Extracellular Potassium Modulation of Drug Block of IKr: Implications for Torsade de Pointes and Reverse Use-Dependence

Circulation

Volumn 93, Issue 3, 1996, Pages 407-411

  Yang, Tao ^a   Roden, Dan M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ions; Potassium; Torsade de pointes

Indexed keywords

DOFETILIDE; NISOLDIPINE; POTASSIUM CHANNEL; QUINIDINE;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; BRADYCARDIA; CLINICAL FEATURE; DRUG EFFICACY; HEART MUSCLE ISCHEMIA; HEART VENTRICLE TACHYCARDIA; HYPOKALEMIA; ION CONDUCTANCE; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; TORSADE DES POINTES;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; CELLS, CULTURED; ELECTROPHYSIOLOGY; EXTRACELLULAR SPACE; HEART; HUMANS; MICE; MYOCARDIUM; PHENETHYLAMINES; POTASSIUM; QUINIDINE; SULFONAMIDES; TORSADES DE POINTES;

EID: 0030022457     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.93.3.407     Document Type: Article

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