protective effects of ranolazine on ventricular fibrillation induced by activation of the ATP-dependent potassium channel in the rabbit heart
-
Gralinski MR, Chi L, Park JL, Friedrichs GS, Tanhehco EJ, McCormack JG, and Lucchesi BR (1996) Protective effects of ranolazine on ventricular fibrillation induced by activation of the ATP-dependent potassium channel in the rabbit heart. J Cardiovasc Pharmacol Ther 1:141-148.
-
(1996)
J Cardiovasc Pharmacol Ther
, vol.1
, pp. 141-148
-
-
Gralinski, M.R.1
Chi, L.2
Park, J.L.3
Friedrichs, G.S.4
Tanhehco, E.J.5
McCormack, J.G.6
Lucchesi, B.R.7
-
8
-
-
0025164907
-
Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence
-
Hondeghem LM and Snyders DJ (1990) Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence. Circulation 81:686-690.
-
(1990)
Circulation
, vol.81
, pp. 686-690
-
-
Hondeghem, L.M.1
Snyders, D.J.2
-
9
-
-
0035901578
-
Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic
-
Hondeghem LM, Carlsson L, and Duker G (2001) Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic. Circulation 103:2004-2013.
-
(2001)
Circulation
, vol.103
, pp. 2004-2013
-
-
Hondeghem, L.M.1
Carlsson, L.2
Duker, G.3
-
10
-
-
0021646404
-
The effects of the Anemonia sulcata toxin (ATX II) on membrane currents of isolated mammalian myocytes
-
Isenberg G and Ravens U (1984) The effects of the Anemonia sulcata toxin (ATX II) on membrane currents of isolated mammalian myocytes. J Physiol (Lond) 357:127-149.
-
(1984)
J Physiol (Lond)
, vol.357
, pp. 127-149
-
-
Isenberg, G.1
Ravens, U.2
-
11
-
-
0036152190
-
Clinical trials update: The Heart Protection Study, IONA, CARISA, ENRICHD, ACUTE, ALIVE, MADIT II and REMATCH. Impact of nicorandil on angina. Combination assessment of ranolazine in stable angina. Enhancing recovery in coronary heart disease patients. Assessment of cardioversion using transoesophageal echocardiography. Azimilide post-infarct survival evaluation.
-
Louis AA, Manousos IR, Coletta AP, Clark AL, and Cleland JG (2002) Clinical trials update: The Heart Protection Study, IONA, CARISA, ENRICHD, ACUTE, ALIVE, MADIT II and REMATCH. Impact of nicorandil on angina. Combination assessment of ranolazine in stable angina. Enhancing recovery in coronary heart disease patients. Assessment of cardioversion using transoesophageal echocardiography. Azimilide post-infarct survival evaluation. Randomized evaluation of mechanical assistance for treatment of chronic heart failure. Eur J Heart Fail 4:111-116.
-
(2002)
Eur J Heart Fail
, vol.4
, pp. 111-116
-
-
Louis, A.A.1
Manousos, I.R.2
Coletta, A.P.3
Clark, A.L.4
Cleland, J.G.5
-
12
-
-
0037015231
-
Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation
-
Makita N, Horie M, Nakamura T, Ai T, Sasaki K, Yokoi H, Sakurai M, Sakuma I, Otani H, Sawa H, et al. (2002) Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation. Circulation 106:1269-1274.
-
(2002)
Circulation
, vol.106
, pp. 1269-1274
-
-
Makita, N.1
Horie, M.2
Nakamura, T.3
Ai, T.4
Sasaki, K.5
Yokoi, H.6
Sakurai, M.7
Sakuma, I.8
Otani, H.9
Sawa, H.10
-
13
-
-
0037049999
-
Cardiac channelopathies
-
Marban E (2002) Cardiac channelopathies. Nature (Lond) 415:213-218.
-
(2002)
Nature (Lond)
, vol.415
, pp. 213-218
-
-
Marban, E.1
-
14
-
-
0032983310
-
A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional antianginal agents
-
Pepine CJ and Wolff AA (1999) A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional antianginal agents. Am J Cardiol 84:46-50.
-
(1999)
Am J Cardiol
, vol.84
, pp. 46-50
-
-
Pepine, C.J.1
Wolff, A.A.2
-
15
-
-
0029887380
-
Differential Response to Na+ Channel blockade, β-adrenergic stimulation and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long QT syndrome
-
Priori SG, Napolitano C, Cantu F, Brown AM, and Schwartz PJ (1996) Differential Response to Na+ Channel blockade, β-adrenergic stimulation and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long QT syndrome. Circ Res 78:1009-1015.
-
(1996)
Circ Res
, vol.78
, pp. 1009-1015
-
-
Priori, S.G.1
Napolitano, C.2
Cantu, F.3
Brown, A.M.4
Schwartz, P.J.5
-
16
-
-
0033844532
-
Acquired long QT syndromes and the risk of proarrhythmia
-
Roden DM (2000) Acquired long QT syndromes and the risk of proarrhythmia. J Cardiovasc Electrophysiol 11:938-940.
-
(2000)
J Cardiovasc Electrophysiol
, vol.11
, pp. 938-940
-
-
Roden, D.M.1
-
17
-
-
0025351245
-
+ current. Differential sensitivity to block by class III antiarrhythmic agents
-
+ current. Differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol 96:195-215.
-
(1990)
J Gen Physiol
, vol.96
, pp. 195-215
-
-
Sanguinetti, M.C.1
Jurkiewicz, N.K.2
-
18
-
-
0024367747
-
Recent advances in understanding the mechanisms of drug-induced torsades de pointes arrhythmias
-
Sasyniuk BI, Valois M, and Toy W (1989) Recent advances in understanding the mechanisms of drug-induced torsades de pointes arrhythmias. Am J Cardiol 64:29J-32J.
-
(1989)
Am J Cardiol
, vol.64
-
-
Sasyniuk, B.I.1
Valois, M.2
Toy, W.3
-
19
-
-
0035830365
-
Genotype-phenotype correlation in the long-QT syndrome: Gene-specific triggers for life-threatening arrhythmias
-
Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney P, Breithardt G, Keating MT, et al. (2001) Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation 103:89-95.
-
(2001)
Circulation
, vol.103
, pp. 89-95
-
-
Schwartz, P.J.1
Priori, S.G.2
Spazzolini, C.3
Moss, A.J.4
Vincent, G.M.5
Napolitano, C.6
Denjoy, I.7
Guicheney, P.8
Breithardt, G.9
Keating, M.T.10
-
20
-
-
0037100316
-
Concomitant risk factors in reports of torsades de pointes associated with macrolide use: Review of the United States Food and Drug Administration Adverse Event Reporting System
-
Shaffer D, Singer S, Korvick J, and Honig P (2002) Concomitant risk factors in reports of torsades de pointes associated with macrolide use: review of the United States Food and Drug Administration Adverse Event Reporting System. Clin Infect Dis 35:197-200.
-
(2002)
Clin Infect Dis
, vol.35
, pp. 197-200
-
-
Shaffer, D.1
Singer, S.2
Korvick, J.3
Honig, P.4
-
21
-
-
0030796370
-
Dominant-negative KvLQT1 mutations underlie the LQT1 form of long QT syndrome
-
Shalaby FY, Levesque PC, Yang WP, Little WA, Conder ML, Jenkins-West T, and Blanar MA (1997) Dominant-negative KvLQT1 mutations underlie the LQT1 form of long QT syndrome. Circulation 96:1733-1736.
-
(1997)
Circulation
, vol.96
, pp. 1733-1736
-
-
Shalaby, F.Y.1
Levesque, P.C.2
Yang, W.P.3
Little, W.A.4
Conder, M.L.5
Jenkins-West, T.6
Blanar, M.A.7
-
22
-
-
0030819433
-
Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de pointes in LQT2 and LQT3 models of the long-QT syndrome
-
Shimizu W and Antzelevitch C (1997) Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de pointes in LQT2 and LQT3 models of the long-QT syndrome. Circulation 96:2038-2047.
-
(1997)
Circulation
, vol.96
, pp. 2038-2047
-
-
Shimizu, W.1
Antzelevitch, C.2
-
24
-
-
0035143074
-
Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome
-
Studenik CR, Zhou Z, and January CT (2001) Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome. Br J Pharmacol 132:85-92.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 85-92
-
-
Studenik, C.R.1
Zhou, Z.2
January, C.T.3
-
25
-
-
0035052435
-
Chromanol 293B inhibits slowly activating delayed rectifier and transient outward currents in canine left ventricular myocytes
-
Sun ZQ, Thomas GP, and Antzelevitch C (2001) Chromanol 293B inhibits slowly activating delayed rectifier and transient outward currents in canine left ventricular myocytes. J Cardiovasc Electrophysiol 12:472-478.
-
(2001)
J Cardiovasc Electrophysiol
, vol.12
, pp. 472-478
-
-
Sun, Z.Q.1
Thomas, G.P.2
Antzelevitch, C.3
-
26
-
-
0036853483
-
Gating of the late Na+ channel in normal and failing human myocardium
-
Undrovinas AI, Maltsev VA, Kyle JW, Silverman N, and Sabbah HN (2002) Gating of the late Na+ channel in normal and failing human myocardium. J Mol Cell Cardiol 34:1477-1489.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 1477-1489
-
-
Undrovinas, A.I.1
Maltsev, V.A.2
Kyle, J.W.3
Silverman, N.4
Sabbah, H.N.5
-
27
-
-
0035960660
-
Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome
-
van Opstal JM, Schoenmakers M, Verduyn SC, de Groot SH, Leunissen JD, van der Hulst FF, Molenschot MM, Wellens HJ, and Vos MA (2001) Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome. Circulation 104:2722-2727.
-
(2001)
Circulation
, vol.104
, pp. 2722-2727
-
-
Van Opstal, J.M.1
Schoenmakers, M.2
Verduyn, S.C.3
De Groot, S.H.4
Leunissen, J.D.5
Van Der Hulst, F.F.6
Molenschot, M.M.7
Wellens, H.J.8
Vos, M.A.9
-
28
-
-
0035726691
-
Electrophysiologic parameters and predisposing factors in the generation of drug-induced Torsade de Pointes arrhythmias
-
Vos MA, van Opstal JM, Leunissen JD, and Verduyn SC (2001) Electrophysiologic parameters and predisposing factors in the generation of drug-induced Torsade de Pointes arrhythmias. Pharmacol Ther 92:109-122.
-
(2001)
Pharmacol Ther
, vol.92
, pp. 109-122
-
-
Vos, M.A.1
Van Opstal, J.M.2
Leunissen, J.D.3
Verduyn, S.C.4
-
29
-
-
0030968494
-
Pharmacological targeting of long QT mutant sodium channels
-
Wang DW, Yazawa K, Makita N, George AL Jr, and Bennett PB (1997) Pharmacological targeting of long QT mutant sodium channels. J Clin Investig 99:1714-1720.
-
(1997)
J Clin Investig
, vol.99
, pp. 1714-1720
-
-
Wang, D.W.1
Yazawa, K.2
Makita, N.3
George Jr., A.L.4
Bennett, P.B.5
-
30
-
-
0028905566
-
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
-
Wang Q, Shen J, Splawski I, Atkinson D, Li Z, Robinson JL, Moss AJ, Towbin JA, and Keating MT (1995) SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell 80:805-811.
-
(1995)
Cell
, vol.80
, pp. 805-811
-
-
Wang, Q.1
Shen, J.2
Splawski, I.3
Atkinson, D.4
Li, Z.5
Robinson, J.L.6
Moss, A.J.7
Towbin, J.A.8
Keating, M.T.9
-
31
-
-
0141565359
-
Molecular basis of species-specific expression of repolarizing K+ currents in the heart
-
Zicha S, Moss I, Allen B, Varro A, Papp J, Dumaine R, Antzelevich C, and Nattel S (2003) Molecular basis of species-specific expression of repolarizing K+ currents in the heart. Am J Physiol 285: H1641-H1649.
-
(2003)
Am J Physiol
, vol.285
-
-
Zicha, S.1
Moss, I.2
Allen, B.3
Varro, A.4
Papp, J.5
Dumaine, R.6
Antzelevich, C.7
Nattel, S.8
-
32
-
-
0012187499
-
Ranolazine produces ion channel effects similar to those observed with chronic amiodarone in canine ventricular myocytes
-
Zygmunt AC, Thomas GP, Belardinelli L, Blackburn B, and Antzelevitch C (2002) Ranolazine produces ion channel effects similar to those observed with chronic amiodarone in canine ventricular myocytes (Abstract). Pacing Clin Electrophysiol 24:626.
-
(2002)
Pacing Clin Electrophysiol
, vol.24
, pp. 626
-
-
Zygmunt, A.C.1
Thomas, G.P.2
Belardinelli, L.3
Blackburn, B.4
Antzelevitch, C.5
|